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Papers by Najib Alidrissi
Informatics for Health and Social Care
Journal of Oncology Research Reviews & Reports, Sep 30, 2022
Through a prospective cohort study we aimed to optimize prevention and management of chemotherapy... more Through a prospective cohort study we aimed to optimize prevention and management of chemotherapy-induced nausea and vomiting (CINV) in the emergence of new therapies for breast cancer patients. We included breast cancer patients treated with moderate emetogenic (MEC) or highly emetogenic chemotherapy (HEC) all stages combined, from April 2021 to November 2021. Patients were required to answer a survey of 32 questions in order to analyze the potential involvement of known and unknown risk factors in the occurrence of CINV. The acute phase of CINV was defined as nausea and vomiting that developed ≤ 24 hours after the start of chemotherapy. Delayed phase of CINV was defined as nausea and vomiting that developed > 24 hours after the start of chemotherapy. The severity of nausea and vomiting was evaluated with common terminology criteria for adverse events (CTCAE) v5.0; publish to date: November 27, 2017. Analysis and results were performed using JAMOVI statistical software. In total, 177 patients received chemotherapy, 103 patients(58%) received (HEC), and 74 patients (42%) received (MEC). All patients were female (100%). Risk factors associated to occurrence of CINV included previously known factors: Younger age than 50 years (29,8%), history of pregnancy-related nausea and vomiting (74,7%), alcohol use (no patient reported previous alcohol consumption), failure to adhere to antiemetic treatment guidelines (9,6%). The compliance with treatment score (90,4%) showed a good commitment of the patients in the process of their medical healthcare. Other potential risk factors have been also explored to determine their involvement or not in the occurrence of CINV (cancer stage, performance status, education level, chemotherapy protocols, the use of traditional herbs known as an antibacterial agent and immunity booster in our context). In the acute phase, (78%) of patients experienced nausea and (47,8%) experienced vomiting. In the delayed phase, (37,1%) of patients experienced nausea and only (15,3%) experienced vomiting. The severity of nausea and vomiting was evaluated according to CTCAE v5.0 in both groups HEC and MEC. Only (8,7%) had to stop treatment for non-tolerance (table 1-2). The present study demonstrated that high compliance to treatment guidelines for CINV and individualized care could lead to more optimal management of CINV.
Cureus
Background Cognitive dysfunction is increasingly recognized as an important comorbidity of diabet... more Background Cognitive dysfunction is increasingly recognized as an important comorbidity of diabetes mellitus (DM). Objective The purpose of this study was to determine the prevalence and predictors of cognitive decline in individuals with type 2 diabetes mellitus (T2DM). Methods This cohort study included patients with type 2 diabetes mellitus aged between 40 and 75 years and with a duration of the evolution of diabetes that is greater than five years admitted in endocrinology consultation of the Sheikh Khalifa ibn Zaid Hospital in Casablanca, Morocco. For each patient, we collected clinical characteristics and biological assessments. All subjects provided screening test results as defined by the Mini-Mental State Examination (MMSE). Results We included a total of 100 patients with diabetes between May and September 2021. The median age of the patients was 65 years (interquartile range (IQR): 59-70 years), 65% were males, and the median duration of diabetes was 15 years (IQR: 9-20 years). The most common cardiovascular risk factors (CVRFs) were hypertension (72.7%) and dyslipidemia (53%). The most common complications of diabetes were peripheral neuropathy (50%), diabetic retinopathy (DR) (39%), peripheral artery disease (33%), and coronary artery disease (27%). Cognitive impairment was present in 47.5% of our patients. For the multivariate analysis, we found that the decrease in the MMSE score is associated with the increase in age (p-value = 0.004) and the occurrence of diabetic retinopathy (p-value < 0.001), dyslipidemia (p-value = 0.006), and elevated creatinine (p-value < 0.001). Conclusion It is necessary to consider the cognitive decline of patients with diabetes as one of the most important complications of this disease because of its impact on the evolution and compliance of these patients.
