Munenori Numata - Academia.edu (original) (raw)

Uploads

Papers by Munenori Numata

Research paper thumbnail of Microflow-driven Temporal Self-assembly of Amphiphilic Molecules

Chemistry Letters, Dec 5, 2012

A dynamic oilwater interface generated in a double-Yshaped microfluidic device allowed amphiphili... more A dynamic oilwater interface generated in a double-Yshaped microfluidic device allowed amphiphilic molecules to self-assemble spontaneously for a set period of time, leading to the creation of discrete supramolecular coordination polymers. After elution from the device, these 1-D structures gradually dissociated into their monomer units, regenerating the initial state. The self-assembled structures were maintained only under the flow conditions in the device.

Research paper thumbnail of Ionic supramolecular polymerization of water-soluble porphyrins: balancing ionic attraction and steric repulsion to govern stacking

RSC Advances

Anionic water-soluble porphyrins undergo supramolecular polymerization through two independent pa... more Anionic water-soluble porphyrins undergo supramolecular polymerization through two independent pathways—slipped stacking mediated by ionic interactions and face-to-face stacking with the assistance of hydrogen bonding of amide NH units.

Research paper thumbnail of Front Cover: Proton‐Gradient‐Driven Self‐Assembly of Porphyrin and In Situ Dynamic Analysis in a Microflow Platform (ChemSystemsChem 5/2020)

Research paper thumbnail of Proton‐Gradient‐Driven Self‐Assembly of Porphyrin and In Situ Dynamic Analysis in a Microflow Platform

Research paper thumbnail of Molecular Synchronization Enhances Molecular Interactions: An Explanatory Note of Pressure Effects

Crystals, 2018

In this study, we investigated a unique aspect of the supramolecular polymerization of tetrakis (... more In this study, we investigated a unique aspect of the supramolecular polymerization of tetrakis (4-sulfonatophenyl) porphyrin (TPPS), a self-assembling porphyrin, under non-equilibrium conditions by subtracting the effects of back-pressure on its polymerization. We focused on the enhanced self-assembly abilities of TPPS under a process of rapid proton diffusion in a microflow channel. Rapid protonation caused synchronization of many sets of protonation/deprotonation equilibria on the molecular scale, leading to the production of many sets of growing suparmolecular spices. Pressure effects in the microflow channel, which could potentially promote self-assembly of TPPS, were negligible, becoming predominant only when the system was in the synchronized state.

Research paper thumbnail of Creation of Discrete 1D Microstructures: Directional Dissociation from the Ends of a Metastable Supramolecular Polymer

ChemPlusChem, 2019

One major concern in supramolecular chemistry is how to place different intermolecular interactio... more One major concern in supramolecular chemistry is how to place different intermolecular interactions in a desired position, especially at the terminal ends, of 1D structures. A solution to the problem is co‐assembly in microflow. We demonstrate that kinetic co‐assembly of two kinds of amphiphilic oligo(p‐phenylenevinylene) molecules with different amide groups result in metastable nanofibers where stronger hydrogen‐bonding interactions are regularly inserted as stabilizing wedges. It is found that decomposition of the nanofibers from the ends is suppressed at the wedges, leading to the creation of discrete 1D structures with capped ends (length dispersity Lw/Ln≤1.2), which act as a micrometer‐sized building blocks that can be used for further hierarchical assembly.

Research paper thumbnail of Enhanced Self-Assembly Abilities Coupled with Nano- and Microscale Non-Equilibrium Phenomena in Flowing Microfields

Research paper thumbnail of Oligosaccharide Sensing in Aqueous Media by Porphyrin-Curdlan Conjugates: A Prêt-á-Porter Rather Than Haute-Couture Approach

Chemistry - A European Journal, 2017

Research paper thumbnail of Flowing microenvironments regulate the helical pitch of a semi-artificial polymer

RSC Adv., 2016

A novel strategy has been developed for tuning a polymer's conformation in a microfluidic sys... more A novel strategy has been developed for tuning a polymer's conformation in a microfluidic system. The helical pitch of a semi-artificial polymer was controlled precisely in a top-down manner under the non-equilibrium regulated in the microflow.

