Mukesh Swami - Academia.edu (original) (raw)
Papers by Mukesh Swami
Advances in Respiratory Medicine
Introduction: Health care workers (HCWs) are directly involved in processes linked with diagnosis... more Introduction: Health care workers (HCWs) are directly involved in processes linked with diagnosis, management, and assistance of coronavirus disease-19 (COVID-19) patients which could have direct implications on their physical and emotional health. Emotional aspects of working in an infectious pandemic situation is often neglected in favour of the more obvious physical ramifications. This single point assessment study aimed to explore the factors related to stress, anxiety and depression among HCWs consequent to working in a pandemic. Material and methods: This was a cross-sectional study involving healthcare workers who were working in COVID-19 inpatient ward, COVID-19 screening area, suspect ward, suspect intensive care unit (ICU) and COVID-19 ICU across four hospitals in India. A web-based survey questionnaire was designed to elicit responses to daily challenges faced by HCWs. The questionnaire was regressed using machine-learning algorithm (Cat Boost) against the standardized Depression, Anxiety and Stress Scale-21 (DASS 21) which was used to quantify emotional distress experienced by them. Results: A total of 156 participants were included in this study. As per DASS-21 scoring, severe stress was seen in ∼17% of respondents. We could achieve an R 2 of 0.28 using our machinelearning model. The major factors responsible for stress were decreased time available for personal needs, increasing age, being posted out of core area of expertise, setting of COVID-19 care, increasing duty hours, increasing duty days, marital status and being a resident physician. Conclusions: Factors elicited in this study that are associated with stress in HCWs need to be addressed to provide wholesome emotional support to HCWs battling the pandemic. Targeted interventions may result in increased emotional resilience of the health-care system.
Scholars Academic Journal of Biosciences, 2021
There exists lack of readiness and challenges for the medical faculty to teach online. During COV... more There exists lack of readiness and challenges for the medical faculty to teach online. During COVID-19 pandemic, the need for constant support and training the faculty at different levels for the online teaching platform has been unanimously felt. Thus, identifying challenges of faculty and their needs is useful to achieve positive learning outcomes of online teaching. A cross-sectional online survey was conducted. The questionnaire was sent via E-mail or What’s app to the faculty who were involved in online teaching at our institute as well as other different medical institutions during the COVID-19 pandemic. Majority agreed that they have adequate knowledge and skills regarding online preparation and delivery of the classes. However, over ninety percent also felt the need to have more creative resources for online classes. More than half did not feel confident to handle technical issues. Student engagement factors were the common hurdles in online teaching and majority felt lack o...
The Coronavirus Pandemic and the Future : Virology, Epidemiology, Translational Toxicology and Therapeutics
Indian Journal of Psychiatry, 2022
Reihenfolge der grammatischen Beschreibung: Infinitiv als Stichwort; Kennzeichnung des Aspektes; ... more Reihenfolge der grammatischen Beschreibung: Infinitiv als Stichwort; Kennzeichnung des Aspektes; Verben ohne Angabe sind uv. Kennzeichnung der Konjugation a) durch Hinweis auf die Typen I-4a; b) durch Hinweis auf ein anderes Verb gleicher Konjugation, meist auf ein entsprechendes Verb ohne Präf., z. B. ySriTb (wie ßiiTb); wie bezieht sich nur auf die Konjugationsformen, nicht auf den Aspekt. Bei Verben auf-CH durch Verweis auf das entsprechende Verb ohne-CH, Z. B. öiVrbCH (wie ÖHTb), wobei-CH bzw.-cb an die Konjugationsformen anzufügen ist. Dem Wortartikel angefügte Aspektentsprechungen werden wie das Stichwort konjugiert, wenn andere Angaben fehlen; c) durch Nennung von Konjugationsformen selbst. Von Typen (a) oder Mustervb. (b) abweichende Konjugationsformen werden hinter diesen Hinweisen in der in den "Regeln" (s. u.) befolgten Reihenfolge genannt. Grundsätzlich, auch bei Hinweis auf Typen und Mustervb., gelten für die Bildung der nichtgenannten Formen die "Regeln". Die Rektion wird gekennzeichnet durch die Anführung der entsprechenden Kasus der Pronomen KTO und MTO. Anführung von Kasus nur des Pronomens KTO kennzeichnet äie Richtung des Verbs auf Beseeltes, nur von Kasus von <rro die Richtung auf Unbeseeltes. Korö/Vro bedeutet A. Aspektentsprechungen werden, von der Bedeutungsbeschreibung durch || getrennt, in gesperrter Schrift genannt. Reflexivformen werden am Schluß des Artikels, abgetrennt durch ||, durch einfache Angabe von-CH genannt, wenn eigentlich rcfl. Bedeutung (auf das Außere des Subjektes zurückgerichtete Handlung) vorliegt. Diese Reflexivform gilt, wenn nicht anders vermerkt, für alle im Artikel genannten Bedeutungen und Aspektentsprechungen, z. B. !!-CH im Artikel Mbrn> meint: MI>ITI>CH UV., BBIMUTBCH V., NOMBRRBCH v. "sich waschen, sich durch Waschen säubern". Verben auf-CH mit anderen refl.-medialen Bedeutungen treten als selbständige Stichwörter auf. Formen auf-CH zur Kennzeichnung des Passivs erscheinen nicht im Wörterbuch.
