Omolola Atalabi - Academia.edu (original) (raw)

Papers by Omolola Atalabi

European Journal of Radiology, 2012

Background: Magnetic resonance imaging (MRI), an advancement which followed computed tomography (... more Background: Magnetic resonance imaging (MRI), an advancement which followed computed tomography (CT) is expensive and inaccessible in most developing countries. However it is the procedure of choice in evaluating sellar and parasellar lesions. Its major advantages are its superior soft tissue contrast differentiation, its capacity for multiplanar imaging and nonexistence of ionising radiation. Its use is relatively new in Nigeria, a developing economy in Africa. Since its introduction in 2005, it has been utilised extensively for neuroimaging at the University College Hospital (UCH), Ibadan; a large hospital in south-western Nigeria. Objective: To review the role and pattern of low field MR Imaging in sellar and parasellar lesions presenting to a tertiary care centre in Nigeria. Methods: All 62 patients with clinically suspected sellar and parasellar masses, referred to the Department of Radiology, UCH Ibadan for MRI between December 2006 and January 2010 were retrospectively analysed. The examinations were performed using an open 0.2 T permanent magnet MR unit. T1W, T2W, T2/FLAIR, TOF and T1W post gadolinium DTPA sequences of the sellar region were obtained. Results: Of the 62 patients, there were 27 males and 35 females. The modal age group was 40-49 years with a mean age of 39.94 years (±16.65 years). Twenty-four cases (38.7%) had histological diagnosis, of which 20 (83.3%) were consistent with initial MRI diagnosis. Pituitary adenomas were the commonest (58.06%) lesions of the sellar and parasellar regions. Others include parasellar meningiomas, cranipharyngiomas, and giant aneurysms. Headache and visual impairment were the major presenting features and showed no significant correlation with tumour size. Conclusion: The use of low field MRI in the diagnostic evaluation of patients with suspected sellar or parasellar lesions in developing countries of low economic resource is commendable as it provides beneficial outcomes in management.

Tropical Journal of Obstetrics and Gynaecology, 2013

Nigerian journal of physiological sciences : official publication of the Physiological Society of Nigeria, Jan 20, 2015

The resistive and pulsatility indices are known tools for assessing renal function in kidney dise... more The resistive and pulsatility indices are known tools for assessing renal function in kidney diseases, especially in proteinuric conditions like Paediatric Nephrotic syndrome (NS) which is a glomerular disease. However, there is a limited knowledge in the use of Doppler Resistive and pulsatility indices in the management of this disease condition. This was a case control study involving 53 cases and 57 controls. The Doppler parameters, resistive index (RI) and pulsatility index (PI) of the renal interlobar arteries were determined for the upper, middle, and lower poles bilaterally for both controls and cases. The mean RI on the right and left were 0.59 ± 0.06 and 0.58 ± 0.06 respectively for the NS cases whereas for the controls it was 0.61 ± 0.05 and 0.60 ± 0.04 on the right and left respectively. The mean PI on the right and left measured 0.96 ± 0.16 and 0.94 ± 0.15 respectively for the NS cases while that for the control cases measured 0.98 ± 0.13.and 0.95 ± 0.12 on the right and...

Pediatric Radiology, 2009

Congenital diaphragmatic hernias are complex and life-threatening lesions that are not just anato... more Congenital diaphragmatic hernias are complex and life-threatening lesions that are not just anatomic defects of the diaphragm, but represent a complex set of physiologic derangements of the lung, the pulmonary vasculature, and related structures. Imaging plays an increasingly important role in the care of these infants. Prenatal sonography and MRI have allowed early and accurate identification of the defect and associated anomalies. These tools have also been the key to defining the degree of pulmonary hypoplasia and to predicting neonatal survival and need for aggressive respiratory rescue strategies. In the postnatal period, conventional radiography supplemented by cross-sectional imaging in selected cases can be very useful in sorting out the differential diagnosis of intrathoracic masses, in the detection of associated anomalies, and in the management of complications. Understanding the pathogenesis of diaphragmatic defects, the underlying physiologic disturbances, and the strengths and limitations of current imaging protocols is essential to the effective and accurate management of these complex patients.

Skeletal Radiology, Jul 16, 2008

We report here the imaging findings of a rare case of a lethal form of Gorham disease in a young ... more We report here the imaging findings of a rare case of a lethal form of Gorham disease in a young female patient. Multimodality imaging findings over 13 yearfollow-up demonstrated progressive wide spread skeletal and soft tissue abnormalities with permeative osteolysis, pathological fractures and severe skeletal deformities. Unusual extensive osseous and soft tissue pneumatosis was illustrated on cross-sectional studies. The progressive nature of this form of Gorham disease and the subsequent complications eventually culminated in patient's death.