Research paper thumbnail of Polysaccharide-carbon nanotube complex

Research paper thumbnail of Circularly Polarized Luminescence from Supramolecular Chiral Complexes of Achiral Conjugated Polymers and a Neutral Polysaccharide

Chemistry Letters, 2010

We have developed a novel approach to the preparation of a circularly polarized luminescence mate... more We have developed a novel approach to the preparation of a circularly polarized luminescence material from a natural polysaccharide host and an achrial polythiophene guest.

Research paper thumbnail of ChemInform Abstract: Supramolecular Chemistry in Microflow Fields: Toward a New Material World of Precise Kinetic Control

Research paper thumbnail of Properly Assembled Dendrons Can Be Immobilized into Dendrimers by in situ Cross-Link

Chemistry Letters, 2000

ABSTRACT

Research paper thumbnail of Click Chemistry on Curdlan: A Regioselective and Quantitative Approach to Develop Artificial β-1,3-Glucans with Various Functional Appendages

Chemistry Letters, 2006

β-1, 3-Glucans having various functional appendages (lactoside, ferrocene, pyrene, etc.) can be p... more β-1, 3-Glucans having various functional appendages (lactoside, ferrocene, pyrene, etc.) can be prepared in an convenient, quantitative, and regioselective manner through chemo-selective [3+ 2]-cycloadditions between 6-azido-6-deoxy-curdlan and various functional ...

Research paper thumbnail of Orthogonal Polymer Recognition Based on Semiartificial Helical Polysaccharide

Chemistry Letters, 2013

ABSTRACT Two kinds of polymeric nanoarchitectures, i.e., one-dimensional polymer composites and t... more ABSTRACT Two kinds of polymeric nanoarchitectures, i.e., one-dimensional polymer composites and two-dimensional sheet-like structures, can be created using a semiartificial helical polysaccharide with one-dimensional cavities and peripheral molecular-recognition sites.

Research paper thumbnail of Semiartificial Polysaccharide Can Provide a Unique Nanospace for the Construction of Supramolecular Dye-assembly

Chemistry Letters, 2010

ABSTRACT We have revealed unique template effects of a semiartificial polysaccharide on the self-... more ABSTRACT We have revealed unique template effects of a semiartificial polysaccharide on the self-assembly of anionic cyanine dyes. The inner space of the polysaccharide acts not only as a nanotemplate for the dye assembly but also as a protective space from unfavorable photobleaching.

Research paper thumbnail of β-1,3-Glucan Schizophyllan Can Act as a One-dimensional Host to Arrange Icosahedral Carboranes

Chemistry Letters, 2007

ABSTRACT We here demonstrate that schizophyllan (SPG: one kind of beta-1, 3-glucans) /m-carborane... more ABSTRACT We here demonstrate that schizophyllan (SPG: one kind of beta-1, 3-glucans) /m-carborane nanocomposites can be easily created in a supramolecular manner by utilizing the unique wrapping capability of SPG. TEM observations revealed that incorporated in-carborane molecules adopt continuous one-dimensional (I-D) arrangement in the SPG hydrophobic cavity. We believe that the present system can provide a novel concept not only for the separation of carborane isomers and the construction of one-dimensional architectures but also for the new formulation of boron neutron capture therapy (BNCT) agents.

Research paper thumbnail of Post-polymerization of preorganized assemblies for creating shape-controlled functional materials

Chemical Society Reviews, 2007

Organic chemistry Z 0200 Post-Polymerization of Preorganized Assemblies for Creating Shape-Contro... more Organic chemistry Z 0200 Post-Polymerization of Preorganized Assemblies for Creating Shape-Controlled Functional Materials -[about 100 refs.]. -(SADA, K.; TAKEUCHI, M.; FUJITA, N.; NUMATA, M.; SHINKAI*, S.; Chem. Soc. Rev. 36 (2007) 2, 415-435; Dep. Chem. Biochem., Grad. Sch. Eng., Kyushu Univ., Fukuoka 812-81, Japan; Eng.) -Lindner 21-236

Research paper thumbnail of β-1,3-Glucan polysaccharides as novel one-dimensional hosts for DNA/RNA, conjugated polymers and nanoparticles

