Naeem Khan - Academia.edu (original) (raw)

Papers by Naeem Khan

In the present study we are reporting the antifungal and immunomodulatory activities of various f... more In the present study we are reporting the antifungal and immunomodulatory activities of various fractions of Nepeta suavis, such as, chloroform, hexane, butanol, ethyl acetate and aqueous. The chloroform and butanol fractions showed inhibitory action against Trichophyton longifusus, Aspergillus flavus, Candida albicans, Fusarium solani and Microsporumcanis. In case of immunomodulatory study, the chloroform fraction showed clear modulatory effect for oxidative burst of polymorphoneutrophils and ethylacetate for the whole blood, while the aqueous fraction showed moderate inhibition. Hence, both the chloroform and ethylacetate fractions of Nepeta suavis are recommended further for the identification and isolation of active compounds, responsible for the observed effects.

African Journal of Biotechnology, Aug 8, 2011

Heavy metals such as Cr, Fe, Zn, Mn, Ni, Pb, Cu and Cd, and inorganic ions like HCO3 -, CO 3 2-, ... more Heavy metals such as Cr, Fe, Zn, Mn, Ni, Pb, Cu and Cd, and inorganic ions like HCO3 -, CO 3 2-, Ca 2+ , Mg 2+ , Cl -, Na + , SO 4 2-, NO 3 -, Fe 2+ and F were investigated in medicinally important plants: Taraxacam officinale, Cichorium intybus and Figonia critica, applying atomic absorption spectrophotometer techniques. In the studied herbs, there were variable amounts of heavy metals and inorganic ions. The purpose of this study was to standardize heavy metals contamination in various indigenous medicinal plants and to create awareness among the public regarding its safe use at collection areas (containing high level of heavy metals) and their adverse health effects.

African Journal of Biotechnology, Mar 25, 2011

... ISSN 1684-5315 © 2011 Academic Journals. Full Length Research. Biotransformation of ß-estradi... more ... ISSN 1684-5315 © 2011 Academic Journals. Full Length Research. Biotransformation of ß-estradiol isolated from Sonchus eruca. Javid Hussain 1,5* , Zia Muhammad 1 , Riaz Ullah 1,4 , Nargis Jamila 3 , Shabir Ahmad 1 , Naeem Khan 1 , Sultan Ayaz 2 and Sajjad Haider 4. ...

Asian Journal of Plant Sciences, 2003

International Journal of Innovation and Applied Studies, Feb 2, 2014

This paper is focused on modeling and introducing a new control strategy for a condensate water s... more This paper is focused on modeling and introducing a new control strategy for a condensate water system. Current control strategy of the system is simple feedback control system with one PID controller. Results of current control strategy were taken into account for improvements in terms of system stability, valve movements and unwanted transients. Problems found in condensate system were; large variations in process variable, extra movement in valve positions and inefficient opening of valves. Simulation model with current control strategy and results as of real power plant was created and validated, as new control strategy can be applied and results can be compared. The main recommendation to improve the control system performance was found through PID cascade control strategy that could assist the current controller. The recommendation was evaluated by designing and implementing the cascade control strategy on the Dymola simulation model. Simulation results pointed out considerable increase in system performance according to the requirements of Ringhals (Vattenfall) AB Sweden.

This study aimed to compare volatile compounds among fresh and semi-fermented leave of Zukro tea.... more This study aimed to compare volatile compounds among fresh and semi-fermented leave of Zukro tea. Volatile compounds were extracted the using SDE method and analyzed by GC/MS. A total of 93 and 76 compounds were identified in fresh and semi-fermented leave, respectively. Alcohols were the predominant chemical group, with a proportion of 76.96% and 56.85% in fresh and semi-fermented leaves. The major alcohol compound in both samples was phytol, which had a higher aroma threshold and resulted from hydrolysis of chlorophyll. Terpenoid compounds were present at 29.1 and 24.9 mg/kg, in fresh and semi-fermented leaves, respectively. Terpene alcohols such as linalool and geraniol were present as major volatile compounds at concentrations of 7.8 and 14.4 mg/kg in fresh leaves of Zukro tea, respectively. The contents of these two terpene alcohols were 4.4 and 3.1 mg/kg in semi-fermented leaves. C6 compounds were present at 7.8 mg/kg in fresh leaves but decreased to 1.0 mg/kg in semi-fermented leave. The contents of esters, ketones, hydrocarbons, and N-containing compounds all increased after semi-fermentation.