With the advancement of science, technology is gradually occupying a larger space in our life. Du... more With the advancement of science, technology is gradually occupying a larger space in our life. During COVID-19 pandemic, technology has come up as a "saviour" as it helped us to remain connected and accessible to the people around us. However, the ongoing pandemic has also become a significant contributor towards raised digital addiction among youth. Digital addiction can manifest as excessive engagement with online games, social media, or porn. It can have various forms such as cyber-sexual addiction, gaming addiction, cyber relationship addiction, information overload, etc.
Children and Youth Services Review, 2021
Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on ... more Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre-including this research content-immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
Pediatric Oncall, 2016
Aim: To study the clinical and socio-demographic profile of somatoform disorders and its associat... more Aim: To study the clinical and socio-demographic profile of somatoform disorders and its associated stressors among pediatric population in a rural setting. Settings and Design: This cross-sectional study was done from Jan 2015 to June 2015 at rural tertiary care teaching hospital. Methods and Materials: Fifty children presenting with physically unexplained symptoms during the study period were assessed. Complete physical and psychiatric assessment was done and diagnosis was made using DSM -IV TR criteria. Patient Health questionnaire-15 (PHQ-15) was used for recording presenting symptoms and severity. Data were analyzed with Statistical Package for social sciences (SPSS 17) and association between different variables was determined using Chi-square test. Results: Male: female ratio was 24:26. Forty-two (84%) of our patients were from rural background. Most common presenting symptom was fainting spells (28%) followed by pain in abdomen (20%). Stressors were elicited in 64% patients and most common stressor was strained interpersonal relations (20%) in family. Females presented with significantly more severe illness (p=0.024). Conclusions: Psychosocial stressors especially interpersonal relations are important factor which needs to be evaluated while encountering patients with somatoform disorder.
Asian Journal of Psychiatry, 2020
Indian Journal of Psychiatry, 2020
Psychiatry and Clinical Neurosciences, 2018
Asian Journal of Psychiatry, 2019
East Asian archives of psychiatry : official journal of the Hong Kong College of Psychiatrists = Dong Ya jing shen ke xue zhi : Xianggang jing shen ke yi xue yuan qi kan, 2014
Acute and transient psychotic disorder has been accepted as a distinct diagnostic entity in the I... more Acute and transient psychotic disorder has been accepted as a distinct diagnostic entity in the ICD-10. However, there are few studies delineating its demographics and factors affecting its outcome. This study aimed to examine the socio-demographic profile of patients with acute and transient psychotic disorder and the variables associated with the onset of illness and their effect on illness outcome in an Indian setting. This was a retrospective study in which case notes of patients admitted from 1 January to 31 December 2012 and diagnosed with acute and transient psychotic disorder (according to the ICD-10 diagnostic criteria) were analysed. Socio-demographic variables and variables associated with the onset of illness were noted. Duration of hospital stay was used as a proxy measure for clinical outcome. A total of 185 patient records were analysed. Overall, 49% of the patients were males and 51% were females. Most of the cases (60%) were aged between 20 and 39 years. The majorit...
