Mustafa Çaycı - Academia.edu (original) (raw)

Papers by Mustafa Çaycı

Endocrine Abstracts, 2013

The Journal of Breast Health, Mar 18, 2013

Marmara Medical Journal, 2018

Radioactive iodine (RAI) treatment is recommended as the first choice for toxic thyroid nodules b... more Radioactive iodine (RAI) treatment is recommended as the first choice for toxic thyroid nodules by American Thyroid Association (ATA). Here, we present our second case of papillary thyroid carcinoma after RAI therapy. A fifty fiveyear-old woman received RAI therapy for toxic thyroid nodule in the right lobe in 2005. Pre-treatment fine needle aspiration biopsy (FNAB) revealed benign cytology. She was euthyroid after the therapy. However, 8 years after the treatment she had 15 mm thyroid nodule in the same location. This time, FNAB result was suspected for papillary thyroid carcinoma. The patient underwent bilateral total thyroidectomy and the histopathological evaluation revealed papillary thyroid carcinoma in the nodule. This is the second case with papillary carcinoma after RAI therapy. Papillary carcinoma developed after the RAI therapy. In conclusion, all cases should be closely followed up after RAI therapy for carcinoma development.

Annals of Nuclear Medicine, 2010

Clinical or subclinical hyperparathyroidism (HPT) is one of the most common endocrine disorders. ... more Clinical or subclinical hyperparathyroidism (HPT) is one of the most common endocrine disorders. In patients with HPT who meet the indications for parathyroidectomy, complete surgical resection of all hyperfunctioning parathyroid tissue is essential for the curative treatment. The conventional surgical approach is bilateral neck exploration, whereas minimally invasive parathyroidectomy has been made possible by the introduction of (99m)Tc-sestamibi scintigraphy for preoperative localization of parathyroid adenomas. In minimally invasive surgery, the surgeon expects some modalities that predict complete resection of all hyperfunctioning parathyroid glands. The prevalence rate of (99m)Tc-sestamibi scanning for single parathyroid adenoma was widely accepted as 85-95%. Moreover, the recent developing technology of semiconductor electronics has produced useful portable gamma-probes. Intraoperative navigation using these devices provides the possibility of easy and definitive identification of parathyroid nodules during the operation. In minimally invasive radioguided parathyroidectomy using gamma-probe, different protocols are based on different timing and doses of tracer injected. Each procedure is technically easy, safe, with a low morbidity rate, and has better cosmetic results and lower overall cost than conventional bilateral neck exploration. We have applied this technique in selected patients and achieved success comparable to that achieved with contemporaneously performed standard neck exploration. In the hands of a competent surgeon, the use of sestamibi scanning and radioguided parathyroidectomy in appropriately selected patients is a useful technique.

Journal of Medical Cases, 2013

Atypical parathyroid adenoma is among the tumors diagnosed difficultly and including some histolo... more Atypical parathyroid adenoma is among the tumors diagnosed difficultly and including some histological features of parathyroid carcinoma. In literature, no definite criteria have been considered to be present to distinguish atypical parathyroid adenoma preoperatively from parathyroid carcinoma. A 65-year-old woman was admitted to our clinic with complaints of arthralgia, myalgia, fatigue and loss of appetite. She had severe hypercalcemia (serum calcium 17.2 mg/dL) and hypophosphatemia (serum phosphate 1.9 mg/dL) along with an elevated intact parathyroid hormone level of 879 pg/mL. Renal functions were within normal limits. The patient was administered with intravenous hydration and diuretic treatments because of severe hypercalcemia. Six sessions of hemodialysis were performed. In neck ultrasonography, multinodular goitre was detected. Tc-99m sestamibi scintigraphy revealed a focal involvement at the middle-inferior region of left thyroid lobe. Neck magnetic resonance imagination revealed a nodular lesion in size of 22 × 14 mm at the posterior region of left thyroid lobe. Parathyroidectomy guided by intraoperative gamma probe was performed. The lesion was histopathologically consistent with atypical parathyroid adenoma. In the postoperative period, serum calcium and intact parathyroid hormone levels were decreased as levels of 7 mg/dL and 42.6 pg/mL, respectively. We reported an atypical parathyroid adenoma accompanied by severe hypercalcemia and hyperparathyroidism.

