My Trà - Academia.edu (original) (raw)

Papers by My Trà

Tạp chí Y tế Công cộng, Dec 30, 2022

Background: Mental health is an important component of a person's state of health. According ... more Background: Mental health is an important component of a person's state of health. According to World Health Organization (WHO), there can be no health without mental health. Timely detection and care of mental health disorders are essential, contributing to health protection and improvement during the adolescent period and adulthood. Objectives: To describe the situation of mental health problems and identify some related factors in secondary school students in Hue city. Subjects and methods: A cross-sectional descriptive study was conducted with 500 secondary school students in Hue city from October 2021 to June 2022. The data was collected by face-to-face interviews using a pre-designed questionnaire that included social-demographic information, family and school problems, and the SDQ-25 scale which assesses adolescents' mental health status. Multivariate logistic regression analysis was used to identify factors associated with mental health. Results: Our research showed that 18.2% (95% CI: 15.1 - 21.8) students had abnormal mental health score; 27.4% (95% CI: 23.2 - 31.4) had borderline mental health score. The emotional problems had the highest rate (20.6%). Conduct problems, peer problem and hyperactivity/inattention accounted for 15.6%, 15.0% and 13.4% among the study subjects. 8.6% had prosocial problems. Some mental health-related factors were parents' marital status, frequency of physical activity, bedtime at the evening, family problems, school problems, and personal desires (p < 0.05). Conclusion: The percentage of students having mental health problems was high. It is necessary for family and school to encourage the participation in appropriate physical activities and change the habit of going to bed late to contribute to improving students' mental health status.

Tạp chí Y Dược học, Apr 1, 2023

Tóm tắt Đặt vấn đề: Theo hệ thống phân loại sinh dược học (Biopharmaceutical classification syste... more Tóm tắt Đặt vấn đề: Theo hệ thống phân loại sinh dược học (Biopharmaceutical classification system, BCS), ibuprofen thuộc nhóm II (tan kém, thấm tốt), nên sinh khả dụng không cao. Hiện nay, hệ tự vi nhũ hóa (SMEDDS) là một hệ mang thuốc giúp ổn định dược chất, tăng tính tan và thấm cho các chất kém tan, kém thấm, dễ bị thủy phân. Do đó, nghiên cứu này nhằm xây dựng công thức bào chế hệ tự vi nhũ hóa chứa ibuprofen dùng đường uống và đánh giá chất lượng hệ tự vi nhũ hóa chứa ibuprofen bào chế. Đối tượng và phương pháp nghiên cứu: Nghiên cứu sử dụng ibuprofen (Trung Quốc), các chất dầu (như acid oleic, Peceol,…), các chất diện hoạt (như Acrysol EL-135, Acrysol K-140,…), các chất đồng diện hoạt (như propylen glycol, Lauroglycol 90). Nghiên cứu đã tiến hành khảo sát, lựa chọn loại và các tỉ lệ tá dược, đánh giá các chỉ tiêu về hình thức, khả năng nhũ hóa, kích thước giọt, phân bố kích thước, định lượng. Kết quả: Hệ tự vi nhũ hóa chứa ibuprofen gồm các thành phần như ibuprofen 8,7%, Capryol 8,7%, Acrysol EL-135 66,08%, propylen glycol 16,52% với kích thước giọt 16,33 ± 0,124 nm, PDI 0,185 ± 0,003, có khả năng nhũ hóa nhanh tạo vi nhũ tương trong suốt trong vòng 30 giây khi khuấy trộn nhẹ nhàng với nước (tỉ lệ thể tích là 1:500, tt/tt). Kết luận: Đề tài đã bào chế thành công hệ tự vi nhũ hóa chứa ibuprofen hứa hẹn cho việc phát triển dạng bào chế dùng cho đường uống. Từ khóa: Ibuprofen, hệ tự vi nhũ hóa, SMEDDS.

