Niaz Hussain - Academia.edu (original) (raw)

Papers by Niaz Hussain

Journal of the College of Physicians and Surgeons, 2009

A young man aged 22 years presented with shortness of breath, left sided chest pain, mild dry cou... more A young man aged 22 years presented with shortness of breath, left sided chest pain, mild dry cough, peripheral cyanosis, fever and generalized weakness for three years. He was diagnosed as having a large infected cystic mediastinal mass with tricuspid regurgitation and severe pulmonary hypertension. On thoracotomy, one litre of pus was aspirated and tumour was excised and sent for histopathology. Biopsy report revealed benign cystic teratoma. This case is reported to highlight the management of a huge infected benign cystic teratoma which is rarely found.

A 16 year old female presented with complain of fever, shortness of breath and upper abdominal pa... more A 16 year old female presented with complain of fever, shortness of breath and upper abdominal pain. Investigation and clinical examination suggestive of empyema thoracis. At thoracotomy Margagni's hernia was found. The purpose of this case report is to highlight the incidental diagnosis of Morgagni's hernia presenting as a thoracic mass in a patient with empyema thoracis. The rationale behind reporting this case is to create educational awareness regarding the rarity of this hernia and its associated presentation with empyema thoracis, both of which were managed surgically during a single procedure

Journal of the College of Physicians and Surgeons--Pakistan : JCPSP, 2009

OBJECTIVE To determine the frequency of survival in patients with thoracic trauma, undergoing Urg... more OBJECTIVE To determine the frequency of survival in patients with thoracic trauma, undergoing Urgent Thoracotomy (UT). STUDY DESIGN Quasi-experimental study. PLACE AND DURATION OF STUDY The study was carried out in the Department of Thoracic Surgery, JPMC, Karachi, from January 2005 to June 2007 (30 months). METHODOLOGY Fifty two patients, who presented with chest trauma and underwent UT within 48 hours of sustaining thoracic trauma, were included in the study. All patients were assessed by history, physical examination and relevant investigations. RESULTS A total of 475 patients with acute thoracic trauma needing admission during the study period presented to the Accidents and Emergency Department. Fifty-two (52/475; 10.9%) patients were indicated for UT. The most common indication for UT was massive hemothorax (43/52; 82.6%). The mean age of the patients was 34.36 +/- 11.02 years. There were 22 (42.2%) blunt injuries and 30 (57.8%) penetrating injuries. Road Traffic Accidents (RTA...

A 20-year-old female presented with complaints of right-sided chest pain, cough, fever and shortn... more A 20-year-old female presented with complaints of right-sided chest pain, cough, fever and shortness of breath for the preceding one-and-a-half year. Air entry was decreased over the middle and lower chest. Computed tomography scan of the chest revealed a cystic lesion with thick margins present in the right hemi-thorax. The cyst was excised by posterolateral thoracotomy. Histopathology revealed it to be mediastinal enteric cyst with intestinal and pancreatic tissue.

Morgagni's hernia

Journal of the College of Physicians and Surgeons--Pakistan : JCPSP, 2008

Morgagni's hernia is an uncommon type of diaphragmatic hernia. These patients usually present... more Morgagni's hernia is an uncommon type of diaphragmatic hernia. These patients usually present in childhood but sometimes later in life. We report a case of 75 years old female who presented with epigastric discomfort and vomiting. She was diagnosed as a case of calculous cholecystitis and was treated with antibiotics but was not relieved. Further investigations revealed Morgagni's hernia. She was successfully managed by open surgical technique.

A 28 year old female presented with the complaint of painful chest wall swelling on the left side... more A 28 year old female presented with the complaint of painful chest wall swelling on the left side anteriorolaterally, for the past three years. Her Trucut biopsy was inconclusive. Incisional biopsy proved it to be aneurysmal bone cyst. It was excised and chest wall was reconstructed with propylene mesh and muscle flaps. Her postoperative recovery was smooth.

JPMA. The Journal of the Pakistan Medical Association, 2014

Fifty-one (51) adult patients more than 12 years of age and either sex with unilateral PA were in... more Fifty-one (51) adult patients more than 12 years of age and either sex with unilateral PA were included in this study. Patients were divided into two groups: A (simple ABSTRACT Objective: To compare the clinical presentation and results of pulmonary resection in simple and complex aspergilloma of the lung.

