Nayef Chahin - Academia.edu (original) (raw)

Papers by Nayef Chahin

Research paper thumbnail of Successes of a Focused Mothers' Own Milk (MOM) Program in Counteracting Unintended Effects of a Donor Milk Program on MOM Rates at Discharge

Breastfeeding Medicine, Nov 30, 2023

Research paper thumbnail of Lactation Support as a Proxy Measure of Family-Centered Care Quality in Neonates with Life-Limiting Conditions—A Comparative Study

Children

Background: Lactation support is an important measure of Family-Centered Care (FCC) in the Neonat... more Background: Lactation support is an important measure of Family-Centered Care (FCC) in the Neonatal Intensive Care Unit (NICU). Life-limiting conditions (LLCs) raise complex ethical care issues for providers and parents in the NICU and represent a key and often overlooked population for whom FCC is particularly important. We investigated healthcare disparities in FCC lactation support quality in infants with LLCs. Methods: A retrospective cohort of inborn infants with or without LLCs admitted to the NICU between 2015–2023 included 395 infants with 219 LLC infants and 176 matched non-LLC infants and were compared on LLC supports. Results: The LLC cohort experienced greater skin-to-skin support, but less lactation specialist visits, breast pumps provided, and human milk oral care use. LLC infants also experienced less maternal visitation, use of donor milk (LLC: 15.5%, non-LLC: 33.5%), and breastfeeds (LLC: 24.2%, non-LLC: 43.2%), with lower mean human milk provision (LLC: 36.6%, non-...

Research paper thumbnail of Publisher Correction: Predictors of circuit health in neonatal patients receiving extracorporeal membrane oxygenation (ECMO)

Scientific Reports, Feb 14, 2022

Research paper thumbnail of Fenton vs. Intergrowth-21st: Postnatal Growth Assessment and Prediction of Neurodevelopment in Preterm Infants

Nutrients, Aug 18, 2021

This article is an open access article distributed under the terms and conditions of the Creative... more This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY

Research paper thumbnail of Ascorbic Acid and the Premature Infant

Nutrients

Little information exists about the plasma target nutritional needs of the >15 million prematu... more Little information exists about the plasma target nutritional needs of the >15 million premature infants <37 weeks gestation. Investigating ascorbic acid’s (AscA) role in infant health, our study details the relationship of infant characteristics and maternal health on infant plasma AscA level (pAscA) during postnatal development. Furthermore, we determined pAscA influence during the first week of life (EpAscA) with later infant morbidities. We hypothesize that pAscA is influenced by gestational organ immaturity, as well as maternal factors, with EpAscA associated with greater morbidity risk. We conducted a prospective longitudinal observational study of pAscA, demographics and hospital course detailed in infants ≤34 weeks. Sixty-three subjects were included, with >200 urine and plasma data points analyzed. Maternal smoking, exposure to magnesium sulfate (MgSO4) and advancing gestational and postnatal age were associated with lower pAscA. Non-white infants and those ≤30 wee...

Research paper thumbnail of Fenton vs. Intergrowth-21st: Postnatal Growth Assessment and Prediction of Neurodevelopment in Preterm Infants

Nutrients

Although the survival rate of preterm infants has improved over the years, growth failure and ass... more Although the survival rate of preterm infants has improved over the years, growth failure and associated impaired neurodevelopmental outcome remains a significant morbidity. Optimal nutrition plays an important role in achieving adequate postnatal growth. Accurate growth monitoring of preterm infants is critical in guiding nutritional protocols. Currently, there is no consensus regarding which growth assessment tool is suitable for monitoring postnatal growth of preterm infants to foster optimal neurodevelopmental outcomes while avoiding future consequences of aggressive nutritional approaches including increased risk for cardiovascular disease and metabolic syndrome. A retrospective single center cohort study was conducted to compare the performance of two growth-assessment tools, Fenton and Intergrowth-21st (IG-21st) in the classification of size at birth, identification of impaired growth and predicting neurodevelopment. A total of 340 infants with mean gestational age of 30 week...

Research paper thumbnail of 475: Video Versus Mannequin Training as a Teaching Tool for Pediatric Advanced Airway Management

Critical Care Medicine, 2013

Introduction: Airway management is one the cornerstone of critical care management and is an impo... more Introduction: Airway management is one the cornerstone of critical care management and is an important component of all life saving maneuvers in a crisis situation. The primary goal of this study is to determine the best modality for teaching advance management skills to novices in airway management. Several modalities are used to teach advanced airway management. Audio visual tools and high fidelity simulators are common modalities used for this purpose. We compare the performance of novice participants in both video and mannequin training to assess the psychomotor skills required in advanced pediatric airway management. Methods: The subjects for this study have no prior pediatric advanced airway management skills. The participants were recruited from a pool of third and fourth year medical students after obtaining Institutional Review Board approval and informed consent. Any candidate with prior exposure to airway training or courses similar to PALS or ACLS were excluded. Thirty p...

