Nongyao Kasatpibal - Academia.edu (original) (raw)

Papers by Nongyao Kasatpibal

Antimicrobial Stewardship & Healthcare Epidemiology, Dec 31, 2022

Objectives: This study aimed to determine the impacts of the COVID-19 pandemic and policy measure... more Objectives: This study aimed to determine the impacts of the COVID-19 pandemic and policy measures and delineate the impact of each on a cohort of Thai citizens. Methods: A cross-sectional study was conducted among 2,500 Thai people from October 2020 to January 2021. A questionnaire collecting demographic information and other data was sent to eligible subjects. Results: Overall, 51.6% and 49.5% of participants felt the impacts of COVID-19 and policy measures at the highest level, respectively. The study demonstrated that the weighted effect of the impact of the COVID-19 outbreak was statistically (p < .001) greater than that of policy measures on family (0.664 vs 0.618), education (0.562 vs 0.557), and the economy (0.643 vs 0.572). The weighted effect of the impact of policy measures was statistically (p < .001) greater than that of the COVID-19 pandemic on people's daily activities (0.675 vs 0.651), cultural/traditional or community way of life (0.769 vs 0.736), access to healthcare services and infection prevention supplies (0.410 vs 0.390), and mental health (0.625 vs 0.584). Conclusions: About half of the participants had a high level of impact from both the COVID-19 pandemic and policy measures. The results of this study suggest that policy measures need to be judged with caution, and the government should provide more comprehensive support to reduce the impact on people's lives.

Pacific Rim International Journal of Nursing Research

Multidrug-resistant organism infections are a major public health problem. Promoting nur... more Multidrug-resistant organism infections are a major public health problem. Promoting nurses’ practice in preventing multidrug-resistant infections can reduce hospital transmission. This quasi-experimental study investigated the effectiveness of a preventive nursing program for multidrug-resistant organism transmission. The study was carried out in the Department of Internal Medicine in a tertiary hospital in south Thailand. Participants in this study were registered nurses. Two wards were randomly selected as the experimental ward and two as the control ward, then participants from each ward were purposively selected. Finally, there were 60 participants, n = 31 from the experiment wards and n = 29 from the control wards. The experimental group received a 4-week program, whereas the control group followed the usual practice. Then, the practices in preventing multidrug-resistant organism transmission of the experimental and control groups were assessed 4 and 12 weeks after th...

American Journal of Infection Control, Jun 1, 2023

American Journal of Infection Control, 2016

Background: Operating room nurses are at high risk for occupational exposure to bloodborne pathog... more Background: Operating room nurses are at high risk for occupational exposure to bloodborne pathogens. This study examined the prevalence of and risk factors for needlestick injuries (NSIs), sharps injuries (SIs), and blood and body fluid exposures (BBFEs) among operating room nurses in Thai hospitals. Methods: A cross-sectional study was performed in 247 Thai hospitals. Questionnaires eliciting demographic data and information on injury occurrence and risk factors were distributed to 2500 operating room nurses, and 2031 usable questionnaires were returned, for a response rate of 81.2%. Adjusted odds ratios (ORs) and 95% confidence intervals (CIs) were calculated using multiple logistic regression analysis.

Journal of General Internal Medicine, Jun 24, 2008

BACKGROUND: There are limited data describing how pre-existing heart failure affects mortality fo... more BACKGROUND: There are limited data describing how pre-existing heart failure affects mortality following pneumonia. OBJECTIVE: To examine the association between history and severity of heart failure and mortality among patients hospitalized for pneumonia. DESIGN: Population-based cohort study in Western Denmark between 1994 and 2003. PATIENTS: 33,736 adults with a first-time hospitalization for pneumonia. Heart failure was identified and categorized based on data linked from populationbased health care databases. MEASUREMENTS: We compared 30-day mortality between patients with pre-existing heart failure and other pneumonia patients, while adjusting for age, gender, comorbidity, and medication use. RESULTS: The 30-day mortality was 24.4% among heart-failure patients and 14.4% among other patients, with an adjusted 30-day mortality rate ratio (MRR) of 1.40 (95% CI: 1.29-1.51). Adjusted MRRs increased according to severity of pre-existing heart failure, as indicated by medication regimen: thiazide-based, MRR= 1.09 (95% CI: 0.79-1.50); loop-diuretics, MRR=1.25 (95% CI: 1.10-1.43); loop-diuretics and digoxin, MRR= 1.35 (95% CI: 1.18-1.55); loop-diuretics and spironolactone, MRR=1.72 (95% CI: 1.49-2.00). Pre-existing heart valve disease and atrial fibrillation substantially increased mortality. CONCLUSION: History and severity of heart failure are associated with a poor outcome for patients hospitalized with pneumonia.

