Oliver Perez - Academia.edu (original) (raw)

Papers by Oliver Perez

Research paper thumbnail of Algunos Porques Cognitivos Del Analisis Semiotico Una Aproximacion a Las Confluencias Entre Semiotica y Psicologia Cognitiva

Servicio de Publicaciones, 2012

Research paper thumbnail of Evaluation of the immunogenicity in humans of a new adjuvanted anti-allergic therapeutic vaccine

Journal of Allergy and Clinical Immunology, 2018

Research paper thumbnail of Corresponding author 1 st International and 2 nd National Workshop on Vaccine Adjuvants

Research paper thumbnail of Actas-III Congreso Internacional Latina de Comunicación Social-III CILCS-Universidad de La Laguna, diciembre 2011 Actas-III Congreso Internacional Latina de Comunicación Social-III CILCS-Universidad de La Laguna, diciembre 2011 Página 2

Resumen En los últimos años el concepto de narrativa transmediática ha emergido como un objeto de... more Resumen En los últimos años el concepto de narrativa transmediática ha emergido como un objeto de estudio central para la comprensión de la nueva narrativa televisiva. Habitualmente este tipo de estudios se han centrado en la ficción, sin embargo géneros híbridos como los reality game shows, que también construyen un relato, han establecido sinergias muy significativas con la web (entre otros medios) para enriquecer el mundo narrativo que ofrecen a los espectadores. Por lo tanto, para entender en toda su extensión el fenómeno de la narrativa transmediática también es necesario analizar las estrategias de expansión de estos programas. En este contexto, esta comunicación plantea como objetivo analizar la expansión transmediática de dos de los reality game shows más populares a nivel internacional y que han utilizado estas estrategias de forma sustancial: Operación Triunfo y American Idol. Para abordar este objetivo se ha desarrollado una metodología basada en el análisis textual, que ...

Research paper thumbnail of Géneros de juegos y videojuegos: una aproximación desde diversas perspectivas teóricas

Comunicació: Revista de Recerca i d'Anàlisi, 2011

Si la forma como, desde ninos, construimos universos de valores y damos sentido a nuestras vidas ... more Si la forma como, desde ninos, construimos universos de valores y damos sentido a nuestras vidas esta indisolublemente unida a los medios y las obras de la cultura de masas, la teoria y metodologia del analisis del videojuego requieren, hoy en dia, un desarrollo en profundidad. En este contexto, una cuestion fundamental es la constuccion de taxonomias precisas sobre los diversos generos de videojuego. Con el objetivo de contribuir a esta tarea, en este articulo se presenta una propuesta de taxonomia modular de generos de videojuego, a traves de dos procedimientos distintivos: la busqueda de criterios de clasificacion plurales y la articulacion de perspectivas teoricas tambien plurales. Los fundamentos teoricos sobre los cuales se construye el trabajo son la psicologia y la antropologia del juego, la ludologia y la teoria del videojuego y la historia del juego.

Research paper thumbnail of La construcción televisiva de la deliberación política. Análisis comparativo de programas informativos y de infotainment The representation of political deliberation in television. A comparative analysis of informative and infotainment programmes

According to J. Blumler and D. Kavanagh, since the mid nineties we are in the Third Age of Politi... more According to J. Blumler and D. Kavanagh, since the mid nineties we are in the Third Age of Political Communication, where the emergence of Internet, digital TV and infotainment and the increasing awareness of political disaffection have converged. Therefore, it is necessary to review the role of television in this new era of political communication, and at the same time we need to adapt our theoretical and methodological tools to the new reality of TV and political communication. In this context, the purpose of this research is defining a model of analysis for the study of TV construction