Heavy metals such as Cr, Fe, Zn, Mn, Ni, Pb, Cu and Cd, and inorganic ions like HCO3 -, CO 3 2-, ... more Heavy metals such as Cr, Fe, Zn, Mn, Ni, Pb, Cu and Cd, and inorganic ions like HCO3 -, CO 3 2-, Ca 2+ , Mg 2+ , Cl -, Na + , SO 4 2-, NO 3 -, Fe 2+ and F were investigated in medicinally important plants: Taraxacam officinale, Cichorium intybus and Figonia critica, applying atomic absorption spectrophotometer techniques. In the studied herbs, there were variable amounts of heavy metals and inorganic ions. The purpose of this study was to standardize heavy metals contamination in various indigenous medicinal plants and to create awareness among the public regarding its safe use at collection areas (containing high level of heavy metals) and their adverse health effects.

African Journal of Biotechnology, 2012

Microbial contamination of ground water sources is a common problem in all the big cities, which ... more Microbial contamination of ground water sources is a common problem in all the big cities, which endangers health and impairs quality of living . To assess this, 39 water samples were collected from highly populated 13 union councils from the urban area of district Mardan. Faecal coliform and Escherichia coli were investigated both qualitatively and quantitatively. Qualitative study showed that faecal coliform was found in 90% samples and E. coli in 56% samples. Quantitatively, faecal coliform most probable number (MPN) was ranging from 1601 to 2400 for about 28% samples, followed by 551 to 1600 and 201 to 550 for 20% samples each, 40 to 200 for 18% samples and less than 40 for about 13% samples. The major cause of the bacteriological contamination was found to be the extent of susceptibility of the water sources to intrusions from the nearest contamination source.

International Journal of Physical Sciences, 2012

Safe drinking water is one of the basic human rights and essential need for healthy life. In Paki... more Safe drinking water is one of the basic human rights and essential need for healthy life. In Pakistan, the quality of drinking water is not being managed properly and various studies provide evidence that most of the drinking-water supplies are contaminated. In this study, 60 drinking water samples from both urban and rural areas of district Kohat were analyzed chemically and microbiologically, to find out their suitability for drinking purposes. Fifty-four samples were collected from hand pumps, streams, tanks, wells and tube wells, at 15 main population zones selected. Six bottled water samples were also taken from the open market for analysis. These were investigated for various chemical parameters including sodium (Na + ), potassium (K + ), sulfate (SO 4 2-), phosphate (PO 4 -3

In this paper an optimal Kalman filter estimator is designed for the plants subject to loss of da... more In this paper an optimal Kalman filter estimator is designed for the plants subject to loss of data or insufficient observation. The methodology utilized is based on the closed-loop compensation algorithm which is computed through the so-called Modified Linear Prediction Coefficient (MLPC) observation scheme. The proposed approach is aimed at the artificial observation vector which in fact corrects the prediction cycle when loss of data occurs. We present a non-trivial mass-spring-dashpot case study selected to demonstrate some of the key issues that arise when using the proposed optimal filtering algorithm under missing data.

Natural Product Research, 2015

The dichloromethane bark extract of Garcinia hombroniana yielded one new cycloartane triterpene; ... more The dichloromethane bark extract of Garcinia hombroniana yielded one new cycloartane triterpene; (22Z,24E)-3β-hydroxycycloart-14,22,24-trien-26-oic acid (1) together with five known compounds: garcihombronane G (2), garcihombronane J (3), 3β acetoxy-9α-hydroxy-17,14-friedolanostan-14,24-dien-26-oic acid (4), (22Z, 24E)-3β, 9α-dihydroxy-17,14-friedolanostan-14,22,24-trien-26-oic acid (5) and 3β, 23α-dihydroxy-17,14-friedolanostan-8,14,24-trien-26-oic acid (6). Their structures were established by the spectral techniques of NMR and ESI-MS. These compounds together with some previously isolated compounds; garcihombronane B (7), garcihombronane D (8) 2,3',4,5'-tetrahydroxy-6-methoxybenzophenone (9), volkensiflavone (10), 4''-O-methyll-volkensiflavone (11), volkensiflavone-7-O-glucopyranoside (12), volkensiflavone-7-O-rhamnopyranoside (13), Morelloflavone (14),…

International journal of physical sciences

A total of 39 drinking water sources were analyzed for important physicochemical parameters to ev... more A total of 39 drinking water sources were analyzed for important physicochemical parameters to evaluate their suitability for human consumption. Samples were collected from the ground water supplies (tube wells, open wells and hand pumps) of highly populated 13 union councils from the urban area of district Mardan. Physical parameters studied include temperature, color, taste, odor, total dissolved solids (TDS), pH, electrical conductivity (EC), and turbidity. The chemical parameters analyzed were, total hardness, calcium (Ca), magnesium (Mg), bicarbonate (HCO3) and alkalinity. Results showed that EC of 38%, taste of 23%, hardness of 20% and TDS of 15% samples were not in the permissible ranges specified by the World Health Organization (WHO) and Pakistan recommended standards for drinking water. The deterioration of various drinking water sources were found to be dependent upon the geological strata of the area, waste sources and damaged outlived distribution system passing through...

