Cristina Novello - Academia.edu (original) (raw)

Cristina Novello

Uploads

Papers by Cristina Novello

Research paper thumbnail of Programevaluering in maatskaplike werk

Research paper thumbnail of Spatial distribution of Calomera littoralis nemoralis (Olivier, 1790) in a coastal habitat of Southern Italy and its importance for conservation (Coleoptera Carabidae Cicindelinae)

The spatial distribution of Calomera littoralis nemoralis (Olivier, 1790) (Coleoptera Carabidae C... more The spatial distribution of Calomera littoralis nemoralis (Olivier, 1790) (Coleoptera Carabidae Cicindelinae) was studied on the marine sandy beach area of 1 km, near the mouth of a stream in Catanzaro province (Southern Italy, Calabria). During the sampling period (July-August 2011-2012) we investigated the distribution of adults of C. littoralis nemoralis by visual census method and the spatial distribution of larval burrows of C. littoralis nemoralis along three transects (A, B, parallel to the coast line; C, embracing the river mouth). All the transects were selected by soil microclimate (a higher or lower humidity) and food availability. Larval burrows distribution was performed using QGIS. The dispersal index (ID) shows regular distribution of adults along transects A and B while in C the individuals are aggregated. Concerning the larval galleries distribution, the QGIS analysis shows a significant difference in their spatial distribution. The sampled data were analyzed using univariate and multivariate statistical methods. This is the first report on spatial distribution of adults and larvae of C. littoralis nemoralis in relation to soil humidity and food availability. The adult home range of this species is much larger than the reproductive habitat, that seems limited to wet sandy river bank around the mouth. The importance of such experimental studies for cicindelid conservation is briefly discussed. Tiger beetles; Calomera littoralis; adults distribution; larval burrows.

Research paper thumbnail of The number of pregnancies is a risk factor for Alzheimer's disease

European Journal of Neurology, Dec 1, 2006

Research paper thumbnail of L’Aplotipo H1 Del Gene Della Proteina Tau (Mapt) È Associato Con Il Disturbo Cognitivo Lieve, Una Condizione Prodromica Alla Malattia DI Alzheimer

Research paper thumbnail of Elevation of β-Amyloid 1-42 Autoantibodies in the Blood of Amnestic Patients With Mild Cognitive Impairment

Archives of Neurology, 2010

Research paper thumbnail of Possible Influence of a Non-Synonymous Polymorphism Located in the NGF Precursor on Susceptibility to Late-Onset Alzheimer's Disease and Mild Cognitive Impairment

Journal of Alzheimers Disease, 2012

Research paper thumbnail of The H1 haplotype of the tau gene (MAPT) is associated with mild cognitive impairment

Journal of Alzheimer's disease : JAD, 2010

Mild cognitive impairment is often considered a transitional condition prodromal to Alzheimer&#39... more Mild cognitive impairment is often considered a transitional condition prodromal to Alzheimer's disease. The dissection of genetic risk factors predisposing to mild cognitive impairment is paramount to assess the individual predisposition and reliably evaluate the effectiveness of early therapeutic interventions. We designed a cross-sectional analysis to test whether the occurrence of mild cognitive impairment is influenced by variations of the tau protein gene. The genotypes of seven polymorphisms tagging the major tau haplotypes were assayed on 186 patients with amnestic mild cognitive impairment and 191 unrelated controls. Association study was conducted by logistic regression including APOE genotype and age as covariates. Case-control analysis showed that the common H1 haplotype is significantly overrepresented in patients (OR, 95% CI: 2.31, 1.52-3.51; p<0.001), whereas did not provide positive signals for any of the H1 sub-haplotypes that had been described as associated...

Research paper thumbnail of Amyloid-β42 plasma levels are elevated in amnestic mild cognitive impairment

Journal of Alzheimer's Disease, 2009

Amnestic mild cognitive impairment (aMCI) is considered a prodromal stage of Alzheimer's disease ... more Amnestic mild cognitive impairment (aMCI) is considered a prodromal stage of Alzheimer's disease (AD). We measured plasma levels of amyloid-β40 (Aβ40) and Aβ42 in 191 subjects with aMCI. Seventy-nine of them were clinically followed for two years. In the total cohort of aMCI cases, the average level of Aβ42, as well as the Aβ42/Aβ40 ratio, was significantly higher than those of the 102 cognitively normal age-matched subjects. The aMCI cases that converted to probable AD within 2 years had higher levels of Aβ42 and, to a lesser extent, Aβ40 than the stable cases. However the large variability of measured values indicates that plasma Aβ is not a suitable marker of incipient AD.