Research paper thumbnail of 852: Appraisal of Pediatric Critical Care for Northwestern Nigeria

Critical Care Medicine, 2014

Research paper thumbnail of New modes of surfactant delivery

Paediatric Respiratory Reviews, 2021

The provision of exogenous surfactant to premature infants with respiratory distress syndrome has... more The provision of exogenous surfactant to premature infants with respiratory distress syndrome has revolutionized the way we care for these patients, significantly improving survival and decreasing morbidity. Currently, the Intubate-SURfactant-Extubate (INSURE) to non-invasive ventilation method remains the standard method for surfactant delivery in the United States. However, the INSURE method requires intubation via direct visualization with a laryngoscope and possible need for sedation. Both carry significant risk to the patients, prompting the development of less invasive ways of safely and efficaciously providing surfactant to newborn infants. The present article reviews and describes the benefits and limitations of several of these alternative methods, including Less Invasive Surfactant Administration (LISA), Minimally Invasive Surfactant Therapy (MIST), via aerosolization, laryngeal mask airway (LMA), and direct nasopharyngeal deposition, focusing on assessment of clinical benefits and the level/risk of invasiveness.

Research paper thumbnail of Publisher Correction: Predictors of circuit health in neonatal patients receiving extracorporeal membrane oxygenation (ECMO)

Research paper thumbnail of Predictors of circuit health in neonatal patients receiving extracorporeal membrane oxygenation (ECMO)

Scientific Reports

To identify predictors of neonatal ECMO circuit health, a retrospective analysis of circuit funct... more To identify predictors of neonatal ECMO circuit health, a retrospective analysis of circuit functional pressure and flow parameters as well as infant clotting values were collected 48 h prior to and 24 h post circuit change. Circuit impairment was defined as need for partial or total circuit change. Statistical analysis used multivariate statistics and non-parametric Mann–Whitney U-test with possible non-normality of measurements. A total of 9764 ECMO circuit and clotting values in 21 circuits were analyzed. Circuit delta-P mean, and maximum values increased from 8.62 to 48.59 mmHg (p < 0.011) and 16.00 to 53.00 mmHg (p < 0.0128) respectively prior to need for circuit change. Maximum and mean Pump Flow Revolutions per minute (RPM) increased by 75% (p < 0.0043) and 81% (p < 0.0057), respectively. Mean plasma free hemoglobin (pfHb) increased from 26.45 to 76.00 mg/dl, (p < 0.0209). Sweep, venous pressure, and clotting parameters were unaffected. ECMO circuit delta-P, RP...

Research paper thumbnail of Successes of a Focused Mothers' Own Milk (MOM) Program in Counteracting Unintended Effects of a Donor Milk Program on MOM Rates at Discharge

Breastfeeding Medicine, Nov 30, 2023

Research paper thumbnail of Lactation Support as a Proxy Measure of Family-Centered Care Quality in Neonates with Life-Limiting Conditions—A Comparative Study

Children

Background: Lactation support is an important measure of Family-Centered Care (FCC) in the Neonat... more Background: Lactation support is an important measure of Family-Centered Care (FCC) in the Neonatal Intensive Care Unit (NICU). Life-limiting conditions (LLCs) raise complex ethical care issues for providers and parents in the NICU and represent a key and often overlooked population for whom FCC is particularly important. We investigated healthcare disparities in FCC lactation support quality in infants with LLCs. Methods: A retrospective cohort of inborn infants with or without LLCs admitted to the NICU between 2015–2023 included 395 infants with 219 LLC infants and 176 matched non-LLC infants and were compared on LLC supports. Results: The LLC cohort experienced greater skin-to-skin support, but less lactation specialist visits, breast pumps provided, and human milk oral care use. LLC infants also experienced less maternal visitation, use of donor milk (LLC: 15.5%, non-LLC: 33.5%), and breastfeeds (LLC: 24.2%, non-LLC: 43.2%), with lower mean human milk provision (LLC: 36.6%, non-...

Research paper thumbnail of Publisher Correction: Predictors of circuit health in neonatal patients receiving extracorporeal membrane oxygenation (ECMO)

Scientific Reports, Feb 14, 2022

Research paper thumbnail of Fenton vs. Intergrowth-21st: Postnatal Growth Assessment and Prediction of Neurodevelopment in Preterm Infants

Nutrients, Aug 18, 2021

This article is an open access article distributed under the terms and conditions of the Creative... more This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY

Research paper thumbnail of Ascorbic Acid and the Premature Infant

Nutrients

Little information exists about the plasma target nutritional needs of the >15 million prematu... more Little information exists about the plasma target nutritional needs of the >15 million premature infants <37 weeks gestation. Investigating ascorbic acid’s (AscA) role in infant health, our study details the relationship of infant characteristics and maternal health on infant plasma AscA level (pAscA) during postnatal development. Furthermore, we determined pAscA influence during the first week of life (EpAscA) with later infant morbidities. We hypothesize that pAscA is influenced by gestational organ immaturity, as well as maternal factors, with EpAscA associated with greater morbidity risk. We conducted a prospective longitudinal observational study of pAscA, demographics and hospital course detailed in infants ≤34 weeks. Sixty-three subjects were included, with >200 urine and plasma data points analyzed. Maternal smoking, exposure to magnesium sulfate (MgSO4) and advancing gestational and postnatal age were associated with lower pAscA. Non-white infants and those ≤30 wee...

