Nyilo Purnami - Academia.edu (original) (raw)
Papers by Nyilo Purnami
F1000Research
Background: The purpose of this study was to obtain data on the prevalence of specialist doctors ... more Background: The purpose of this study was to obtain data on the prevalence of specialist doctors and Otorhinolaryngology-Head and Neck Surgery (ORL-HNS) residents in Indonesia who suffered from Coronavirus disease 2019 (COVID-19) after receiving the second dose of COVID-19 vaccination using the Sinovac vaccine (CoronaVac) and the length of time infected with COVID-19 after the second Sinovac vaccination. Methods: We performed a descriptive observational study, using a cross-sectional design. Data collection took place between August 2021 and October 2021. The respondents in this study included specialist doctors and ORL-HNS residents who worked in various hospitals in Indonesia who had received the second dose of the Sinovac vaccination. Data collection was performed by means of Self-reporting Online Survey Platform (Google Form). Results: This study included 1,530 respondents, and 54.2% of respondents were women. Respondents consisted of 68.6% ORL-HNS doctors and the rest were resi...
International Journal of Pediatric Otorhinolaryngology
eJournal Kedokteran Indonesia
This study’s objectives were to investigate factors affecting the adverse events of the COVID-19 ... more This study’s objectives were to investigate factors affecting the adverse events of the COVID-19 vaccine in Indonesia among health care workers and compare adverse events following SARS-CoV-2 vaccine using CoronaVac as the first and second dose and Moderna used as the booster third dose. A cross-sectional study was conducted using the Self-reporting Online Survey Platform (Google Form) from August to October 2021. Subjects included in the study were ENT specialists and residents all over Indonesia who had been vaccinated with both doses of CoronaVac COVID-19 vaccine and Moderna COVID-19 vaccine as a booster dose. Among a total of 1394 participants, 51.2% and 43.7% of subjects experienced adverse events following the first and second dose of the CoronaVac vaccine. Adverse events are significantly higher following the third dose of Moderna vaccine (95.3%) with p-value <0.001, odds ratio (OR) 26.63 (95% CI 19.87-35.7). Adverse events following the CoronaVac vaccine were significantl...
Proceedings of Meetings on Acoustics, 2019
Pure-tone audiometry as a gold standard is difficult to do in several places in Indonesia due to ... more Pure-tone audiometry as a gold standard is difficult to do in several places in Indonesia due to problems related to access, referral systems, and costs. Therefore, the examiner relies on the whisper test as a screening test. In this study, we evaluated the method of the whisper test by modifying the distance in order to make the procedure practical, simple and easy to perform in a smaller room with large groups. A crosssectional study between the modified whisper test and the reference test (pure-tone audiometry) was conducted on 618 selected participants. Based on diagnostic and screening test evaluation, it was known that sensitivity and specificity of the modified-distance whispered voice test were 13.43% and 99.27%, respectively. While the test yielded high PPV (69.23%) and NPV (90.41%) for a screening test. The likelihood ratio results were 18.50 for positive and 0.87 for negative. The other parameter results were 21.22 (DOR), 89.97% (diagnostic effectiveness), 10.03% (misclassification rate), and 0.13 (Youden's Index). This hearing screening method will help identify more hearing impairments for a considerable population, helping in referral planning.
Indian Journal of Forensic Medicine & Toxicology, 2021
Objective: socializing hearing loss examination and early detection to patients and their familie... more Objective: socializing hearing loss examination and early detection to patients and their families in deaf type B schools. Methods: A community service program in the form of socialization was performed to the family of patients with hearing loss in deaf school type B, Surabaya, Indonesia. Pretest and posttest were conducted to determine the initial understanding and post socialization knowledge of these people. We also asked the participants to fill on a questionnaire regarding the possible causes of the hearing loss (family history, drug use, history of disease, and history of head trauma). Results: Based on the summary of pretest and posttest from the participants, an increase in participants' knowledge of hearing lost was found. This activity was attended by 90 family members of 37 patients with hearing loss. Pre and post test results. The results of the questionnaire showed that 94.59% of the patients came from Javanese ethnicity. As many as 21.62% of patients had a family history of hearing loss, and even 2 patients had a father, mother, and sibling with hearing loss. A total of 18.92% had a history of using ototoxic drugs, 16.22% had a history of maternal Rubella infection during pregnancy, and 2.7% had a history of head trauma. Conclusion: Socialization program was effective to increase knowledge of congenital hearing loss for family of deaf schoolchildren. The result of the questionnaire showed that deaf schoolchildren had several risk factors for the occurrence of hearing loss. Similar program can be performed in communities in other areas to increase prevention and early detection of hearing loss in Indonesia.