East Asian archives of psychiatry : official journal of the Hong Kong College of Psychiatrists = Dong Ya jing shen ke xue zhi : Xianggang jing shen ke yi xue yuan qi kan, 2012
To evaluate the status of schizotypy, neurological soft signs, and cognitive functions as vulnera... more To evaluate the status of schizotypy, neurological soft signs, and cognitive functions as vulnerability markers for schizophrenia and to investigate the potential value of their combination for early identification of people at high risk for schizophrenia. A cross-sectional study was conducted. Subjects were drawn from first-degree relatives of inpatients and outpatients with schizophrenia (n = 50). Controls (n = 30) were recruited by word-of-mouth from hospital staff and attendants of hospitalised patients. Subjects who met inclusion criteria on screening were subjected to selected measures for assessment, including Schizotypal Personality Questionnaire-Brief Version, the Cambridge Neurological Inventory, digit span test, paired associate learning test, and visuospatial working memory matrix. Statistical analysis was completed using the independent t test and significance (p value), as well as calculation of effect size (Cohen's d). Discriminant function analysis was used to de...
East Asian archives of psychiatry : official journal of the Hong Kong College of Psychiatrists = Dong Ya jing shen ke xue zhi : Xianggang jing shen ke yi xue yuan qi kan, 2010
To assess and compare the quality of life and disability in patients with schizophrenia and obses... more To assess and compare the quality of life and disability in patients with schizophrenia and obsessive compulsive disorder. A cross-sectional study was carried out in the outpatient psychiatry clinics at Jaipur of India. Fifty patients with obsessive compulsive disorder and 47 with schizophrenia (diagnosed as per criteria of the 10th revision of the International Classification of Diseases), and with a minimum duration of 2 years on maintenance treatments, were evaluated. Evaluation was based on the World Health Organization Quality of Life Instrument, the Global Assessment of Functioning scale, and the Indian Disability Evaluation Assessment Scale. The collected data were analysed using descriptive and inferential statistics. Regarding quality of life domains, there was no statistically significant difference between the 2 groups. Obsessive compulsive disorder patients had lower scores on all domains of disability, all such differences being statistically significant. The deleteriou...
Background: Although cognitive deficits are not yet included in the diagnostic criteria for schiz... more Background: Although cognitive deficits are not yet included in the diagnostic criteria for schizophrenia, they are consid-ered a core feature of schizophrenia symptomatology. Cognitive flexibility is a core executive function. This study was planned to assess and compare impairment in cognitive flexibility in young first episode (FE) and multi episode (ME) schizophrenia patients. Methods: We recruited 100 young (aged from 18 to 35 years) schizophrenic outpatients of either sex (diagnosed as per ICD-10 criteria) and 50 control subjects for this cross-sectional study. The cases were assessed with study instruments like the PANSS for psychopathology and the Trail Making Test-B (TMT-B) for cognitive flexibility. Results: FE patients had significantly more negative symptom scores (p=0.039) and general psychopathology scores (p=0.0001) than ME patients. FE patients performed better than ME patients on TMT-B, but there was no signif-icant difference between the two groups. Control group p...
Depression Research and Treatment, 2014
Introduction. Major depressive disorder (MDD) and bipolar affective disorder (BAD) are among the ... more Introduction. Major depressive disorder (MDD) and bipolar affective disorder (BAD) are among the leading causes of disability. These are often associated with widespread impairments in all domains of functioning including relational, occupational, and social. The main aim of the study was to examine and compare nature and extent of psychosocial impairment of patients with MDD and BAD during depressive phase.Methodology. 96 patients (48 in MDD group and 48 in BAD group) were included in the study. Patients were recruited in depressive phase (moderate to severe depression). Patients having age outside 18–45 years, psychotic symptoms, mental retardation, and current comorbid medical or axis-1 psychiatric disorder were excluded. Psychosocial functioning was assessed using Range of Impaired Functioning Tool (LIFE-RIFT).Results. Domains of work, interpersonal relationship, life satisfaction, and recreation were all affected in both groups, but the groups showed significant difference in g...