Journal of Medical Cases, 2013

Radioiodine is an important radiopharmaceutical agent in nuclear medicine practice for the treatm... more Radioiodine is an important radiopharmaceutical agent in nuclear medicine practice for the treatment of hyperthyroidism and differenciated thyroid cancer. One of the long term side effects of ionising radiation is the possibility of radiation induced malignancy. There are limited reports about malignancy after 131 I therapy for thyrotoxicosis. In this report, a case with papillary thyroid cancer after radioactive iodine (RAI) therapy for toxic thyroid nodule is presented. In this case, fine needle aspiration biopsy(FNAB) had not been done before RAI therapy and papillary carcinoma was detected four years later than the 444 MBq RAI therapy. The patient underwent bilateral total thyroidectomy and central neck dissection. After the surgery, the patient underwent 5550 MBq RAI for ablation. Summary, differentiated thyroid cancer can be found incidentally in toxic nodule or can be developed as a consequence of radioiodine therapy. FNAB must be performed for all the patients with hot or cold thyroid nodules before RAI therapy and all the patients taking RAI theraphy should be closely followed in terms of nodule growing and cancer development.

European Respiratory Journal, Sep 1, 2014

Introduction:The study was designed to determine the relationship between survival time and maxim... more Introduction:The study was designed to determine the relationship between survival time and maximum Standard Uptake Value (SUVmax), mean Standard Uptake Value (mSUV) and Metabolic Tumor Volume (MTV) of fluorodeoxyglucose-positron emission tomography/computed tomography (FDG-PET/CT) in patients with non-small cell lung cancer (NSCLC), and examine the impact of clinical and radiological data of these patients on survival. Material and Methods: We performed a retrospective analysis of the files of 79 patients with NSCLC who presented to our hospital, received a final diagnosis and underwent FDG-PET/CT for staging. Clinical, radiological and FDG-PET/CT parameters with an impact on prognosis such as the SUVmax of the primary tumor, calculated by the volumetric region of interest in the FDG/PET/CT scans during initial diagnosis, the mean SUV of the tumor, and metabolic tumor volume (MTV), obtained with a threshold of SUVmax > 2.5 were recorded and statistically analysed. Results: According to the Cox regression analysis, higher MTV (RR: 1.006, p=0.03) and mSUV (RR:1.302, p=0.03) had a significant impact on shortening of the mean survival time. However, no statistical significance was achieved for SUVmax measurements (RR:0.970, p=0,39). Furthermore, there was a significant relationship between increased tumor size ( Conclusion:We believe that we might have more accurate information about survival time of our patients if we also evaluate mSUV and MTV in combination with SUVmax, which is frequently used for diagnosis and monitoring of patients with NSCLC during our daily practice.

World Journal of Pediatrics, 2015

Background: The effects of Helicobacter pylori (H. pylori) infection on growth are a controversia... more Background: The effects of Helicobacter pylori (H. pylori) infection on growth are a controversial issue. We investigated the effects of long-term H. pylori infection on height and weight in children. Methods: A total of 200 children of 7-18 years old suffering from dyspeptic complaints were classified into two groups: H. pylori positive and negative groups, respectively. Whether the infection was impoved was followed up while performing urea breath test, and according to exposure time to the infection, the children were further divided into group 1 (≤1.5 months), group 2 (>1.5-≤6 months) and group 3 (>6 months). Antropometric measurements were obtained and repeated every six months. Results: Mean growth velocity scores in the H. pylori positive and negative groups were 0.49±3.85 [95% confidence interval (CI):-0.21-1.18] and 1.98±4.42 (95% CI: 1-2.96), respectively. The difference between both groups was statistically significant (P=0.012). Mean growth velocity scores in groups 1, 2 and 3 were 0.96±3.84, 0.16±4.51 and-0.85±3.09, respectively. Mean growth velocity scores of group 3 were significantly lower than those of groups 0 and 1 (P=0.005 and P=0.041). The mean weight scores in group 3 were similar to those in group 2, but the scores in group 3 were signifi cantly lower than those in group 1 (-1.75±1.05,-1.21±1.37 and-0.88±1.49, respectively). Conclusion: As the duration of exposure is prolonged in children with H. pylori infection, the negative effect of the infection on both height and weight is evident.

