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Papers by Naiara Rodriguez-Florez

Aging and skeletal diseases lead to an increase in bone fracture risk. In particular, micro-poros... more Aging and skeletal diseases lead to an increase in bone fracture risk. In particular, micro-porosity might have a profound influence on crack propagation. In osteogenesis imperfecta murine (oim) bones, which represent the moderate to severe condition of osteogenesis imperfecta in humans, a genetic mutation results in high bone fragility. Oim bones have more numerous and branched vascular canals compared to their wild type (WT) controls [1]. The objective of this study is to use the Extended Element Method (XFEM) tools provided by Abaqus (v 6.12) to characterize the role of vascular canals in mouse cortical bone during crack propagation. The topology of transverse cross sections of oim and WT tibial mid-diaphysis were captured with synchrotron radiation-based computed tomography and used to create two-dimensional models. Although XFEM allows modelling crack propagation along an arbitrary, solution-dependent path, there are some limitations when using this technique to model bone at t...

Journal of Bone and Mineral Research, 2014

Journal of the Mechanical Behavior of Biomedical Materials, 2013

Journal of Biomechanics, 2014

Aging and skeletal diseases lead to an increase in bone fracture risk. In particular, micro-poros... more Aging and skeletal diseases lead to an increase in bone fracture risk. In particular, micro-porosity might have a profound influence on crack propagation. In osteogenesis imperfecta murine (oim) bones, which represent the moderate to severe condition of osteogenesis imperfecta in humans, a genetic mutation results in high bone fragility. Oim bones have more numerous and branched vascular canals compared to their wild type (WT) controls [1]. The objective of this study is to use the Extended Element Method (XFEM) tools provided by Abaqus (v 6.12) to characterize the role of vascular canals in mouse cortical bone during crack propagation. The topology of transverse cross sections of oim and WT tibial mid-diaphysis were captured with synchrotron radiation-based computed tomography and used to create two-dimensional models. Although XFEM allows modelling crack propagation along an arbitrary, solution-dependent path, there are some limitations when using this technique to model bone at t...

Journal of Bone and Mineral Research, 2014

Journal of the Mechanical Behavior of Biomedical Materials, 2013

Journal of Biomechanics, 2014

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