Olusegun Adesola Busari - Academia.edu (original) (raw)

Papers by Olusegun Adesola Busari

Clinical Medicine Research, 2018

The objective of the study was to determine the prevalence of Hyperuricemia and evaluate its corr... more The objective of the study was to determine the prevalence of Hyperuricemia and evaluate its correlation with target organ damage and electrocardiographic changes in newly diagnosed adult Nigerian hypertensive patients. It was a cross sectional study done at the University of Ilorin Teaching Hospital, Ilorin, Nigeria. 150 untreated newly diagnosed hypertensive patients 18 years and above and 115 age and sex-matched normotensive individuals were recruited into the study. Data obtained was analyzed using Epi-Info version 6.04 and Statistical Package for Social Sciences (SPSS) version 14 computer software packages. The prevalence of Hyperuricemia was 36.7% and 17.4% in hypertensive patients and normotensive controls respectively. Mean serum UA in hypertensive patients and normotensive controls was 0.4±0.1mmol/l and 0.3±0.1mmol/l respectively (p<0.0001). There was an association between Hyperuricemia and left ventricular hypertrophy (x 2 =23.97, p<0.0001). The study showed that Hyperuricemia is prevalent in adult Nigerians with newly diagnosed hypertension. Hyperuricemia was associated with left ventricular hypertrophy which is common target organ damage and confers an increased risk of cardiovascular events in systemic hypertension.

Journal of Public Health in Africa, 2016

Breast cancer is the most common female malignancy linked with high levels of morbidity and morta... more Breast cancer is the most common female malignancy linked with high levels of morbidity and mortality in developing countries due to delayed diagnosis. This research assessed the knowledge of signs and risk factors of breast cancer and practice of self breast examination (SBE) among female nurses in a rural tertiary Hospital. Eighty-five nurses ages 20 to 60 years were sampled by simple randomization over a period of eight weeks through a self-administered semi-structured questionnaire. The analysis was done using statistical package for social science version 17. Sixteen (15.3%) nurses had adequate knowledge of breast cancer, having a relative with breast cancer (51.8%) and a woman of any age (56.5%) were recognized by majority as risk factors for breast cancer. Majority (68.2%) were not practicing monthly SBE and not confident on how to do it. This study pointed out the gaps in the knowledge and awareness of breast cancer and practice of SBE among the nurses. Opportunity should therefore be sought in various health facilities to educate nurses who are supposed to be closer to the patients.

Journal of contemporary medicine, Sep 1, 2013

Hipertansiyon, tüm dünyada toplum sağlığı önemi olan yaygın bir hastalıktır. Amaç kaynak kısıtlı ... more Hipertansiyon, tüm dünyada toplum sağlığı önemi olan yaygın bir hastalıktır. Amaç kaynak kısıtlı ortamda, üçüncü basamak hastanede sistemik hipertansiyonu olan erişkinlerde aritmi prevelansı, paternleri ve ilişkili faktörleri belirlemektir. Materyal ve metod: Nijerya, Ido-Ekiti'de Federal Tıp Merkezinin Kardiyloji ünitesine hipertansiyon ile başvuran 18 yaş ve üzeri erişkin hastalarda 12 derivasyonlu istirahat elektrokrdiyogramını kapsayan kesitsel bir araştıradır. Sonuçlar: Altıyüziki (602) erişkin Nijeryalının istirahat elektrokardiyogramı çalışıldı. 340'ı erkek (%56.5) ve 262'i (%43.5) kadındı. Hastalaron ortalama yaşları 58.3±10.7 yıldı. Doksansekiz hastada (%16.3) aritmi mevcuttu. Aritmisi olmayanlar ile karşılaştırıldığında, aritmisi olan hastalar daha yaşlıydı (62.3±12.8 vs. 56.1±13.2, p =0.03), QTc uzaması (14.3% vs. 6.0%, p = 0.041), sol ventriküler hipertrofisi (24.5% vs 12.7%, p = 0.026) prevelansı daha yüksekti ve kalp yetmezliğinde olmaya yatkındı (32.7% vs. 8.5%, p < 0.001). Tartışma: Bu araştırma hipertansiyonu olan erişkin Nijeryalılardaaritmi prevelansının %16.3 olduğunu göstermiştir. Erken ventriküler kompleks ve atrial fibrilasyon en sık aritmilerdir. Daha yaşlı olma, yüksek sistolik ve diastolik kan basıncı ve sol ventriküler hipertrofi ve QTc uzaması aritmi ile ilişkilidir.