Journal of the College of …, 2009

OBJECTIVE: To determine the frequency of survival in patients with thoracic trauma, undergoing Ur... more OBJECTIVE: To determine the frequency of survival in patients with thoracic trauma, undergoing Urgent Thoracotomy (UT). STUDY DESIGN: Quasi-experimental study. PLACE AND DURATION OF STUDY: The study was carried out in the Department of Thoracic Surgery, JPMC, ...

JPMA. The Journal of the Pakistan Medical Association, 2010

To determine the outcome of thymectomy in patients with myasthenia gravis and safety of median st... more To determine the outcome of thymectomy in patients with myasthenia gravis and safety of median sternotomy approach. An observational descriptive study was conducted in the department of thoracic surgery JPMC from February 2005 to January 2009. Twenty-two patients having persistent generalized or ocular myasthenia gravis referred to our department by neurologists and general physicians, partially or not responding to medical treatment with or without thymoma, were included in the study. Those who were not fit for anaesthesia were excluded. Preoperatively 2 to 3 sessions of plasmapheresis were done and each patient was given anti myasthenia gravis treatment. Clinical staging was done by Modified Osserman classification. Median sternotomy approach was used. Outcome was assessed on the basis of remission of disease in different Osserman groups. All patients were followed for a minimum of 6 months. Out of 22 patients, 16 (72.7%) were females and 6 (27.2%) males. Mean age at presentation ...

Perforation Operation Interval as Aprognostic Factor in Typhoid Ilealperforation

Pakistan Journal of Chest Medicine, May 23, 2015

BACKGROUND: Rapid, reliable, economical methods are required for diagnosis of tuberculosis. The M... more BACKGROUND: Rapid, reliable, economical methods are required for diagnosis of tuberculosis. The Microscopic Observation of Drug Susceptibility (MODS) assay is a relatively low-cost and simple liquid culture method. The objective of this study is to determine the sensitivity and specificity of MODS test in comparison to the Lowenstein-Jensen medium to diagnose tuberculosis among HIV seropositive individuals in GSL Medical College. METHODS: Sputum specimens were evaluated using smear microscopy, culture on Lowenstein-Jensen medium and MODS assay. A study subject is considered to have tuberculosis if at least 1 culture on Lowenstein-Jensen medium or MODS technique showed growth for M. tuberculosis. RESULTS: Spot Morning sputum samples were obtained from 873 HIV seropositive individuals. Two hundred and ninety seven (34%) [95% CI=30.8-37.2] patients were culture positive by MODS and 277 (32%) [95% CI=28.7-34.9] were culture positive on LJ slopes (P < 0.001). MODS sensitivity was 99.3% and specificity was 96.3%. Mean times for TB detection were 21 days (range 15-25 days) and 12 days (range 7-15 days) for culture on Lowenstein-Jensen medium and MODS (including drug susceptible testing) respectively (P<0.001). Culture contamination was low in MODS assay than culture on Lowenstein-Jensen medium (1.35 vs. 15.6%; P<0.001). Drug resistance was 12.6% for both RIF and INH, 12.6 % for RIF and 15% for INH. CONCLUSIONS: The MODS assay is a relatively simple test whose good performance for detection of pulmonary tuberculosis in HIV patients may make it suitable for resource-limited environments.

Prevalence of pre-XDR-TB, XDR-TB among MDR-TB Patients registered at Ojha Institute of Chest Diseases, Karachi

European Respiratory Journal, 2015

Re-recurrent Dermatofibrosarcomaprotuberans of the chest wall

JPMA. The Journal of the Pakistan Medical Association, 2015

Dermatofibrosarcomaprotuberans is a rare, soft tissue tumour with high rate of recurrence. It is ... more Dermatofibrosarcomaprotuberans is a rare, soft tissue tumour with high rate of recurrence. It is locally aggressive, with a low rate of metastasis. We describe the case of a 42 year old man who presented with a re-recurrent, large tumour situated on the anterior chest wall in the sternal region. We did a wide local excision and covered the resulting defect by using bilateral, pectoralis major myocutaneous flaps. Histopathology and immunohistochemical staining findings were consistent with the diagnosis of Dermatofibrosarcoma Protuberance. Post operatively the patient was treated with chemotherapy and radiotherapy.