Research paper thumbnail of Mucosal approaches in Neisseria Vaccinology

VacciMonitor, 2009

Finlay Institute is one of the pioneering organizations in Neisseria Vaccinology mainly by its co... more Finlay Institute is one of the pioneering organizations in Neisseria Vaccinology mainly by its contribution to N. meningitidis serogroup B outer membrane-based bivalent vaccine, VA-MENGOC-BC® (4). This was applied, intramuscularly, in more than 60 million doses. Only 10.7 millions of them correspond to Cuban young adults, children, and infants. However, most dangerous or commensally Neisseria strains enter and establish in the mucosa, where the secretory (S) IgA is the main specific guardian and is mainly induced by mucosal routes (5). In addition, colonization of young children by N. lactamica has been implicated in naturally-acquired meningococcal immunity. Nonetheless, more attention was dedicated to systemic response against Neisseria diseases. Contrary, less attention was dedicated to mucosal immune response. In addition, few mucosal vaccines exist predominantly due to the absent of safe mucosal adjuvants.

Research paper thumbnail of NATURAL Neissera DERIVE PROTEOLIPOSOME AND COCHLEATE AS POTENT VACCINE ADJUVANTS

Summary Proteoliposome (AFPL1) and its derivated - Cochleate (AFCo1) contain immunopotentiating a... more Summary Proteoliposome (AFPL1) and its derivated - Cochleate (AFCo1) contain immunopotentiating and immunomodulatory properties and delivery system capacities required for a good adjuvant. In addition, they permit package of multimeric antigens and synergistic pathogen-associate molecular pattern essential to stimulate innate immunity. AFPL1 and AFCo1 is produce in GMP condition at industrial scale at Finlay Institute. Both, AFPL1 and AFCo1 contain protective anti Neisseria components. AFPL1 was used for several years as main adjuvant and antigen of Men BC combine vaccine where induces a preferential Th1 pattern of immune response. That is why, it is using in formulation against allergen to overcome the Th2 response induced by them. AFCo1 is more efficient that AFPL1 mainly for mucosal routes and a nasal vaccine is in preclinical stage of development. Preliminary results against Malaria and sexual transmitted disease are very promising. AFPL1 and AFCo1 acting directly as vaccines or...

Research paper thumbnail of El lenguaje videolúdico : análisis de la significación del videojuego

"Desde el nacimiento del videojuego como producto de la cultura de masas en los años setenta... more "Desde el nacimiento del videojuego como producto de la cultura de masas en los años setenta, las perspectivas de análisis que han predominado sobre este se han basado en su consideración como un objeto tecnológico, como producto comercial de una nueva industria emergente, como un medio de entretenimiento, como un recurso educativo, como una influencia sobre el comportamiento de los jóvenes y, más recientemente, como un objeto cultural. Pero el diseño de videojuegos trae también consigo un nuevo lenguaje, el lenguaje del diseño de reglas de juego y de estructuras y dinámicas de interactividad lúdica. El videojuego puede y debe ser estudiado también como una obra comunicativa. Con la finalidad de realizar una contribución a esta tarea, este libro propone una exploración sobre las estructuras y los recursos expresivos que hacen del diseño de videojuegos un nuevo lenguaje, y aporta una metodología de análisis del videojuego como obra comunicativa. Paralelamente, en el trabajo se deja de manifiesto que no solo los denominados serious games o persuasive games tienen «mensaje», sino que detrás de todo videojuego, incluidos los videojuegos del mainstream comercial, hay un discurso, una determinada visión del mundo, un cierto punto de vista sobre qué es la «victoria» y qué es la «derrota», y cómo se llega a cada una de ellas. En el desarrollo del libro se integran aspectos de Ludología, Semiótica, Narratología y Psicología Cognitiva, y se aborda el análisis de algunos de los videojuegos más populares, entre ellos Los Sims, Grand Theft Auto, Half-Life y Bioshock. Para finalizar, se propone un estudio en profundidad sobre los videojuegos del diseñador Fumito Ueda, Ico y Shadow of the Colossus."