Communications in Physics, Feb 9, 2023

We report a simple design of a water-based broadband metamaterial absorber in the terahertz regio... more We report a simple design of a water-based broadband metamaterial absorber in the terahertz region. The absorption performance of the designed absorber is simulated using numerical method. Due to the large frequency dispersive permittivity and high relative dielectric loss of water, the bandwidth of the proposed absorber can extend. The proposed structure achieves the absorption response over 0.9 in the broadband frequency range from 0.6 THz to 10 THz under normal incidence. Moreover, the absorbance maintains above 0.8 for a wide incident angle up to 60˚for transverse electronic (TE) mode and above 0.9 for a wide incident angle up to 70˚for transverse magnetic (TM) mode in the entire operating frequency range. Therefore, the designed absorber is a potential candidate for broadband THz applications.

Journal of Medicine and Pharmacy

Background: Adolescents who live in incomplete families may be vulnerable to various psychologica... more Background: Adolescents who live in incomplete families may be vulnerable to various psychological effects, ranging from mild to complex. This study aims to examine the need for psychological counseling among high school students whose parents are separated/divorced, and to identify factors associated with this need. Methods: A cross-sectional descriptive study was conducted on 309 high school students with separated/separated/divorced parents in Hue City. Results: The percentage of high school students with separated/divorced parents who need psychological counseling accounted for 40.5%. The need for psychological consultation about life skills and future orientation accounted for 54.4%, appearance and physicality accounted for 37.9%, family relationships accounted for 33.0% and problems with reproductive health and heterosexual friendship accounted for 31.4%. Factors related to the need for psychological counseling include the time of parents’ divorce, close friendship relationshi...

Journal of Medicine and Pharmacy

Background: Skin cancer is one of the most common cancers. Identifying some epidemiological and c... more Background: Skin cancer is one of the most common cancers. Identifying some epidemiological and clinical features of patients with skin cancer helps to suspect and diagnose early. Materials and methods: 44 skin cancer patients visiting and treating at Hue Central Hospital and Hue University of Medicine and Pharmacy Hospital from May 2020 to April 2021. Results: Most of the patients were over 60 years old (68.2%), the mean age was 66.3 ± 15.7 years old; Men and women were equal; Percentages with frequent exposure to sunlight, chemicals, and artificial light were respectively 54.6%, 45.5% and 43.2%; Precancerous lesions were accounted for 43.2%; The rates of basal cell carcinoma and squamous cell carcinoma were equal (43.2%), melanoma was lower (13.6%); Ulcers and bleeding were the most common lesions (accounting for 68.2% and 63.6%); The most common location was head - face - neck (54.5%); unique lesion was almost (88.6%); 54.6% of lesions were over 20mm in size; 31.8% having periphe...

Journal of Medicine and Pharmacy

Introduction: Glaucoma is the second leading cause of blindness. 90% of patients do not know they... more Introduction: Glaucoma is the second leading cause of blindness. 90% of patients do not know they have glaucoma in developing countries. One barrier preventing patients from accessing medical services for glaucoma is the limited knowledge, attitude, and practice about this disease. This requires further studies on knowledge, attitude, and practice about glaucoma, which serve as a basis solutions to improve service access. Objectives: 1) To describe the knowledge, attitude, the practice of glaucoma in persons over 40 years old in Hue city. 2) To find out some factors related to the knowledge, attitude, practice about glaucoma Methods: A descriptive cross-sectional method was conducted on 2.025 people over 40 years old in 27 wards of Hue city. Results: Good knowledge is accounted for 2.5%, positive attitude is accounted for 3.7%, a good practice is accounted for 2.5%. There was an association with statistical significance (p<0.05) between glaucoma practice and the following factors...

Journal of Medicine and Pharmacy

Introduction: Glaucoma is the leading cause of irreversible blindness and the second leading caus... more Introduction: Glaucoma is the leading cause of irreversible blindness and the second leading cause of blindness in general. Early detection and timely treatment help reduce the progression of the disease, indirectly limit the economic burden and ensure the quality of life for patients. Currently, access to glaucoma prevention medical services is difficult in developing countries due to limited access to eye care facilities. Objective: To assess the effectiveness of interventions to increase the access to glaucoma services of people over 40 years old in Hue city. Methods: Applied the study design for community intervention with the comparison between intervened and control groups. Results: Our intervention approach included 3 groups of activities: active communication to change behaviors, medical staff training to improve knowledge and practice, treatment and management for glaucoma patients, suspected glaucoma cases or those at risk factors for glaucoma. Results showed that, in the ...