Pan African Medical Journal, 2015

Electroencephalography (EEG) remains the most important investigative modality in the diagnostic ... more Electroencephalography (EEG) remains the most important investigative modality in the diagnostic evaluation of individuals with epilepsy. Children living with epilepsy in the developing world are faced with challenges of lack of access to appropriate diagnostic evaluation and a high risk of misdiagnosis and inappropriate therapy. We appraised EEG studies in a cohort of Nigerian children with epilepsy seen in a tertiary center in order to evaluate access to and the impact of EEG in the diagnostic evaluation of the cases. Inter-ictal EEG was requested in all cases of pediatric epilepsy seen at the pediatric neurology clinic of the University College Hospital, Ibadan, Nigeria over a period of 18 months. Clinical diagnosis without EEG evaluation was compared with the final diagnosis post- EEG evaluation. A total of 329 EEGs were recorded in 329 children, aged 3 months to 16 years, median 61.0 months. Clinical evaluation pre-EEG classified 69.3% of the epilepsies as generalized. The a posteriori EEG evaluations showed a considerably higher proportion of localization-related epilepsies (33.6%). The final evaluation post EEG showed a 21% reduction in the proportion of cases labeled as generalized epilepsy and a 55% increase in cases of localization-related epilepsy(p&amp;amp;amp;lt;0.001). Here we show that there is a high risk of misdiagnosis and therefore the use of inappropriate therapies in children with epilepsy in the absence of EEG evaluation. The implications of our findings in the resource-poor country scenario are key for reducing the burden of care and cost of epilepsy treatment on both the caregivers and the already overloaded tertiary care services.

West African Journal of Radiology, 2013

African journal of medicine and medical sciences

ABSTRACT

Journal of the National Medical Association

Hepatocellular carcinoma (HCC) is usually diagnosed at an advanced stage, when little remedy coul... more Hepatocellular carcinoma (HCC) is usually diagnosed at an advanced stage, when little remedy could be offered. There is a need for relatively affordable, available and noninvasive tests for diagnosis, staging and detection of metastasis among individuals at risk. A clinical, chest radiographic (CXR) and abdominal ultrasonographic examination was carried out to detect and evaluate the pattern of metastasis among 53 untreated patients. One patient had clinical paraparesis with no outward evidence of metastasis. CXR revealed lung metastasis in 11 (20.8%), with multifocal deposits and bilateral involvement in 10 (18.8%), and unilateral single deposit in one. Two (3.8%) patients had perihilar lymphadenopathy and consolidation, respectively, while 18 (34%) patients had elevated right hemidiaphragm and four (7.5%) had pleural effusion.

Nigerian journal of medicine: journal of the National Association of Resident Doctors of Nigeria

The metacarpal index (MI) is used in screening for patients with arachnodactyly especially Marfan... more The metacarpal index (MI) is used in screening for patients with arachnodactyly especially Marfan's syndrome. It is a radiographic measure of the slenderness of the 2nd-5th metacarpals, which was measured in a total of 608 Nigerians of which 55 (9%) were children and 553 (91%) were adults. The study shows that the MI increases steadily in children approaching the adult value at about the age of 9 years in females and 13 years in males coinciding with menarche and puberty respectively. A metacarpal index of up to 11 can be considered to be within normal limits for a Nigerian adult. In both children and adults, the MI was found to be higher in females than in males. In both sexes the metacarpal index for the left hand in the adult subjects is generally higher than that of the right hand, but in children, no significant difference is observed. As in other Africans, Nigerian adults have a higher MI than Caucasians.

British Journal of Medicine and Medical Research, 2014

To determine the prevalence of cholelithiasis in Nigerians with sickle cell disease in steady sta... more To determine the prevalence of cholelithiasis in Nigerians with sickle cell disease in steady state, using ultrasonography. Study Design: A prospective cross-sectional study. Place and Duration of Study: Haematology Clinic, University of Benin Teaching Hospital, Benin City and Sickle Cell Centre, Benin City, Nigeria between July and December 2011. Methodology: The study population was made up of non-pregnant sickle cell disease patients not in crisis and who have not had cholecystectomy. They were confirmed to have sickle cell disease through haemoglobin electrophoresis. All the patients were examined with a B-mode ultrasound machine with a curvilinear multifrequency transducer 2.5-7.5MHZ after an overnight or at least six hour fast. Calculi were diagnosed if highly echogenic structures, with acoustic shadowing were detected in the lumen of the gallbladder. Results: There were 79 females and 71 males, aged between 10 months and 51 years. Of the 150 patients, 140 were homozygous for sickle cell disease (HbSS), while the remaining 10 were heterozygous for sickle cell disease (HbSC). The prevalence of