Research paper thumbnail of Identificación in silico del mimetismo molecular entre epitopes T de Neisseria meningitidis B y el proteoma humano

Revista Peruana de Medicina Experimental y Salud Pública, 2014

Research paper thumbnail of What are teens doing with media? An ethnographic approach for identifying transmedia skills and informal learning strategies

Digital Education Review, 2020

The emergence of new media, devices, narratives and practices has compelled media literacy schola... more The emergence of new media, devices, narratives and practices has compelled media literacy scholars and professionals to review their theoretical frameworks and methodological approaches. Based on a new conception – ‘transmedia literacy’ – that moves from traditional media literacy to informal learning and participatory cultures practices, the research program behind the present article tries to understand how new generations are doing things with media outside schools and how they learnt to do the things they do. The article begins by describing the transformations of media literacy in recent years as a consequence of the mutations of the media ecology and, in that context, proposes a methodological approachfor analysing the acquisition of transmedia skills in informal learning environments by teens. The article describes, analyses and evaluates the development and initial implementation of this methodology working with teenagers in a high-school in NAME CITY. It ends with a Resear...

Research paper thumbnail of 영국의 금융 분쟁과 해결을 위한 대안 시스템

Sogang Journal of Law and Business, 2013

Research paper thumbnail of Financial Disputes in the Uk and Alternative Systems for Resolution

Sogang Journal of Law and Business, 2013

Research paper thumbnail of Recessionary games: Video games and the social imaginary of the Great Recession (2009–2015)

Convergence: The International Journal of Research into New Media Technologies, 2017

How do the most popular video games in recent years contribute to the construction of the social ... more How do the most popular video games in recent years contribute to the construction of the social imaginary of the Great Recession? The discursive struggles over the definition of crucial aspects of the recession such as austerity, the heroic ethos to face precariousness and being anti-establishment are being played not only in the political arena and ‘serious’ news genres but also in the narrations of popular culture and video games. Thus, critical analysis of the social resonances of video games on the Great Recession is a relevant exercise not only academically but also socially. To address this question, this article proposes an analysis of bestselling video games from 2009 to 2015, based on cultural studies and game studies. The analysis is organized in three case studies: (a) post-apocalyptic video games and their potential resonances regarding austerity and precariousness; (b) video games, neo-liberalism and counter neo-liberal views; and (c) video games and the representation...

Research paper thumbnail of Video Games, Dystopia, and Neoliberalism: The Case of BioShock Infinite

Games and Culture, 2017

An ideological analysis of video games should include both the narrative and ludic dimensions, si... more An ideological analysis of video games should include both the narrative and ludic dimensions, since there can be frictions between these two dimensions and they can even contradict one another. This article’s main aim is to analyze BioShock Infinite, an illustrative case study of these conflicts. On the one hand, it is a video game that portrays a dystopian narrative, aligning itself with this genre’s critical progressive tradition; on the other hand, its gameplay has an accentuated neoliberal bent. The analysis of BioShock Infinite also helps us to critically discuss certain trends in game design in contemporary mainstream video games that connect with and reinforce neoliberal values.

Research paper thumbnail of Framing Sálvame: Public debates on taste, quality and television in Spain

Communications, 2018

The main aim of this article is to analyze the social circulation of discourses on non-hegemonic ... more The main aim of this article is to analyze the social circulation of discourses on non-hegemonic cultural practices, in particular, on what is called “trash TV”, and how they are connected to struggles over cultural and social hierarchies. To do so, it takes a specific event as starting point: the injunction that the CNMC (the Spanish broadcasting regulatory body) filed against Mediaset (a commercial TV operator) to adjust the contents of Sálvame Diario (a celebrity gossip program frequently associated with “trash TV”) to the requirements of what is known as the “child protection time slot”. This paper uses constructionist framing to analyze how this event was discussed by different social actors. Our analysis shows that while the CNMC and the press painted the conflict as a legal issue, Sálvame and social media users focused their discussion on the social acceptability of celebrity gossip media and their viewers (specifically working-class women).