Turkish Journal of Surgery, 2011

Primer hiperparatiroidi (pHPT) tanısı serum kalsiyum yüksekliği ile beraber uygunsuz parathormon ... more Primer hiperparatiroidi (pHPT) tanısı serum kalsiyum yüksekliği ile beraber uygunsuz parathormon (PTH) yüksekliği ile konur. pHPT olguları semptomatik ve asemptomatik olabilir. Semptomatik pHPT'nin ve medikal tedaviye cevap vermeyen sekonder hiperparatiroidizmin tedavisi cerrahidir. Asemptomatik pHPT'nin ameliyat endikasyonları 2002 Konsensus Toplantısı'nda yeniden düzenlenmiştir (1). pHPT li hastalarda paratiroidektomi ile biyokimyasal değerler normalleşir, kemik mineral yoğunluğu artar. Ameliyat edilmeyen pHPT hastalarının yaklaşık dörtte birinde hastalık ilerler (2). pHPT de minimal invazif de yapılabilen cerrahi tedavi yaşam kalitesinde iyileşme sağlar (3). Yurdumuzda pHPT henüz yeterince dikkat çekmeyen bir hastalık olup hastaların tanısı nadiren asemptomatik evrede konabilmektedir (4). Son on yılda Hastanemizde paratiroid cerrahisinin gelişim sürecini ve bu sürece etkili faktörleri ve minimal invazif paratiroidektomide (MİP) lokal infiltrasyon anestezinin yerini belirlemek amacı ile bu çalışmayı yaptık. HASTALAR VE METOD Kasım 2000 ile Kasım 2010 arasında geçen 10 yılda Hastanemizde yapılan paratiroid ameliyatları ile ilgili kayıtlar retrospektif olarak ameliyat defterleri, hasta dosyaları ve bilgisayarlardan incelendi. Ayrıca paratiroid hastalarının tanı ve tedavisine etkili olabileceği düşünülen faktörlerden çalışan cerrahların paratiroid cerrahisi deneyimleri ve bu alana ilgileri, hastanede endokrinoloji, nefroloji ve nükleer tıp, endokrin cerrahide deneyimli genel cerrahi uzmanlarının hizmete başlama, parathormon, kan kalsiyumu, sintigrafi tetkiklerinin yapılmaya başlama tarihleri belirlendi.

Journal of Medical Cases, 2013

High parathormone (iPTH) values in the patients having parathyroid autotransplantations can be de... more High parathormone (iPTH) values in the patients having parathyroid autotransplantations can be derived from parathyromatosis or preanalytical differences. In this report, we presented a patient with kidney failure and factitiously high iPTH levels. Because of tertiary hyperparathyroidism, total parathyroidectomy and 1/2 parathyroid tissue autotransplantation to brachioradial muscle in right forearm operation has been performed. Although he has been followed with high iPTH levels for a long time, he does not have parathyromatosis. iPTH level was found normal when blood samples were taken from the other arm. High iPTH levels are thought to be related to the place where the blood samples taken i.e., samples taken from the proximal region of autotransplantation, we recommend the blood sample should be taken from the contralateral or distal region of the autotransplantation in order to avoid misdiagnosis and unnecessary and incorrect procedures in patients with parathyroid autotransplantation.