Chemical Communications, 2005

b-1,3-Glucan polysaccharides have triple-stranded helical structures whose sense and pitch are co... more b-1,3-Glucan polysaccharides have triple-stranded helical structures whose sense and pitch are comparable to those of polynucleotides. We recently revealed that the b-1,3-glucans could interact with certain polynucleotides to form triple-stranded and helical macromolecular complexes consisting of two polysaccharide-strands and one polynucleotide-strand. This unique property of the b-1,3-glucans has made it possible to utilize these polysaccharides as potential carriers for various functional polynucleotides. In paticular, cell-uptake efficiency of the resultant polysaccharide/polynucleotide complexes was remarkably enhanced when functional groups recognized in a biological system were introduced as pendent groups. The b-1,3-glucans can also interact with various one-dimensional architectures, such as single-walled carbon nanotubes, to produce unique nanocomposites, in which the single-walled carbon nanotubes are entrapped within the helical superstructure of b-1,3-glucans. Various conductive polymers and gold nanoparticles are also entrapped within the helical superstructure in a similar manner. In addition, diacetylene monomers entrapped within the helical superstructure can be photopolymerized to afford the corresponding poly(diacetylene)-nanofibers with a uniform diameter. These findings indicate that the b-1,3-glucans are very attractive and useful materials not only in biotechnology but also in nanotechnology. These unique properties of the b-1,3-glucans undoubtedly originate from their inherent, very strong helix-forming character which has never been observed for other polysaccharides.

Research paper thumbnail of Complementary hydrogen-bonding between thymidine-based low molecular-weight gelator and polynucleotide in organic mediaElectronic supplementary information (ESI) available: IR spectral changes in 1 gel induced by poly(A)/lipid addition; TEM images of 1 gel and 1 with poly(A)/lipid (1.0 eq.) gel, ...

Chemical Communications, 2004

We have found that aggregation mode and gelation property of thymidine-based organogelator are af... more We have found that aggregation mode and gelation property of thymidine-based organogelator are affected by the addition of its complementary polynucleotide in organic media.

Research paper thumbnail of Microflow-driven Temporal Self-assembly of Amphiphilic Molecules

Chemistry Letters, Dec 5, 2012

A dynamic oilwater interface generated in a double-Yshaped microfluidic device allowed amphiphili... more A dynamic oilwater interface generated in a double-Yshaped microfluidic device allowed amphiphilic molecules to self-assemble spontaneously for a set period of time, leading to the creation of discrete supramolecular coordination polymers. After elution from the device, these 1-D structures gradually dissociated into their monomer units, regenerating the initial state. The self-assembled structures were maintained only under the flow conditions in the device.

Research paper thumbnail of Ionic supramolecular polymerization of water-soluble porphyrins: balancing ionic attraction and steric repulsion to govern stacking

RSC Advances

Anionic water-soluble porphyrins undergo supramolecular polymerization through two independent pa... more Anionic water-soluble porphyrins undergo supramolecular polymerization through two independent pathways—slipped stacking mediated by ionic interactions and face-to-face stacking with the assistance of hydrogen bonding of amide NH units.

Research paper thumbnail of Front Cover: Proton‐Gradient‐Driven Self‐Assembly of Porphyrin and In Situ Dynamic Analysis in a Microflow Platform (ChemSystemsChem 5/2020)

Research paper thumbnail of Proton‐Gradient‐Driven Self‐Assembly of Porphyrin and In Situ Dynamic Analysis in a Microflow Platform

Research paper thumbnail of Molecular Synchronization Enhances Molecular Interactions: An Explanatory Note of Pressure Effects

Crystals, 2018

In this study, we investigated a unique aspect of the supramolecular polymerization of tetrakis (... more In this study, we investigated a unique aspect of the supramolecular polymerization of tetrakis (4-sulfonatophenyl) porphyrin (TPPS), a self-assembling porphyrin, under non-equilibrium conditions by subtracting the effects of back-pressure on its polymerization. We focused on the enhanced self-assembly abilities of TPPS under a process of rapid proton diffusion in a microflow channel. Rapid protonation caused synchronization of many sets of protonation/deprotonation equilibria on the molecular scale, leading to the production of many sets of growing suparmolecular spices. Pressure effects in the microflow channel, which could potentially promote self-assembly of TPPS, were negligible, becoming predominant only when the system was in the synchronized state.