Research paper thumbnail of The immune profile induced is crucial to determine the effects of immunocastration over gonadal function, fertility, and GnRH-I expression

American journal of reproductive immunology (New York, N.Y. : 1989), 2018

Immunocastration or vaccination against the GnRH-I hormone is a promising alternative to reproduc... more Immunocastration or vaccination against the GnRH-I hormone is a promising alternative to reproductive control in different animal species. Given the low immunogenicity of this hormone, the use of adjuvants becomes necessary. This study evaluated the effects of three adjuvants that induce different immune response profiles over gonadal function, fertility, and expression of GnRH-I. Female mice (n = 6) were vaccinated at days 1 and 30 with a recombinant antigen for immunocastration and different adjuvants that induced preferentially Th1/Th2, Th2, and Th1 immune profiles. Th1/Th2 response is the most efficient to block reproductive activity in vaccinated animals, reducing the number of luteal bodies and pre-ovulatory follicles. Th2 and Th1/Th2 responses induced an increase in GnRH-I at the hypothalamus. The immune profile induced by different adjuvants is essential on the effects over fertility, gonadal function, and hypothalamic GnRH-I expression in immunocastrated animals.

Research paper thumbnail of Safety of a proteoliposome from Neisseria meningitides as adjuvant for a house dust mite allergy vaccine

Journal of Immunotoxicology, 2017

Research paper thumbnail of ‘Choose, collect, manage, win!’: Neoliberalism, enterprising culture and risk society in video game covers

Convergence: The International Journal of Research into New Media Technologies, 2016

This article aims to identify the relationship between video games and neoliberal values. To fulf... more This article aims to identify the relationship between video games and neoliberal values. To fulfil this aim, it analyses the covers of the 20 top-selling video games in the United States each year from 2010 to 2014 (a total of 80 different games). Video game covers are a type of paratext, that is, texts that accompany another text to promote it and to guide its reading. Thus, video game covers choose and highlight some of the games’ features over others, and by doing that they construct a discourse. In this article, it is argued that regardless of genre, the covers analysed convey and promote neoliberal values, such as freedom and choice, entrepreneurship, consumption and accumulation of goods, customization, novelty, individualism and meritocracy. This promotion of neoliberal values is combined with an appeal to the concerns of ‘risk society’. Thus, the covers of the top-selling video games play on fears linked to the new context created by the economic crisis while at the same ti...

Research paper thumbnail of Indie or Mainstream? Tensions and Nuances between the Alternative and the Mainstream in Indie Games

Research paper thumbnail of Algunos Porques Cognitivos Del Analisis Semiotico Una Aproximacion a Las Confluencias Entre Semiotica y Psicologia Cognitiva

Servicio de Publicaciones, 2012

Research paper thumbnail of Evaluation of the immunogenicity in humans of a new adjuvanted anti-allergic therapeutic vaccine

Journal of Allergy and Clinical Immunology, 2018

Research paper thumbnail of Corresponding author 1 st International and 2 nd National Workshop on Vaccine Adjuvants

Research paper thumbnail of Actas-III Congreso Internacional Latina de Comunicación Social-III CILCS-Universidad de La Laguna, diciembre 2011 Actas-III Congreso Internacional Latina de Comunicación Social-III CILCS-Universidad de La Laguna, diciembre 2011 Página 2

Resumen En los últimos años el concepto de narrativa transmediática ha emergido como un objeto de... more Resumen En los últimos años el concepto de narrativa transmediática ha emergido como un objeto de estudio central para la comprensión de la nueva narrativa televisiva. Habitualmente este tipo de estudios se han centrado en la ficción, sin embargo géneros híbridos como los reality game shows, que también construyen un relato, han establecido sinergias muy significativas con la web (entre otros medios) para enriquecer el mundo narrativo que ofrecen a los espectadores. Por lo tanto, para entender en toda su extensión el fenómeno de la narrativa transmediática también es necesario analizar las estrategias de expansión de estos programas. En este contexto, esta comunicación plantea como objetivo analizar la expansión transmediática de dos de los reality game shows más populares a nivel internacional y que han utilizado estas estrategias de forma sustancial: Operación Triunfo y American Idol. Para abordar este objetivo se ha desarrollado una metodología basada en el análisis textual, que ...