Journal of Nursing Education and Practice, May 16, 2016

Background: A clinical skills laboratory enhances the learning of nursing skills that can be tran... more Background: A clinical skills laboratory enhances the learning of nursing skills that can be translated to real professional practice. However, effective laboratory learning material that facilitates learners to achieve learning objectives may be inadequate in resource-limited settings. This study aimed to develop models for practicing wound dressing changes and to evaluate the quality of the model and user satisfaction. Methods: The study was conducted in three phases: 1) preparing for model development, 2) model development, and 3) evaluation of the quality of the model and user satisfaction. Convenience sampling was used to recruit both nursing instructors and nursing students, 30, 10 and 271 participants in the first, second, and third phases, respectively. Focus group discussions were held to gain ideas and opinions for developing the models. A Likert scale questionnaire was used to evaluate the quality of the model and user satisfaction. Results: The developed wound models were made from silicone. The quality evaluation form determined that the developed models had higher overall quality than those previous models available in the nursing laboratory center. User satisfaction with the developed models was high. The overall mean (SD) of user satisfaction toward the developed closed-wound model and open-wound model were 3.41 (0.72) and 3.44 (0.71), respectively. Conclusions: The developed wound models are potentially useful and user friendly, and could be easily available in settings of education with limited resources. Encouraging the students to use these models may help to enhance self-directed learning and clinical skills for application of wound dressings.

Pacific Rim international journal of nursing research, Jul 9, 2014

Globally and in Thailand there are growing numbers of youth living with HIV/ AIDS and they face c... more Globally and in Thailand there are growing numbers of youth living with HIV/ AIDS and they face challenges to HIV treatment adherence that can lead to treatment failure and drug resistance. This qualitative study explored the needs and concerns about adherence to HIV treatment among youth living with HIV/AIDS using a technical collaborative action research approach. Participatory activities and in-depth interviews were conducted among 25 youth living with HIV/AIDS in northern Thailand. Data were analyzed by content analysis. Findings show that participants did not adhere to HIV treatment and engaged HIV risk behaviors. There were five themes related to experiences regarding HIV treatment adherence, namely: lack of drug knowledge; boredom, discouragement, and denial; fear of disclosure; not managing medication, and risk-taking. We concluded that the participants needed psycho-social support and counseling to enhance HIV treatment. Nurses can play a critical role in developing and implementing effective programs and strategies that involve youth living with HIV/AIDS, giving them support and helping them, their families, and other health care providers to achieve HIV treatment success.

Journal of Patient Safety, Dec 12, 2017

Objectives: A surgical safety checklist has been a globally implemented and mandated adoption in ... more Objectives: A surgical safety checklist has been a globally implemented and mandated adoption in several countries. However, its use is not mandatory in Thailand. This study aimed to evaluate the perceptions of surgical personnel on surgical complications and safety and to examine the satisfaction and barriers of surgical safety checklist implementation. Methods: A survey study was performed between November 2013 and February 2015 in 61 Thai hospitals. A questionnaire capturing demographics, perceptions related to surgical complications and safety, and the satisfaction and barriers of surgical safety checklist implementation was distributed to surgical personnel. Results: A total of 2024 surgical personnel were recruited. Nearly all of them reported experience or knowledge of an adverse surgical event (99.6%). Most thought that it could be preventable (98.2%) and quality care improvement could help reduce the occurrence of adverse events (97.7%). Overall, respondents reported a high level of satisfaction with the checklist (mean[SD] = 3.79[0.71]). The three areas of highest satisfaction were benefit to the patient (mean [SD] = 4.11[0.69]), benefit to the organization (mean [SD] = 4.05[0.68]), and reduction in adverse events (mean [SD] = 4.02[0.69]). Overall, the barrier for implementation of the checklist was rated as moderate (mean[SD] = 2.52[0.99]). However, the means of barriers in each period, sign in, time out, and sign out, were rated as low (means [SD] = 2.41[1.07], 2.50[1.03], and 2.34[1.01], respectively). Conclusions: The data document that the satisfaction with the checklist are fairly high. However, some barriers were identified. Efforts to increase understanding through more rigorous policy enforcement and strategic support may lead to improving the checklist implementation.