Transplantation Direct, 2016

The global increase in end organ failure but disproportional shortage of organ donation calls for... more The global increase in end organ failure but disproportional shortage of organ donation calls for attention. Expanding the organ pool by assessing and improving health workers' attitude at all levels of care may be a worthwhile initiative. Methods. A questionnaire-based cross sectional study involving tertiary, secondary, and primary health institutions in Southwestern Nigeria was conducted. Results. Age range was 18 to 62 (36.7 ± 9.2) years. Only 13.5%, 11.7%, and 11.2% from primary, secondary, and tertiary health centers, respectively, would definitely donate despite high level of awareness (>90%) at each level of care. Participants from primary health care are of low income (P < 0.05), and this cohort is less likely to be aware of organ donation (P < 0.05). At each level of care, permission by religion to donate organs influenced positive attitudes (willingness to donate, readiness to counsel families of potential donors, and signing of organ donation cards) toward organ donation. Good knowledge of organ donation only significantly influenced readiness to counsel donors (P < 0.05) and not willingness to donate (P > 0.05). At each level of health care, young health care workers (P < 0.05) and women (P > 0.05) would be willing to donate, whereas men show positive attitude in signing of organ donor cards (P < 0.05) and counseling of families of potential donors (P > 0.05). Conclusions. Knowledge and willingness to donate organs among health care levels were not different. Considering the potential advantage of community placement of other tiers of health care (primary and secondary) in Nigeria, integrating them would be strategically beneficial to organ donation.

American Journal of Health Research, 2015

Background: Immunisation is a cost effective public health intervention in reducing morbidity and... more Background: Immunisation is a cost effective public health intervention in reducing morbidity and mortality from vaccine preventable diseases worldwide. In Nigeria, childhood immunisation against poliomyelitis is still bedeviled by setbacks which are multifactorial. Objectives: The objective of the study was to determine the knowledge, attitude and perceptions of adult males towards childhood immunizations in Nigeria. Methods: The research was a descriptive crosssectional study of adult males in the Ido-Osi local government area of Ekiti state, southwest Nigeria. Multistage sampling method was used to select 320 adult males for the study, and a pre-tested semi-structured questionnaire was used to collect quantitative data. Statistical analysis was done using the Epi Info 4. P value <0.05 was considered as statistically significant. Results: Mean age (±SD) of the respondents was 48.4±12.6 years with range of 20-95 years. About half (50.6%) of the respondents were in the age group 40-59 years. 79.7% were married while only 2 were single with about two-thirds of the married respondents in monogamous family type. 82.3% were willing to support childhood immunization. The association between respondents' religion and education, and willingness to support childhood immunization was found to be statistically significant: (x 2 =51.53; df=6; p=0.0000) and (x 2 =65.48; df=6; p=0.0000) respectively. Conclusion: The study showed that the knowledge of adult males about childhood immunization was high. The perception of childhood immunization as a means of protection from certain illnesses was also common and most men were willing to support it. The support for childhood immunization was significantly affected by religion and level of education.