Research paper thumbnail of Géneros de juegos y videojuegos: una aproximación desde diversas perspectivas teóricas

Comunicació: Revista de Recerca i d'Anàlisi, 2011

Si la forma como, desde ninos, construimos universos de valores y damos sentido a nuestras vidas ... more Si la forma como, desde ninos, construimos universos de valores y damos sentido a nuestras vidas esta indisolublemente unida a los medios y las obras de la cultura de masas, la teoria y metodologia del analisis del videojuego requieren, hoy en dia, un desarrollo en profundidad. En este contexto, una cuestion fundamental es la constuccion de taxonomias precisas sobre los diversos generos de videojuego. Con el objetivo de contribuir a esta tarea, en este articulo se presenta una propuesta de taxonomia modular de generos de videojuego, a traves de dos procedimientos distintivos: la busqueda de criterios de clasificacion plurales y la articulacion de perspectivas teoricas tambien plurales. Los fundamentos teoricos sobre los cuales se construye el trabajo son la psicologia y la antropologia del juego, la ludologia y la teoria del videojuego y la historia del juego.

Research paper thumbnail of La construcción televisiva de la deliberación política. Análisis comparativo de programas informativos y de infotainment The representation of political deliberation in television. A comparative analysis of informative and infotainment programmes

According to J. Blumler and D. Kavanagh, since the mid nineties we are in the Third Age of Politi... more According to J. Blumler and D. Kavanagh, since the mid nineties we are in the Third Age of Political Communication, where the emergence of Internet, digital TV and infotainment and the increasing awareness of political disaffection have converged. Therefore, it is necessary to review the role of television in this new era of political communication, and at the same time we need to adapt our theoretical and methodological tools to the new reality of TV and political communication. In this context, the purpose of this research is defining a model of analysis for the study of TV construction

Research paper thumbnail of Mucosal approaches in Neisseria Vaccinology

VacciMonitor, 2009

Finlay Institute is one of the pioneering organizations in Neisseria Vaccinology mainly by its co... more Finlay Institute is one of the pioneering organizations in Neisseria Vaccinology mainly by its contribution to N. meningitidis serogroup B outer membrane-based bivalent vaccine, VA-MENGOC-BC® (4). This was applied, intramuscularly, in more than 60 million doses. Only 10.7 millions of them correspond to Cuban young adults, children, and infants. However, most dangerous or commensally Neisseria strains enter and establish in the mucosa, where the secretory (S) IgA is the main specific guardian and is mainly induced by mucosal routes (5). In addition, colonization of young children by N. lactamica has been implicated in naturally-acquired meningococcal immunity. Nonetheless, more attention was dedicated to systemic response against Neisseria diseases. Contrary, less attention was dedicated to mucosal immune response. In addition, few mucosal vaccines exist predominantly due to the absent of safe mucosal adjuvants.

Research paper thumbnail of NATURAL Neissera DERIVE PROTEOLIPOSOME AND COCHLEATE AS POTENT VACCINE ADJUVANTS

Summary Proteoliposome (AFPL1) and its derivated - Cochleate (AFCo1) contain immunopotentiating a... more Summary Proteoliposome (AFPL1) and its derivated - Cochleate (AFCo1) contain immunopotentiating and immunomodulatory properties and delivery system capacities required for a good adjuvant. In addition, they permit package of multimeric antigens and synergistic pathogen-associate molecular pattern essential to stimulate innate immunity. AFPL1 and AFCo1 is produce in GMP condition at industrial scale at Finlay Institute. Both, AFPL1 and AFCo1 contain protective anti Neisseria components. AFPL1 was used for several years as main adjuvant and antigen of Men BC combine vaccine where induces a preferential Th1 pattern of immune response. That is why, it is using in formulation against allergen to overcome the Th2 response induced by them. AFCo1 is more efficient that AFPL1 mainly for mucosal routes and a nasal vaccine is in preclinical stage of development. Preliminary results against Malaria and sexual transmitted disease are very promising. AFPL1 and AFCo1 acting directly as vaccines or...

