Mustafa Senol - Academia.edu (original) (raw)
Papers by Mustafa Senol
Annals of medical research, 1997
PubMed, Feb 1, 1999
Patients with an unpleasant body odor often consult dermatologists. A dermatologist needs to beco... more Patients with an unpleasant body odor often consult dermatologists. A dermatologist needs to become familiar with the occurrence and significance of medically related odors. Although body odor may be essentially physiological, and problems with body mal-odor are paid little attention, they can cause many personal troubles and may induce a variety of psychosocial disturbances. Body odor in general is an indicator of individual care and hygiene, or results from eating garlic, onion, spicy foods, curry, or drinking alcohol; however, in some instances it can be pathologic. It is a well-known clinical fact that many diseases (both of internal and cutaneous origin), several syndromes, and some intoxications cause characteristic, peculiar, and identifiable odors. Their identification can provide diagnostic clues, guide the laboratory evaluation, and help in the choice of immediate and appropriate therapy. Thus, olfactory evaluation can be an important part of clinical examination and olfactory diagnosis is still valid in recognizing certain diseases. This report reviews the physiological and pathologic body odors and the importance of olfactory diagnosis in dermatology.
Turgut Ozal Tıp Merkezi Dergisi, 1995
The HAIR-AN Syndrome affects about 5% of hirsute women and characterized by insulin resistance, e... more The HAIR-AN Syndrome affects about 5% of hirsute women and characterized by insulin resistance, elevated insulin levels, acanthosis nigricans(AN) and hyperandrogenism. The patient presented here is a 21 year-old woman who has secondary amenorrhea, hirsutism, and hyperpigmented skin changes. The patient was given oral contraceptive and spironolactone. After nine months, the patient was observed for significant clinical and hormonal improvement. [Journal of Turgut Ozal Medical Center 2(2):204-205,1995] Key words: Acantosis nigricans, hirsutismus, insulin resistance ,oral contraceptive, spironolactone
Journal of the European Academy of Dermatology and Venereology, 2002
Background The exact aetiology of recurrent aphthous stomatitis (RAS) is still unknown, but diffe... more Background The exact aetiology of recurrent aphthous stomatitis (RAS) is still unknown, but different predisposing factors, including iron, vitamin B12 and folic acid deficiencies, have been proposed.Material and methods Serum iron, ferritin, folic acid and vitamin B12 levels were investigated in 35 patients with RAS and in 26 healthy controls.Results Vitamin B12 levels were found significantly lower in subjects with RAS than in controls. No significant differences were found in other parameters.Conclusion We concluded that vitamin B12 deficiency may be an aetiological factor in recurrent aphthous stomatitis.
Turkiye Klinikleri J …, 2005
... Mekanizmaları Dr. Mustafa ŞENOL a a Dermatoloji AD, İnönü Üniversitesi Tıp Fakültesi, MALATYA... more ... Mekanizmaları Dr. Mustafa ŞENOL a a Dermatoloji AD, İnönü Üniversitesi Tıp Fakültesi, MALATYA. Kandida albikans, genellikle gastrointestinal sistem ve solunum yolları mukozası, kadın alt genital sistemleri ve derinin katlantı yerlerinde bulunan fırsatçı bir maya türüdür. ...
Journal of Inonu …, 2010
The activity of natural killer (NK) cells of peripheral stem cell (PSC) products from 24 patients... more The activity of natural killer (NK) cells of peripheral stem cell (PSC) products from 24 patients with non-Hodgkin's lymphoma (NHL) were examined both before and following 5 days co-incubation with IL-2. This study showed that the PSC products prior to IL-2 incubation had higher NK ...
