Omer Shoaib - Academia.edu (original) (raw)

Papers by Omer Shoaib

i-manager's journal on computer science, 2020

International Journal of Research in Medical Sciences, 2016

International Journal of Medical Science and Public Health, 2015

Context: Diabetes mellitusis one of the most diseases of life threading through its completing co... more Context: Diabetes mellitusis one of the most diseases of life threading through its completing complexes such as dyslipidemia is one of the major risk factors for cardiovascular disease and metabolic disorders in diabetes mellitus. Aims: The primary objective of our study was to evaluate and assess the control of dyslipidemia in diabetes mellitus. The importance of the study was that the lipids disorders affect approximately 14% of patients with diabetes mellitus whereas in non-diabetics the prevalence is approximately 6%. Settings and Design: A casecontrol and hospitalbased analytical study was conducted from January 2016 to November 2017 in Khartoum state. Methods: Two hundred Sudanese adult with T2DM were selected as test group and 100 apparently healthy volunteers as controls both groups were age and sex matched. Venus blood samples were after overnight fasting from all participants, the following parameters were surveyed: Total cholesterol (T.CH), Triglycerides (TG), High densi...

Background: Stein-Leventhal syndrome, also called polycystic ovarian syndrome (PCOS) is the most ... more Background: Stein-Leventhal syndrome, also called polycystic ovarian syndrome (PCOS) is the most common endocrinopathy that affects women.Has been one of a major public health problem in Sudan that leads to medical consequences. It causes multifactorial in etiology such as menstrual dysfunction, hyperandrogenism, hirsutism, insulin resistance (IR), dyslipidemia and obesity which increased risk of diabetes mellitus and cardiovascular disease. We know that if patients with PCOS are screened for these diseases, many long-term complications can be prevented. Objective: The present study was designed to assess serum gonadotropin hromones [luteinizing hormone (LH), Follicle stimulating hormone (FSH)] and insulin in PCOS Sudanese women and to compare them with healthy women as controls. Materials and Methods: This study was a descriptive, analytic, crosssectional and hospital-based study, included Sudanese women with PCOS live in KhartoumStateSudan, in period from March 2013 to May 2014. A...

Autoimmune thyroiditis (AIT) in type 1 Diabetes Mellitus (T1DM) was studied in many cases, but th... more Autoimmune thyroiditis (AIT) in type 1 Diabetes Mellitus (T1DM) was studied in many cases, but the association between duration of type1 DM and autoimmune thyroiditis not well clarified. However, very limited data are available from Saudi Arabia, despite an increase in the incidence of disease. This study aimed to find out the possible association between diabetes duration and thyroid antibodies; antiThyroid Peroxidase (anti-TPO) & antiThyroglobulin (antiTG) and anti-glutamic acid decarboxylase (anti-GAD) in Saudi children with type 1DM. The study included 132 diabetics children selected from Najran area According to the duration of diabetes grouped into group 1: less than 2 years, group 2: 2 up to 5 years, group 3: 6 up to 10 years and group 4: more than 10 years. Blood levels of antiTPO, anti-TG and antiGAD antibodies were determined by ELISA and TSH using ELC whileHbA1c was measured using chromatography technique. The highest serum GAD antibodies values were for group 1 (diabetic...

Sickle cell disease (SCD) is a group of haemoglobin disorders that increase the rate of morbidity... more Sickle cell disease (SCD) is a group of haemoglobin disorders that increase the rate of morbidity and mortality. Blood transfusions have reduced morbidity and mortality for patients with SCD, but it can lead to erythrocyte alloimmunization the main aim in this descriptive analytical study, we determine the frequency of Rh antigens (C, D, c, E, and e) among sickle cell patients as well as to determine the frequency of kell1 antigen which will be useful in blood transfusion. The study was conducted during approximately eight months, followed informed consent, a total of 160 venous blood samples were collected from sickle cell patients in to 2.5 ml EDTA containers .All samples were tested for Rh D antigen using the slide agglutination techniques, and the same samples tested for Rh C, c, E, e, and kell1 antigens by immunodifusion gel technique. The results obtained showed that, the c antigen was most common frequency (100%), followed by D antigen occurred (90%), e antigen was found to b...

In view of the increasing number of patients with polycystic ovary syndrome (PCOS) among Sudanese... more In view of the increasing number of patients with polycystic ovary syndrome (PCOS) among Sudanese women, and its impact in infertility and other complications, this study was conducted to determine and to evaluate insulin and glucose profiles changes that may help and facilitate the diagnosis and flow up of this disease. Objectives: The aim of this study was to investigate the concentration and potential role of insulin and glucose levels in Sudanese women with PCOS. Materials and Methods: descriptive, analytic, crosssectional and hospital-based study included Sudanese women from KhartoumStateSudan, in period from March 2012 to May 2014. A total of 200 Sudanese women with PCOS were compared with 100 women without PCOS as control group, all of them were age-and weight-matched, Samples were taken after overnight fasting then plasma insulin and glucose levels were analyzed using ELISA technique and colorimetric methods. Results: The (mean ± SD) plasma insulin and glucose in women with ...

