Norman Stoller - Academia.edu (original) (raw)
Papers by Norman Stoller
PubMed, 1999
Tooth wear is an increasing problem in dentistry. Traditionally, it has been divided into three c... more Tooth wear is an increasing problem in dentistry. Traditionally, it has been divided into three categories: abrasion, attrition, and erosion. However, most clinical cases of tooth wear involve more than one of these processes. It is often easier to make a diagnosis by looking for the signs of the fundamental wear processes rather than trying to categorize the individual case. Wear can be caused by direct surface-to-surface wear, an intervening slurry, or a corrosive environment. Wear occurs during mastication, but also at other times, often at night. Although it may be possible to institute a preventive regimen, this will not always help the patient if his or her prime concern is esthetics. The same processes that cause tooth wear will cause wear to restorative materials. To diagnose and prevent wear, its processes must be understood.
Infection and Immunity, Jun 1, 1977
Journal of the Colorado Dental Association, 1989
Anesthesia progress
administration of pancuronium bromide into the abdomen and the use of a special respirator for sm... more administration of pancuronium bromide into the abdomen and the use of a special respirator for small animals.
Journal of Periodontology, 1997
This multi-center single-blind study compared clinical outcomes following guided tissue regenerat... more This multi-center single-blind study compared clinical outcomes following guided tissue regeneration (GTR) treating human Class II furcation defects with a new polylactic-acid-based bioabsorbable barrier (test treatment) or a non-absorbable ePTFE barrier (control treatment). Clinical parameters evaluated were change in vertical attachment level (VAL), horizontal attachment level (HAL), probing depth (PD), and gingival margin location (REC). Surgical treatment resulted in clinically and statistically equivalent changes when comparisons were made between test and control treatments. VAL gain was 2.0 mm for test and 1.6 mm for control groups; HAL gain was 2.1 mm for both test and control groups. PD reduction was 2.3 mm for the test group and 2.1 mm for the control group. Test sites experienced an additional 0.3 mm of recession beyond baseline; control sites, 0.5 mm. Within-group comparisons showed that the amount of recession was not significantly different from baseline in the test group. Recession in the control group was significantly different from baseline. All other parameters in both the test and control groups were significantly different from baseline. Evaluation of safety data indicated no significant differences between test and control treatments, although there was a strong trend for the control group to have more postoperative abscess or suppuration than test sites (control = 11; test = 4; P = 0.06).
Journal of periodontology, 1981
Eighteen patients with mobile mandibular anterior teeth were randomly assigned to one of two trea... more Eighteen patients with mobile mandibular anterior teeth were randomly assigned to one of two treatment groups in order to determine the relative effectiveness of two modalities of temporary stabilization. The two groups were well matched for initial horizontal tooth mobility, age and sex. Patients in Group I had their stabilized in the conventional fashion with extracoronal wire ligation. The Group II subjects' mandibular anterior teeth were acid-etched and then had composite restorative material applied to the lingual, facial and interproximal surfaces. Horizontal tooth mobility utilizing the periodontometer was recorded prior to, immediately after, and then at 1, 3, 6 and 12 months poststabilization. Löe's Gingival Index and the Silness and Löe Plaque Index were recorded for the same time periods. All subjects were instructed in oral hygiene techniques appropriate for splinted teeth. The mobility scores for both Group I and II dropped to significantly lower levels immediat...
Clinical preventive dentistry
Pharmacology and therapeutics in dentistry, 1980
Twenty-four normal healthy patients were scored for plaque by four examiners with different profe... more Twenty-four normal healthy patients were scored for plaque by four examiners with different professional backgrounds and different levels of training. Each patient was examined twice by each examiner according to a predetermined random assignment with the assumption of no change in state. All four examiners scored higher on the second examination and there was no apparent consistent relationship between professional background and level of training in the plaque scoring.
Oral surgery, oral medicine, and oral pathology, 1987
The purpose of this study was to evaluate the effectiveness of high frequency neural modulation a... more The purpose of this study was to evaluate the effectiveness of high frequency neural modulation as a substitute for traditional local anesthesia in various dental procedures. This double-blinded study was done to evaluate patient comfort and degree of satisfaction as well as manageability of pain control by the operator during the dental procedures. Procedures included restorations, tooth extractions, root planing, pulp extirpation, and temporomandibular joint therapy. In the experimental group, favorable responses ranged from 0.0% to 92.8%, depending on the procedures. An overall favorable rating of 71.8% was given by the experimental group, and an overall favorable response of 8.5% was given by the placebo group.
