Nancy Nishimura - Academia.edu (original) (raw)

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Papers by Nancy Nishimura

Research paper thumbnail of Acute inflammatory response in the stomach of BALB/c mice challenged with coccoidal Helicobacter pylori

Memórias do Instituto …, 2002

Research paper thumbnail of Progression of liver fibrosis in blood donors infected with hepatitis C virus

Romanian journal of gastroenterology, 2004

Chronic hepatitis by HCV is progressive towards cirrhosis, with variable rate. We evaluated the r... more Chronic hepatitis by HCV is progressive towards cirrhosis, with variable rate. We evaluated the rate of fibrosis progression (RFP), risk factors associated with advanced fibrosis (F3 and F4), and estimated the evolution time to cirrhosis. We transversely selected 142 blood donors infected only with HCV, with a known route of infection, submitted to liver biopsy at admission. RFP= ratio between stage of fibrosis (METAVIR)/estimated duration of infection in years. Non-parametric tests and logistic regression analysis, with significance level of 5% were used. Median RFP was 0.086 U/year (0.05-0.142). Ten patients had F4 and 25 had F3. Median RFP values were significantly different (p=0.001) from one age group at contamination to the others and ALT and AST levels. There were no differences in the expected evolution to cirrhosis between intermediate fibrosers (F2) and the rapid fibrosers (F3 and F4). The independent variables associated with advanced fibrosis were ALT (OR 7.2) and GGT (O...

Research paper thumbnail of Acute inflammatory response in the stomach of BALB/c mice challenged with coccoidal Helicobacter pylori

Memórias do Instituto …, 2002

Research paper thumbnail of Progression of liver fibrosis in blood donors infected with hepatitis C virus

Romanian journal of gastroenterology, 2004

Chronic hepatitis by HCV is progressive towards cirrhosis, with variable rate. We evaluated the r... more Chronic hepatitis by HCV is progressive towards cirrhosis, with variable rate. We evaluated the rate of fibrosis progression (RFP), risk factors associated with advanced fibrosis (F3 and F4), and estimated the evolution time to cirrhosis. We transversely selected 142 blood donors infected only with HCV, with a known route of infection, submitted to liver biopsy at admission. RFP= ratio between stage of fibrosis (METAVIR)/estimated duration of infection in years. Non-parametric tests and logistic regression analysis, with significance level of 5% were used. Median RFP was 0.086 U/year (0.05-0.142). Ten patients had F4 and 25 had F3. Median RFP values were significantly different (p=0.001) from one age group at contamination to the others and ALT and AST levels. There were no differences in the expected evolution to cirrhosis between intermediate fibrosers (F2) and the rapid fibrosers (F3 and F4). The independent variables associated with advanced fibrosis were ALT (OR 7.2) and GGT (O...

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