Context: Diabetes Mellitus, the most common non-communicable disease and the diseases of thyroid ... more Context: Diabetes Mellitus, the most common non-communicable disease and the diseases of thyroid gland are amongst the most abundant endocrine disorders in the world second only to diabetes. The study problem was that the modes of association between DM and thyroid diseases are more complex and unclear. Aims: This study was carried out to evaluate the associations between type 1 diabetes mellitus and thyroid dysfunction. The importance of the study was that the thyroid diseases affect approximately 10-15% of patients with diabetes mellitus whereas in non-diabetics, the prevalence is approximately 6%. Settings and Design: A casecontrol and hospitalbased analytical study was conducted from January 2015 to November 2016. Methods: Two hundred and five Sudanese patients with T1DM were selected as test group 100 apparently healthy volunteers as controls both groups were age and sex matched. In all participants, the following antibodies were surveyed: Anti‐glutamic acid decarboxylase (anti...

Polycystic ovarian syndrome (PCOS) is the most common endocrinopathy that affects women. It has b... more Polycystic ovarian syndrome (PCOS) is the most common endocrinopathy that affects women. It has been one of a major public health problem in Sudan that leads to medical consequences, it causes multifactorial in etiology such as menstrual dysfunction, hyperandrogenism, hirsutism, insulin resistance (IR), dyslipidemia and obesity which increased risk of diabetes mellitus and cardiovascular disease.Itknow that if patients with PCOS are screened for these diseases, many long-term complications can be prevented. Objective: The present study was designed to assess serum luteinizing hormone andinsulin in PCOS Sudanese women and to compare them with healthy women as controls. Materials and Methods: This study was a descriptive, analytic, crosssectional and hospital-based study, carried in KhartoumStateSudan; it was carried out in March 2013 to May 2014. 200 women with PCOS were enrolled in this study, they compared with 100 healthy women as control group, all of them were age-and weight-mat...

Polycystic ovarian syndrome (PCOS) has been one of a major public health problem in Sudan that le... more Polycystic ovarian syndrome (PCOS) has been one of a major public health problem in Sudan that leads to medical consequences. It causes multifactorial in etiology such as menstrual dysfunction, hyperandrogenism, hirsutism, dyslipidemia and obesity which increased risk of diabetes mellitus and cardiovascular disease. Objective: The aim of this study was to investigate the concentration and potential role of insulin and lipid levels in Sudanese women with PCOS. Materials and Methods: This study was a descriptive, analytic, crosssectional and hospital-based study, carried in KhartoumStateSudan; it was carried out in March 2013 to May 2014. 200 women with PCOS were enrolled in this study, they compared with 100 healthy women as control group, all of them were age-and weight-matched, Samples were taken after overnight fasting then serum insulin and lipid levels were analyzed using ELISA technique and enzymatic colorimetric methods. Data management and analysis was done by using Microsoft...

International Journal of Science and Research (IJSR), 2015

International Journal of Medical Science and Public Health, 2015

Diagnostic Molecular Pathology, 2000

Early diagnosis of tuberculosis (TB) is important for early medical intervention and prevention o... more Early diagnosis of tuberculosis (TB) is important for early medical intervention and prevention of spread of the bacteria. It is not uncommon to observe granulomatous inflammation but without demonstrable acid-fast bacilli (AFB) on Ziehl-Neelsen (ZN) staining in tissues sent for histologic examination, and the definitive diagnosis of TB cannot be made because no concurrent tissue is sent for TB culture. In this study, the authors explored the feasibility of using polymerase chain reaction (PCR) for early detection of Mycobacterium tuberculosis (Mtb) in formalin-fixed, paraffin-embedded tissues where a definite diagnosis of TB cannot be made. One hundred fifteen patients (131 paraffin blocks of biopsy specimens) with granulomatous inflammation but ZN-negative for AFB were studied. DNA was extracted from paraffin sections and amplified by PCR with the IS6110 primers (specific for the Mtb complex) and the specific 122-base pairs (bp) PCR product was detected by agarose gel electrophoresis. Sixty-eight of the 115 (59%) patients were TB-PCR positive, thus enabling definite diagnosis of TB in significant numbers of these patients in 3 days. The authors conclude that molecular diagnosis by PCR is useful for early detection of TB in histologic material where morphologic features are suggestive but not confirmatory because of negative staining for AFB.

As obesity is rapidly becoming a major medical issue, it’s associated with many cardiovascular ri... more As obesity is rapidly becoming a major medical issue, it’s associated with many cardiovascular risk factors and others public health problem, the aim of our present study is to investigate the concentration and evaluate potential role of insulin and lipids profile, total cholesterol (TC), Triglyceride (Trig), high density lipoprotein-cholesterol (HDL-C), low density lipoproteincholesterol (LDL-C) levels and insulin among obese Sudanese women. A prospective analytic, crosssectional and hospital-based study included Sudanese women from KhartoumStateSudan, in period from March 2012 to May 2014. A total of 200 obese Sudanese women were compared with 100 healthy non obese women as control group, all of them were age-matched, Samples were taken after overnight fasting then serum insulin and lipids were analyzed using ELISA technique and colorimetric methods. The (mean ± SD) of serum insulin and (TC, Trig, HDL-C and LDL-C) in obese women were 11.06±6.21μIU/ml,166.95±46.94mg/dl, 89.89±33.36...

i-manager's journal on computer science, 2020

International Journal of Research in Medical Sciences, 2016

International Journal of Medical Science and Public Health, 2015

International Journal of Science and Research (IJSR), 2015

International Journal of Medical Science and Public Health, 2015

Diagnostic Molecular Pathology, 2000