Journal of the American Veterinary Medical Association, 1986
Periodontal examinations were performed on ten 1- to 22-year-old snow leopards (6 males and 4 fem... more Periodontal examinations were performed on ten 1- to 22-year-old snow leopards (6 males and 4 females), using dentistry methods for determining the plaque and gingival indices. All tooth surfaces were probed, and alveolar bone attachment loss was determined. After subgingival plaque removal, plaque specimens were examined for differential bacterial morphotypes. The small number of leopards evaluated precluded definitive statistical analysis. However, the progression from gingival health to gingivitis to periodontitis was similar to that seen in man. Therefore, the use of plaque index, gingival index, alveolar bone attachment loss, and differential bacterial morphotypes can be used to determine the dental health of snow leopards.
Journal of the American Dental Association (1939), 1989
Journal of periodontology, 1990
Compendium (Newtown, Pa.), 1992
Pharmacology and therapeutics in dentistry, 1979
Tiodonium chloride was evaluated for its efficacy against Streptococcus mutans. Depending upon th... more Tiodonium chloride was evaluated for its efficacy against Streptococcus mutans. Depending upon the concentration used, it was found to have either bacteriocidal or bacteriostatic activity against S mutans and ti inhibit the accumulation of plaque formed in vitro by this organism. When applied as a mouthrinse in hamsters infected with S mutans, tiodonium chloride significantly reduced the accumulation of dental plaque. Chlorhexidine gluconate was tested as a positive control in the in vivo experiment.
Oral Surgery, Oral Medicine, Oral Pathology, 1992
A set of data to compare the absorbed dose delivered by tomographic implant site assessment techn... more A set of data to compare the absorbed dose delivered by tomographic implant site assessment techniques was generated. Absorbed doses were measured in fourteen anatomic sites from (I) computed tomography scans and (2) a series of tomographic cuts performed on a linear tomography unit. The doses to the thyroid gland, the active bone marrow, the brain, the salivary glands, and the eyes were determined with the use of a tissue-equivalent phantom with lithium fluoride thermoluminescent dosimeters at the appropriate locations.
Journal of Periodontology, 1990
The measurement of gingival crevicular fluid (GCF) is commonly used in clinical studies to quanti... more The measurement of gingival crevicular fluid (GCF) is commonly used in clinical studies to quantitate the severity of gingival inflammation. This study examined the influence of the presence of supragingival plaque on GCF readings. Bilateral pairs of maxillary premolars received replicate GCF measurements. One of the teeth was randomly selected to be the test tooth. Supragingival plaque was removed from the test tooth between the first and second GCF measurements. Plaque was not removed from the control tooth. The crevicular fluid was collected on filter paper strips which were placed just subgingivally. The quantity of crevicular fluid was determined with the aid of the Periotron 6000. The mean difference between the first and second GCF measurement for the control teeth was -1.5 +/- 5.7 (+/- SD). This change was not significant (P = 0.21). The mean difference between the first and second GCF measurements for the experimental teeth (-21.3 +/- 16.5) was significant (P less than or equal to .001). The mean difference between the control and the experimental GCF differences were found to be highly significant (P less than or equal to .001). The data indicate that the presence of supragingival plaque can significantly elevate the GCF measurements when determined with the Periotron 6000.
Journal of Periodontology, 1999
Background: The clinical efficacy and safety of doxycycline hyclate (8.5% w/w) delivered subgingi... more Background: The clinical efficacy and safety of doxycycline hyclate (8.5% w/w) delivered subgingivally in a biodegradable polymer (DH) was compared to placebo control (VC), oral hygiene (OH), and scaling and root planing (SRP) in 2 multi-center studies. Methods: Each study entered 411 patients who demonstrated moderate to severe periodontitis. Patients had 2 or more quadrants each with a minimum of 4 qualifying pockets ≥5 mm that bled on probing. At least 2 of the pockets were ≥7 mm. Treatment with DH, VC, OH, or SRP was provided at baseline and again at month 4. Clinical parameters were recorded monthly. Results: DH and SRP resulted in nearly identical clinical changes over time in both studies. Mean 9 month clinical attachment level gain (ALG) was 0.8 mm for the DH group and 0.7 mm for the SRP group in Study 1, and 0.8 mm (DH) and 0.9 mm (SRP) in Study 2. Mean probing depth (PD) reduction was 1.1 mm for the DH group and 0.9 mm for the SRP group in Study 1 and 1.3 mm for both groups in Study 2. Frequency distributions showed an ALG ≥2 mm in 29% of DH sites versus 27% of SRP sites in Study 1 and 31% of DH sites versus 34% of SRP sites in Study 2. PD reductions ≥2 mm were seen in 32% of DH sites versus 31% of SRP sites in Study 1 and 41% of DH sites versus 43% of SRP sites in Study 2. Comparisons between DH, VC, and OH treatment groups showed DH treatment to be statistically superior to VC and OH. Safety data demonstrated a benign safety profile with use of the DH product. Conclusions: Results of this trial demonstrate that treatment of periodontitis with subgingivally delivered doxycycline in a biodegradable polymer is equally effective as scaling and root planing and superior in effect to placebo control and oral hygiene in reducing the clinical signs of adult periodontitis over a 9-month period. This represents positive changes resulting from the use of subgingivally applied doxycycline as scaling and root planing was not limited regarding time of the procedure or use of local anesthesia.