Jurnal Layanan Masyarakat (Journal of Public Services), 2021
Hearing loss can disrupt communication, which has an impact on social, school, and work environme... more Hearing loss can disrupt communication, which has an impact on social, school, and work environments. Early detection and management of hearing loss can prevent it. The community is hoped to be contributed by raising awareness of hearing loss and its prevention. Therefore, educational activities in the form of counseling and training were carried out for various groups in Kalibaru Kulon village, Kalibaru Sub District, Banyuwangi District, East Java. The aim of the counseling and training on early detection of hearing loss for medical personnel is to increase their knowledge and skills at the Public Health Center (Puskesmas) to perform early detection and management of hearing loss. The purpose of hearing health counseling activities for “Satya Kencana” youth organizations is to increase their knowledge as a strategic age in the community to engage in early detection of hearing loss activities in the community. The training of medical personnel was conducted through lectures, practic...
Indian Journal of Forensic Medicine & Toxicology, 2021
Objective: Analyzing the association between pure tone audiometry and distortion of otoacoustic e... more Objective: Analyzing the association between pure tone audiometry and distortion of otoacoustic emission (DPOAE) in students after shooting practice.
Infectious Disease Reports, 2020
Background: Definition of Congenital Ruben Syndrome (CRS): a disease caused by rubella virus infe... more Background: Definition of Congenital Ruben Syndrome (CRS): a disease caused by rubella virus infection. Routine surveil- lance of CRS is part of a government pro- gram in documenting the incidence of CRS so that infants with CRS are diagnosed promptly and receive appropriate care. Objective: This study aims to repodiology Outpatient General Hospital Dr. Soetomo Surabaya.Method: A descriptive study from CRS surveillance data for the period from January 1st until December 31rd, 2015. Data was from Infants who came to the Audiology Outpatient General Hospital Dr. Soetomo Surabaya and did hearing and serological examination. Results: A total of 65 infants were involved in surveillance. The highest num- ber of patients was the age group 1- <3 years (21 patients, 31.2%). A total of 36 patients (55.4%) were male, 45 babies (69.2%) were suspected of suffering from CRS with 2 infants (3.1%) classified as a laboratory-confirmed CRS. Hearing abnor- malities were found in 36 infants (55.4%)....
Journal of Community Medicine and Public Health Research, 2020
Presbycusis is a disease that can befall the elderly, caused by a multifactorial process that sho... more Presbycusis is a disease that can befall the elderly, caused by a multifactorial process that should be allowed to disrupt communication and social life and cause mental disorders. According to WHO the proportion of the elderly population rises rapidly which is estimated in 2025, there are about 1,2 billion elderly people with a risk of presbycusis. Mr.S was 84 years old, married and had 2 children, complained of hearing loss since 10 years ago on the patient's left ear. The decline in hearing occurred gradually, giving the last 4 years after his wife's death. Patients was taken to Otorhinolaryngologist and expressed age-related hearing impairment and was advised to use hearing aids. Patients are not routinely using hearing aids. In addition, patients have hypertension and heart disease. Patients consumed Captopril 2x1 tablets, Fundifar 2x1, Furosemide 1x40 mg and Fargoxin 1x0.25 mg. Patients do not routinely consumed cardiac medicine and used hearing aids. From the results ...
Folia Medica Indonesiana, 2020
Long-term exposure to aminoglycoside such as kanamycin to cochlear cells is known to be associate... more Long-term exposure to aminoglycoside such as kanamycin to cochlear cells is known to be associated with damage to outer hair cells in the organ Corti and type 1 sensory hair cells in the vestibular organs which ultimately causes permanent damage to hair cells. Hair cell damage occurs from the basal cochlea (high frequency area) to the apex cochlea (low frequency area) and followed by damage from the auditory nerve. Evaluation of cochlear dysfunction on multidrug resistant tuberculosis (MDR TB) patients have been rarely reported in the literature based on distortion product otoacoustic emission (DPOAE). Objectives: To prove cochlear dysfunction after kanamycin injection in MDR TB patient based on DPOAE examination of the overall frequencies and specific frequency. This was an observational longitudinal analytic with pre and post design without control group conducted in the infection division of MDR TB Outpatients Pulmonology Department and Otorhinolaryngology Community division of O...