Clinical Drug Investigation, 2005
Embolia cutis medicamentosa (ECM) [Nicolau severe pain and a bluish discoloration soon after the ... more Embolia cutis medicamentosa (ECM) [Nicolau severe pain and a bluish discoloration soon after the syndrome, livedo-like dermatitis] was first de-injection. One week later, an oozing ulcer with a scribed in 1925 by Nicolau in a patient receiving black crust developed. She had had similar IM injectreatment with bismuth for syphilis. The pathogene-tions several times previously, but this was the first sis of this rare phenomenon is thought to be acute time she had experienced this complication. arterial thrombosis occurring immediately after in-Dermatological examination revealed an approxtravascular injection of an insoluble agent. It starts imately 5 × 3cm, well demarcated and purulent ulas a well demarcated and livedo-like plaque at an cer surrounded by livedoid margins on the lateral intramuscular (IM) or subcutaneous (SC) injection side of the right gluteal region (figure 1). The patient site. Frequently, there is a haemorrhagic blister at was otherwise healthy. Routine laboratory tests the centre of the lesion following a superficial or were within normal limits except for a white blood deep ulcer that may penetrate deep into the subcutacell (WBC) count of 11 200/mm 3 and an erythrocyte neous fat and muscle. Secondary bacterial infecsedimentation rate (ESR) of 21 mm/h. Chest and tions, nerve injury, healing with scar formation and gluteal region x-rays yielded no abnormalities. A decrease in muscle function may be further complipurified protein derivative (PDD) test for tuberculocations. [1,2] sis was negative. Smears from the ulcer showed no We present here two distinct cases of Nicolau fungi or acid-fast microorganisms. Microbiological syndrome occurring in an adult and a child followcultures yielded Staphylococcus aureus. An inciing IM diclofenac and SC interferon beta (IFNβ)-1a injections, respectively. Case Reports Case 1 A 34-year-old woman presented with a painful ulcer on her right buttock at the IM injection site of diclofenac sodium (Voltaren ® , Novartis Pharma AG, Basel, Switzerland) 1 administered 2 months previously. The patient said she had experienced Fig. 1. Case 1: deep ulceration in the gluteal region. (Nicolau syndrome) due to triple vaccine (DTP) injection. Br J Dermatol 1997; 137: 1030-1 men is the preferred site. However, no matter how good the injection technique is, it is not possible to
Medical Teacher, 2006
View related articles Citing articles: 1 View citing articles Like Ker et al. (2005) we are commi... more View related articles Citing articles: 1 View citing articles Like Ker et al. (2005) we are committed to sharing experiences in order to develop simulated patient programmes that provide learners with the best opportunities in which to develop a whole range of professional skills. We believe the success of our simulated patient programme is based on adherence to principles of adult learning (Knowles, 1990), thinking creatively about ways to support health care professional training and a team approach that whenever possible includes students, actors, clinicians, psychologists and educationalists at all stages of programme development, implementation and evaluation.
Turgut Özal Tıp Merkezi Dergisi, 1994
The conventional methods for the laboratory diagnosis of tuberculosis and other mycobacterial dis... more The conventional methods for the laboratory diagnosis of tuberculosis and other mycobacterial diseases are time consuming and beyond the sco/ge of most of the small and medium-sized hospital facilities. Therefore, there has been considerable interest in the development of a serological method for the detection of antibodies against myobactena. The humoral immune response occuring during mycobacterial infections can be detected with some serological tests (R.I.A, T'.I.ISA. latex agglutination,etc). In this paper, humoral immunity changes in tuberculosis and serological diagnostic procedures are reviewed.Journal oJ'Turgut Ozal Medical ('enter 1(4):324-333.1994/ Key Words. Mycobacterial infections, antigen 60. tuberculosis, serology
Annals of medical research, 1997
In this study, primary and secondary school students were screened for the presence of viral infe... more In this study, primary and secondary school students were screened for the presence of viral infections of the skin in Malatya. Among 9281 students, 210 had warts, 14 had herpes simplex, 3 had molloscum contagiosum, 2 had zona, and 1 had varicella. The viral infection rates were calculated as 2.26%, 0.15%, 0.032%, 0.021%, and 0.011% respectively. [Journal of Turgut Ozal Medical Center 1997;4(4):387-390] Key words: Cutaneous viral infections, school children, epidemiology
A 30-year-old mechanical engineer suffering multiple asymtomatic papules on his face, especially ... more A 30-year-old mechanical engineer suffering multiple asymtomatic papules on his face, especially around the nose was diagnosed as tuberous sclerosis. He had also Shagreen patches on his lumbosacral region, periungual fibromas on his toes. He had no history of seizure although there were small periventricular calcifications on cranial CT. We could not find any other features of tuberous sclerosis. The case was presented because of the patient’s normal mental status and literature on this issue was reviewed. [Journal of Turgut Ozal Medical Center 1996;3(3):206-209]
Tropical biomedicine, 2010
Cutaneous tuberculosis, a rare form of extrapulmonary tuberculosis, has a wide variety of clinica... more Cutaneous tuberculosis, a rare form of extrapulmonary tuberculosis, has a wide variety of clinical presentations and continues to be one of the most important dermatological diseases in developing countries.The sites of predilection are neck, supraclavicular region, axilla, and groin. Single or multiple cutaneous and subcutaneous nodules first appear and breakdown later resulting in undermined ulcers with a purulent discharge, sinuses, and disfiguring scars. We report a multifocal case of scrofuloderma in a 47-year-old immunocompetent man treated successfully with four antituberculotic drugs, albeit lately due to the loss of awareness to the disease.