Journal of Periodontology, 2001
This case report describes human histologic data of periodontal regeneration following guided tis... more This case report describes human histologic data of periodontal regeneration following guided tissue regeneration therapy (GTR) with a bioabsorbable barrier composed of polylactic acid. The tooth that was examined was part of a previously published study of the clinical effects of GTR therapy without the use of bone or bone substitutes on Class II furcation defects. Twenty-five months following the surgical procedure, the tooth was extracted for non-periodontal reasons. During this extraction, the bone within the furcation that was treated in the study was luxated with the tooth. At the completion of the study (month 12), the furcation's vertical probing depth had decreased by 2 mm with a 2 mm gain in clinical attachment. The horizontal furcation measurement decreased by 3 mm. Following extraction, the tooth was prepared for light microscopy and sectioned in the mesial-distal plane. Reference notches were not placed in the tooth at the time of surgery as there were no plans to perform histologic analysis in the study. However, using the buccal root prominences and what we interpreted to be root planing marks on the cementum, we were able to demonstrate that complete periodontal regeneration occurred on the root surface that was exposed to the pocket environment prior to surgery. New alveolar bone, cementum, and periodontal ligament were consistently observed throughout the furcation in the areas that demonstrated clinical attachment gain and a decrease in horizontal probing depth. This case report adds to the accumulating evidence of histologic periodontal regeneration following guided tissue regeneration with bioabsorbable polylactic acid barriers.
PubMed, 1999
Tooth wear is an increasing problem in dentistry. Traditionally, it has been divided into three c... more Tooth wear is an increasing problem in dentistry. Traditionally, it has been divided into three categories: abrasion, attrition, and erosion. However, most clinical cases of tooth wear involve more than one of these processes. It is often easier to make a diagnosis by looking for the signs of the fundamental wear processes rather than trying to categorize the individual case. Wear can be caused by direct surface-to-surface wear, an intervening slurry, or a corrosive environment. Wear occurs during mastication, but also at other times, often at night. Although it may be possible to institute a preventive regimen, this will not always help the patient if his or her prime concern is esthetics. The same processes that cause tooth wear will cause wear to restorative materials. To diagnose and prevent wear, its processes must be understood.
Infection and Immunity, Jun 1, 1977
Journal of the Colorado Dental Association, 1989
Anesthesia progress
administration of pancuronium bromide into the abdomen and the use of a special respirator for sm... more administration of pancuronium bromide into the abdomen and the use of a special respirator for small animals.
Journal of Periodontology, 1997
This multi-center single-blind study compared clinical outcomes following guided tissue regenerat... more This multi-center single-blind study compared clinical outcomes following guided tissue regeneration (GTR) treating human Class II furcation defects with a new polylactic-acid-based bioabsorbable barrier (test treatment) or a non-absorbable ePTFE barrier (control treatment). Clinical parameters evaluated were change in vertical attachment level (VAL), horizontal attachment level (HAL), probing depth (PD), and gingival margin location (REC). Surgical treatment resulted in clinically and statistically equivalent changes when comparisons were made between test and control treatments. VAL gain was 2.0 mm for test and 1.6 mm for control groups; HAL gain was 2.1 mm for both test and control groups. PD reduction was 2.3 mm for the test group and 2.1 mm for the control group. Test sites experienced an additional 0.3 mm of recession beyond baseline; control sites, 0.5 mm. Within-group comparisons showed that the amount of recession was not significantly different from baseline in the test group. Recession in the control group was significantly different from baseline. All other parameters in both the test and control groups were significantly different from baseline. Evaluation of safety data indicated no significant differences between test and control treatments, although there was a strong trend for the control group to have more postoperative abscess or suppuration than test sites (control = 11; test = 4; P = 0.06).