Research paper thumbnail of Creation of Discrete 1D Microstructures: Directional Dissociation from the Ends of a Metastable Supramolecular Polymer

ChemPlusChem, 2019

One major concern in supramolecular chemistry is how to place different intermolecular interactio... more One major concern in supramolecular chemistry is how to place different intermolecular interactions in a desired position, especially at the terminal ends, of 1D structures. A solution to the problem is co‐assembly in microflow. We demonstrate that kinetic co‐assembly of two kinds of amphiphilic oligo(p‐phenylenevinylene) molecules with different amide groups result in metastable nanofibers where stronger hydrogen‐bonding interactions are regularly inserted as stabilizing wedges. It is found that decomposition of the nanofibers from the ends is suppressed at the wedges, leading to the creation of discrete 1D structures with capped ends (length dispersity Lw/Ln≤1.2), which act as a micrometer‐sized building blocks that can be used for further hierarchical assembly.

Research paper thumbnail of Enhanced Self-Assembly Abilities Coupled with Nano- and Microscale Non-Equilibrium Phenomena in Flowing Microfields

Research paper thumbnail of Oligosaccharide Sensing in Aqueous Media by Porphyrin-Curdlan Conjugates: A Prêt-á-Porter Rather Than Haute-Couture Approach

Chemistry - A European Journal, 2017

Research paper thumbnail of Flowing microenvironments regulate the helical pitch of a semi-artificial polymer

RSC Adv., 2016

A novel strategy has been developed for tuning a polymer's conformation in a microfluidic sys... more A novel strategy has been developed for tuning a polymer's conformation in a microfluidic system. The helical pitch of a semi-artificial polymer was controlled precisely in a top-down manner under the non-equilibrium regulated in the microflow.

Research paper thumbnail of Polysaccharide-carbon nanotube complex

Research paper thumbnail of Circularly Polarized Luminescence from Supramolecular Chiral Complexes of Achiral Conjugated Polymers and a Neutral Polysaccharide

Chemistry Letters, 2010

We have developed a novel approach to the preparation of a circularly polarized luminescence mate... more We have developed a novel approach to the preparation of a circularly polarized luminescence material from a natural polysaccharide host and an achrial polythiophene guest.

Research paper thumbnail of ChemInform Abstract: Supramolecular Chemistry in Microflow Fields: Toward a New Material World of Precise Kinetic Control

Research paper thumbnail of Properly Assembled Dendrons Can Be Immobilized into Dendrimers by in situ Cross-Link

Chemistry Letters, 2000

ABSTRACT

Research paper thumbnail of Click Chemistry on Curdlan: A Regioselective and Quantitative Approach to Develop Artificial β-1,3-Glucans with Various Functional Appendages

Chemistry Letters, 2006

β-1, 3-Glucans having various functional appendages (lactoside, ferrocene, pyrene, etc.) can be p... more β-1, 3-Glucans having various functional appendages (lactoside, ferrocene, pyrene, etc.) can be prepared in an convenient, quantitative, and regioselective manner through chemo-selective [3+ 2]-cycloadditions between 6-azido-6-deoxy-curdlan and various functional ...

Research paper thumbnail of Orthogonal Polymer Recognition Based on Semiartificial Helical Polysaccharide

Chemistry Letters, 2013

ABSTRACT Two kinds of polymeric nanoarchitectures, i.e., one-dimensional polymer composites and t... more ABSTRACT Two kinds of polymeric nanoarchitectures, i.e., one-dimensional polymer composites and two-dimensional sheet-like structures, can be created using a semiartificial helical polysaccharide with one-dimensional cavities and peripheral molecular-recognition sites.