Nursing open, Mar 24, 2021

The emergence of multidrug-resistant organisms (MDROs) is the greatest current threat to public h... more The emergence of multidrug-resistant organisms (MDROs) is the greatest current threat to public health worldwide (World Health Organization [WHO], 2014). Recently, carbapenem-resistant Enterobacteriaceae (CRE), Acinetobacter baumannii (CRAB), Pseudomonas aeruginosa (CRPsA) and vancomycin-resistant Enterococcus (VRE) are an emerging or serious cause of healthcareassociated infection (HAI), particularly among critically ill patients admitted to intensive care units (ICUs) (Gomez-Simmonds et al., 2016;

Antimicrobial Resistance and Infection Control, Jan 22, 2018

Background: Cesarean surgical site infections (SSIs) can be prevented by proper preoperative anti... more Background: Cesarean surgical site infections (SSIs) can be prevented by proper preoperative antibiotic prophylaxis. Differences in antibiotic selection in clinical practice exist according to obstetricians' preferences despite clear guidelines on preoperative antibiotic prophylaxis. This study aimed to compare the efficacy of ampicillin and ceftriaxone in preventing cesarean SSIs. Methods: The observational prospective cohort study was conducted at a tertiary hospital in Thailand from 1 January 2007 to 31 December 2012. Propensity scores for ceftriaxone prophylaxis were calculated from potential influencing confounders. The cesarean SSI rates of the ceftriaxone group vs. those of the ampicillin prophylactic group were estimated by multilevel mixed-effects Poisson regression nested by propensity score. Results: Data of 4149 cesarean patients were collected. Among these, 911 patients received ceftriaxone whereas 3238 patients received ampicillin as preoperative antibiotic prophylaxis. The incidence of incisional SSIs was (0.1% vs. 1.2%; p = 0.001) and organ space SSIs was (1.2% vs. 2.9%; p = 0.003) in the ceftriaxone group compared with the ampicillin group. After adjusting for confounders, the rate ratios of incisional and organ/space SSIs in the ceftriaxone compared with the ampicillin group did not differ (RR, 0.23; 95% CI 0.03-1.78), and (RR, 1.62; 95% CI 0.83-3.18), respectively. Conclusion: These data indicate no difference exists between ampicillin and ceftriaxone to prevent SSIs after cesarean section. Ampicillin may be used as antibiotic prophylaxis in cesarean section.

Clinical Epidemiology, May 1, 2009

Surveillance of surgical site infections (SSI) provides data upon which interventions to improve ... more Surveillance of surgical site infections (SSI) provides data upon which interventions to improve patient safety can be based. In Thailand, however, SSI surveillance has not yet been standardized. Objectives: To develop a standardized SSI surveillance system and to monitor SSI rates after introduction of such a system. Methods: We conducted a prospective study among 17,752 patients who underwent surgery in ten hospitals in Thailand from April 2004 to May 2005. The SSI rates were computed and benchmarked with the US rates, reported in terms of standardized infection ratio (SIR). We estimated the incidence rate ratio of surgical site infections by comparing the incidence in the last study period with the incidence in the first study period. Results: The study included 17,869 operations and identified 248 SSIs, yielding an SSI rate of 1.4 infections/100 operations and a corresponding SIR of 0.6 (95% confidence interval [CI] = 0.5-0.7). During the study period the overall SSI rate decreased from 1.8 infections/100 operations to 1.2 infections/100 operations, yielding an incidence rate ratio of 0.65 (95% CI = 0.47-0.89). Conclusion: Our study highlighted that a standardized SSI surveillance in a developing country can be initiated through a network and may be followed by a decrease in SSI rates.