Journal of Community Medicine and Public Health Research, 2020
Congenital deafness is a hearing loss disorder that occurs at birth and is one of the disorders t... more Congenital deafness is a hearing loss disorder that occurs at birth and is one of the disorders that can cause complications when it is not treated.1 Children with hearing loss will face difficulties such as poor development outcomes, including poor speech and language skills and face difficulties with cognition and social-emotional interactions. Early intervention has been proven to be one of the most important factors leading to good outcomes for children with congenital hearing loss.2 This case study is intended to highlight the importance of early case detections, early interventions and how family support plays a crucial role in the development of children with hearing loss. With the support of her family, Ms. DRP has gone through several speech and hearing therapies since her surgery and has proven to have an above-average linguistic abilities, showing that early problem detection does not hinder the development and achievement of children with congenital hearing loss.
Journal of Community Medicine and Public Health Research, 2020
The high number of patients who come for ear therapy with massage skills, the P3T Center intends ... more The high number of patients who come for ear therapy with massage skills, the P3T Center intends to carry out an observational screening of ear therapy. This screening aims to find out how the diagnostic method and application of ear therapy with massage skills and the benefits of ear therapy to overcome the problem of hearing loss (hearing impairment). This screening design uses an observational method in which the researcher makes observations and interviews with respondents. Data collection techniques were carried out by looking at the results of the examination of respondents' hearing tests and the results of interviews with respondents. Patient therapy results in 18 people (60%) no progress or the same as the original condition. this shows that therapy can be said to be ineffective in curing ear disorders. The results of the audiometry examination of the right and left ear stated that none of the patients was normal. Even though there are patients who claim to be able to he...
Oto Rhino Laryngologica Indonesiana, Jun 27, 2019
Background: Presbycusis is a hearing loss due to the degeneration process in elderly people of 65... more Background: Presbycusis is a hearing loss due to the degeneration process in elderly people of 65 years old and beyond, characterized by a decrease in hearing sensitivity in both ears. Reactive oxygen species (ROS) are assumed to have an important role in the pathogenesis of presbycusis. Purpose: To find out the correlation between ROS levels in plasma and hearing threshold levels in presbycusis patients.
Oto Rhino Laryngologica Indonesiana, 2018
Background: Hearing loss is one of the congenital abnormalities frequently found in children, whi... more Background: Hearing loss is one of the congenital abnormalities frequently found in children, which is followed by delayed speech and language development. The majority of cases have unknown causes of hearing loss resulting in late diagnosis. Newborn Hearing Screening Program (NHSP) recommended Otoacoustic Emissions (OAE) and Brainstem Evoked Response Audiometry (BERA) as detection of hearing loss in infants and children. Objective: To obtain the prevalence and description of sensorineural hearing loss in infants and children. Method: A retrospective descriptive study of infants underwent OAE and BERA between 2011-2013 at Dr Soetomo Hospital. The degree of hearing loss was according to the International Standard Organization (ISO). Result: A total number of 552 infant and children were examined, and 377 (68%) were detected with sensorineural hearing loss (SNHL). This group of SNHL consisted of 199 males (52.79%) and 178 females (47.21%). The largest age group was 12 to 36 months, re...
Indonesian Journal of Tropical and Infectious Disease, 2020
Rubella infections in pregnant women, especially during the first trimester, often lead to manife... more Rubella infections in pregnant women, especially during the first trimester, often lead to manifest as congenital rubella syndrome (CRS). This syndrome consists of several inherited disorders such as deafness, cataracts, and cardiac abnormalities. Deafness is the most common manifestation of CRS, 70-90% of all cases with deafness type are sensory neural deafness. The mechanism of hearing loss due to rubella virus is caused by hypoxia resulting from endothelial vascular damage in cochlea, followed by cell death in the organ of Corti and stria vascularis.Cochlea’s stria damage makes alterations in the composition of endolymph. This study aimed to confirm rubella infection using PCR and serological tests in patients with CRS who were clinically deaf. A suspected CRS reported was a 2-month-old patient with an unclear response to surround sound. The patient had been already diagnosed with congenital cataracts before. Prenatal, perinatal and postnatal history was evaluated. Hearing screen...