Annals of medical research, 1996
Annals of medical research, 1995
Annals of medical research, 1994
Annals of medical research, 1994
Annals of medical research, 1997
PubMed, Feb 1, 1999
Patients with an unpleasant body odor often consult dermatologists. A dermatologist needs to beco... more Patients with an unpleasant body odor often consult dermatologists. A dermatologist needs to become familiar with the occurrence and significance of medically related odors. Although body odor may be essentially physiological, and problems with body mal-odor are paid little attention, they can cause many personal troubles and may induce a variety of psychosocial disturbances. Body odor in general is an indicator of individual care and hygiene, or results from eating garlic, onion, spicy foods, curry, or drinking alcohol; however, in some instances it can be pathologic. It is a well-known clinical fact that many diseases (both of internal and cutaneous origin), several syndromes, and some intoxications cause characteristic, peculiar, and identifiable odors. Their identification can provide diagnostic clues, guide the laboratory evaluation, and help in the choice of immediate and appropriate therapy. Thus, olfactory evaluation can be an important part of clinical examination and olfactory diagnosis is still valid in recognizing certain diseases. This report reviews the physiological and pathologic body odors and the importance of olfactory diagnosis in dermatology.
Turgut Ozal Tıp Merkezi Dergisi, 1995
The HAIR-AN Syndrome affects about 5% of hirsute women and characterized by insulin resistance, e... more The HAIR-AN Syndrome affects about 5% of hirsute women and characterized by insulin resistance, elevated insulin levels, acanthosis nigricans(AN) and hyperandrogenism. The patient presented here is a 21 year-old woman who has secondary amenorrhea, hirsutism, and hyperpigmented skin changes. The patient was given oral contraceptive and spironolactone. After nine months, the patient was observed for significant clinical and hormonal improvement. [Journal of Turgut Ozal Medical Center 2(2):204-205,1995] Key words: Acantosis nigricans, hirsutismus, insulin resistance ,oral contraceptive, spironolactone
Journal of the European Academy of Dermatology and Venereology, 2002
Background The exact aetiology of recurrent aphthous stomatitis (RAS) is still unknown, but diffe... more Background The exact aetiology of recurrent aphthous stomatitis (RAS) is still unknown, but different predisposing factors, including iron, vitamin B12 and folic acid deficiencies, have been proposed.Material and methods Serum iron, ferritin, folic acid and vitamin B12 levels were investigated in 35 patients with RAS and in 26 healthy controls.Results Vitamin B12 levels were found significantly lower in subjects with RAS than in controls. No significant differences were found in other parameters.Conclusion We concluded that vitamin B12 deficiency may be an aetiological factor in recurrent aphthous stomatitis.
Turkiye Klinikleri J …, 2005
... Mekanizmaları Dr. Mustafa ŞENOL a a Dermatoloji AD, İnönü Üniversitesi Tıp Fakültesi, MALATYA... more ... Mekanizmaları Dr. Mustafa ŞENOL a a Dermatoloji AD, İnönü Üniversitesi Tıp Fakültesi, MALATYA. Kandida albikans, genellikle gastrointestinal sistem ve solunum yolları mukozası, kadın alt genital sistemleri ve derinin katlantı yerlerinde bulunan fırsatçı bir maya türüdür. ...
Journal of Inonu …, 2010
The activity of natural killer (NK) cells of peripheral stem cell (PSC) products from 24 patients... more The activity of natural killer (NK) cells of peripheral stem cell (PSC) products from 24 patients with non-Hodgkin's lymphoma (NHL) were examined both before and following 5 days co-incubation with IL-2. This study showed that the PSC products prior to IL-2 incubation had higher NK ...