South African Journal of Psychiatry, 2014
Seasonality in mood disorders was initially studied in the context of seasonal affective disorder... more Seasonality in mood disorders was initially studied in the context of seasonal affective disorder (SAD), but later work has demonstrated that seasonality can be considered as a continuum and patients with mood disorders not diagnosed as SAD also have seasonal worsening of symptoms. [1-3] Approximately 10% of all affective disorders show a seasonal pattern of recurrence. Half of these are recurrent depressive disorders; the other half are bipolar disorders (BDs). [4] It is important to identify seasonal changes in mood and behavioural pattern in patients with these disorders because seasonality affects prognosis and implies a more severe or complex disorder. [5] Recognition of factors affecting seasonality also appears to be clinically relevant since these factors might predict recurrence of an affective episode. [6] With the objective of assessing seasonality and its contributing factors in patients with BD, we did a cross-sectional study involving 49 euthymic patients with BD diagnosed according to International Statistical Classification of Diseases and Related Health Problems (ICD)-10 criteria. Methods Patients were selected from those who came for follow-up visits to the
ipsnz.org
The aim of this study was to assess, compare and corre the plasma lev els of C-reac tive protein ... more The aim of this study was to assess, compare and corre the plasma lev els of C-reac tive protein with severity of ps ychop ogy in schizophrenia. Cross-sectional study carried out on inpatients at psychiatric centre, dept. of psychiatry, SMS Medical College, Jaipur, India. W e measured the levels of CRP in N=30 individuals with schizophrenia and in N=15 healthy control subjects as APP. The positive and negative syndrome scale [PANSS] was used in order to rate psychopathology. The data c ollec ted on above tools, were analyzed by using Pearson's correlation coefficient. The schizophrenic patients (5.93+ 8.101) had significantly high CRP levels as compared to healthy control subjects (2.53+ .816). However , CRP value did not show any correlation with ANSS positive symptom subscale, negative symptom scale, general psychopathology and total score. Elevated plasma levels of C-reactive protein in schizophrenia are not associated with the severity of symptoms. The long term consequences of elevated levels of CRP require further investigation. Acute phase protein, C-reactive protein, PANSS, Inflammation.
Mental Health and Substance Use, 2011
Advances in Respiratory Medicine
Introduction: Health care workers (HCWs) are directly involved in processes linked with diagnosis... more Introduction: Health care workers (HCWs) are directly involved in processes linked with diagnosis, management, and assistance of coronavirus disease-19 (COVID-19) patients which could have direct implications on their physical and emotional health. Emotional aspects of working in an infectious pandemic situation is often neglected in favour of the more obvious physical ramifications. This single point assessment study aimed to explore the factors related to stress, anxiety and depression among HCWs consequent to working in a pandemic. Material and methods: This was a cross-sectional study involving healthcare workers who were working in COVID-19 inpatient ward, COVID-19 screening area, suspect ward, suspect intensive care unit (ICU) and COVID-19 ICU across four hospitals in India. A web-based survey questionnaire was designed to elicit responses to daily challenges faced by HCWs. The questionnaire was regressed using machine-learning algorithm (Cat Boost) against the standardized Depression, Anxiety and Stress Scale-21 (DASS 21) which was used to quantify emotional distress experienced by them. Results: A total of 156 participants were included in this study. As per DASS-21 scoring, severe stress was seen in ∼17% of respondents. We could achieve an R 2 of 0.28 using our machinelearning model. The major factors responsible for stress were decreased time available for personal needs, increasing age, being posted out of core area of expertise, setting of COVID-19 care, increasing duty hours, increasing duty days, marital status and being a resident physician. Conclusions: Factors elicited in this study that are associated with stress in HCWs need to be addressed to provide wholesome emotional support to HCWs battling the pandemic. Targeted interventions may result in increased emotional resilience of the health-care system.