INDONESIAN JOURNAL OF CLINICAL PATHOLOGY AND MEDICAL LABORATORY, 2019
Hearing loss in newborns or congenital deafness can be caused by the development of parts of the ... more Hearing loss in newborns or congenital deafness can be caused by the development of parts of the auditory system. Congenital deafness is often associated with infections such as toxoplasmosis, rubella, cytomegalovirus (CMV), and herpes (TORCH). Deafness is very difficult to find early. Examination of inspection methods that are easy and fast. Efforts to conduct early detection are determined through the Newborn Hearing Screening (NHS) program. Otoacoustic Emission (OAE) and Automated Auditory Brainstem Response (AABR) checks are raw materials for early detection. Congenital deafness often occurs with pregnancy infections with viruses such as rubella. Rubella infection during pregnancy, especially during the first trimester often causes Congenital Rubella Syndrome (CRS). Rubella infection is often double with other causes, namely Toxoplasama, CMV and Herpes. Serological examination can be done by examining Rubella IgG and IgM antibodies. Examination of rubella infection with serologi...
Indian Journal of Otolaryngology and Head & Neck Surgery, 2018
Indian Journal of Otolaryngology and Head & Neck Surgery, 2018
Tinnitus is the perception of hearing the sound without any sound stimulus. It is a symptom of ab... more Tinnitus is the perception of hearing the sound without any sound stimulus. It is a symptom of abnormality in a form of conductive disorder when it comes from the outer ear canal and middle ear. A tinnitus complaint has a normal hearing threshold but it has been not fully recognized its causes. Thus, an objective evaluation is needed to locate the abnormality by using OAE and BERA test. To analyze the association of TEOAE, DPOAE, and BERA to locate cochlear and retrocochlear disorders in tinnitus patients with normal hearing threshold. The study was conducted from August to November 2010 until the number of samples was fulfilled in Outpatient Clinic and
F1000Research
Background: The purpose of this study was to obtain data on the prevalence of specialist doctors ... more Background: The purpose of this study was to obtain data on the prevalence of specialist doctors and Otorhinolaryngology-Head and Neck Surgery (ORL-HNS) residents in Indonesia who suffered from Coronavirus disease 2019 (COVID-19) after receiving the second dose of COVID-19 vaccination using the Sinovac vaccine (CoronaVac) and the length of time infected with COVID-19 after the second Sinovac vaccination. Methods: We performed a descriptive observational study, using a cross-sectional design. Data collection took place between August 2021 and October 2021. The respondents in this study included specialist doctors and ORL-HNS residents who worked in various hospitals in Indonesia who had received the second dose of the Sinovac vaccination. Data collection was performed by means of Self-reporting Online Survey Platform (Google Form). Results: This study included 1,530 respondents, and 54.2% of respondents were women. Respondents consisted of 68.6% ORL-HNS doctors and the rest were resi...
International Journal of Pediatric Otorhinolaryngology
eJournal Kedokteran Indonesia
This study’s objectives were to investigate factors affecting the adverse events of the COVID-19 ... more This study’s objectives were to investigate factors affecting the adverse events of the COVID-19 vaccine in Indonesia among health care workers and compare adverse events following SARS-CoV-2 vaccine using CoronaVac as the first and second dose and Moderna used as the booster third dose. A cross-sectional study was conducted using the Self-reporting Online Survey Platform (Google Form) from August to October 2021. Subjects included in the study were ENT specialists and residents all over Indonesia who had been vaccinated with both doses of CoronaVac COVID-19 vaccine and Moderna COVID-19 vaccine as a booster dose. Among a total of 1394 participants, 51.2% and 43.7% of subjects experienced adverse events following the first and second dose of the CoronaVac vaccine. Adverse events are significantly higher following the third dose of Moderna vaccine (95.3%) with p-value <0.001, odds ratio (OR) 26.63 (95% CI 19.87-35.7). Adverse events following the CoronaVac vaccine were significantl...