World Applied Sciences Journal

In Pakistan, the quality of drinking water is not properly managed and various studies provide ev... more In Pakistan, the quality of drinking water is not properly managed and various studies provide evidence that most of the drinking-water sources are contaminated. In this study, 39 water samples were collected from open wells, hand pumps and public water supply schemes of the highly populated 13 union councils from the urban area of district Mardan, to find out their suitability for drinking purposes. These were investigated for various chemical parameters including sulfate (SO ), fluoride (F), chloride (Cl), ), nitrate (NO ), 4 3 sodium (Na), potassium (K), iron (Fe) and arsenic (As), using standard methods of analysis recommended by American Public Health Association (APHA). The results of various parameters showed variations from the WHO and Pakistan recommended standard values for drinking water. The Na of 15%, SO of 13% and Cl of 4 2- - 2% samples were found high than the WHO/Pakistan recommended values for drinking water. Geological strata of the area, surrounding pollution sou...

Food irradiation has recently become one of the most successful techniques to preserve food with ... more Food irradiation has recently become one of the most successful techniques to preserve food with increased shelf life. This study aims to analyze hydrocarbons in almonds (Prunus amygosalus L.) and peanuts (Arachis hypogaea) induced by electron beam irradiation. The samples were irradiated at 0, 1, 3, 5 and 10 kGy by e-beam and using florisil column chromatography fat, and content was extracted. The induced hydrocarbons were identified using gas chromatography-mass spectrometry (GC/MS). The major hydrocarbons in both irradiated samples were 1,7-hexadecadiene () and 8-heptadecene () from oleic acid, 1,7,10-hexadecatriene () and 6,9-heptadecadiene () from linoleic acid and 1-tetradecene () and pentadecane () from palmitic acid. Concentrations of the hydrocarbons produced by e-beam were found to be depended upon the composition of fatty acid in both almonds and peanuts. The compound was found to be higher than compound in oleic acid and palmitic acid, while in case of linoleic acid, com...

In the present study we are reporting the antifungal and immunomodulatory activities of various f... more In the present study we are reporting the antifungal and immunomodulatory activities of various fractions of Nepeta suavis, such as, chloroform, hexane, butanol, ethyl acetate and aqueous. The chloroform and butanol fractions showed inhibitory action against Trichophyton longifusus, Aspergillus flavus, Candida albicans, Fusarium solani and Microsporumcanis. In case of immunomodulatory study, the chloroform fraction showed clear modulatory effect for oxidative burst of polymorphoneutrophils and ethylacetate for the whole blood, while the aqueous fraction showed moderate inhibition. Hence, both the chloroform and ethylacetate fractions of Nepeta suavis are recommended further for the identification and isolation of active compounds, responsible for the observed effects.

African Journal of Biotechnology, Aug 8, 2011

Heavy metals such as Cr, Fe, Zn, Mn, Ni, Pb, Cu and Cd, and inorganic ions like HCO3 -, CO 3 2-, ... more Heavy metals such as Cr, Fe, Zn, Mn, Ni, Pb, Cu and Cd, and inorganic ions like HCO3 -, CO 3 2-, Ca 2+ , Mg 2+ , Cl -, Na + , SO 4 2-, NO 3 -, Fe 2+ and F were investigated in medicinally important plants: Taraxacam officinale, Cichorium intybus and Figonia critica, applying atomic absorption spectrophotometer techniques. In the studied herbs, there were variable amounts of heavy metals and inorganic ions. The purpose of this study was to standardize heavy metals contamination in various indigenous medicinal plants and to create awareness among the public regarding its safe use at collection areas (containing high level of heavy metals) and their adverse health effects.

African Journal of Biotechnology, Mar 25, 2011

... ISSN 1684-5315 © 2011 Academic Journals. Full Length Research. Biotransformation of ß-estradi... more ... ISSN 1684-5315 © 2011 Academic Journals. Full Length Research. Biotransformation of ß-estradiol isolated from Sonchus eruca. Javid Hussain 1,5* , Zia Muhammad 1 , Riaz Ullah 1,4 , Nargis Jamila 3 , Shabir Ahmad 1 , Naeem Khan 1 , Sultan Ayaz 2 and Sajjad Haider 4. ...