Research paper thumbnail of El lenguaje videolúdico : análisis de la significación del videojuego

"Desde el nacimiento del videojuego como producto de la cultura de masas en los años setenta... more "Desde el nacimiento del videojuego como producto de la cultura de masas en los años setenta, las perspectivas de análisis que han predominado sobre este se han basado en su consideración como un objeto tecnológico, como producto comercial de una nueva industria emergente, como un medio de entretenimiento, como un recurso educativo, como una influencia sobre el comportamiento de los jóvenes y, más recientemente, como un objeto cultural. Pero el diseño de videojuegos trae también consigo un nuevo lenguaje, el lenguaje del diseño de reglas de juego y de estructuras y dinámicas de interactividad lúdica. El videojuego puede y debe ser estudiado también como una obra comunicativa. Con la finalidad de realizar una contribución a esta tarea, este libro propone una exploración sobre las estructuras y los recursos expresivos que hacen del diseño de videojuegos un nuevo lenguaje, y aporta una metodología de análisis del videojuego como obra comunicativa. Paralelamente, en el trabajo se deja de manifiesto que no solo los denominados serious games o persuasive games tienen «mensaje», sino que detrás de todo videojuego, incluidos los videojuegos del mainstream comercial, hay un discurso, una determinada visión del mundo, un cierto punto de vista sobre qué es la «victoria» y qué es la «derrota», y cómo se llega a cada una de ellas. En el desarrollo del libro se integran aspectos de Ludología, Semiótica, Narratología y Psicología Cognitiva, y se aborda el análisis de algunos de los videojuegos más populares, entre ellos Los Sims, Grand Theft Auto, Half-Life y Bioshock. Para finalizar, se propone un estudio en profundidad sobre los videojuegos del diseñador Fumito Ueda, Ico y Shadow of the Colossus."

Research paper thumbnail of Identificación in silico del mimetismo molecular entre epitopes T de Neisseria meningitidis B y el proteoma humano

Revista Peruana de Medicina Experimental y Salud Pública, 2014

Research paper thumbnail of What are teens doing with media? An ethnographic approach for identifying transmedia skills and informal learning strategies

Digital Education Review, 2020

The emergence of new media, devices, narratives and practices has compelled media literacy schola... more The emergence of new media, devices, narratives and practices has compelled media literacy scholars and professionals to review their theoretical frameworks and methodological approaches. Based on a new conception – ‘transmedia literacy’ – that moves from traditional media literacy to informal learning and participatory cultures practices, the research program behind the present article tries to understand how new generations are doing things with media outside schools and how they learnt to do the things they do. The article begins by describing the transformations of media literacy in recent years as a consequence of the mutations of the media ecology and, in that context, proposes a methodological approachfor analysing the acquisition of transmedia skills in informal learning environments by teens. The article describes, analyses and evaluates the development and initial implementation of this methodology working with teenagers in a high-school in NAME CITY. It ends with a Resear...

Research paper thumbnail of 영국의 금융 분쟁과 해결을 위한 대안 시스템

Sogang Journal of Law and Business, 2013

Research paper thumbnail of Financial Disputes in the Uk and Alternative Systems for Resolution

Sogang Journal of Law and Business, 2013

Research paper thumbnail of Recessionary games: Video games and the social imaginary of the Great Recession (2009–2015)

Convergence: The International Journal of Research into New Media Technologies, 2017

How do the most popular video games in recent years contribute to the construction of the social ... more How do the most popular video games in recent years contribute to the construction of the social imaginary of the Great Recession? The discursive struggles over the definition of crucial aspects of the recession such as austerity, the heroic ethos to face precariousness and being anti-establishment are being played not only in the political arena and ‘serious’ news genres but also in the narrations of popular culture and video games. Thus, critical analysis of the social resonances of video games on the Great Recession is a relevant exercise not only academically but also socially. To address this question, this article proposes an analysis of bestselling video games from 2009 to 2015, based on cultural studies and game studies. The analysis is organized in three case studies: (a) post-apocalyptic video games and their potential resonances regarding austerity and precariousness; (b) video games, neo-liberalism and counter neo-liberal views; and (c) video games and the representation...