Journal of Medicine and Pharmacy

Introduction: Glaucoma is a common eye disease that is quite dangerous to public health as one of... more Introduction: Glaucoma is a common eye disease that is quite dangerous to public health as one of the major causes of permanent blindness. Although glaucoma can be prevented, most glaucoma patients are underdiagnosed. It’s require a screening system to help patients detect glaucoma and treat it promptly. Objective: 1) To describe the glaucoma situation of person over 40 years old in Hue city. 2) To find out some factors related to glaucoma at study sites. Methods: A desciptive cross-sectional method was conducted with 2025 people over 40 years old in 27 wards of Hue city. Results: The percentage of glaucoma is 4.7%, with closed glaucoma accounting for 55.2%, with 9.1% of people suspected of glaucoma. The percentage of glaucoma patients suffering from blindness was 21.7%. There was an association between glaucoma and age, gender, hypertension, diabetes, cardiovascular disease, family history of glaucoma, previous history of ocular surgery. Conclusions: The percentage of glaucoma is 4...

Journal of Medicine and Pharmacy, 2020

Background: Cutaneous wart is a common disease caused by the infection of Human Papillomavirus, t... more Background: Cutaneous wart is a common disease caused by the infection of Human Papillomavirus, this disease has diverse clinical characteristics and many different treatments. We conducted this study to evaluate the clinical features and the efficacy electrosurgery treatment. Methods: A total 75 patients was diagnosed with cutaneous wart and treated by electrosurgery method at Dermatology Clinic of Hue University of Medicine and Pharmacy Hospital. Results: The age has a wide distribution. The female/male ratio was nearly egal. Most patients had a single lesion. Plantar wart was predominate with 63.3%. After the procedure, 90.8% of patients had mild and moderate pain. The rate of post-operative bleeding was high 85.3%. In the first week, the dried wound was 64.2%. The average healing time was about 4 weeks. The infection rate was 11%. Conclusion: The most common clinical form was plantar wart; electrosurgery had many advantages but some disadvantages in wound healing related to heat...

Journal of Medicine and Pharmacy, 2021

Pediatric dermatoses are common presentations in dermatology clinics. The pattern of pediatric de... more Pediatric dermatoses are common presentations in dermatology clinics. The pattern of pediatric dermatoses depends on ecological characteristics, sanitary conditions, social practices and genetics. The Dermatology Clinic, Hue University of Medicine and Pharmacy Hospital receives a lot of pediatric patients every day. Therefore, we conducted this research with the aim of contributing to a general overview of pediatric dermatology of children visiting this clinic. Materials and methods: A retrospective study was performed of patients under 16 years old, at the Dermatology Clinic from January 1, 2019 to December 30, 2019. Results: There were 1184 visits of children under 16, accounting for 16.8% of general visits. The proportion of male and female was nearly equal and the most common age group was 1-6 (49.7%). June, July, October and November were the months with the highest number of pediatric patients. The three most common skin diseases were dermatitis (35.3%), fungal infections (11....

Journal of Medicine and Pharmacy, 2021

Aims: Evaluating the effectiveness of Azithromycin combined with Adapalene in treating moderate a... more Aims: Evaluating the effectiveness of Azithromycin combined with Adapalene in treating moderate and severe Acne Vulgaris. Methodology: 38 patients diagnosed moderate and severe Acne vulgaris at Dermatology clinic, Hue University of Medicine and Pharmacy Hospital from May 2017 to March 2018, were examined and treated for 3 times at 4 weeks’ interval. Results: After 8 weeks of treatment, comedones, inflamed lesions and total lesions decreased in 56.8%, 79.7% and 65.6%, respectively. Lesions decreased statistical significantly (p < 0.0001). Qualitative evaluation showed 89.6% good and average results and over 90% patients satisfied with treatment. 4 in 38 patients have some kinds of side effects such as abdominal pain, nausea, vomit and diarrhea. Conclusions: Azithromycin combines with Adapalene showed good results in treating moderate and severe Acne Vulgaris.

Methods in Molecular Biology, 2021

The fast-moving CRISPR technology has allowed plant scientists to manipulate plant genomes in a t... more The fast-moving CRISPR technology has allowed plant scientists to manipulate plant genomes in a targeted manner. So far, most of the applications were focused on gene knocking out by creating indels. However, more precise genome editing tools are demanded to assist the introduction of functional single nucleotide polymorphisms (SNPs) in breeding programs. The CRISPR base editing tools were developed to meet this need. In this chapter, we present a cytidine deaminase base editing method for editing the point mutations that control the grain size and seed coat color in rice.