Proceedings of Meetings on Acoustics, 2019
Pure-tone audiometry as a gold standard is difficult to do in several places in Indonesia due to ... more Pure-tone audiometry as a gold standard is difficult to do in several places in Indonesia due to problems related to access, referral systems, and costs. Therefore, the examiner relies on the whisper test as a screening test. In this study, we evaluated the method of the whisper test by modifying the distance in order to make the procedure practical, simple and easy to perform in a smaller room with large groups. A crosssectional study between the modified whisper test and the reference test (pure-tone audiometry) was conducted on 618 selected participants. Based on diagnostic and screening test evaluation, it was known that sensitivity and specificity of the modified-distance whispered voice test were 13.43% and 99.27%, respectively. While the test yielded high PPV (69.23%) and NPV (90.41%) for a screening test. The likelihood ratio results were 18.50 for positive and 0.87 for negative. The other parameter results were 21.22 (DOR), 89.97% (diagnostic effectiveness), 10.03% (misclassification rate), and 0.13 (Youden's Index). This hearing screening method will help identify more hearing impairments for a considerable population, helping in referral planning.
Indian Journal of Forensic Medicine & Toxicology, 2021
Objective: socializing hearing loss examination and early detection to patients and their familie... more Objective: socializing hearing loss examination and early detection to patients and their families in deaf type B schools. Methods: A community service program in the form of socialization was performed to the family of patients with hearing loss in deaf school type B, Surabaya, Indonesia. Pretest and posttest were conducted to determine the initial understanding and post socialization knowledge of these people. We also asked the participants to fill on a questionnaire regarding the possible causes of the hearing loss (family history, drug use, history of disease, and history of head trauma). Results: Based on the summary of pretest and posttest from the participants, an increase in participants' knowledge of hearing lost was found. This activity was attended by 90 family members of 37 patients with hearing loss. Pre and post test results. The results of the questionnaire showed that 94.59% of the patients came from Javanese ethnicity. As many as 21.62% of patients had a family history of hearing loss, and even 2 patients had a father, mother, and sibling with hearing loss. A total of 18.92% had a history of using ototoxic drugs, 16.22% had a history of maternal Rubella infection during pregnancy, and 2.7% had a history of head trauma. Conclusion: Socialization program was effective to increase knowledge of congenital hearing loss for family of deaf schoolchildren. The result of the questionnaire showed that deaf schoolchildren had several risk factors for the occurrence of hearing loss. Similar program can be performed in communities in other areas to increase prevention and early detection of hearing loss in Indonesia.
Jurnal Layanan Masyarakat (Journal of Public Services), 2021
Hearing loss can disrupt communication, which has an impact on social, school, and work environme... more Hearing loss can disrupt communication, which has an impact on social, school, and work environments. Early detection and management of hearing loss can prevent it. The community is hoped to be contributed by raising awareness of hearing loss and its prevention. Therefore, educational activities in the form of counseling and training were carried out for various groups in Kalibaru Kulon village, Kalibaru Sub District, Banyuwangi District, East Java. The aim of the counseling and training on early detection of hearing loss for medical personnel is to increase their knowledge and skills at the Public Health Center (Puskesmas) to perform early detection and management of hearing loss. The purpose of hearing health counseling activities for “Satya Kencana” youth organizations is to increase their knowledge as a strategic age in the community to engage in early detection of hearing loss activities in the community. The training of medical personnel was conducted through lectures, practic...
Indian Journal of Forensic Medicine & Toxicology, 2021
Objective: Analyzing the association between pure tone audiometry and distortion of otoacoustic e... more Objective: Analyzing the association between pure tone audiometry and distortion of otoacoustic emission (DPOAE) in students after shooting practice.
Infectious Disease Reports, 2020
Background: Definition of Congenital Ruben Syndrome (CRS): a disease caused by rubella virus infe... more Background: Definition of Congenital Ruben Syndrome (CRS): a disease caused by rubella virus infection. Routine surveil- lance of CRS is part of a government pro- gram in documenting the incidence of CRS so that infants with CRS are diagnosed promptly and receive appropriate care. Objective: This study aims to repodiology Outpatient General Hospital Dr. Soetomo Surabaya.Method: A descriptive study from CRS surveillance data for the period from January 1st until December 31rd, 2015. Data was from Infants who came to the Audiology Outpatient General Hospital Dr. Soetomo Surabaya and did hearing and serological examination. Results: A total of 65 infants were involved in surveillance. The highest num- ber of patients was the age group 1- <3 years (21 patients, 31.2%). A total of 36 patients (55.4%) were male, 45 babies (69.2%) were suspected of suffering from CRS with 2 infants (3.1%) classified as a laboratory-confirmed CRS. Hearing abnor- malities were found in 36 infants (55.4%)....