Asian Journal of Plant Sciences, 2003

International Journal of Innovation and Applied Studies, Feb 2, 2014

This paper is focused on modeling and introducing a new control strategy for a condensate water s... more This paper is focused on modeling and introducing a new control strategy for a condensate water system. Current control strategy of the system is simple feedback control system with one PID controller. Results of current control strategy were taken into account for improvements in terms of system stability, valve movements and unwanted transients. Problems found in condensate system were; large variations in process variable, extra movement in valve positions and inefficient opening of valves. Simulation model with current control strategy and results as of real power plant was created and validated, as new control strategy can be applied and results can be compared. The main recommendation to improve the control system performance was found through PID cascade control strategy that could assist the current controller. The recommendation was evaluated by designing and implementing the cascade control strategy on the Dymola simulation model. Simulation results pointed out considerable increase in system performance according to the requirements of Ringhals (Vattenfall) AB Sweden.

This study aimed to compare volatile compounds among fresh and semi-fermented leave of Zukro tea.... more This study aimed to compare volatile compounds among fresh and semi-fermented leave of Zukro tea. Volatile compounds were extracted the using SDE method and analyzed by GC/MS. A total of 93 and 76 compounds were identified in fresh and semi-fermented leave, respectively. Alcohols were the predominant chemical group, with a proportion of 76.96% and 56.85% in fresh and semi-fermented leaves. The major alcohol compound in both samples was phytol, which had a higher aroma threshold and resulted from hydrolysis of chlorophyll. Terpenoid compounds were present at 29.1 and 24.9 mg/kg, in fresh and semi-fermented leaves, respectively. Terpene alcohols such as linalool and geraniol were present as major volatile compounds at concentrations of 7.8 and 14.4 mg/kg in fresh leaves of Zukro tea, respectively. The contents of these two terpene alcohols were 4.4 and 3.1 mg/kg in semi-fermented leaves. C6 compounds were present at 7.8 mg/kg in fresh leaves but decreased to 1.0 mg/kg in semi-fermented leave. The contents of esters, ketones, hydrocarbons, and N-containing compounds all increased after semi-fermentation.

Heavy metals such as Cr, Fe, Zn, Mn, Ni, Pb, Cu and Cd, and inorganic ions like HCO3 -, CO 3 2-, ... more Heavy metals such as Cr, Fe, Zn, Mn, Ni, Pb, Cu and Cd, and inorganic ions like HCO3 -, CO 3 2-, Ca 2+ , Mg 2+ , Cl -, Na + , SO 4 2-, NO 3 -, Fe 2+ and F were investigated in medicinally important plants: Taraxacam officinale, Cichorium intybus and Figonia critica, applying atomic absorption spectrophotometer techniques. In the studied herbs, there were variable amounts of heavy metals and inorganic ions. The purpose of this study was to standardize heavy metals contamination in various indigenous medicinal plants and to create awareness among the public regarding its safe use at collection areas (containing high level of heavy metals) and their adverse health effects.

African Journal of Biotechnology, 2012

Microbial contamination of ground water sources is a common problem in all the big cities, which ... more Microbial contamination of ground water sources is a common problem in all the big cities, which endangers health and impairs quality of living . To assess this, 39 water samples were collected from highly populated 13 union councils from the urban area of district Mardan. Faecal coliform and Escherichia coli were investigated both qualitatively and quantitatively. Qualitative study showed that faecal coliform was found in 90% samples and E. coli in 56% samples. Quantitatively, faecal coliform most probable number (MPN) was ranging from 1601 to 2400 for about 28% samples, followed by 551 to 1600 and 201 to 550 for 20% samples each, 40 to 200 for 18% samples and less than 40 for about 13% samples. The major cause of the bacteriological contamination was found to be the extent of susceptibility of the water sources to intrusions from the nearest contamination source.

International Journal of Physical Sciences, 2012

Safe drinking water is one of the basic human rights and essential need for healthy life. In Paki... more Safe drinking water is one of the basic human rights and essential need for healthy life. In Pakistan, the quality of drinking water is not being managed properly and various studies provide evidence that most of the drinking-water supplies are contaminated. In this study, 60 drinking water samples from both urban and rural areas of district Kohat were analyzed chemically and microbiologically, to find out their suitability for drinking purposes. Fifty-four samples were collected from hand pumps, streams, tanks, wells and tube wells, at 15 main population zones selected. Six bottled water samples were also taken from the open market for analysis. These were investigated for various chemical parameters including sodium (Na + ), potassium (K + ), sulfate (SO 4 2-), phosphate (PO 4 -3

In this paper an optimal Kalman filter estimator is designed for the plants subject to loss of da... more In this paper an optimal Kalman filter estimator is designed for the plants subject to loss of data or insufficient observation. The methodology utilized is based on the closed-loop compensation algorithm which is computed through the so-called Modified Linear Prediction Coefficient (MLPC) observation scheme. The proposed approach is aimed at the artificial observation vector which in fact corrects the prediction cycle when loss of data occurs. We present a non-trivial mass-spring-dashpot case study selected to demonstrate some of the key issues that arise when using the proposed optimal filtering algorithm under missing data.