Scholars Academic Journal of Biosciences, 2021
There exists lack of readiness and challenges for the medical faculty to teach online. During COV... more There exists lack of readiness and challenges for the medical faculty to teach online. During COVID-19 pandemic, the need for constant support and training the faculty at different levels for the online teaching platform has been unanimously felt. Thus, identifying challenges of faculty and their needs is useful to achieve positive learning outcomes of online teaching. A cross-sectional online survey was conducted. The questionnaire was sent via E-mail or What’s app to the faculty who were involved in online teaching at our institute as well as other different medical institutions during the COVID-19 pandemic. Majority agreed that they have adequate knowledge and skills regarding online preparation and delivery of the classes. However, over ninety percent also felt the need to have more creative resources for online classes. More than half did not feel confident to handle technical issues. Student engagement factors were the common hurdles in online teaching and majority felt lack o...
The Coronavirus Pandemic and the Future : Virology, Epidemiology, Translational Toxicology and Therapeutics
Indian Journal of Psychiatry, 2022
Reihenfolge der grammatischen Beschreibung: Infinitiv als Stichwort; Kennzeichnung des Aspektes; ... more Reihenfolge der grammatischen Beschreibung: Infinitiv als Stichwort; Kennzeichnung des Aspektes; Verben ohne Angabe sind uv. Kennzeichnung der Konjugation a) durch Hinweis auf die Typen I-4a; b) durch Hinweis auf ein anderes Verb gleicher Konjugation, meist auf ein entsprechendes Verb ohne Präf., z. B. ySriTb (wie ßiiTb); wie bezieht sich nur auf die Konjugationsformen, nicht auf den Aspekt. Bei Verben auf-CH durch Verweis auf das entsprechende Verb ohne-CH, Z. B. öiVrbCH (wie ÖHTb), wobei-CH bzw.-cb an die Konjugationsformen anzufügen ist. Dem Wortartikel angefügte Aspektentsprechungen werden wie das Stichwort konjugiert, wenn andere Angaben fehlen; c) durch Nennung von Konjugationsformen selbst. Von Typen (a) oder Mustervb. (b) abweichende Konjugationsformen werden hinter diesen Hinweisen in der in den "Regeln" (s. u.) befolgten Reihenfolge genannt. Grundsätzlich, auch bei Hinweis auf Typen und Mustervb., gelten für die Bildung der nichtgenannten Formen die "Regeln". Die Rektion wird gekennzeichnet durch die Anführung der entsprechenden Kasus der Pronomen KTO und MTO. Anführung von Kasus nur des Pronomens KTO kennzeichnet äie Richtung des Verbs auf Beseeltes, nur von Kasus von <rro die Richtung auf Unbeseeltes. Korö/Vro bedeutet A. Aspektentsprechungen werden, von der Bedeutungsbeschreibung durch || getrennt, in gesperrter Schrift genannt. Reflexivformen werden am Schluß des Artikels, abgetrennt durch ||, durch einfache Angabe von-CH genannt, wenn eigentlich rcfl. Bedeutung (auf das Außere des Subjektes zurückgerichtete Handlung) vorliegt. Diese Reflexivform gilt, wenn nicht anders vermerkt, für alle im Artikel genannten Bedeutungen und Aspektentsprechungen, z. B. !!-CH im Artikel Mbrn> meint: MI>ITI>CH UV., BBIMUTBCH V., NOMBRRBCH v. "sich waschen, sich durch Waschen säubern". Verben auf-CH mit anderen refl.-medialen Bedeutungen treten als selbständige Stichwörter auf. Formen auf-CH zur Kennzeichnung des Passivs erscheinen nicht im Wörterbuch.
With the advancement of science, technology is gradually occupying a larger space in our life. Du... more With the advancement of science, technology is gradually occupying a larger space in our life. During COVID-19 pandemic, technology has come up as a "saviour" as it helped us to remain connected and accessible to the people around us. However, the ongoing pandemic has also become a significant contributor towards raised digital addiction among youth. Digital addiction can manifest as excessive engagement with online games, social media, or porn. It can have various forms such as cyber-sexual addiction, gaming addiction, cyber relationship addiction, information overload, etc.
