Olivera Politeo - Academia.edu (original) (raw)

Papers by Olivera Politeo

Chemistry & Biodiversity

Plants

Sea fennel (Crithmum maritimum L.) is a wild-growing halophyte used in cuisine, traditional medic... more Sea fennel (Crithmum maritimum L.) is a wild-growing halophyte used in cuisine, traditional medicine or cosmetic products for its beneficial nutritive value and pleasant sensory characteristics. This study aimed to investigate sea fennel essential oils (EOs) from different parts of the plant (flowers, leaves and stems) and the corresponding hydrodistillation by-products (residual water) to validate their potential use and application in different industries. EOs were analyzed by gas chromatography coupled with mass spectrometry (GC-MS), while the phenolic profile of the residual water was analyzed by high-performance liquid chromatography (HPLC) and spectrophotometric methods. The EO analysis confirmed the presence of 14 compounds, dominated by sabinene (from 42.55 to 51.47%) and limonene (from 36.28 to 43.58%), while among the 12 detected phenolics, chlorogenic acid and its isomers (cryptochlorogenic and neochlorogenic acid) were found in the highest concentrations. Total phenolic,...

Essential Oils - Advances in Extractions and Biological Applications

This chapter will be described oxidative stress related to modern age illness as well as biologic... more This chapter will be described oxidative stress related to modern age illness as well as biological activity of essential oils and essential oil components in terms of their antioxidant activity. The importance of essential oils and their constituents in terms of protecting lipids and proteins from oxidation will also be explained. Alzheimer’s disease as a disease related to oxidative stress and strategies in their treatment by using essential oil components as cholinesterase inhibitors will also be described. As case studies will be pointed out medicinal plants, endemic Saturejasubspicata L., and widely used Menthapulegium L. growing in Bosnia and Herzegovina.

The antioxidant capacity of volatile aglycones from basil (Ocimum basilicum L.), laurel (Laurus n... more The antioxidant capacity of volatile aglycones from basil (Ocimum basilicum L.), laurel (Laurus nobilis L.) and clove (Syzygium aromaticum L. Merill et Perry) were examined. The volatile aglycones were extracted from their nonvolatile glycosidically bound compounds by enzymatic hydrolysis with β -glycosidasae enzyme. The chemical composition analyses of volatile aglycones were run on coupled system gas chromatography-mass spectrometry (GC-MS) with two different polarity columns. All volatile aglycone fractions have complex chemical compositions with identified aliphatic monoterpenic, sesquiterpenic, phenylpropanoid and norisoprenoid alcohols, ethers, acids, esters and carbonyl compounds. The major volatile aglycones are phenylpropanoid compounds. The major basil volatile aglycones are eugenol (44, 0 %) and chavicol (29, 5 %). Of laurel it is benzyl alcohol (63, 4 %), while the major clove volatile aglycone compound is eugenol (80, 5 %). The antioxidant capacity of isolated volatile ...

Reactive oxygen species (ROS) play a key role in the initiation and progression of many human dis... more Reactive oxygen species (ROS) play a key role in the initiation and progression of many human diseases. Superoxide anion radical (O2•-), arising continuously in the cells, is one of the most important and biologically relevant ROS radicals in living organisms. Superoxide dismutase (SOD) is an enzyme important in the process of cellular responses to stress conditions. Using WST spectrophotometric method, it is investigated the effect of insulin dependent diabetes mellitus (IDDM) on the SOD expression of tissues in aging rats. For this purpose, rat model for IDDM was established by streptozotocin application. The rats were randomly divided into 4 groups of animals: DM-2W (streptozotocin treated and sacrificed after 2 weeks of diabetes), control-2W (control group sacrificed after 2 weeks of the experiment), DM-1Y (streptozotocin treated and sacrificed after 1 year of diabetes) and control-1Y (control group sacrificed after 1 year of the experiment). Results showed overexpression of SOD...

Essential oils (EOs) are a complex mixtures containing volatile secondary metabolites with variou... more Essential oils (EOs) are a complex mixtures containing volatile secondary metabolites with various structures (terpenes, terpenoids, phenylpropanoids, and others). Their roles in plants vary from attracting pollinators to a defense against insects, food storage, and adaptations to harsh climate. Since ancient times, EOs are recognized for their medicinal value, representing a valuable source of biologically active compounds. EOs possess various activities including: antimicrobial, antiviral, antioxidant, antitumor, etc. They have also been used as perfumes, flavors for foods and beverages, remedies for the body and mind, and continue to be of paramount importance to date. Having a small molecular weight and lipid solubility, EO constituents possess the ability to pass the blood-brain barrier. Given the complexity of their chemical composition and ability to enter the brain, EOs and their constituents offer a promising strategy for the treatment of various neurological disorders. Alz...