Natural Product Research, 2015

The dichloromethane bark extract of Garcinia hombroniana yielded one new cycloartane triterpene; ... more The dichloromethane bark extract of Garcinia hombroniana yielded one new cycloartane triterpene; (22Z,24E)-3β-hydroxycycloart-14,22,24-trien-26-oic acid (1) together with five known compounds: garcihombronane G (2), garcihombronane J (3), 3β acetoxy-9α-hydroxy-17,14-friedolanostan-14,24-dien-26-oic acid (4), (22Z, 24E)-3β, 9α-dihydroxy-17,14-friedolanostan-14,22,24-trien-26-oic acid (5) and 3β, 23α-dihydroxy-17,14-friedolanostan-8,14,24-trien-26-oic acid (6). Their structures were established by the spectral techniques of NMR and ESI-MS. These compounds together with some previously isolated compounds; garcihombronane B (7), garcihombronane D (8) 2,3',4,5'-tetrahydroxy-6-methoxybenzophenone (9), volkensiflavone (10), 4''-O-methyll-volkensiflavone (11), volkensiflavone-7-O-glucopyranoside (12), volkensiflavone-7-O-rhamnopyranoside (13), Morelloflavone (14),…

International journal of physical sciences

A total of 39 drinking water sources were analyzed for important physicochemical parameters to ev... more A total of 39 drinking water sources were analyzed for important physicochemical parameters to evaluate their suitability for human consumption. Samples were collected from the ground water supplies (tube wells, open wells and hand pumps) of highly populated 13 union councils from the urban area of district Mardan. Physical parameters studied include temperature, color, taste, odor, total dissolved solids (TDS), pH, electrical conductivity (EC), and turbidity. The chemical parameters analyzed were, total hardness, calcium (Ca), magnesium (Mg), bicarbonate (HCO3) and alkalinity. Results showed that EC of 38%, taste of 23%, hardness of 20% and TDS of 15% samples were not in the permissible ranges specified by the World Health Organization (WHO) and Pakistan recommended standards for drinking water. The deterioration of various drinking water sources were found to be dependent upon the geological strata of the area, waste sources and damaged outlived distribution system passing through...

World Applied Sciences Journal

In Pakistan, the quality of drinking water is not properly managed and various studies provide ev... more In Pakistan, the quality of drinking water is not properly managed and various studies provide evidence that most of the drinking-water sources are contaminated. In this study, 39 water samples were collected from open wells, hand pumps and public water supply schemes of the highly populated 13 union councils from the urban area of district Mardan, to find out their suitability for drinking purposes. These were investigated for various chemical parameters including sulfate (SO ), fluoride (F), chloride (Cl), ), nitrate (NO ), 4 3 sodium (Na), potassium (K), iron (Fe) and arsenic (As), using standard methods of analysis recommended by American Public Health Association (APHA). The results of various parameters showed variations from the WHO and Pakistan recommended standard values for drinking water. The Na of 15%, SO of 13% and Cl of 4 2- - 2% samples were found high than the WHO/Pakistan recommended values for drinking water. Geological strata of the area, surrounding pollution sou...

Food irradiation has recently become one of the most successful techniques to preserve food with ... more Food irradiation has recently become one of the most successful techniques to preserve food with increased shelf life. This study aims to analyze hydrocarbons in almonds (Prunus amygosalus L.) and peanuts (Arachis hypogaea) induced by electron beam irradiation. The samples were irradiated at 0, 1, 3, 5 and 10 kGy by e-beam and using florisil column chromatography fat, and content was extracted. The induced hydrocarbons were identified using gas chromatography-mass spectrometry (GC/MS). The major hydrocarbons in both irradiated samples were 1,7-hexadecadiene () and 8-heptadecene () from oleic acid, 1,7,10-hexadecatriene () and 6,9-heptadecadiene () from linoleic acid and 1-tetradecene () and pentadecane () from palmitic acid. Concentrations of the hydrocarbons produced by e-beam were found to be depended upon the composition of fatty acid in both almonds and peanuts. The compound was found to be higher than compound in oleic acid and palmitic acid, while in case of linoleic acid, com...