Children and Youth Services Review, 2021
Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on ... more Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre-including this research content-immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
Pediatric Oncall, 2016
Aim: To study the clinical and socio-demographic profile of somatoform disorders and its associat... more Aim: To study the clinical and socio-demographic profile of somatoform disorders and its associated stressors among pediatric population in a rural setting. Settings and Design: This cross-sectional study was done from Jan 2015 to June 2015 at rural tertiary care teaching hospital. Methods and Materials: Fifty children presenting with physically unexplained symptoms during the study period were assessed. Complete physical and psychiatric assessment was done and diagnosis was made using DSM -IV TR criteria. Patient Health questionnaire-15 (PHQ-15) was used for recording presenting symptoms and severity. Data were analyzed with Statistical Package for social sciences (SPSS 17) and association between different variables was determined using Chi-square test. Results: Male: female ratio was 24:26. Forty-two (84%) of our patients were from rural background. Most common presenting symptom was fainting spells (28%) followed by pain in abdomen (20%). Stressors were elicited in 64% patients and most common stressor was strained interpersonal relations (20%) in family. Females presented with significantly more severe illness (p=0.024). Conclusions: Psychosocial stressors especially interpersonal relations are important factor which needs to be evaluated while encountering patients with somatoform disorder.
Asian Journal of Psychiatry, 2020
Indian Journal of Psychiatry, 2020
Psychiatry and Clinical Neurosciences, 2018
Asian Journal of Psychiatry, 2019
East Asian archives of psychiatry : official journal of the Hong Kong College of Psychiatrists = Dong Ya jing shen ke xue zhi : Xianggang jing shen ke yi xue yuan qi kan, 2014
Acute and transient psychotic disorder has been accepted as a distinct diagnostic entity in the I... more Acute and transient psychotic disorder has been accepted as a distinct diagnostic entity in the ICD-10. However, there are few studies delineating its demographics and factors affecting its outcome. This study aimed to examine the socio-demographic profile of patients with acute and transient psychotic disorder and the variables associated with the onset of illness and their effect on illness outcome in an Indian setting. This was a retrospective study in which case notes of patients admitted from 1 January to 31 December 2012 and diagnosed with acute and transient psychotic disorder (according to the ICD-10 diagnostic criteria) were analysed. Socio-demographic variables and variables associated with the onset of illness were noted. Duration of hospital stay was used as a proxy measure for clinical outcome. A total of 185 patient records were analysed. Overall, 49% of the patients were males and 51% were females. Most of the cases (60%) were aged between 20 and 39 years. The majorit...
East Asian archives of psychiatry : official journal of the Hong Kong College of Psychiatrists = Dong Ya jing shen ke xue zhi : Xianggang jing shen ke yi xue yuan qi kan, 2012
To evaluate the status of schizotypy, neurological soft signs, and cognitive functions as vulnera... more To evaluate the status of schizotypy, neurological soft signs, and cognitive functions as vulnerability markers for schizophrenia and to investigate the potential value of their combination for early identification of people at high risk for schizophrenia. A cross-sectional study was conducted. Subjects were drawn from first-degree relatives of inpatients and outpatients with schizophrenia (n = 50). Controls (n = 30) were recruited by word-of-mouth from hospital staff and attendants of hospitalised patients. Subjects who met inclusion criteria on screening were subjected to selected measures for assessment, including Schizotypal Personality Questionnaire-Brief Version, the Cambridge Neurological Inventory, digit span test, paired associate learning test, and visuospatial working memory matrix. Statistical analysis was completed using the independent t test and significance (p value), as well as calculation of effect size (Cohen's d). Discriminant function analysis was used to de...
East Asian archives of psychiatry : official journal of the Hong Kong College of Psychiatrists = Dong Ya jing shen ke xue zhi : Xianggang jing shen ke yi xue yuan qi kan, 2010
To assess and compare the quality of life and disability in patients with schizophrenia and obses... more To assess and compare the quality of life and disability in patients with schizophrenia and obsessive compulsive disorder. A cross-sectional study was carried out in the outpatient psychiatry clinics at Jaipur of India. Fifty patients with obsessive compulsive disorder and 47 with schizophrenia (diagnosed as per criteria of the 10th revision of the International Classification of Diseases), and with a minimum duration of 2 years on maintenance treatments, were evaluated. Evaluation was based on the World Health Organization Quality of Life Instrument, the Global Assessment of Functioning scale, and the Indian Disability Evaluation Assessment Scale. The collected data were analysed using descriptive and inferential statistics. Regarding quality of life domains, there was no statistically significant difference between the 2 groups. Obsessive compulsive disorder patients had lower scores on all domains of disability, all such differences being statistically significant. The deleteriou...