Ghana Medical Journal, 2011

Sultan Qaboos University Medical Journal, 2013

TAF Preventive Medicine Bulletin, 2012

ÖZET GİRİŞ: HIV pozitif hastaların aile fertleri için HIV testi, eşlerin durumunun anlaşılmasını,... more ÖZET GİRİŞ: HIV pozitif hastaların aile fertleri için HIV testi, eşlerin durumunun anlaşılmasını, ailevi sosyal desteğin teşvik edilmesini ve HIV hizmetlerine erişimin artırılmasını sağlayabilir. Amaç, Batı Nijerya'da HIV tedavisi için belirlenen federal bir hastanede yatan hem HIV pozitif ve negatif hastaların aile üyeleri arasında HIV yaygınlığının belirlenmesi için rutin HIV testi yaklaşımının kullanılmasıdır. YÖNTEM: Bu prospektif çalışma, Ocak 2006 ile Haziran 2009 tarihleri arasında gerçekleştirilmiştir. Etik izni çalışma öncesinde hastane araştirma ve etik komitesinden alınmıştır. Her katılımcıdan aydınlatılmış onam alınmıştır. HIV testi, HIV pozitif ve negatif hastaların çalışmaya katılmayı kabul etmiş aile üyelerine yapılmıştır. Aile üyelerinden kasıt; eşler, hastaların çocukların, çocuk hastaların ebevyni ve diğer aile bireyleridir. Analiz olarak frekans ve yüzdelik yapılmıştır. BULGULAR: 184 hasta ile 162 aile üyesi teste sokulmuştur. Aile üyelerinin dağılımı eşler 81 (%50,0), babalar 14 (%8,6), anneler 20 (%12,3), çocuklar 19 (%11,7) ve diğer aile üyeleri 28 (%17,3) kişi şeklindedir. 151 (%93,2) kişi teste ilk kez katılmıştır. Test edilen kişilerin çoğunluğu (%82,1) test sonrası danışmanlık almıştır. Genel olarak HIV yaygınlığı %12,3 (20/162) idi. Farklı aile bireyleri içinde HIV prevalansı eşlerde %14,8 (12/81), annelerde %20 (4/20), babalarda %7,1 (1/14), çocuklarda %10,5 (2/19) ve diğer aile üyeleri %3,6 (1/28) şeklindedir. HIV pozitif ve negatif bireylerin aile üyelerinde HIV prevalansı sırasıyla %15,6 (14/90) ve %8,3 (6/72) idi. 12 eş pozitif, 7 (%13,5) eş HIV-uyumsuz bulunmuştur ve HIVuyumsuz çiftlerin %71,4 (5/7) inde hasta negatif iken eş pozitifdir. SONUÇ: Sonuçlar, hastaların aile üyelerine rutin HIV testi yapılamasının, çok sayıda HIV enfekte kişinin belirlenmesi için bir strateji olduğunu göstermektedir. Bu yöntem sadece yenilikçi değil ayrıca, HIV önleme, Nijerya ve Sahra-altı Afrika'nın geri kalanında bakım ve tedavi hizmetlerine erişimi arttırmak için yeni bir yaklaşımdır. SUMMARY AIM: HIV testing for family members of HIV-positive patients may enhance disclosure of status of spouses, encourage family social support and improve access to HIV services. Objective was to employ the approach of routine HIV testing to determine the prevalence of HIV among family members of both HIV positive and negative patients on admission in a federal HIV treatment designated hospital in Western Nigeria METHOD: This prospective study was conducted between January 2006 and June 2009. Ethical clearance was obtained from the Research and Ethics committee of the hospital prior to the study. Informed consent was obtained from each participant. HIV testing was offered to consenting family members of HIV positive and negative patients on admission. The family members included spouses, children of patients, parents of paediatric patients and other family members. Analysis was done in frequencies and percentages. RESULTS: 162 family members of 184 patients were tested. Spouses were, 81 (50.0%); fathers, 14 (8.6%); mothers, 20 (12.3%); children, 19 (11.7%) and others family members, 28 (17.3%). 151 (93.2%) of testers were first timers. Majority of those tested (82.1%) had post-test counseling. The overall HIV prevalence was 12.3% (20/162). HIV prevalence within different family members was 14.8% (12/81), 20% (4/20), 7.1% (1/14), 10.5% (2/19) and 3.6% (1/28) for spouses, mothers, fathers, children and others respectively. In addition, the prevalence of HIV among family members of HIV positive and negative patients was 15.6% (14/90) and 8.3% (6/72) respectively. Of 12 spouses that were positive, 7 (13.5%) were HIV-discordant; and in 71.4% (5/7) of discordant couples, the spouse was positive while the patient on admission was negative. CONCLUSION: The results indicate that routine HIV testing of family members of patients on admission is a strategy for identification of vast number of HIV infected persons. This method is not only innovative, but also a novel approach for scaling up of access to HIV prevention, care and treatment services in Nigeria and the rest of sub-Sahara Africa