Journal of Community Medicine and Public Health Research, 2020
Presbycusis is a disease that can befall the elderly, caused by a multifactorial process that sho... more Presbycusis is a disease that can befall the elderly, caused by a multifactorial process that should be allowed to disrupt communication and social life and cause mental disorders. According to WHO the proportion of the elderly population rises rapidly which is estimated in 2025, there are about 1,2 billion elderly people with a risk of presbycusis. Mr.S was 84 years old, married and had 2 children, complained of hearing loss since 10 years ago on the patient's left ear. The decline in hearing occurred gradually, giving the last 4 years after his wife's death. Patients was taken to Otorhinolaryngologist and expressed age-related hearing impairment and was advised to use hearing aids. Patients are not routinely using hearing aids. In addition, patients have hypertension and heart disease. Patients consumed Captopril 2x1 tablets, Fundifar 2x1, Furosemide 1x40 mg and Fargoxin 1x0.25 mg. Patients do not routinely consumed cardiac medicine and used hearing aids. From the results ...
Folia Medica Indonesiana, 2020
Long-term exposure to aminoglycoside such as kanamycin to cochlear cells is known to be associate... more Long-term exposure to aminoglycoside such as kanamycin to cochlear cells is known to be associated with damage to outer hair cells in the organ Corti and type 1 sensory hair cells in the vestibular organs which ultimately causes permanent damage to hair cells. Hair cell damage occurs from the basal cochlea (high frequency area) to the apex cochlea (low frequency area) and followed by damage from the auditory nerve. Evaluation of cochlear dysfunction on multidrug resistant tuberculosis (MDR TB) patients have been rarely reported in the literature based on distortion product otoacoustic emission (DPOAE). Objectives: To prove cochlear dysfunction after kanamycin injection in MDR TB patient based on DPOAE examination of the overall frequencies and specific frequency. This was an observational longitudinal analytic with pre and post design without control group conducted in the infection division of MDR TB Outpatients Pulmonology Department and Otorhinolaryngology Community division of O...
Journal of Community Medicine and Public Health Research, 2020
Congenital deafness is a hearing loss disorder that occurs at birth and is one of the disorders t... more Congenital deafness is a hearing loss disorder that occurs at birth and is one of the disorders that can cause complications when it is not treated.1 Children with hearing loss will face difficulties such as poor development outcomes, including poor speech and language skills and face difficulties with cognition and social-emotional interactions. Early intervention has been proven to be one of the most important factors leading to good outcomes for children with congenital hearing loss.2 This case study is intended to highlight the importance of early case detections, early interventions and how family support plays a crucial role in the development of children with hearing loss. With the support of her family, Ms. DRP has gone through several speech and hearing therapies since her surgery and has proven to have an above-average linguistic abilities, showing that early problem detection does not hinder the development and achievement of children with congenital hearing loss.
Journal of Community Medicine and Public Health Research, 2020
The high number of patients who come for ear therapy with massage skills, the P3T Center intends ... more The high number of patients who come for ear therapy with massage skills, the P3T Center intends to carry out an observational screening of ear therapy. This screening aims to find out how the diagnostic method and application of ear therapy with massage skills and the benefits of ear therapy to overcome the problem of hearing loss (hearing impairment). This screening design uses an observational method in which the researcher makes observations and interviews with respondents. Data collection techniques were carried out by looking at the results of the examination of respondents' hearing tests and the results of interviews with respondents. Patient therapy results in 18 people (60%) no progress or the same as the original condition. this shows that therapy can be said to be ineffective in curing ear disorders. The results of the audiometry examination of the right and left ear stated that none of the patients was normal. Even though there are patients who claim to be able to he...