Cureus
Benameur et al. This is an open access article distributed under the terms of the Creative Common... more Benameur et al. This is an open access article distributed under the terms of the Creative Commons Attribution License CC-BY 4.0., which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Health Sciences, 2021
Introduction: Chondrosarcoma includes several anatomoclinical forms of tumors with cartilaginous ... more Introduction: Chondrosarcoma includes several anatomoclinical forms of tumors with cartilaginous histogenesis.It is a malignant tumor whose tumor cells are associated with a cartilage matrix.Case report: We present the case of a patient with stage 1 chondrosarcoma of the proximal part of the left fibula.The patient underwent a proximal fibula resection with a favorable outcome.Conclusion: Resection of tumors of the proximal fibula may cause knee instability, peroneal palsy through involvement of the external popliteal sciatic nerve or with local radiotherapy, a higher risk of delayed healing and the occurrence of fracture. Despite the risks of resection of the proximal fibula, good functional results can be obtained.
Integrative Journal of Medical Sciences, 2020
The existence of alveolar processes and the integrity of the maxillae outside of a specific patho... more The existence of alveolar processes and the integrity of the maxillae outside of a specific pathological process are linked to the presence of teeth. The aging process is most often accompanied, at the buccal level, by a narrowing of the prosthetic corridor in relation to the importance of bone resorption and the invasion of peripheral elements. Thus, we are and will be confronted more and more with complete edentulous patients, presenting a very strong resorption of the alveolar processes, even of the osseous bases, which will increase proportionally the difficulties of obtaining a good retention and good stability of the prostheses.Our work aims to review the various means available to us to prevent bone resorption, throughout the stages of prosthetic and post-prosthetic realization.
The Pan African medical journal, 2020
Squamous cell carcinoma associated with chronic osteomyelitis is rare. However, it must be suspec... more Squamous cell carcinoma associated with chronic osteomyelitis is rare. However, it must be suspected in patients with modification of common local symptoms. Delayed diagnosis can be fatal. Repeated biopsies can greatly help physicians who treat patients. We report the case of a 47-year-old patient diagnosed with carcinomatous degeneration associated with chronic osteomyelitis fistulized to the skin. Amputation was performed.
We report a case of extraosseous Ewing's sarcoma localized in the gluteal region. The treatme... more We report a case of extraosseous Ewing's sarcoma localized in the gluteal region. The treatment consisted of chemotherapy to reduce tumor size followed by surgery.
We report eight cases of chondromatosis of the knee treated surgically. The aim of our work is to... more We report eight cases of chondromatosis of the knee treated surgically. The aim of our work is to attract the attention of clinicians on the importance of early detection of disease to prevent progression of osteoarthritis. the therapeutic decision was facilitated by the use of the classification of Milgram. We observed superiority of arthroscopy compared to open surgery.
Integrative Journal of Medical Sciences
Introduction: The avulsion fractures of the calcaneal tuberosity represent a rare model of injury... more Introduction: The avulsion fractures of the calcaneal tuberosity represent a rare model of injury that is caused by a powerful tension force of the Achilles tendon associated or not to direct shock to the calcaneusCase report: We report a case of direct trauma to the heel on the edge of the swimming pool at the sport stroke of swimming.Percutaneous reduction by bone reduction forceps under fluoroscopy fluoroscopy with osteosynthesis by two percutaneous cannula screws on Kirchner wires. Equine cast immobilization after removal of the threads. Good clinical and functional radiological evolution.Conclusion: The percutaneous screw under fluoroscopy is the best technique with good results anatomical and functional and aesthetic.