Research paper thumbnail of Semiartificial Polysaccharide Can Provide a Unique Nanospace for the Construction of Supramolecular Dye-assembly

Chemistry Letters, 2010

ABSTRACT We have revealed unique template effects of a semiartificial polysaccharide on the self-... more ABSTRACT We have revealed unique template effects of a semiartificial polysaccharide on the self-assembly of anionic cyanine dyes. The inner space of the polysaccharide acts not only as a nanotemplate for the dye assembly but also as a protective space from unfavorable photobleaching.

Research paper thumbnail of β-1,3-Glucan Schizophyllan Can Act as a One-dimensional Host to Arrange Icosahedral Carboranes

Chemistry Letters, 2007

ABSTRACT We here demonstrate that schizophyllan (SPG: one kind of beta-1, 3-glucans) /m-carborane... more ABSTRACT We here demonstrate that schizophyllan (SPG: one kind of beta-1, 3-glucans) /m-carborane nanocomposites can be easily created in a supramolecular manner by utilizing the unique wrapping capability of SPG. TEM observations revealed that incorporated in-carborane molecules adopt continuous one-dimensional (I-D) arrangement in the SPG hydrophobic cavity. We believe that the present system can provide a novel concept not only for the separation of carborane isomers and the construction of one-dimensional architectures but also for the new formulation of boron neutron capture therapy (BNCT) agents.

Research paper thumbnail of Post-polymerization of preorganized assemblies for creating shape-controlled functional materials

Chemical Society Reviews, 2007

Organic chemistry Z 0200 Post-Polymerization of Preorganized Assemblies for Creating Shape-Contro... more Organic chemistry Z 0200 Post-Polymerization of Preorganized Assemblies for Creating Shape-Controlled Functional Materials -[about 100 refs.]. -(SADA, K.; TAKEUCHI, M.; FUJITA, N.; NUMATA, M.; SHINKAI*, S.; Chem. Soc. Rev. 36 (2007) 2, 415-435; Dep. Chem. Biochem., Grad. Sch. Eng., Kyushu Univ., Fukuoka 812-81, Japan; Eng.) -Lindner 21-236

Research paper thumbnail of β-1,3-Glucan polysaccharides as novel one-dimensional hosts for DNA/RNA, conjugated polymers and nanoparticles

Chemical Communications, 2005

b-1,3-Glucan polysaccharides have triple-stranded helical structures whose sense and pitch are co... more b-1,3-Glucan polysaccharides have triple-stranded helical structures whose sense and pitch are comparable to those of polynucleotides. We recently revealed that the b-1,3-glucans could interact with certain polynucleotides to form triple-stranded and helical macromolecular complexes consisting of two polysaccharide-strands and one polynucleotide-strand. This unique property of the b-1,3-glucans has made it possible to utilize these polysaccharides as potential carriers for various functional polynucleotides. In paticular, cell-uptake efficiency of the resultant polysaccharide/polynucleotide complexes was remarkably enhanced when functional groups recognized in a biological system were introduced as pendent groups. The b-1,3-glucans can also interact with various one-dimensional architectures, such as single-walled carbon nanotubes, to produce unique nanocomposites, in which the single-walled carbon nanotubes are entrapped within the helical superstructure of b-1,3-glucans. Various conductive polymers and gold nanoparticles are also entrapped within the helical superstructure in a similar manner. In addition, diacetylene monomers entrapped within the helical superstructure can be photopolymerized to afford the corresponding poly(diacetylene)-nanofibers with a uniform diameter. These findings indicate that the b-1,3-glucans are very attractive and useful materials not only in biotechnology but also in nanotechnology. These unique properties of the b-1,3-glucans undoubtedly originate from their inherent, very strong helix-forming character which has never been observed for other polysaccharides.

Research paper thumbnail of Complementary hydrogen-bonding between thymidine-based low molecular-weight gelator and polynucleotide in organic mediaElectronic supplementary information (ESI) available: IR spectral changes in 1 gel induced by poly(A)/lipid addition; TEM images of 1 gel and 1 with poly(A)/lipid (1.0 eq.) gel, ...

Chemical Communications, 2004

We have found that aggregation mode and gelation property of thymidine-based organogelator are af... more We have found that aggregation mode and gelation property of thymidine-based organogelator are affected by the addition of its complementary polynucleotide in organic media.