Journal of Medicine and Pharmacy, 2020

Objectives: To validate the Vietnamese version of the Premenstrual Syndrome Screening Tool (PSST)... more Objectives: To validate the Vietnamese version of the Premenstrual Syndrome Screening Tool (PSST). Materials and method: This was a cross-sectional study including 303 female-students in Hue University of Medicine and Pharmacy, who were between 18 and 45 years of age were approached to participate in this study. The PSST was translated from English to Vietnamese and conversely by obstetrician-gynecologist and psychiatrist independently. This initial version was piloted first in 20 women who were interviewed individually to make sure that participants and interviewers understood the items and the PSST has cultural adaptation before starting the interviews and collecting data. The participants were monitored premenstrual symptoms over at least two consecutive menstrual cycles by the Daily Record of Severity of Problems (DRSP), based on The Diagnostic and Statistical Manual of Mental Disorders Fifth Edition (DSM-5) criteria by American Psychiatric Association. Results: The prevalence o...

Background: Bacterial skin infections are common due to the bacteral invasion into the skin and c... more Background: Bacterial skin infections are common due to the bacteral invasion into the skin and cause a variety of clinical manifestation. In order to assess the characteristics of this group, we conducted this study to evaluate the clinical and main subclinical features. Methods: A total of 95 patients were diagnosed with bacterial skin infections at Dermatology Clinic of Hue University of Medicine and Pharmacy Hospital from June 2015 to May 2016, of which 34 patients had some tests and 19 patients had samples for culture. Results: The age group of 16 - 30 years old was the most popular: 50.5%; High rate of patients came for consultation in winter (49.5%), most patients had no fever. For functional symptoms, pain accounted for the highest proportion: 71.6%. The most common skin lesion was nodule: 38.8%, the lower extremities were the most common position: 38.9%. Furuncle had the highest incidence: 45.3%. For main laboratory tests, most patients had a normal number of leucocyte: 71....

We present a case study on the development of a formally verified PHP web social network applicat... more We present a case study on the development of a formally verified PHP web social network application. With the expansion of social media and our presence in the cyber world, the privacy and security of our content online have become a great concern. Our goal was to investigate whether we could formally verify privacy policies of a social network using the Event-B method. We chose to build a formally verified social network application for the following reasons: formally verifying the model with privacy policies shows consistency between the visibility of the user's content and the privacy setting of that content, and the privacy policies are readily formalized. The project involved building an Event-B model for the application in the Rodin environment, verifying that the user's data is visible to the correct set of people in the network using Rodin's automated theorem provers, and translating the model from Event-B to PHP code using the EventB2SQL tool. We also extended the EventB2SQL tool to generate the user interface components, reducing the amount of code that needed to be completed by hand. The end product of this project is an application that resembles a real-world social network. By developing a formally verified software system, we confirmed Event-B's ability to build models in the area of social network privacy policies.

Background A new species of the genus Pselaphodes Westwood, P. fansipanensis Bekchiev & Yin sp. n... more Background A new species of the genus Pselaphodes Westwood, P. fansipanensis Bekchiev & Yin sp. n., is described from northern Vietnam. The unique modification of the antennomeres 9-10 of the male readily separates the new species from all known congeners.

EcoHealth, Jan 24, 2015

The effect of newly emerging or re-emerging infectious diseases of zoonotic origin in human popul... more The effect of newly emerging or re-emerging infectious diseases of zoonotic origin in human populations can be potentially catastrophic, and large-scale investigations of such diseases are highly challenging. The monitoring of emergence events is subject to ascertainment bias, whether at the level of species discovery, emerging disease events, or disease outbreaks in human populations. Disease surveillance is generally performed post hoc, driven by a response to recent events and by the availability of detection and identification technologies. Additionally, the inventory of pathogens that exist in mammalian and other reservoirs is incomplete, and identifying those with the potential to cause disease in humans is rarely possible in advance. A major step in understanding the burden and diversity of zoonotic infections, the local behavioral and demographic risks of infection, and the risk of emergence of these pathogens in human populations is to establish surveillance networks in pop...