Journal De Traumatologie Du Sport, 2011
The rupture of anterior cruciate ligament (ACL) is the most frequent in modern sport. Our team ha... more The rupture of anterior cruciate ligament (ACL) is the most frequent in modern sport. Our team has adopted a new technique of ACL reconstruction using a single hamstring tendon fixation with a tape locking screw (TLS), which saves bone and tendon, for a possible long-term recovery. The experience of our team in terms of ligament reconstruction is very satisfactory functional
Informatics for Health and Social Care
Journal of Oncology Research Reviews & Reports, Sep 30, 2022
Through a prospective cohort study we aimed to optimize prevention and management of chemotherapy... more Through a prospective cohort study we aimed to optimize prevention and management of chemotherapy-induced nausea and vomiting (CINV) in the emergence of new therapies for breast cancer patients. We included breast cancer patients treated with moderate emetogenic (MEC) or highly emetogenic chemotherapy (HEC) all stages combined, from April 2021 to November 2021. Patients were required to answer a survey of 32 questions in order to analyze the potential involvement of known and unknown risk factors in the occurrence of CINV. The acute phase of CINV was defined as nausea and vomiting that developed ≤ 24 hours after the start of chemotherapy. Delayed phase of CINV was defined as nausea and vomiting that developed > 24 hours after the start of chemotherapy. The severity of nausea and vomiting was evaluated with common terminology criteria for adverse events (CTCAE) v5.0; publish to date: November 27, 2017. Analysis and results were performed using JAMOVI statistical software. In total, 177 patients received chemotherapy, 103 patients(58%) received (HEC), and 74 patients (42%) received (MEC). All patients were female (100%). Risk factors associated to occurrence of CINV included previously known factors: Younger age than 50 years (29,8%), history of pregnancy-related nausea and vomiting (74,7%), alcohol use (no patient reported previous alcohol consumption), failure to adhere to antiemetic treatment guidelines (9,6%). The compliance with treatment score (90,4%) showed a good commitment of the patients in the process of their medical healthcare. Other potential risk factors have been also explored to determine their involvement or not in the occurrence of CINV (cancer stage, performance status, education level, chemotherapy protocols, the use of traditional herbs known as an antibacterial agent and immunity booster in our context). In the acute phase, (78%) of patients experienced nausea and (47,8%) experienced vomiting. In the delayed phase, (37,1%) of patients experienced nausea and only (15,3%) experienced vomiting. The severity of nausea and vomiting was evaluated according to CTCAE v5.0 in both groups HEC and MEC. Only (8,7%) had to stop treatment for non-tolerance (table 1-2). The present study demonstrated that high compliance to treatment guidelines for CINV and individualized care could lead to more optimal management of CINV.
Cureus
Background Cognitive dysfunction is increasingly recognized as an important comorbidity of diabet... more Background Cognitive dysfunction is increasingly recognized as an important comorbidity of diabetes mellitus (DM). Objective The purpose of this study was to determine the prevalence and predictors of cognitive decline in individuals with type 2 diabetes mellitus (T2DM). Methods This cohort study included patients with type 2 diabetes mellitus aged between 40 and 75 years and with a duration of the evolution of diabetes that is greater than five years admitted in endocrinology consultation of the Sheikh Khalifa ibn Zaid Hospital in Casablanca, Morocco. For each patient, we collected clinical characteristics and biological assessments. All subjects provided screening test results as defined by the Mini-Mental State Examination (MMSE). Results We included a total of 100 patients with diabetes between May and September 2021. The median age of the patients was 65 years (interquartile range (IQR): 59-70 years), 65% were males, and the median duration of diabetes was 15 years (IQR: 9-20 years). The most common cardiovascular risk factors (CVRFs) were hypertension (72.7%) and dyslipidemia (53%). The most common complications of diabetes were peripheral neuropathy (50%), diabetic retinopathy (DR) (39%), peripheral artery disease (33%), and coronary artery disease (27%). Cognitive impairment was present in 47.5% of our patients. For the multivariate analysis, we found that the decrease in the MMSE score is associated with the increase in age (p-value = 0.004) and the occurrence of diabetic retinopathy (p-value < 0.001), dyslipidemia (p-value = 0.006), and elevated creatinine (p-value < 0.001). Conclusion It is necessary to consider the cognitive decline of patients with diabetes as one of the most important complications of this disease because of its impact on the evolution and compliance of these patients.