PURPOSE Plasmodium falciparum malaria, a major cause of morbidity in children may affect kidneys ... more PURPOSE Plasmodium falciparum malaria, a major cause of morbidity in children may affect kidneys leading to tubulointerstitial damage and glomerulonephritis. The purpose of this study was to describe the renal ultrasonographic findings associated with acute malaria among Nigerian children. METHOD AND MATERIALS In a case control study, children with microscopically confirmed falciparum malaria infection seen at the University College Hospital, Ibadan over a period of 6months were systematically selected. Children with WHO-defined Severe Malaria (SM, n=16) were cases while Uncomplicated Malaria (UM, n=16) were control group (age-matched).All participants were screened for renal abnormalities at presentation using portable ultrasound units with Doppler facility. Main outcome variables were kidney volume and indices of renal blood flow. Comparisons were made between SM and UM. Level of significance was set at p=0.05. RESULTS Participants were aged 7 to 112 months, mean age of 58.6±31.8 ...

There have been reports of high rate of abnormal bone mineral densities (BMD) among people living... more There have been reports of high rate of abnormal bone mineral densities (BMD) among people living with HIV. Following the introduction of combination antiretroviral therapy (CART) into Nigeria, the country is now home to increasing population of HIV positive patients. There is paucity of data about osteoporosis/osteopaenia and bone mineral density in this population. The aim of the study was to determine the prevalence and determinants of osteopaenia/osteoporosis in a cohort of HIV-positive patients in Nigeria. The BMD of a group of patients attending the outpatient clinic of the University of Ibadan, Nigeria was assessed using a DXA machine. The relationship of bone mineral density to body weight, CART status, protease inhibitor use, and gender was investigated. Their CD4 counts and viral load were also estimated. A total of 1005 patients participated with a mean age of 41.3 ± 10 years. There were 724 females (72.0%) and 29.7% were single. The median length of diagnosis was 2 years...

British Journal of Medicine and Medical Research, 2013

Background: Radiation protection in paediatric radiology requires special attention than in adult... more Background: Radiation protection in paediatric radiology requires special attention than in adult because children are more sensitive to radiation and at higher risk. This risk is explained by the longer life expectancy in children which allows for harmful effects of radiation to manifest and their developing organs and tissues being more sensitive to radiation. Hence, the need for determination of appropriate radiation dose for paediatric patients. Aims: To estimate entrance skin dose (ESD) received by paediatric patients during diagnostic x-ray examinations. Materials and Methods: A total of 253 paediatric patients undergoing various x-ray examinations between June 2011 and December, 2012 in a teaching hospital in the South West Nigeria were considered in this study. This hospital has no dedicated x-ray

African journal of reproductive health, 2014

The aim of this study is to determine if the intensity and nature of pain during Hystero-Salphing... more The aim of this study is to determine if the intensity and nature of pain during Hystero-Salphingography could give a clue to the presence of abnormal finding/s. Eighty-two patients were recruited over a six-month period. Procedural pain was assessed using the numeric rating scale. Mean age was 33.2 +/- 4.9 years. The median pain score in patients with normal findings was 6.0 but 7.0, 8.0, and 8.5 in those with right tubal blockade, uterine fibroids and left tubal blockade respectively. No statistical difference in the absolute pain score between patients with normal and abnormal findings. Pain scores in patients with 1 and 2 abnormalities were 7.0 and 7.5, and the number of abnormalities did not affect pain score (P = 0.3). The presence or absence of pain during HSG may not be a suitable way of determining the presence or absence of abnormal HSG finding/s.

African journal of medicine and medical sciences, 2006

A six weeks old infant presented with scalp ulcer and fever. and on examination was found to have... more A six weeks old infant presented with scalp ulcer and fever. and on examination was found to have resonant percussion notes bilaterally. The initial chest radiograph revealed multiple lucencies which were initially thought to be due to diaphragmatic hernia, but the dilemma was resolved by Computerised tomography which revealed the lucencies to be multiple cysts characteristics of Congenital Cystic Adenomatiod Malformation (CCAM) type II.