Research paper thumbnail of Video Games, Dystopia, and Neoliberalism: The Case of BioShock Infinite

Games and Culture, 2017

An ideological analysis of video games should include both the narrative and ludic dimensions, si... more An ideological analysis of video games should include both the narrative and ludic dimensions, since there can be frictions between these two dimensions and they can even contradict one another. This article’s main aim is to analyze BioShock Infinite, an illustrative case study of these conflicts. On the one hand, it is a video game that portrays a dystopian narrative, aligning itself with this genre’s critical progressive tradition; on the other hand, its gameplay has an accentuated neoliberal bent. The analysis of BioShock Infinite also helps us to critically discuss certain trends in game design in contemporary mainstream video games that connect with and reinforce neoliberal values.

Research paper thumbnail of Framing Sálvame: Public debates on taste, quality and television in Spain

Communications, 2018

The main aim of this article is to analyze the social circulation of discourses on non-hegemonic ... more The main aim of this article is to analyze the social circulation of discourses on non-hegemonic cultural practices, in particular, on what is called “trash TV”, and how they are connected to struggles over cultural and social hierarchies. To do so, it takes a specific event as starting point: the injunction that the CNMC (the Spanish broadcasting regulatory body) filed against Mediaset (a commercial TV operator) to adjust the contents of Sálvame Diario (a celebrity gossip program frequently associated with “trash TV”) to the requirements of what is known as the “child protection time slot”. This paper uses constructionist framing to analyze how this event was discussed by different social actors. Our analysis shows that while the CNMC and the press painted the conflict as a legal issue, Sálvame and social media users focused their discussion on the social acceptability of celebrity gossip media and their viewers (specifically working-class women).

Research paper thumbnail of The immune profile induced is crucial to determine the effects of immunocastration over gonadal function, fertility, and GnRH-I expression

American journal of reproductive immunology (New York, N.Y. : 1989), 2018

Immunocastration or vaccination against the GnRH-I hormone is a promising alternative to reproduc... more Immunocastration or vaccination against the GnRH-I hormone is a promising alternative to reproductive control in different animal species. Given the low immunogenicity of this hormone, the use of adjuvants becomes necessary. This study evaluated the effects of three adjuvants that induce different immune response profiles over gonadal function, fertility, and expression of GnRH-I. Female mice (n = 6) were vaccinated at days 1 and 30 with a recombinant antigen for immunocastration and different adjuvants that induced preferentially Th1/Th2, Th2, and Th1 immune profiles. Th1/Th2 response is the most efficient to block reproductive activity in vaccinated animals, reducing the number of luteal bodies and pre-ovulatory follicles. Th2 and Th1/Th2 responses induced an increase in GnRH-I at the hypothalamus. The immune profile induced by different adjuvants is essential on the effects over fertility, gonadal function, and hypothalamic GnRH-I expression in immunocastrated animals.

Research paper thumbnail of Safety of a proteoliposome from Neisseria meningitides as adjuvant for a house dust mite allergy vaccine

Journal of Immunotoxicology, 2017

Research paper thumbnail of ‘Choose, collect, manage, win!’: Neoliberalism, enterprising culture and risk society in video game covers

Convergence: The International Journal of Research into New Media Technologies, 2016

This article aims to identify the relationship between video games and neoliberal values. To fulf... more This article aims to identify the relationship between video games and neoliberal values. To fulfil this aim, it analyses the covers of the 20 top-selling video games in the United States each year from 2010 to 2014 (a total of 80 different games). Video game covers are a type of paratext, that is, texts that accompany another text to promote it and to guide its reading. Thus, video game covers choose and highlight some of the games’ features over others, and by doing that they construct a discourse. In this article, it is argued that regardless of genre, the covers analysed convey and promote neoliberal values, such as freedom and choice, entrepreneurship, consumption and accumulation of goods, customization, novelty, individualism and meritocracy. This promotion of neoliberal values is combined with an appeal to the concerns of ‘risk society’. Thus, the covers of the top-selling video games play on fears linked to the new context created by the economic crisis while at the same ti...

Research paper thumbnail of Indie or Mainstream? Tensions and Nuances between the Alternative and the Mainstream in Indie Games