Pan African Medical Journal, 2011

BMC Pulmonary Medicine, 2009

Background: Spirometry is a cost-effective diagnostic tool for evaluation of lung function and fo... more Background: Spirometry is a cost-effective diagnostic tool for evaluation of lung function and for case-finding in a resource-limited setting. The acceptance of this test depends on the awareness of its indications and the ability to interpret the results. No studies have assessed the knowledge of spirometry among Nigerian doctors. The aim of this study was to evaluate the current knowledge, awareness and practice of spirometry among hospital-based Nigerian doctors. Methods: We carried out a cross-sectional survey among 321 doctors working in Nigerian hospitals between March 2008 and June 2008. Information on knowledge, awareness, practice of and barriers to spirometry were obtained using a pre-tested, self-administered structured questionnaire and the data were then analysed. Results: Of the 321 doctors that participated, 108 (33.6%) reported that they have good knowledge of spirometry. One hundred and ninety-five (60.7%) were aware of the importance of spirometry in aiding the diagnosis of respiratory diseases; 213(66.4%) were aware of the importance of spirometry in determining the severity of diseases. Medical school was the most common source of knowledge on spirometry (64.5%). Eighty-one (25.2%) doctors reported having a spirometer in their hospitals. Doctors having access to a spirometer used it more frequently for aiding the diagnosis of COPD (40.7% vs.27.5%) and for monitoring of asthma (18.5% vs.11.3%) than those without access to a spirometer. The doctors working in University Teaching Hospitals and Federal Medical Centres (FMC) (22.4% vs. 4.5%) and those having access to a spirometer (40.7 vs.11.3%) were very confident of interpreting spirometry results compared to those working in District and General Hospitals and without access to a spirometer. Irrespective of access to a spirometer or the type of hospital they were employed in, doctors reported that unavailability of a spirometer was the greatest barrier to its use (62.5%) followed by lack of awareness about its usefulness (17.2%). Conclusion: The knowledge and practice of spirometry were poor among hospital-based Nigerian doctors because of unavailability of spirometers in most hospitals. These findings have implications for further evaluation, planning and management of patient care in respiratory disease. Spirometers should be made available in all hospitals, and the knowledge of spirometry should be improved among doctors.

Annals of African Medicine, 2011

Cardiology journal, 2010

Microalbuminuria (MA) is a predictor of excess cardiovascular morbidity and mortality in non-diab... more Microalbuminuria (MA) is a predictor of excess cardiovascular morbidity and mortality in non-diabetic hypertensive patients. This study evaluated the electrocardiographic correlates of MA in adult non-diabetic Nigerians with essential hypertension. Ninety-six newly diagnosed hypertensive patients who consented and met the inclusion criteria for the study were recruited. Ninety-six age- and gender-matched normotensive controls were also studied. Resting 12-lead electrocardiogram of all patients and controls was done and the tracings analyzed by the authors for left ventricular hypertrophy with or without repolarization abnormalities, QTc prolongation, conduction abnormalities and cardiac arrhythmias such as atrial fibrillation. MA was present in 31 (32.3%) of the hypertensive patients and in only six (6.25%) of the normotensive controls. Electrocardiographic left ventricular hypertrophy (ECG LVH) was significantly more commonly found in patients with MA than in patients without it (7...

Nigerian Journal of Clinical Practice, 2011

Objective: Microalbuminuria (MA) is a marker of vascular damage and has prognostic implications i... more Objective: Microalbuminuria (MA) is a marker of vascular damage and has prognostic implications in hypertension. The objective of this study was to determine if the presence of MA increases the risk of hypertensive retinal damage in nondiabetic adult Nigerians with hypertension. Materials and Methods: A total of 96 consecutive newly diagnosed hypertensive patients attending the outpatient clinic and who consented and met the criteria for the study were recruited. There was also the same number of age-and sex-matched normotensive controls. Results: MA was present in 31 (32.3%) of the patients and 6 (6.3%) of the controls. The mean (±SD) ages of patients with and without MA were 52.5 ± 11.9 years and 48.3 ± 13.0 years, respectively. The diastolic blood pressure (P = 0.03) and mean arterial pressure (P = 0.01) were statistically higher in hypertensive patients with MA than in their counterparts without it. Patients with MA were more likely to have hypertensive retinopathy (HRP) than patients without it (71% vs 37%, P = 0.001). Advanced HRP, i.e., Grades III-IV, was more common in patients with MA than in those without it (22.6% vs 1.5%). Conclusion: This study shows a high prevalence of HRP in Nigerian hypertensives with MA.