Research paper thumbnail of Fenton vs. Intergrowth-21st: Postnatal Growth Assessment and Prediction of Neurodevelopment in Preterm Infants

Nutrients

Although the survival rate of preterm infants has improved over the years, growth failure and ass... more Although the survival rate of preterm infants has improved over the years, growth failure and associated impaired neurodevelopmental outcome remains a significant morbidity. Optimal nutrition plays an important role in achieving adequate postnatal growth. Accurate growth monitoring of preterm infants is critical in guiding nutritional protocols. Currently, there is no consensus regarding which growth assessment tool is suitable for monitoring postnatal growth of preterm infants to foster optimal neurodevelopmental outcomes while avoiding future consequences of aggressive nutritional approaches including increased risk for cardiovascular disease and metabolic syndrome. A retrospective single center cohort study was conducted to compare the performance of two growth-assessment tools, Fenton and Intergrowth-21st (IG-21st) in the classification of size at birth, identification of impaired growth and predicting neurodevelopment. A total of 340 infants with mean gestational age of 30 week...

Research paper thumbnail of 475: Video Versus Mannequin Training as a Teaching Tool for Pediatric Advanced Airway Management

Critical Care Medicine, 2013

Introduction: Airway management is one the cornerstone of critical care management and is an impo... more Introduction: Airway management is one the cornerstone of critical care management and is an important component of all life saving maneuvers in a crisis situation. The primary goal of this study is to determine the best modality for teaching advance management skills to novices in airway management. Several modalities are used to teach advanced airway management. Audio visual tools and high fidelity simulators are common modalities used for this purpose. We compare the performance of novice participants in both video and mannequin training to assess the psychomotor skills required in advanced pediatric airway management. Methods: The subjects for this study have no prior pediatric advanced airway management skills. The participants were recruited from a pool of third and fourth year medical students after obtaining Institutional Review Board approval and informed consent. Any candidate with prior exposure to airway training or courses similar to PALS or ACLS were excluded. Thirty p...

Research paper thumbnail of 852: Appraisal of Pediatric Critical Care for Northwestern Nigeria

Critical Care Medicine, 2014

Research paper thumbnail of New modes of surfactant delivery

Paediatric Respiratory Reviews, 2021

The provision of exogenous surfactant to premature infants with respiratory distress syndrome has... more The provision of exogenous surfactant to premature infants with respiratory distress syndrome has revolutionized the way we care for these patients, significantly improving survival and decreasing morbidity. Currently, the Intubate-SURfactant-Extubate (INSURE) to non-invasive ventilation method remains the standard method for surfactant delivery in the United States. However, the INSURE method requires intubation via direct visualization with a laryngoscope and possible need for sedation. Both carry significant risk to the patients, prompting the development of less invasive ways of safely and efficaciously providing surfactant to newborn infants. The present article reviews and describes the benefits and limitations of several of these alternative methods, including Less Invasive Surfactant Administration (LISA), Minimally Invasive Surfactant Therapy (MIST), via aerosolization, laryngeal mask airway (LMA), and direct nasopharyngeal deposition, focusing on assessment of clinical benefits and the level/risk of invasiveness.

Research paper thumbnail of Publisher Correction: Predictors of circuit health in neonatal patients receiving extracorporeal membrane oxygenation (ECMO)

Research paper thumbnail of Predictors of circuit health in neonatal patients receiving extracorporeal membrane oxygenation (ECMO)

Scientific Reports

To identify predictors of neonatal ECMO circuit health, a retrospective analysis of circuit funct... more To identify predictors of neonatal ECMO circuit health, a retrospective analysis of circuit functional pressure and flow parameters as well as infant clotting values were collected 48 h prior to and 24 h post circuit change. Circuit impairment was defined as need for partial or total circuit change. Statistical analysis used multivariate statistics and non-parametric Mann–Whitney U-test with possible non-normality of measurements. A total of 9764 ECMO circuit and clotting values in 21 circuits were analyzed. Circuit delta-P mean, and maximum values increased from 8.62 to 48.59 mmHg (p < 0.011) and 16.00 to 53.00 mmHg (p < 0.0128) respectively prior to need for circuit change. Maximum and mean Pump Flow Revolutions per minute (RPM) increased by 75% (p < 0.0043) and 81% (p < 0.0057), respectively. Mean plasma free hemoglobin (pfHb) increased from 26.45 to 76.00 mg/dl, (p < 0.0209). Sweep, venous pressure, and clotting parameters were unaffected. ECMO circuit delta-P, RP...