Case Reports in Pulmonology, 2015

Chylothorax is characterized by fluid accumulation in the pleural cavity containing chylomicrons ... more Chylothorax is characterized by fluid accumulation in the pleural cavity containing chylomicrons due to disruption of lymphatic drainage in the thoracic ductus and development of chylothorax. A 60-year-old male patient presented to our clinic with shortness of breath and displayed bilateral pleural effusion and diffuse mediastinal lymph nodes in his computed chest tomography images. There were no thickening and nodular formation on the pleural surfaces. PET-CT showed no pathological FDG uptake. Thoracentesis showed a chylous effusion. Drainage reduced during monitoring could not be stopped; therefore, surgical intervention was considered. The patient underwent right thoracotomy. There were no pathological findings in the parietal and visceral pleura during the surgery. Initially lymphoma was considered. Perioperative samples were collected from the mediastinal lymph node. The pathology analysis reported metastasis of malignant mesothelioma. Evaluation of a repeated chest computed to...

Clinical nuclear medicine, Jan 4, 2015

The study was designed to determine the relationship between survival time of standardized uptake... more The study was designed to determine the relationship between survival time of standardized uptake value (SUVmax and SUVmean) and metabolic tumor volume (MTV) in patients with non-small cell lung cancer (NSCLC), and examine the impact of demographic, clinical, and radiological data of these patients on survival. We performed a retrospective analysis of the records of 79 patients with NSCLC who presented to our hospital between May 2010 and March 2013, received a final diagnosis, and underwent F-FDG PET/CT for staging. Clinical, radiological, and F-FDG PET/CT parameters with an impact on prognosis such as the SUVmax of the primary tumor as calculated by the volumetric region of interest in the F-FDG PET/CT scans during initial diagnosis, mean SUV of the tumor, and MTV obtained with a threshold of SUVmax greater than 2.5 were recorded and statistically analyzed. A statistical analysis was carried out based on the clinical, radiological, and PET/CT findings of the patients who were divi...

Endocrine Abstracts, 2013

The Journal of Breast Health, Mar 18, 2013

Marmara Medical Journal, 2018

Radioactive iodine (RAI) treatment is recommended as the first choice for toxic thyroid nodules b... more Radioactive iodine (RAI) treatment is recommended as the first choice for toxic thyroid nodules by American Thyroid Association (ATA). Here, we present our second case of papillary thyroid carcinoma after RAI therapy. A fifty fiveyear-old woman received RAI therapy for toxic thyroid nodule in the right lobe in 2005. Pre-treatment fine needle aspiration biopsy (FNAB) revealed benign cytology. She was euthyroid after the therapy. However, 8 years after the treatment she had 15 mm thyroid nodule in the same location. This time, FNAB result was suspected for papillary thyroid carcinoma. The patient underwent bilateral total thyroidectomy and the histopathological evaluation revealed papillary thyroid carcinoma in the nodule. This is the second case with papillary carcinoma after RAI therapy. Papillary carcinoma developed after the RAI therapy. In conclusion, all cases should be closely followed up after RAI therapy for carcinoma development.

Annals of Nuclear Medicine, 2010

Clinical or subclinical hyperparathyroidism (HPT) is one of the most common endocrine disorders. ... more Clinical or subclinical hyperparathyroidism (HPT) is one of the most common endocrine disorders. In patients with HPT who meet the indications for parathyroidectomy, complete surgical resection of all hyperfunctioning parathyroid tissue is essential for the curative treatment. The conventional surgical approach is bilateral neck exploration, whereas minimally invasive parathyroidectomy has been made possible by the introduction of (99m)Tc-sestamibi scintigraphy for preoperative localization of parathyroid adenomas. In minimally invasive surgery, the surgeon expects some modalities that predict complete resection of all hyperfunctioning parathyroid glands. The prevalence rate of (99m)Tc-sestamibi scanning for single parathyroid adenoma was widely accepted as 85-95%. Moreover, the recent developing technology of semiconductor electronics has produced useful portable gamma-probes. Intraoperative navigation using these devices provides the possibility of easy and definitive identification of parathyroid nodules during the operation. In minimally invasive radioguided parathyroidectomy using gamma-probe, different protocols are based on different timing and doses of tracer injected. Each procedure is technically easy, safe, with a low morbidity rate, and has better cosmetic results and lower overall cost than conventional bilateral neck exploration. We have applied this technique in selected patients and achieved success comparable to that achieved with contemporaneously performed standard neck exploration. In the hands of a competent surgeon, the use of sestamibi scanning and radioguided parathyroidectomy in appropriately selected patients is a useful technique.