Centaurea genus is one of the largest in the Asteraceae family, containing at least 400 species w... more Centaurea genus is one of the largest in the Asteraceae family, containing at least 400 species with about 80 of them listed in Croatia, comprising 27 endemics. Although these plants are morphologically well described, there are occasional doubts in their botanical systematics. Recent promising approaches in botanical systematics include also genome size and detailed chromosome characterization, using methods for visualization of specific DNA sequences on chromosomes as GC- or AT- rich regions and rDNA. The essential oil composition may be used in chemotaxonomy of the species that contributes previous data on morphology and cytogenetics. Centaurea solstitialis L. is world spread invasive species, originating from Middle East, and well known on medicinal use in Turkey ethno pharmacology. Detailed cytogenetic study and essential oil phytochemical profile of C. solstitialis from Croatia were reported for the first time. The cytogenetic characterization of Centaurea solstitialis was ass...

U radu je prikazano istraživanje kemijskog sastava i antioksidacijksog ucinka hlapljivih aglikona... more U radu je prikazano istraživanje kemijskog sastava i antioksidacijksog ucinka hlapljivih aglikona zacinskih biljaka bosiljka (Ocimum basilicum L.), lovora (Laurus nobilios L.) i klincica (Syzygium aromaticum L. Merill et Perry)

Chemistry & Biodiversity, 2018

Croatian Adriatic coast and islands are unique and distinctive area, thanks to its general featur... more Croatian Adriatic coast and islands are unique and distinctive area, thanks to its general features, unusual relief features, climate, complicated geological history and the relatively good preservation. Five world areas characterized by a Mediterranean climate, makes 2% of the world area which manages 20% of all known plant species, European Mediterranean with 10% of all known species in only 1.6% of the world surface. The genus Centaurea is one of the largest in the Asteraceae family, containing at least 400 species (even 700). East Anatolia and Transcaucasia are the primary center of the origin and diversification of the genus Centaurea, while the Mediterranean area, including the Balkan Peninsula, is the second one. In Croatia 79 Centaurea taxa have been listed, comprising 27 endemic species. Our preliminary chemical and biological observations, of extracts and volatiles isolated from few endemic species from Centaurea taxa, from Adriatic region showed that there are differences in chemical composition of volatile as well as differences of biological activities between the same species found on different localities. In order to determine whether these differences were generated from different ecological conditions or because of different structure on genetic level, cytogenetic analysis of selected plant species of Centaurea taxa from Croatia were made. Cytogenetic analysis was performed on a sampling covering 28 populations of 9 different Centaurea species among which 4 endemic for Croatia or Croatia and Italy. These species belong to 7 different sections and present four different basic chromosome numbers, x=8, 9, 10 and 11. Two ploidy levels, diploid and tetraploid, were also detected. The nuclear DNA amounts (2C DNA), assessed by flow cytometry, range from 1.63 to 3.61 pg for diploid and to 6.86 pg when including tetraploid species. Intraspecific genome size polymorphism was observed among populations of five out of nine studied species: C. dalmatica, C. ragusina, C. rupestris, C. spinosociliata and C. salonitana. The genome of a tetraploid C. salonitana population was nearly twice that of the diploids. Dysploidy (changement of basic chromosome number) and polyploidy are observed as the main evolutionary mechanisms among studied representatives of the genus Centaurea in Croatia.

XXI. HRVATSKI SKUP …, 2009

Pregled bibliografske jedinice broj: 407184. Zbornik radova. Autori: Mila JUKIĆ, Franko BURČUL, O... more Pregled bibliografske jedinice broj: 407184. Zbornik radova. Autori: Mila JUKIĆ, Franko BURČUL, Olivera POLITEO, Mladen MILOŠ. Naslov: PROCJENA ANTIOKSIDACIJSKE AKTIVNOSTI KARAKTERISTIČNOG MEDITERANSKOG ...

6th Croatian Congres of …, 2010

Abstract: Dalmatian black pine (Pinus nigra Arnold subsp. dalmatica (Vis.) Franco) is a native an... more Abstract: Dalmatian black pine (Pinus nigra Arnold subsp. dalmatica (Vis.) Franco) is a native and endemic tree distributed particularly in the coastal regions of Croatia. The Dalmatian black pine is evergreen conifer species belonging to the family Pinaceae. Most ...