Tạp chí Y tế Công cộng, Dec 30, 2022

Background: Mental health is an important component of a person's state of health. According ... more Background: Mental health is an important component of a person's state of health. According to World Health Organization (WHO), there can be no health without mental health. Timely detection and care of mental health disorders are essential, contributing to health protection and improvement during the adolescent period and adulthood. Objectives: To describe the situation of mental health problems and identify some related factors in secondary school students in Hue city. Subjects and methods: A cross-sectional descriptive study was conducted with 500 secondary school students in Hue city from October 2021 to June 2022. The data was collected by face-to-face interviews using a pre-designed questionnaire that included social-demographic information, family and school problems, and the SDQ-25 scale which assesses adolescents' mental health status. Multivariate logistic regression analysis was used to identify factors associated with mental health. Results: Our research showed that 18.2% (95% CI: 15.1 - 21.8) students had abnormal mental health score; 27.4% (95% CI: 23.2 - 31.4) had borderline mental health score. The emotional problems had the highest rate (20.6%). Conduct problems, peer problem and hyperactivity/inattention accounted for 15.6%, 15.0% and 13.4% among the study subjects. 8.6% had prosocial problems. Some mental health-related factors were parents' marital status, frequency of physical activity, bedtime at the evening, family problems, school problems, and personal desires (p &lt; 0.05). Conclusion: The percentage of students having mental health problems was high. It is necessary for family and school to encourage the participation in appropriate physical activities and change the habit of going to bed late to contribute to improving students' mental health status.

Tạp chí Y Dược học, Apr 1, 2023

Tóm tắt Đặt vấn đề: Theo hệ thống phân loại sinh dược học (Biopharmaceutical classification syste... more Tóm tắt Đặt vấn đề: Theo hệ thống phân loại sinh dược học (Biopharmaceutical classification system, BCS), ibuprofen thuộc nhóm II (tan kém, thấm tốt), nên sinh khả dụng không cao. Hiện nay, hệ tự vi nhũ hóa (SMEDDS) là một hệ mang thuốc giúp ổn định dược chất, tăng tính tan và thấm cho các chất kém tan, kém thấm, dễ bị thủy phân. Do đó, nghiên cứu này nhằm xây dựng công thức bào chế hệ tự vi nhũ hóa chứa ibuprofen dùng đường uống và đánh giá chất lượng hệ tự vi nhũ hóa chứa ibuprofen bào chế. Đối tượng và phương pháp nghiên cứu: Nghiên cứu sử dụng ibuprofen (Trung Quốc), các chất dầu (như acid oleic, Peceol,…), các chất diện hoạt (như Acrysol EL-135, Acrysol K-140,…), các chất đồng diện hoạt (như propylen glycol, Lauroglycol 90). Nghiên cứu đã tiến hành khảo sát, lựa chọn loại và các tỉ lệ tá dược, đánh giá các chỉ tiêu về hình thức, khả năng nhũ hóa, kích thước giọt, phân bố kích thước, định lượng. Kết quả: Hệ tự vi nhũ hóa chứa ibuprofen gồm các thành phần như ibuprofen 8,7%, Capryol 8,7%, Acrysol EL-135 66,08%, propylen glycol 16,52% với kích thước giọt 16,33 ± 0,124 nm, PDI 0,185 ± 0,003, có khả năng nhũ hóa nhanh tạo vi nhũ tương trong suốt trong vòng 30 giây khi khuấy trộn nhẹ nhàng với nước (tỉ lệ thể tích là 1:500, tt/tt). Kết luận: Đề tài đã bào chế thành công hệ tự vi nhũ hóa chứa ibuprofen hứa hẹn cho việc phát triển dạng bào chế dùng cho đường uống. Từ khóa: Ibuprofen, hệ tự vi nhũ hóa, SMEDDS.

Communications in Physics, Feb 9, 2023

We report a simple design of a water-based broadband metamaterial absorber in the terahertz regio... more We report a simple design of a water-based broadband metamaterial absorber in the terahertz region. The absorption performance of the designed absorber is simulated using numerical method. Due to the large frequency dispersive permittivity and high relative dielectric loss of water, the bandwidth of the proposed absorber can extend. The proposed structure achieves the absorption response over 0.9 in the broadband frequency range from 0.6 THz to 10 THz under normal incidence. Moreover, the absorbance maintains above 0.8 for a wide incident angle up to 60˚for transverse electronic (TE) mode and above 0.9 for a wide incident angle up to 70˚for transverse magnetic (TM) mode in the entire operating frequency range. Therefore, the designed absorber is a potential candidate for broadband THz applications.