Background: Although cognitive deficits are not yet included in the diagnostic criteria for schiz... more Background: Although cognitive deficits are not yet included in the diagnostic criteria for schizophrenia, they are consid-ered a core feature of schizophrenia symptomatology. Cognitive flexibility is a core executive function. This study was planned to assess and compare impairment in cognitive flexibility in young first episode (FE) and multi episode (ME) schizophrenia patients. Methods: We recruited 100 young (aged from 18 to 35 years) schizophrenic outpatients of either sex (diagnosed as per ICD-10 criteria) and 50 control subjects for this cross-sectional study. The cases were assessed with study instruments like the PANSS for psychopathology and the Trail Making Test-B (TMT-B) for cognitive flexibility. Results: FE patients had significantly more negative symptom scores (p=0.039) and general psychopathology scores (p=0.0001) than ME patients. FE patients performed better than ME patients on TMT-B, but there was no signif-icant difference between the two groups. Control group p...
Depression Research and Treatment, 2014
Introduction. Major depressive disorder (MDD) and bipolar affective disorder (BAD) are among the ... more Introduction. Major depressive disorder (MDD) and bipolar affective disorder (BAD) are among the leading causes of disability. These are often associated with widespread impairments in all domains of functioning including relational, occupational, and social. The main aim of the study was to examine and compare nature and extent of psychosocial impairment of patients with MDD and BAD during depressive phase.Methodology. 96 patients (48 in MDD group and 48 in BAD group) were included in the study. Patients were recruited in depressive phase (moderate to severe depression). Patients having age outside 18–45 years, psychotic symptoms, mental retardation, and current comorbid medical or axis-1 psychiatric disorder were excluded. Psychosocial functioning was assessed using Range of Impaired Functioning Tool (LIFE-RIFT).Results. Domains of work, interpersonal relationship, life satisfaction, and recreation were all affected in both groups, but the groups showed significant difference in g...
South African Journal of Psychiatry, 2014
Seasonality in mood disorders was initially studied in the context of seasonal affective disorder... more Seasonality in mood disorders was initially studied in the context of seasonal affective disorder (SAD), but later work has demonstrated that seasonality can be considered as a continuum and patients with mood disorders not diagnosed as SAD also have seasonal worsening of symptoms. [1-3] Approximately 10% of all affective disorders show a seasonal pattern of recurrence. Half of these are recurrent depressive disorders; the other half are bipolar disorders (BDs). [4] It is important to identify seasonal changes in mood and behavioural pattern in patients with these disorders because seasonality affects prognosis and implies a more severe or complex disorder. [5] Recognition of factors affecting seasonality also appears to be clinically relevant since these factors might predict recurrence of an affective episode. [6] With the objective of assessing seasonality and its contributing factors in patients with BD, we did a cross-sectional study involving 49 euthymic patients with BD diagnosed according to International Statistical Classification of Diseases and Related Health Problems (ICD)-10 criteria. Methods Patients were selected from those who came for follow-up visits to the
ipsnz.org
The aim of this study was to assess, compare and corre the plasma lev els of C-reac tive protein ... more The aim of this study was to assess, compare and corre the plasma lev els of C-reac tive protein with severity of ps ychop ogy in schizophrenia. Cross-sectional study carried out on inpatients at psychiatric centre, dept. of psychiatry, SMS Medical College, Jaipur, India. W e measured the levels of CRP in N=30 individuals with schizophrenia and in N=15 healthy control subjects as APP. The positive and negative syndrome scale [PANSS] was used in order to rate psychopathology. The data c ollec ted on above tools, were analyzed by using Pearson's correlation coefficient. The schizophrenic patients (5.93+ 8.101) had significantly high CRP levels as compared to healthy control subjects (2.53+ .816). However , CRP value did not show any correlation with ANSS positive symptom subscale, negative symptom scale, general psychopathology and total score. Elevated plasma levels of C-reactive protein in schizophrenia are not associated with the severity of symptoms. The long term consequences of elevated levels of CRP require further investigation. Acute phase protein, C-reactive protein, PANSS, Inflammation.
Mental Health and Substance Use, 2011