OncoTargets and Therapy, Jul 1, 2014

The study aimed to determine the prognostic impact of clinical and pathological factors on surviv... more The study aimed to determine the prognostic impact of clinical and pathological factors on survival among patients with small cell neuroendocrine carcinoma (SNEC), adenocarcinoma (ADC), and squamous cell carcinoma (SCC). Methods: Eligible participants were all patients with histologically confirmed cervical cancer treated at Chiang Mai University Hospital between 1995 and 2011. We included all patients with SNEC and randomly enrolled patients with ADC and SCC. We used competing-risk regression analysis to examine the risk of cancer-related death by histological type. Results: We included 130 (6.2%) women with SNEC, 346 (16.4%) with ADC, and 1,632 (77.4%) with SCC. Age .60 years (hazard ratio [HR] 4.9, 95% confidence interval [CI] 2.0-12.0) and lymph node involvement (HR 3.0, 95% CI 1.2-7.4) were prognostic factors among surgicallytreated patients with SNEC. Deeper stromal invasion (HR 3.6, 95% CI 1.6-8.3) was a prognostic factor in patients with SCC. In patients with advanced SNEC, age .60 years had a strong prognostic impact (HR 2.6, 95% CI 1.0-6.5) while the International Federation of Gynecology and Obstetrics stages III and IV were prognostic factors for patients with advanced stage ADC (HR 2.9, 95% CI 2.0-4.4 and HR 4.5, 95% CI 2.6-7.9, respectively) and SCC (HR 1.7, 95% CI 1.4-2.0 and HR 3.7, 95% CI 2.8-4.9, respectively) compared with the International Federation of Gynecology and Obstetrics stage IIB. Conclusion: Clinical and pathological prognostic factors in cervical cancer differed according to histological type. Taking the important prognostic factors for each histological type into consideration may be beneficial for tailored treatment and follow-up planning.

Clinical and Experimental Gastroenterology, Dec 1, 2011

Limited data currently exists regarding the diagnostic indicators of peptic ulcer perforation for... more Limited data currently exists regarding the diagnostic indicators of peptic ulcer perforation for early detection among patients in Thailand. Delayed diagnosis and treatment for an ulcer can be life-threatening, resulting in shock or death. Objective: To determine the diagnostic indicators of peptic ulcer perforation. Material and methods: A cohort study was conducted in a tertiary care hospital in Thailand from 2005 to 2009. Peptic ulcer patients aged 15 years and over admitted to the surgical department were included. The diagnostic indicators used criteria of the patients' final diagnoses and operations, coded according to the International Statistical Classification of Diseases and Related Health Problems, 10th Revision, which included patient profiles, gender, age, coexisting illnesses, personal habits, signs and symptoms, laboratory investigations, radiological finding, and treatment role. Exponential risk regression analyses to obtain relative risk (RR) estimates for diagnostic indicators were analyzed using Stata ® statistical software package, version 11 (StataCorp LP, College Station, TX). Results: The study included 1290 patients. Of these, 57% reported perforated peptic ulcer. Multivariate analysis showed five diagnostic indicators: signs and symptoms including intense abdominal pain (RR = 1.53, 95% confidence interval [CI] 1.14-2.06), tenderness (RR = 1.94, 95% CI 1.17-3.21), and guarding (RR = 1.52, 95% CI 1.05-2.20); X-ray with free air (RR = 2.80, 95% CI 2.08-3.77); and referral from other hospitals (RR = 1.37, 95% CI 1.03-1.82). Conclusion: Five diagnostic indicators for peptic ulcer perforation monitoring were suggested from this study. Improving diagnostic indicators for medical care may improve the outcome of patients that have perforated peptic ulcer.