Journal of Medicine and Pharmacy

Background: Adolescents who live in incomplete families may be vulnerable to various psychologica... more Background: Adolescents who live in incomplete families may be vulnerable to various psychological effects, ranging from mild to complex. This study aims to examine the need for psychological counseling among high school students whose parents are separated/divorced, and to identify factors associated with this need. Methods: A cross-sectional descriptive study was conducted on 309 high school students with separated/separated/divorced parents in Hue City. Results: The percentage of high school students with separated/divorced parents who need psychological counseling accounted for 40.5%. The need for psychological consultation about life skills and future orientation accounted for 54.4%, appearance and physicality accounted for 37.9%, family relationships accounted for 33.0% and problems with reproductive health and heterosexual friendship accounted for 31.4%. Factors related to the need for psychological counseling include the time of parents’ divorce, close friendship relationshi...

Journal of Medicine and Pharmacy

Background: Skin cancer is one of the most common cancers. Identifying some epidemiological and c... more Background: Skin cancer is one of the most common cancers. Identifying some epidemiological and clinical features of patients with skin cancer helps to suspect and diagnose early. Materials and methods: 44 skin cancer patients visiting and treating at Hue Central Hospital and Hue University of Medicine and Pharmacy Hospital from May 2020 to April 2021. Results: Most of the patients were over 60 years old (68.2%), the mean age was 66.3 ± 15.7 years old; Men and women were equal; Percentages with frequent exposure to sunlight, chemicals, and artificial light were respectively 54.6%, 45.5% and 43.2%; Precancerous lesions were accounted for 43.2%; The rates of basal cell carcinoma and squamous cell carcinoma were equal (43.2%), melanoma was lower (13.6%); Ulcers and bleeding were the most common lesions (accounting for 68.2% and 63.6%); The most common location was head - face - neck (54.5%); unique lesion was almost (88.6%); 54.6% of lesions were over 20mm in size; 31.8% having periphe...

Journal of Medicine and Pharmacy

Introduction: Glaucoma is the second leading cause of blindness. 90% of patients do not know they... more Introduction: Glaucoma is the second leading cause of blindness. 90% of patients do not know they have glaucoma in developing countries. One barrier preventing patients from accessing medical services for glaucoma is the limited knowledge, attitude, and practice about this disease. This requires further studies on knowledge, attitude, and practice about glaucoma, which serve as a basis solutions to improve service access. Objectives: 1) To describe the knowledge, attitude, the practice of glaucoma in persons over 40 years old in Hue city. 2) To find out some factors related to the knowledge, attitude, practice about glaucoma Methods: A descriptive cross-sectional method was conducted on 2.025 people over 40 years old in 27 wards of Hue city. Results: Good knowledge is accounted for 2.5%, positive attitude is accounted for 3.7%, a good practice is accounted for 2.5%. There was an association with statistical significance (p<0.05) between glaucoma practice and the following factors...

Journal of Medicine and Pharmacy

Introduction: Glaucoma is the leading cause of irreversible blindness and the second leading caus... more Introduction: Glaucoma is the leading cause of irreversible blindness and the second leading cause of blindness in general. Early detection and timely treatment help reduce the progression of the disease, indirectly limit the economic burden and ensure the quality of life for patients. Currently, access to glaucoma prevention medical services is difficult in developing countries due to limited access to eye care facilities. Objective: To assess the effectiveness of interventions to increase the access to glaucoma services of people over 40 years old in Hue city. Methods: Applied the study design for community intervention with the comparison between intervened and control groups. Results: Our intervention approach included 3 groups of activities: active communication to change behaviors, medical staff training to improve knowledge and practice, treatment and management for glaucoma patients, suspected glaucoma cases or those at risk factors for glaucoma. Results showed that, in the ...