Journal of periodontology, 1981
Eighteen patients with mobile mandibular anterior teeth were randomly assigned to one of two trea... more Eighteen patients with mobile mandibular anterior teeth were randomly assigned to one of two treatment groups in order to determine the relative effectiveness of two modalities of temporary stabilization. The two groups were well matched for initial horizontal tooth mobility, age and sex. Patients in Group I had their stabilized in the conventional fashion with extracoronal wire ligation. The Group II subjects' mandibular anterior teeth were acid-etched and then had composite restorative material applied to the lingual, facial and interproximal surfaces. Horizontal tooth mobility utilizing the periodontometer was recorded prior to, immediately after, and then at 1, 3, 6 and 12 months poststabilization. Löe's Gingival Index and the Silness and Löe Plaque Index were recorded for the same time periods. All subjects were instructed in oral hygiene techniques appropriate for splinted teeth. The mobility scores for both Group I and II dropped to significantly lower levels immediat...
Clinical preventive dentistry
Pharmacology and therapeutics in dentistry, 1980
Twenty-four normal healthy patients were scored for plaque by four examiners with different profe... more Twenty-four normal healthy patients were scored for plaque by four examiners with different professional backgrounds and different levels of training. Each patient was examined twice by each examiner according to a predetermined random assignment with the assumption of no change in state. All four examiners scored higher on the second examination and there was no apparent consistent relationship between professional background and level of training in the plaque scoring.
Oral surgery, oral medicine, and oral pathology, 1987
The purpose of this study was to evaluate the effectiveness of high frequency neural modulation a... more The purpose of this study was to evaluate the effectiveness of high frequency neural modulation as a substitute for traditional local anesthesia in various dental procedures. This double-blinded study was done to evaluate patient comfort and degree of satisfaction as well as manageability of pain control by the operator during the dental procedures. Procedures included restorations, tooth extractions, root planing, pulp extirpation, and temporomandibular joint therapy. In the experimental group, favorable responses ranged from 0.0% to 92.8%, depending on the procedures. An overall favorable rating of 71.8% was given by the experimental group, and an overall favorable response of 8.5% was given by the placebo group.
Journal of the American Veterinary Medical Association, 1986
Periodontal examinations were performed on ten 1- to 22-year-old snow leopards (6 males and 4 fem... more Periodontal examinations were performed on ten 1- to 22-year-old snow leopards (6 males and 4 females), using dentistry methods for determining the plaque and gingival indices. All tooth surfaces were probed, and alveolar bone attachment loss was determined. After subgingival plaque removal, plaque specimens were examined for differential bacterial morphotypes. The small number of leopards evaluated precluded definitive statistical analysis. However, the progression from gingival health to gingivitis to periodontitis was similar to that seen in man. Therefore, the use of plaque index, gingival index, alveolar bone attachment loss, and differential bacterial morphotypes can be used to determine the dental health of snow leopards.
Journal of the American Dental Association (1939), 1989
Journal of periodontology, 1990
Compendium (Newtown, Pa.), 1992
Pharmacology and therapeutics in dentistry, 1979
Tiodonium chloride was evaluated for its efficacy against Streptococcus mutans. Depending upon th... more Tiodonium chloride was evaluated for its efficacy against Streptococcus mutans. Depending upon the concentration used, it was found to have either bacteriocidal or bacteriostatic activity against S mutans and ti inhibit the accumulation of plaque formed in vitro by this organism. When applied as a mouthrinse in hamsters infected with S mutans, tiodonium chloride significantly reduced the accumulation of dental plaque. Chlorhexidine gluconate was tested as a positive control in the in vivo experiment.
Oral Surgery, Oral Medicine, Oral Pathology, 1992
A set of data to compare the absorbed dose delivered by tomographic implant site assessment techn... more A set of data to compare the absorbed dose delivered by tomographic implant site assessment techniques was generated. Absorbed doses were measured in fourteen anatomic sites from (I) computed tomography scans and (2) a series of tomographic cuts performed on a linear tomography unit. The doses to the thyroid gland, the active bone marrow, the brain, the salivary glands, and the eyes were determined with the use of a tissue-equivalent phantom with lithium fluoride thermoluminescent dosimeters at the appropriate locations.