Journal of Medical Cases, 2013

Atypical parathyroid adenoma is among the tumors diagnosed difficultly and including some histolo... more Atypical parathyroid adenoma is among the tumors diagnosed difficultly and including some histological features of parathyroid carcinoma. In literature, no definite criteria have been considered to be present to distinguish atypical parathyroid adenoma preoperatively from parathyroid carcinoma. A 65-year-old woman was admitted to our clinic with complaints of arthralgia, myalgia, fatigue and loss of appetite. She had severe hypercalcemia (serum calcium 17.2 mg/dL) and hypophosphatemia (serum phosphate 1.9 mg/dL) along with an elevated intact parathyroid hormone level of 879 pg/mL. Renal functions were within normal limits. The patient was administered with intravenous hydration and diuretic treatments because of severe hypercalcemia. Six sessions of hemodialysis were performed. In neck ultrasonography, multinodular goitre was detected. Tc-99m sestamibi scintigraphy revealed a focal involvement at the middle-inferior region of left thyroid lobe. Neck magnetic resonance imagination revealed a nodular lesion in size of 22 × 14 mm at the posterior region of left thyroid lobe. Parathyroidectomy guided by intraoperative gamma probe was performed. The lesion was histopathologically consistent with atypical parathyroid adenoma. In the postoperative period, serum calcium and intact parathyroid hormone levels were decreased as levels of 7 mg/dL and 42.6 pg/mL, respectively. We reported an atypical parathyroid adenoma accompanied by severe hypercalcemia and hyperparathyroidism.

Journal of Medical Cases, 2013

Radioiodine is an important radiopharmaceutical agent in nuclear medicine practice for the treatm... more Radioiodine is an important radiopharmaceutical agent in nuclear medicine practice for the treatment of hyperthyroidism and differenciated thyroid cancer. One of the long term side effects of ionising radiation is the possibility of radiation induced malignancy. There are limited reports about malignancy after 131 I therapy for thyrotoxicosis. In this report, a case with papillary thyroid cancer after radioactive iodine (RAI) therapy for toxic thyroid nodule is presented. In this case, fine needle aspiration biopsy(FNAB) had not been done before RAI therapy and papillary carcinoma was detected four years later than the 444 MBq RAI therapy. The patient underwent bilateral total thyroidectomy and central neck dissection. After the surgery, the patient underwent 5550 MBq RAI for ablation. Summary, differentiated thyroid cancer can be found incidentally in toxic nodule or can be developed as a consequence of radioiodine therapy. FNAB must be performed for all the patients with hot or cold thyroid nodules before RAI therapy and all the patients taking RAI theraphy should be closely followed in terms of nodule growing and cancer development.