Journal of Medicine and Pharmacy

Introduction: Glaucoma is a common eye disease that is quite dangerous to public health as one of... more Introduction: Glaucoma is a common eye disease that is quite dangerous to public health as one of the major causes of permanent blindness. Although glaucoma can be prevented, most glaucoma patients are underdiagnosed. It’s require a screening system to help patients detect glaucoma and treat it promptly. Objective: 1) To describe the glaucoma situation of person over 40 years old in Hue city. 2) To find out some factors related to glaucoma at study sites. Methods: A desciptive cross-sectional method was conducted with 2025 people over 40 years old in 27 wards of Hue city. Results: The percentage of glaucoma is 4.7%, with closed glaucoma accounting for 55.2%, with 9.1% of people suspected of glaucoma. The percentage of glaucoma patients suffering from blindness was 21.7%. There was an association between glaucoma and age, gender, hypertension, diabetes, cardiovascular disease, family history of glaucoma, previous history of ocular surgery. Conclusions: The percentage of glaucoma is 4...

Journal of Medicine and Pharmacy, 2020

Background: Cutaneous wart is a common disease caused by the infection of Human Papillomavirus, t... more Background: Cutaneous wart is a common disease caused by the infection of Human Papillomavirus, this disease has diverse clinical characteristics and many different treatments. We conducted this study to evaluate the clinical features and the efficacy electrosurgery treatment. Methods: A total 75 patients was diagnosed with cutaneous wart and treated by electrosurgery method at Dermatology Clinic of Hue University of Medicine and Pharmacy Hospital. Results: The age has a wide distribution. The female/male ratio was nearly egal. Most patients had a single lesion. Plantar wart was predominate with 63.3%. After the procedure, 90.8% of patients had mild and moderate pain. The rate of post-operative bleeding was high 85.3%. In the first week, the dried wound was 64.2%. The average healing time was about 4 weeks. The infection rate was 11%. Conclusion: The most common clinical form was plantar wart; electrosurgery had many advantages but some disadvantages in wound healing related to heat...

Journal of Medicine and Pharmacy, 2021

Pediatric dermatoses are common presentations in dermatology clinics. The pattern of pediatric de... more Pediatric dermatoses are common presentations in dermatology clinics. The pattern of pediatric dermatoses depends on ecological characteristics, sanitary conditions, social practices and genetics. The Dermatology Clinic, Hue University of Medicine and Pharmacy Hospital receives a lot of pediatric patients every day. Therefore, we conducted this research with the aim of contributing to a general overview of pediatric dermatology of children visiting this clinic. Materials and methods: A retrospective study was performed of patients under 16 years old, at the Dermatology Clinic from January 1, 2019 to December 30, 2019. Results: There were 1184 visits of children under 16, accounting for 16.8% of general visits. The proportion of male and female was nearly equal and the most common age group was 1-6 (49.7%). June, July, October and November were the months with the highest number of pediatric patients. The three most common skin diseases were dermatitis (35.3%), fungal infections (11....

Journal of Medicine and Pharmacy, 2021

Aims: Evaluating the effectiveness of Azithromycin combined with Adapalene in treating moderate a... more Aims: Evaluating the effectiveness of Azithromycin combined with Adapalene in treating moderate and severe Acne Vulgaris. Methodology: 38 patients diagnosed moderate and severe Acne vulgaris at Dermatology clinic, Hue University of Medicine and Pharmacy Hospital from May 2017 to March 2018, were examined and treated for 3 times at 4 weeks’ interval. Results: After 8 weeks of treatment, comedones, inflamed lesions and total lesions decreased in 56.8%, 79.7% and 65.6%, respectively. Lesions decreased statistical significantly (p < 0.0001). Qualitative evaluation showed 89.6% good and average results and over 90% patients satisfied with treatment. 4 in 38 patients have some kinds of side effects such as abdominal pain, nausea, vomit and diarrhea. Conclusions: Azithromycin combines with Adapalene showed good results in treating moderate and severe Acne Vulgaris.

Methods in Molecular Biology, 2021

The fast-moving CRISPR technology has allowed plant scientists to manipulate plant genomes in a t... more The fast-moving CRISPR technology has allowed plant scientists to manipulate plant genomes in a targeted manner. So far, most of the applications were focused on gene knocking out by creating indels. However, more precise genome editing tools are demanded to assist the introduction of functional single nucleotide polymorphisms (SNPs) in breeding programs. The CRISPR base editing tools were developed to meet this need. In this chapter, we present a cytidine deaminase base editing method for editing the point mutations that control the grain size and seed coat color in rice.