Congress of the Croatian Society of …, 2008

Sažetak: Acetylcholine (ACh) is one of the most important neurotransmitters in animal systems. In... more Sažetak: Acetylcholine (ACh) is one of the most important neurotransmitters in animal systems. Increasing the levels of acetylcholine by inhibition of acetylcholinesterase (AChE), the enzyme responsible for its hydrolysis at the cholinergic synapses, serves as a strategy ...

5th Croatian congress of …, 2007

Pregled bibliografske jedinice broj: 307605. Zbornik radova. Autori: Jukić, Mila; Miloš, Mladen; ... more Pregled bibliografske jedinice broj: 307605. Zbornik radova. Autori: Jukić, Mila; Miloš, Mladen; Politeo, Olivera; Ivanković, Siniša; Stojković, Ranko; Jurin, Mislav. Naslov: In vitro and in vivo antitumor activity of thymoquinone and thymohydroquinone. ...

Chemistry & Biodiversity, 2020

Journal of Medicinal Plants Research, Mar 10, 2019

Edraianthus pumilio is stenoendemic plant native to Dalmatia, Croatia. This paper deals with its ... more Edraianthus pumilio is stenoendemic plant native to Dalmatia, Croatia. This paper deals with its phytochemical and biological profile. Phytochemical profile of volatile oil was performed by the gas chromatography-mass spectrometry (GC/MS), while total phenolic content of its aqueous extract was performed by Folin-Ciocalteu method. The phytochemical analysis showed that the main volatile oil compounds were nonanal (21.2%) and myristicin (16.4%). This oil could be characterized as nonanalmyristicin type. Total phenolic content of aqueous extract was 30.6 ± 1.1 mg GAE/g extract. Results of testing antioxidant potential of E. pumilio volatile oil and aqueous extract showed low antioxidant potentials as tested by 2,2-diphenyl-1-picrylhydrazyl (DPPH) and ferric reducing antioxidant power (FRAP) methods. Results also showed low acetylcholinesterase inhibition potential of volatile oil and low to moderate potential of aqueous extract, as tested by Ellman method.

Antioxidants, 2022

A single phenolic group and even a compound play different roles in the sensory properties and st... more A single phenolic group and even a compound play different roles in the sensory properties and stability of virgin olive oil (VOO), which in turn are strongly influenced by several factors. Understanding the causes of differences in phenolic compound composition and oxidative stability (OS) in VOOs is essential for targeted and timely harvest and processing while maintaining desired oil quality. The phenolic profile and OS of two monocultivar VOOs (Oblica and Leccino) grown in two geographical sites of different altitudes (coastal plain and hilly hinterland) were analyzed throughout the ripening period over two years. Concentration of secoiridoids was 30% higher in the Oblica than in the Leccino VOOs, which in turn had significantly higher values of OS. Both cultivars had more than twice as high concentrations of the two most abundant phenolic compounds, the dialdehyde form of decarboxymethyl oleuropein aglycone and the dialdehyde form of decarboxymethyl ligstroside aglycone, and OS...

U usporedbi s zemljama Centralne i Zapadne Europe, tradicionalna medicina Bosne i Hercegovine je ... more U usporedbi s zemljama Centralne i Zapadne Europe, tradicionalna medicina Bosne i Hercegovine je vecinom neistražena. Jedna od karakteristicnih i nedovoljno istraženih ljekovitih biljnih vrsta je i endemska Satureja subspicata L. (Lamiaceae), koja se na podrucju BiH tradicionalno koristi u lijecenju razlicitih bolesti. Alzheimerova bolest je degenerativna bolest mozga i najcesci oblik demencije koji pogađa stariju populaciju.[1] Brojna oksidativna ostecenja organizma povezuju se s patogenezom ove bolesti. U njenom tretmanu koriste se inhibitori acetilkolinesteraze, enzima koji katalizira hidrolizu acetilkolina, neurotransmitora u mozgu. U potrazi za potencijalnim inhibitorima ovog enzima, brojne samonikle biljke i njihovi sekundarni metaboliti bivaju predmet proucavanja. Cilj ovog rada je bio istražiti kemijski sastav etericnog ulja biljke Satureja subspicata L. te ispitati bioloski potencijal izoliranih hlapljivih spojeva u smislu antioksidacijskog i antikolinesteraznog potencijala...