Journal of Periodontology, 1990
The measurement of gingival crevicular fluid (GCF) is commonly used in clinical studies to quanti... more The measurement of gingival crevicular fluid (GCF) is commonly used in clinical studies to quantitate the severity of gingival inflammation. This study examined the influence of the presence of supragingival plaque on GCF readings. Bilateral pairs of maxillary premolars received replicate GCF measurements. One of the teeth was randomly selected to be the test tooth. Supragingival plaque was removed from the test tooth between the first and second GCF measurements. Plaque was not removed from the control tooth. The crevicular fluid was collected on filter paper strips which were placed just subgingivally. The quantity of crevicular fluid was determined with the aid of the Periotron 6000. The mean difference between the first and second GCF measurement for the control teeth was -1.5 +/- 5.7 (+/- SD). This change was not significant (P = 0.21). The mean difference between the first and second GCF measurements for the experimental teeth (-21.3 +/- 16.5) was significant (P less than or equal to .001). The mean difference between the control and the experimental GCF differences were found to be highly significant (P less than or equal to .001). The data indicate that the presence of supragingival plaque can significantly elevate the GCF measurements when determined with the Periotron 6000.
Journal of Periodontology, 1999
Background: The clinical efficacy and safety of doxycycline hyclate (8.5% w/w) delivered subgingi... more Background: The clinical efficacy and safety of doxycycline hyclate (8.5% w/w) delivered subgingivally in a biodegradable polymer (DH) was compared to placebo control (VC), oral hygiene (OH), and scaling and root planing (SRP) in 2 multi-center studies. Methods: Each study entered 411 patients who demonstrated moderate to severe periodontitis. Patients had 2 or more quadrants each with a minimum of 4 qualifying pockets ≥5 mm that bled on probing. At least 2 of the pockets were ≥7 mm. Treatment with DH, VC, OH, or SRP was provided at baseline and again at month 4. Clinical parameters were recorded monthly. Results: DH and SRP resulted in nearly identical clinical changes over time in both studies. Mean 9 month clinical attachment level gain (ALG) was 0.8 mm for the DH group and 0.7 mm for the SRP group in Study 1, and 0.8 mm (DH) and 0.9 mm (SRP) in Study 2. Mean probing depth (PD) reduction was 1.1 mm for the DH group and 0.9 mm for the SRP group in Study 1 and 1.3 mm for both groups in Study 2. Frequency distributions showed an ALG ≥2 mm in 29% of DH sites versus 27% of SRP sites in Study 1 and 31% of DH sites versus 34% of SRP sites in Study 2. PD reductions ≥2 mm were seen in 32% of DH sites versus 31% of SRP sites in Study 1 and 41% of DH sites versus 43% of SRP sites in Study 2. Comparisons between DH, VC, and OH treatment groups showed DH treatment to be statistically superior to VC and OH. Safety data demonstrated a benign safety profile with use of the DH product. Conclusions: Results of this trial demonstrate that treatment of periodontitis with subgingivally delivered doxycycline in a biodegradable polymer is equally effective as scaling and root planing and superior in effect to placebo control and oral hygiene in reducing the clinical signs of adult periodontitis over a 9-month period. This represents positive changes resulting from the use of subgingivally applied doxycycline as scaling and root planing was not limited regarding time of the procedure or use of local anesthesia.
Journal of Periodontology, 2001
This case report describes human histologic data of periodontal regeneration following guided tis... more This case report describes human histologic data of periodontal regeneration following guided tissue regeneration therapy (GTR) with a bioabsorbable barrier composed of polylactic acid. The tooth that was examined was part of a previously published study of the clinical effects of GTR therapy without the use of bone or bone substitutes on Class II furcation defects. Twenty-five months following the surgical procedure, the tooth was extracted for non-periodontal reasons. During this extraction, the bone within the furcation that was treated in the study was luxated with the tooth. At the completion of the study (month 12), the furcation's vertical probing depth had decreased by 2 mm with a 2 mm gain in clinical attachment. The horizontal furcation measurement decreased by 3 mm. Following extraction, the tooth was prepared for light microscopy and sectioned in the mesial-distal plane. Reference notches were not placed in the tooth at the time of surgery as there were no plans to perform histologic analysis in the study. However, using the buccal root prominences and what we interpreted to be root planing marks on the cementum, we were able to demonstrate that complete periodontal regeneration occurred on the root surface that was exposed to the pocket environment prior to surgery. New alveolar bone, cementum, and periodontal ligament were consistently observed throughout the furcation in the areas that demonstrated clinical attachment gain and a decrease in horizontal probing depth. This case report adds to the accumulating evidence of histologic periodontal regeneration following guided tissue regeneration with bioabsorbable polylactic acid barriers.