Ngoc Le - Academia.edu (original) (raw)
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Papers by Ngoc Le
ACS Applied Bio Materials, 2020
This study represents a successful approach towards employing polycaprolactonepolyamidoamine (PCL... more This study represents a successful approach towards employing polycaprolactonepolyamidoamine (PCL-PAMAM) linear dendritic block copolymer (LDBC) nanoparticles as small molecule carriers in NIR imaging and photothermal therapy. A feasible and robust synthetic strategy was used to synthesize a library of amphiphilic LDBCs with well-controlled hydrophobic to hydrophilic weight ratios. Systems with hydrophobic weight ratio higher than 70%, formed nanoparticles in aqueous media, which show hydrodynamic diameters of 51.6 and 96.4 nm. These nanoparticles exhibited loading efficiencies up to 21% for a hydrophobic molecule and 64% for a hydrophilic molecule. Furthermore, successful cellular uptake was observed via trafficking into endosomal and lysosomal compartments with an encapsulated NIR theranostic agent (C3) without inducing cell death. A preliminary photothermal assessment resulted in cell death after treating the cells with encapsulated C3 and exposing them to NIR light. The results of this work confirm the potential of these polymeric materials as promising candidates in theranostic nanomedicine. Supporting Information. Supporting materials contain experimental details regarding synthesis, thermal analysis, optical spectra, biological images, and other supplementary results. This material is available free of charge via the Internet at http://pubs.acs.org.) AUTHOR INFORMATION
Tạp chí Phát triển Khoa học và Công nghệ, 2007
... Rayleigh Fading Coded Uncode Coded Uncoded Hình 5 Đồ thị BER cho kênh CDMA có nhiễu và fading... more ... Rayleigh Fading Coded Uncode Coded Uncoded Hình 5 Đồ thị BER cho kênh CDMA có nhiễu và fading khi không có mã hoá kênh Turbo Rayleigh Fading Rayleigh Fading AWGN AWGN Page 6. ... Qua đó, đề ra các giải pháp để năng cao hiệu suất tính toán, giảm độ trễ,vv ...
ACS Applied Bio Materials, 2020
This study represents a successful approach towards employing polycaprolactonepolyamidoamine (PCL... more This study represents a successful approach towards employing polycaprolactonepolyamidoamine (PCL-PAMAM) linear dendritic block copolymer (LDBC) nanoparticles as small molecule carriers in NIR imaging and photothermal therapy. A feasible and robust synthetic strategy was used to synthesize a library of amphiphilic LDBCs with well-controlled hydrophobic to hydrophilic weight ratios. Systems with hydrophobic weight ratio higher than 70%, formed nanoparticles in aqueous media, which show hydrodynamic diameters of 51.6 and 96.4 nm. These nanoparticles exhibited loading efficiencies up to 21% for a hydrophobic molecule and 64% for a hydrophilic molecule. Furthermore, successful cellular uptake was observed via trafficking into endosomal and lysosomal compartments with an encapsulated NIR theranostic agent (C3) without inducing cell death. A preliminary photothermal assessment resulted in cell death after treating the cells with encapsulated C3 and exposing them to NIR light. The results of this work confirm the potential of these polymeric materials as promising candidates in theranostic nanomedicine. Supporting Information. Supporting materials contain experimental details regarding synthesis, thermal analysis, optical spectra, biological images, and other supplementary results. This material is available free of charge via the Internet at http://pubs.acs.org.) AUTHOR INFORMATION
Tạp chí Phát triển Khoa học và Công nghệ, 2007
... Rayleigh Fading Coded Uncode Coded Uncoded Hình 5 Đồ thị BER cho kênh CDMA có nhiễu và fading... more ... Rayleigh Fading Coded Uncode Coded Uncoded Hình 5 Đồ thị BER cho kênh CDMA có nhiễu và fading khi không có mã hoá kênh Turbo Rayleigh Fading Rayleigh Fading AWGN AWGN Page 6. ... Qua đó, đề ra các giải pháp để năng cao hiệu suất tính toán, giảm độ trễ,vv ...