Oto Rhino Laryngologica Indonesiana, Jun 27, 2019
Background: Presbycusis is a hearing loss due to the degeneration process in elderly people of 65... more Background: Presbycusis is a hearing loss due to the degeneration process in elderly people of 65 years old and beyond, characterized by a decrease in hearing sensitivity in both ears. Reactive oxygen species (ROS) are assumed to have an important role in the pathogenesis of presbycusis. Purpose: To find out the correlation between ROS levels in plasma and hearing threshold levels in presbycusis patients.
Oto Rhino Laryngologica Indonesiana, 2018
Background: Hearing loss is one of the congenital abnormalities frequently found in children, whi... more Background: Hearing loss is one of the congenital abnormalities frequently found in children, which is followed by delayed speech and language development. The majority of cases have unknown causes of hearing loss resulting in late diagnosis. Newborn Hearing Screening Program (NHSP) recommended Otoacoustic Emissions (OAE) and Brainstem Evoked Response Audiometry (BERA) as detection of hearing loss in infants and children. Objective: To obtain the prevalence and description of sensorineural hearing loss in infants and children. Method: A retrospective descriptive study of infants underwent OAE and BERA between 2011-2013 at Dr Soetomo Hospital. The degree of hearing loss was according to the International Standard Organization (ISO). Result: A total number of 552 infant and children were examined, and 377 (68%) were detected with sensorineural hearing loss (SNHL). This group of SNHL consisted of 199 males (52.79%) and 178 females (47.21%). The largest age group was 12 to 36 months, re...
Indonesian Journal of Tropical and Infectious Disease, 2020
Rubella infections in pregnant women, especially during the first trimester, often lead to manife... more Rubella infections in pregnant women, especially during the first trimester, often lead to manifest as congenital rubella syndrome (CRS). This syndrome consists of several inherited disorders such as deafness, cataracts, and cardiac abnormalities. Deafness is the most common manifestation of CRS, 70-90% of all cases with deafness type are sensory neural deafness. The mechanism of hearing loss due to rubella virus is caused by hypoxia resulting from endothelial vascular damage in cochlea, followed by cell death in the organ of Corti and stria vascularis.Cochlea’s stria damage makes alterations in the composition of endolymph. This study aimed to confirm rubella infection using PCR and serological tests in patients with CRS who were clinically deaf. A suspected CRS reported was a 2-month-old patient with an unclear response to surround sound. The patient had been already diagnosed with congenital cataracts before. Prenatal, perinatal and postnatal history was evaluated. Hearing screen...
INDONESIAN JOURNAL OF CLINICAL PATHOLOGY AND MEDICAL LABORATORY, 2019
Hearing loss in newborns or congenital deafness can be caused by the development of parts of the ... more Hearing loss in newborns or congenital deafness can be caused by the development of parts of the auditory system. Congenital deafness is often associated with infections such as toxoplasmosis, rubella, cytomegalovirus (CMV), and herpes (TORCH). Deafness is very difficult to find early. Examination of inspection methods that are easy and fast. Efforts to conduct early detection are determined through the Newborn Hearing Screening (NHS) program. Otoacoustic Emission (OAE) and Automated Auditory Brainstem Response (AABR) checks are raw materials for early detection. Congenital deafness often occurs with pregnancy infections with viruses such as rubella. Rubella infection during pregnancy, especially during the first trimester often causes Congenital Rubella Syndrome (CRS). Rubella infection is often double with other causes, namely Toxoplasama, CMV and Herpes. Serological examination can be done by examining Rubella IgG and IgM antibodies. Examination of rubella infection with serologi...
Indian Journal of Otolaryngology and Head & Neck Surgery, 2018
Indian Journal of Otolaryngology and Head & Neck Surgery, 2018
Tinnitus is the perception of hearing the sound without any sound stimulus. It is a symptom of ab... more Tinnitus is the perception of hearing the sound without any sound stimulus. It is a symptom of abnormality in a form of conductive disorder when it comes from the outer ear canal and middle ear. A tinnitus complaint has a normal hearing threshold but it has been not fully recognized its causes. Thus, an objective evaluation is needed to locate the abnormality by using OAE and BERA test. To analyze the association of TEOAE, DPOAE, and BERA to locate cochlear and retrocochlear disorders in tinnitus patients with normal hearing threshold. The study was conducted from August to November 2010 until the number of samples was fulfilled in Outpatient Clinic and