American Journal of Infection Control, Dec 1, 2005

Background: No previous multicenter data regarding the incidence of surgical site infection (SSI)... more Background: No previous multicenter data regarding the incidence of surgical site infection (SSI) are available in Thailand. The magnitude of the problem resulting from SSI at the national level could not be assessed. The purpose of this study was to estimate the incidence of SSI in 9 hospitals, together with patterns of surgical antibiotic prophylaxis, risk factors for SSI, and common causative pathogens. Methods: A prospective data collection among patients undergoing surgery in 9 hospitals in Thailand was conducted. The National Nosocomial Infection Surveillance (NNIS) system criteria and method were used for identifying and diagnosing SSI. The SSI rates were benchmarked with the NNIS report by means of indirect standardization and reported in terms of standardized infection ratio (SIR). Antibiotic prophylaxis was categorized into preoperative, intraoperative, and postoperative. Risk factors for SSI were evaluated using multiple logistic regression models. Results: From July 1, 2003, to February 29, 2004, the study included 8764 patients with 8854 major operations and identified 127 SSIs, yielding an SSI rate of 1.4 infections/100 operations and a corresponding SIR of 0.6 (95% CI: 0.5-0.8). Of these, 35 SSIs (27.6%) were detected postdischarge. The 3 most common operative procedures were cesarean section, appendectomy, and hysterectomy. The 3 most common pathogens isolated were Escherichia coli, Staphylococcus aureus, and Pseudomonas aeruginosa, which accounted for 15.3%, 8.5%, and 6.8% of infections, respectively. The 3 most common antibiotics used for prophylaxis were ampicillin/amoxicillin, cefazolin, and gentamicin. The proportion of types of antibiotic prophylaxis administered were 51.6% preoperative, 24.3% intraoperative, and 24.1% postoperative. Factors significantly associated with SSI were high degree of wound contamination, prolonged preoperative hospital stay, emergency operation, and prolonged duration of operation. Conclusion: Overall SSI rates were less than the average NNIS rates. The causative pathogens of SSI were different from those of other reports. There was a crucial proportion of operations that did not comply with the antibiotic guidelines. The risk factors for SSI identified in this study were consistent with most other reports.

Occupational medicine & health affairs, Jun 16, 2016

16th European Congress of Clinical Microbiology and Infectious Diseases (ECCMID), 2006

Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 2016

Background Ventilator-associated pneumonia (VAP) is the most common intensive care unit-acquired ... more Background Ventilator-associated pneumonia (VAP) is the most common intensive care unit-acquired infection, resulting in increased morbidity and mortality as well as increased hospital costs. Objective To determine the VAP rate before and after using the care bundle. Material and Method A pre- and intervention study was conducted in the Neurosurgical Critical Care Unit (NCCU) at a university hospital between April 2012 and February 2013. This was compared with the twelve-month period before intervention. The six-element VAP prevention bundle called Suandok Model was implemented. It included 30-degree head elevation, bedside hand hygiene, oral chlorhexidine mouth care, inflating of the cuff of the endotracheal tube maintaining 20 to 25 mmHg, checking residual gastric content before feeding, and implementing a weaning protocol. Results The samples before and after interventions were 66 and 68 cases, respectively. There were no significant differences between sex, age, GCS, diagnosis, ...

American Journal of Infection Control

Background: A 2014 study assessed infection prevention (IP) practices in Thai hospitals for cathe... more Background: A 2014 study assessed infection prevention (IP) practices in Thai hospitals for catheter-associated urinary tract infection (CAUTI), central line-associated bloodstream infection (CLABSI), and ventilatorassociated pneumonia (VAP). This study compares current IP practices to results obtained in 2014. Methods: Between February 1, 2021 and August 31, 2021, we resurveyed Thai hospitals regarding practices to prevent CAUTI, CLABSI, and VAP. We also assessed COVID-19 impact and healthcare worker burnout and coping strategies. We distributed 100 surveys to a convenience sample of infection preventionists. Results: Response rate: 100%. One-third (31%) of hospitals reported excellent leadership support for infection control (ie, responses of "good" or "excellent" to one survey question). Some prevention practices increased between 2014 vs 2021 (CAUTI: catheter reminder/stop-order/nurse-initiated discontinuation [50.0% vs 70.0%, P < .001]; condom catheters [36.3% vs 51.0%, P = .01]; ultrasound bladder scanner [4.7% vs 12.0%, P = .03]; CLABSI: chlorhexidine gluconate insertion site antisepsis [73.6% vs 85.0%, P = .03]; maximum sterile barrier precautions [63.2% vs 80.0%, P = .003]; VAP: selective digestive tract decontamination [26.9% vs 40.0%, P = .02]). Antimicrobial catheter use decreased since 2014 (10.4% vs 3.0%, P < .001). Many other practices remain suboptimal. COVID-19 challenges: staff shortages (71%), financial hardships (67%). Only 46% of infection preventionists felt safe working during COVID-19. Conclusions: More national strategic support is needed for IP programs to prevent CAUTI, CLABSI, VAP and healthcare worker well-being in Thailand during the COVID-19 pandemic.

Development of a simplified diagnostic indicators scoring system and validation for peptic ulcer ... more Development of a simplified diagnostic indicators scoring system and validation for peptic ulcer perforation in a developing country