Nanda Rezita - Academia.edu (original) (raw)

Papers by Nanda Rezita

Journal of Islamic Pharmacy

Vaginal discharge is one of the most common reproductive health problems experienced by women, in... more Vaginal discharge is one of the most common reproductive health problems experienced by women, in overcoming this it is necessary to use soap female cleansing (feminine hygiene). Candida albicans can be said as the main causative agent of vaginal discharge. This research aims to get a liquid soap formula for female cleansing (feminine hygiene) ethanol extract of ceremai leaf (Phyllanthus acidus (L.) Skeels) the best, in terms of terms of stability, comfort, and effectiveness of antifungal against Candida albicans, with variations in the concentration of the ethanol extract of ceremai leaf (Phyllanthus acidus (L.) Skeels) of 42.8%, 50% and 57.1%. In this study, ceremai leaf powder (Phyllanthus acidus (L.) Skeels) was extracted by maceration method using 96% ethanol and obtained a thick extract of 86.2 grams. Ethanol extract of ceremai leaf (Phyllanthus acidus (L.) Skeels) has the activity of antifungal compounds are thought to be from secondary metabolites, namely the group of compounds flavonoids, tannins, saponins, and alkaloids. Female cleansing liquid soap (feminine hygiene) ethanol extract of ceremai (Phyllanthus acidus (L.) Skeels) leaf tested for physical stability using the cycling test method, the results obtained organoleptically unstable due to changes in shape and odor cycle-1 to cycle-6, then test the pH, homogeneity, foam height, irritation, viscosity, and the water content is in accordance with the literature, while some are not in accordance with the literature, namely foam height test F1 cycle-1, F2 cycle-0, F3 cycle-2, cycle-4, and cycle-5, as well as viscosity test F1 cycle-6, and F2 cycle-6. Effectiveness test against Candida albicans fungal using the well diffusion method, the results obtained are F1 of 5.24 mm, F2 of 9.18 mm, and F3 of 9.24 mm. So that it can concluded that F1, F2, and F3 were less effective in inhibiting Candida albicans.

Journal of Islamic Pharmacy

Vaginal discharge is one of the most common reproductive health problems experienced by women, in... more Vaginal discharge is one of the most common reproductive health problems experienced by women, in overcoming this it is necessary to use soap female cleansing (feminine hygiene). Candida albicans can be said as the main causative agent of vaginal discharge. This research aims to get a liquid soap formula for female cleansing (feminine hygiene) ethanol extract of ceremai leaf (Phyllanthus acidus (L.) Skeels) the best, in terms of terms of stability, comfort, and effectiveness of antifungal against Candida albicans, with variations in the concentration of the ethanol extract of ceremai leaf (Phyllanthus acidus (L.) Skeels) of 42.8%, 50% and 57.1%. In this study, ceremai leaf powder (Phyllanthus acidus (L.) Skeels) was extracted by maceration method using 96% ethanol and obtained a thick extract of 86.2 grams. Ethanol extract of ceremai leaf (Phyllanthus acidus (L.) Skeels) has the activity of antifungal compounds are thought to be from secondary metabolites, namely the group of compounds flavonoids, tannins, saponins, and alkaloids. Female cleansing liquid soap (feminine hygiene) ethanol extract of ceremai (Phyllanthus acidus (L.) Skeels) leaf tested for physical stability using the cycling test method, the results obtained organoleptically unstable due to changes in shape and odor cycle-1 to cycle-6, then test the pH, homogeneity, foam height, irritation, viscosity, and the water content is in accordance with the literature, while some are not in accordance with the literature, namely foam height test F1 cycle-1, F2 cycle-0, F3 cycle-2, cycle-4, and cycle-5, as well as viscosity test F1 cycle-6, and F2 cycle-6. Effectiveness test against Candida albicans fungal using the well diffusion method, the results obtained are F1 of 5.24 mm, F2 of 9.18 mm, and F3 of 9.24 mm. So that it can concluded that F1, F2, and F3 were less effective in inhibiting Candida albicans.