Clinical Drug Investigation, 2005
Embolia cutis medicamentosa (ECM) [Nicolau severe pain and a bluish discoloration soon after the ... more Embolia cutis medicamentosa (ECM) [Nicolau severe pain and a bluish discoloration soon after the syndrome, livedo-like dermatitis] was first de-injection. One week later, an oozing ulcer with a scribed in 1925 by Nicolau in a patient receiving black crust developed. She had had similar IM injectreatment with bismuth for syphilis. The pathogene-tions several times previously, but this was the first sis of this rare phenomenon is thought to be acute time she had experienced this complication. arterial thrombosis occurring immediately after in-Dermatological examination revealed an approxtravascular injection of an insoluble agent. It starts imately 5 × 3cm, well demarcated and purulent ulas a well demarcated and livedo-like plaque at an cer surrounded by livedoid margins on the lateral intramuscular (IM) or subcutaneous (SC) injection side of the right gluteal region (figure 1). The patient site. Frequently, there is a haemorrhagic blister at was otherwise healthy. Routine laboratory tests the centre of the lesion following a superficial or were within normal limits except for a white blood deep ulcer that may penetrate deep into the subcutacell (WBC) count of 11 200/mm 3 and an erythrocyte neous fat and muscle. Secondary bacterial infecsedimentation rate (ESR) of 21 mm/h. Chest and tions, nerve injury, healing with scar formation and gluteal region x-rays yielded no abnormalities. A decrease in muscle function may be further complipurified protein derivative (PDD) test for tuberculocations. [1,2] sis was negative. Smears from the ulcer showed no We present here two distinct cases of Nicolau fungi or acid-fast microorganisms. Microbiological syndrome occurring in an adult and a child followcultures yielded Staphylococcus aureus. An inciing IM diclofenac and SC interferon beta (IFNβ)-1a injections, respectively. Case Reports Case 1 A 34-year-old woman presented with a painful ulcer on her right buttock at the IM injection site of diclofenac sodium (Voltaren ® , Novartis Pharma AG, Basel, Switzerland) 1 administered 2 months previously. The patient said she had experienced Fig. 1. Case 1: deep ulceration in the gluteal region. (Nicolau syndrome) due to triple vaccine (DTP) injection. Br J Dermatol 1997; 137: 1030-1 men is the preferred site. However, no matter how good the injection technique is, it is not possible to
Medical Teacher, 2006
View related articles Citing articles: 1 View citing articles Like Ker et al. (2005) we are commi... more View related articles Citing articles: 1 View citing articles Like Ker et al. (2005) we are committed to sharing experiences in order to develop simulated patient programmes that provide learners with the best opportunities in which to develop a whole range of professional skills. We believe the success of our simulated patient programme is based on adherence to principles of adult learning (Knowles, 1990), thinking creatively about ways to support health care professional training and a team approach that whenever possible includes students, actors, clinicians, psychologists and educationalists at all stages of programme development, implementation and evaluation.
Turgut Özal Tıp Merkezi Dergisi, 1994
The conventional methods for the laboratory diagnosis of tuberculosis and other mycobacterial dis... more The conventional methods for the laboratory diagnosis of tuberculosis and other mycobacterial diseases are time consuming and beyond the sco/ge of most of the small and medium-sized hospital facilities. Therefore, there has been considerable interest in the development of a serological method for the detection of antibodies against myobactena. The humoral immune response occuring during mycobacterial infections can be detected with some serological tests (R.I.A, T'.I.ISA. latex agglutination,etc). In this paper, humoral immunity changes in tuberculosis and serological diagnostic procedures are reviewed.Journal oJ'Turgut Ozal Medical ('enter 1(4):324-333.1994/ Key Words. Mycobacterial infections, antigen 60. tuberculosis, serology
Annals of medical research, 1997
In this study, primary and secondary school students were screened for the presence of viral infe... more In this study, primary and secondary school students were screened for the presence of viral infections of the skin in Malatya. Among 9281 students, 210 had warts, 14 had herpes simplex, 3 had molloscum contagiosum, 2 had zona, and 1 had varicella. The viral infection rates were calculated as 2.26%, 0.15%, 0.032%, 0.021%, and 0.011% respectively. [Journal of Turgut Ozal Medical Center 1997;4(4):387-390] Key words: Cutaneous viral infections, school children, epidemiology
A 30-year-old mechanical engineer suffering multiple asymtomatic papules on his face, especially ... more A 30-year-old mechanical engineer suffering multiple asymtomatic papules on his face, especially around the nose was diagnosed as tuberous sclerosis. He had also Shagreen patches on his lumbosacral region, periungual fibromas on his toes. He had no history of seizure although there were small periventricular calcifications on cranial CT. We could not find any other features of tuberous sclerosis. The case was presented because of the patient’s normal mental status and literature on this issue was reviewed. [Journal of Turgut Ozal Medical Center 1996;3(3):206-209]
Tropical biomedicine, 2010
Cutaneous tuberculosis, a rare form of extrapulmonary tuberculosis, has a wide variety of clinica... more Cutaneous tuberculosis, a rare form of extrapulmonary tuberculosis, has a wide variety of clinical presentations and continues to be one of the most important dermatological diseases in developing countries.The sites of predilection are neck, supraclavicular region, axilla, and groin. Single or multiple cutaneous and subcutaneous nodules first appear and breakdown later resulting in undermined ulcers with a purulent discharge, sinuses, and disfiguring scars. We report a multifocal case of scrofuloderma in a 47-year-old immunocompetent man treated successfully with four antituberculotic drugs, albeit lately due to the loss of awareness to the disease.
Annals of medical research, 1996
Annals of medical research, 1995
Annals of medical research, 1994
Annals of medical research, 1994