Cureus
Benameur et al. This is an open access article distributed under the terms of the Creative Common... more Benameur et al. This is an open access article distributed under the terms of the Creative Commons Attribution License CC-BY 4.0., which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Health Sciences, 2021
Introduction: Chondrosarcoma includes several anatomoclinical forms of tumors with cartilaginous ... more Introduction: Chondrosarcoma includes several anatomoclinical forms of tumors with cartilaginous histogenesis.It is a malignant tumor whose tumor cells are associated with a cartilage matrix.Case report: We present the case of a patient with stage 1 chondrosarcoma of the proximal part of the left fibula.The patient underwent a proximal fibula resection with a favorable outcome.Conclusion: Resection of tumors of the proximal fibula may cause knee instability, peroneal palsy through involvement of the external popliteal sciatic nerve or with local radiotherapy, a higher risk of delayed healing and the occurrence of fracture. Despite the risks of resection of the proximal fibula, good functional results can be obtained.
Integrative Journal of Medical Sciences, 2020
The existence of alveolar processes and the integrity of the maxillae outside of a specific patho... more The existence of alveolar processes and the integrity of the maxillae outside of a specific pathological process are linked to the presence of teeth. The aging process is most often accompanied, at the buccal level, by a narrowing of the prosthetic corridor in relation to the importance of bone resorption and the invasion of peripheral elements. Thus, we are and will be confronted more and more with complete edentulous patients, presenting a very strong resorption of the alveolar processes, even of the osseous bases, which will increase proportionally the difficulties of obtaining a good retention and good stability of the prostheses.Our work aims to review the various means available to us to prevent bone resorption, throughout the stages of prosthetic and post-prosthetic realization.
The Pan African medical journal, 2020
Squamous cell carcinoma associated with chronic osteomyelitis is rare. However, it must be suspec... more Squamous cell carcinoma associated with chronic osteomyelitis is rare. However, it must be suspected in patients with modification of common local symptoms. Delayed diagnosis can be fatal. Repeated biopsies can greatly help physicians who treat patients. We report the case of a 47-year-old patient diagnosed with carcinomatous degeneration associated with chronic osteomyelitis fistulized to the skin. Amputation was performed.
We report a case of extraosseous Ewing's sarcoma localized in the gluteal region. The treatme... more We report a case of extraosseous Ewing's sarcoma localized in the gluteal region. The treatment consisted of chemotherapy to reduce tumor size followed by surgery.
We report eight cases of chondromatosis of the knee treated surgically. The aim of our work is to... more We report eight cases of chondromatosis of the knee treated surgically. The aim of our work is to attract the attention of clinicians on the importance of early detection of disease to prevent progression of osteoarthritis. the therapeutic decision was facilitated by the use of the classification of Milgram. We observed superiority of arthroscopy compared to open surgery.
Integrative Journal of Medical Sciences
Introduction: The avulsion fractures of the calcaneal tuberosity represent a rare model of injury... more Introduction: The avulsion fractures of the calcaneal tuberosity represent a rare model of injury that is caused by a powerful tension force of the Achilles tendon associated or not to direct shock to the calcaneusCase report: We report a case of direct trauma to the heel on the edge of the swimming pool at the sport stroke of swimming.Percutaneous reduction by bone reduction forceps under fluoroscopy fluoroscopy with osteosynthesis by two percutaneous cannula screws on Kirchner wires. Equine cast immobilization after removal of the threads. Good clinical and functional radiological evolution.Conclusion: The percutaneous screw under fluoroscopy is the best technique with good results anatomical and functional and aesthetic.
Journal De Traumatologie Du Sport, 2011
The rupture of anterior cruciate ligament (ACL) is the most frequent in modern sport. Our team ha... more The rupture of anterior cruciate ligament (ACL) is the most frequent in modern sport. Our team has adopted a new technique of ACL reconstruction using a single hamstring tendon fixation with a tape locking screw (TLS), which saves bone and tendon, for a possible long-term recovery. The experience of our team in terms of ligament reconstruction is very satisfactory functional