Journal of Medicine and Pharmacy, 2020

Objectives: To validate the Vietnamese version of the Premenstrual Syndrome Screening Tool (PSST)... more Objectives: To validate the Vietnamese version of the Premenstrual Syndrome Screening Tool (PSST). Materials and method: This was a cross-sectional study including 303 female-students in Hue University of Medicine and Pharmacy, who were between 18 and 45 years of age were approached to participate in this study. The PSST was translated from English to Vietnamese and conversely by obstetrician-gynecologist and psychiatrist independently. This initial version was piloted first in 20 women who were interviewed individually to make sure that participants and interviewers understood the items and the PSST has cultural adaptation before starting the interviews and collecting data. The participants were monitored premenstrual symptoms over at least two consecutive menstrual cycles by the Daily Record of Severity of Problems (DRSP), based on The Diagnostic and Statistical Manual of Mental Disorders Fifth Edition (DSM-5) criteria by American Psychiatric Association. Results: The prevalence o...

Background: Bacterial skin infections are common due to the bacteral invasion into the skin and c... more Background: Bacterial skin infections are common due to the bacteral invasion into the skin and cause a variety of clinical manifestation. In order to assess the characteristics of this group, we conducted this study to evaluate the clinical and main subclinical features. Methods: A total of 95 patients were diagnosed with bacterial skin infections at Dermatology Clinic of Hue University of Medicine and Pharmacy Hospital from June 2015 to May 2016, of which 34 patients had some tests and 19 patients had samples for culture. Results: The age group of 16 - 30 years old was the most popular: 50.5%; High rate of patients came for consultation in winter (49.5%), most patients had no fever. For functional symptoms, pain accounted for the highest proportion: 71.6%. The most common skin lesion was nodule: 38.8%, the lower extremities were the most common position: 38.9%. Furuncle had the highest incidence: 45.3%. For main laboratory tests, most patients had a normal number of leucocyte: 71....

We present a case study on the development of a formally verified PHP web social network applicat... more We present a case study on the development of a formally verified PHP web social network application. With the expansion of social media and our presence in the cyber world, the privacy and security of our content online have become a great concern. Our goal was to investigate whether we could formally verify privacy policies of a social network using the Event-B method. We chose to build a formally verified social network application for the following reasons: formally verifying the model with privacy policies shows consistency between the visibility of the user's content and the privacy setting of that content, and the privacy policies are readily formalized. The project involved building an Event-B model for the application in the Rodin environment, verifying that the user's data is visible to the correct set of people in the network using Rodin's automated theorem provers, and translating the model from Event-B to PHP code using the EventB2SQL tool. We also extended the EventB2SQL tool to generate the user interface components, reducing the amount of code that needed to be completed by hand. The end product of this project is an application that resembles a real-world social network. By developing a formally verified software system, we confirmed Event-B's ability to build models in the area of social network privacy policies.

Background A new species of the genus Pselaphodes Westwood, P. fansipanensis Bekchiev & Yin sp. n... more Background A new species of the genus Pselaphodes Westwood, P. fansipanensis Bekchiev & Yin sp. n., is described from northern Vietnam. The unique modification of the antennomeres 9-10 of the male readily separates the new species from all known congeners.

EcoHealth, Jan 24, 2015

The effect of newly emerging or re-emerging infectious diseases of zoonotic origin in human popul... more The effect of newly emerging or re-emerging infectious diseases of zoonotic origin in human populations can be potentially catastrophic, and large-scale investigations of such diseases are highly challenging. The monitoring of emergence events is subject to ascertainment bias, whether at the level of species discovery, emerging disease events, or disease outbreaks in human populations. Disease surveillance is generally performed post hoc, driven by a response to recent events and by the availability of detection and identification technologies. Additionally, the inventory of pathogens that exist in mammalian and other reservoirs is incomplete, and identifying those with the potential to cause disease in humans is rarely possible in advance. A major step in understanding the burden and diversity of zoonotic infections, the local behavioral and demographic risks of infection, and the risk of emergence of these pathogens in human populations is to establish surveillance networks in pop...