European Respiratory Journal, Sep 1, 2014

Introduction:The study was designed to determine the relationship between survival time and maxim... more Introduction:The study was designed to determine the relationship between survival time and maximum Standard Uptake Value (SUVmax), mean Standard Uptake Value (mSUV) and Metabolic Tumor Volume (MTV) of fluorodeoxyglucose-positron emission tomography/computed tomography (FDG-PET/CT) in patients with non-small cell lung cancer (NSCLC), and examine the impact of clinical and radiological data of these patients on survival. Material and Methods: We performed a retrospective analysis of the files of 79 patients with NSCLC who presented to our hospital, received a final diagnosis and underwent FDG-PET/CT for staging. Clinical, radiological and FDG-PET/CT parameters with an impact on prognosis such as the SUVmax of the primary tumor, calculated by the volumetric region of interest in the FDG/PET/CT scans during initial diagnosis, the mean SUV of the tumor, and metabolic tumor volume (MTV), obtained with a threshold of SUVmax > 2.5 were recorded and statistically analysed. Results: According to the Cox regression analysis, higher MTV (RR: 1.006, p=0.03) and mSUV (RR:1.302, p=0.03) had a significant impact on shortening of the mean survival time. However, no statistical significance was achieved for SUVmax measurements (RR:0.970, p=0,39). Furthermore, there was a significant relationship between increased tumor size ( Conclusion:We believe that we might have more accurate information about survival time of our patients if we also evaluate mSUV and MTV in combination with SUVmax, which is frequently used for diagnosis and monitoring of patients with NSCLC during our daily practice.

World Journal of Pediatrics, 2015

Background: The effects of Helicobacter pylori (H. pylori) infection on growth are a controversia... more Background: The effects of Helicobacter pylori (H. pylori) infection on growth are a controversial issue. We investigated the effects of long-term H. pylori infection on height and weight in children. Methods: A total of 200 children of 7-18 years old suffering from dyspeptic complaints were classified into two groups: H. pylori positive and negative groups, respectively. Whether the infection was impoved was followed up while performing urea breath test, and according to exposure time to the infection, the children were further divided into group 1 (≤1.5 months), group 2 (>1.5-≤6 months) and group 3 (>6 months). Antropometric measurements were obtained and repeated every six months. Results: Mean growth velocity scores in the H. pylori positive and negative groups were 0.49±3.85 [95% confidence interval (CI):-0.21-1.18] and 1.98±4.42 (95% CI: 1-2.96), respectively. The difference between both groups was statistically significant (P=0.012). Mean growth velocity scores in groups 1, 2 and 3 were 0.96±3.84, 0.16±4.51 and-0.85±3.09, respectively. Mean growth velocity scores of group 3 were significantly lower than those of groups 0 and 1 (P=0.005 and P=0.041). The mean weight scores in group 3 were similar to those in group 2, but the scores in group 3 were signifi cantly lower than those in group 1 (-1.75±1.05,-1.21±1.37 and-0.88±1.49, respectively). Conclusion: As the duration of exposure is prolonged in children with H. pylori infection, the negative effect of the infection on both height and weight is evident.

Turkish Journal of Surgery, 2011

Primer hiperparatiroidi (pHPT) tanısı serum kalsiyum yüksekliği ile beraber uygunsuz parathormon ... more Primer hiperparatiroidi (pHPT) tanısı serum kalsiyum yüksekliği ile beraber uygunsuz parathormon (PTH) yüksekliği ile konur. pHPT olguları semptomatik ve asemptomatik olabilir. Semptomatik pHPT'nin ve medikal tedaviye cevap vermeyen sekonder hiperparatiroidizmin tedavisi cerrahidir. Asemptomatik pHPT'nin ameliyat endikasyonları 2002 Konsensus Toplantısı'nda yeniden düzenlenmiştir (1). pHPT li hastalarda paratiroidektomi ile biyokimyasal değerler normalleşir, kemik mineral yoğunluğu artar. Ameliyat edilmeyen pHPT hastalarının yaklaşık dörtte birinde hastalık ilerler (2). pHPT de minimal invazif de yapılabilen cerrahi tedavi yaşam kalitesinde iyileşme sağlar (3). Yurdumuzda pHPT henüz yeterince dikkat çekmeyen bir hastalık olup hastaların tanısı nadiren asemptomatik evrede konabilmektedir (4). Son on yılda Hastanemizde paratiroid cerrahisinin gelişim sürecini ve bu sürece etkili faktörleri ve minimal invazif paratiroidektomide (MİP) lokal infiltrasyon anestezinin yerini belirlemek amacı ile bu çalışmayı yaptık. HASTALAR VE METOD Kasım 2000 ile Kasım 2010 arasında geçen 10 yılda Hastanemizde yapılan paratiroid ameliyatları ile ilgili kayıtlar retrospektif olarak ameliyat defterleri, hasta dosyaları ve bilgisayarlardan incelendi. Ayrıca paratiroid hastalarının tanı ve tedavisine etkili olabileceği düşünülen faktörlerden çalışan cerrahların paratiroid cerrahisi deneyimleri ve bu alana ilgileri, hastanede endokrinoloji, nefroloji ve nükleer tıp, endokrin cerrahide deneyimli genel cerrahi uzmanlarının hizmete başlama, parathormon, kan kalsiyumu, sintigrafi tetkiklerinin yapılmaya başlama tarihleri belirlendi.