Research paper thumbnail of Programevaluering in maatskaplike werk

Research paper thumbnail of Spatial distribution of Calomera littoralis nemoralis (Olivier, 1790) in a coastal habitat of Southern Italy and its importance for conservation (Coleoptera Carabidae Cicindelinae)

The spatial distribution of Calomera littoralis nemoralis (Olivier, 1790) (Coleoptera Carabidae C... more The spatial distribution of Calomera littoralis nemoralis (Olivier, 1790) (Coleoptera Carabidae Cicindelinae) was studied on the marine sandy beach area of 1 km, near the mouth of a stream in Catanzaro province (Southern Italy, Calabria). During the sampling period (July-August 2011-2012) we investigated the distribution of adults of C. littoralis nemoralis by visual census method and the spatial distribution of larval burrows of C. littoralis nemoralis along three transects (A, B, parallel to the coast line; C, embracing the river mouth). All the transects were selected by soil microclimate (a higher or lower humidity) and food availability. Larval burrows distribution was performed using QGIS. The dispersal index (ID) shows regular distribution of adults along transects A and B while in C the individuals are aggregated. Concerning the larval galleries distribution, the QGIS analysis shows a significant difference in their spatial distribution. The sampled data were analyzed using univariate and multivariate statistical methods. This is the first report on spatial distribution of adults and larvae of C. littoralis nemoralis in relation to soil humidity and food availability. The adult home range of this species is much larger than the reproductive habitat, that seems limited to wet sandy river bank around the mouth. The importance of such experimental studies for cicindelid conservation is briefly discussed. Tiger beetles; Calomera littoralis; adults distribution; larval burrows.

Research paper thumbnail of The number of pregnancies is a risk factor for Alzheimer's disease

European Journal of Neurology, Dec 1, 2006

Research paper thumbnail of L’Aplotipo H1 Del Gene Della Proteina Tau (Mapt) È Associato Con Il Disturbo Cognitivo Lieve, Una Condizione Prodromica Alla Malattia DI Alzheimer

Research paper thumbnail of Elevation of β-Amyloid 1-42 Autoantibodies in the Blood of Amnestic Patients With Mild Cognitive Impairment

Archives of Neurology, 2010

Research paper thumbnail of Possible Influence of a Non-Synonymous Polymorphism Located in the NGF Precursor on Susceptibility to Late-Onset Alzheimer's Disease and Mild Cognitive Impairment

Journal of Alzheimers Disease, 2012

Research paper thumbnail of The H1 haplotype of the tau gene (MAPT) is associated with mild cognitive impairment

Journal of Alzheimer's disease : JAD, 2010

Mild cognitive impairment is often considered a transitional condition prodromal to Alzheimer&#39... more Mild cognitive impairment is often considered a transitional condition prodromal to Alzheimer's disease. The dissection of genetic risk factors predisposing to mild cognitive impairment is paramount to assess the individual predisposition and reliably evaluate the effectiveness of early therapeutic interventions. We designed a cross-sectional analysis to test whether the occurrence of mild cognitive impairment is influenced by variations of the tau protein gene. The genotypes of seven polymorphisms tagging the major tau haplotypes were assayed on 186 patients with amnestic mild cognitive impairment and 191 unrelated controls. Association study was conducted by logistic regression including APOE genotype and age as covariates. Case-control analysis showed that the common H1 haplotype is significantly overrepresented in patients (OR, 95% CI: 2.31, 1.52-3.51; p<0.001), whereas did not provide positive signals for any of the H1 sub-haplotypes that had been described as associated...

Research paper thumbnail of Amyloid-β42 plasma levels are elevated in amnestic mild cognitive impairment

Journal of Alzheimer's Disease, 2009

Amnestic mild cognitive impairment (aMCI) is considered a prodromal stage of Alzheimer's disease ... more Amnestic mild cognitive impairment (aMCI) is considered a prodromal stage of Alzheimer's disease (AD). We measured plasma levels of amyloid-β40 (Aβ40) and Aβ42 in 191 subjects with aMCI. Seventy-nine of them were clinically followed for two years. In the total cohort of aMCI cases, the average level of Aβ42, as well as the Aβ42/Aβ40 ratio, was significantly higher than those of the 102 cognitively normal age-matched subjects. The aMCI cases that converted to probable AD within 2 years had higher levels of Aβ42 and, to a lesser extent, Aβ40 than the stable cases. However the large variability of measured values indicates that plasma Aβ is not a suitable marker of incipient AD.

Log In