Journal of Medical Cases, 2013

High parathormone (iPTH) values in the patients having parathyroid autotransplantations can be de... more High parathormone (iPTH) values in the patients having parathyroid autotransplantations can be derived from parathyromatosis or preanalytical differences. In this report, we presented a patient with kidney failure and factitiously high iPTH levels. Because of tertiary hyperparathyroidism, total parathyroidectomy and 1/2 parathyroid tissue autotransplantation to brachioradial muscle in right forearm operation has been performed. Although he has been followed with high iPTH levels for a long time, he does not have parathyromatosis. iPTH level was found normal when blood samples were taken from the other arm. High iPTH levels are thought to be related to the place where the blood samples taken i.e., samples taken from the proximal region of autotransplantation, we recommend the blood sample should be taken from the contralateral or distal region of the autotransplantation in order to avoid misdiagnosis and unnecessary and incorrect procedures in patients with parathyroid autotransplantation.

Case Reports in Pulmonology, 2015

Chylothorax is characterized by fluid accumulation in the pleural cavity containing chylomicrons ... more Chylothorax is characterized by fluid accumulation in the pleural cavity containing chylomicrons due to disruption of lymphatic drainage in the thoracic ductus and development of chylothorax. A 60-year-old male patient presented to our clinic with shortness of breath and displayed bilateral pleural effusion and diffuse mediastinal lymph nodes in his computed chest tomography images. There were no thickening and nodular formation on the pleural surfaces. PET-CT showed no pathological FDG uptake. Thoracentesis showed a chylous effusion. Drainage reduced during monitoring could not be stopped; therefore, surgical intervention was considered. The patient underwent right thoracotomy. There were no pathological findings in the parietal and visceral pleura during the surgery. Initially lymphoma was considered. Perioperative samples were collected from the mediastinal lymph node. The pathology analysis reported metastasis of malignant mesothelioma. Evaluation of a repeated chest computed to...

Clinical nuclear medicine, Jan 4, 2015

The study was designed to determine the relationship between survival time of standardized uptake... more The study was designed to determine the relationship between survival time of standardized uptake value (SUVmax and SUVmean) and metabolic tumor volume (MTV) in patients with non-small cell lung cancer (NSCLC), and examine the impact of demographic, clinical, and radiological data of these patients on survival. We performed a retrospective analysis of the records of 79 patients with NSCLC who presented to our hospital between May 2010 and March 2013, received a final diagnosis, and underwent F-FDG PET/CT for staging. Clinical, radiological, and F-FDG PET/CT parameters with an impact on prognosis such as the SUVmax of the primary tumor as calculated by the volumetric region of interest in the F-FDG PET/CT scans during initial diagnosis, mean SUV of the tumor, and MTV obtained with a threshold of SUVmax greater than 2.5 were recorded and statistically analyzed. A statistical analysis was carried out based on the clinical, radiological, and PET/CT findings of the patients who were divi...