Seda Onur - Academia.edu (original) (raw)

Papers by Seda Onur

Nigerian Journal of Clinical Practice

Background: Postoperative bronchopleural fistula (BPF) remains a serious complication due to its ... more Background: Postoperative bronchopleural fistula (BPF) remains a serious complication due to its high morbidity and mortality. Although various endoscopic techniques have been defined for the closure of BPF previously, no standard algorithm yet exists. Aims: To study the effectiveness and safety of various endoscopic procedures in an interventional pulmonology unit. Materials and Methods: The medical data of 15 postoperative BPF patients, who were undergone endoscopic intervention were retrospectively investigated. Results: The mean size of the fistulas determined by bronchoscopic evaluation was 7.93 ± 3.26 mm (range 3-15 mm). Applied procedures were as follows: stent implantation (n: 8, 53.3%), stent implantation and polidocanol application (n: 4, 26.7%), only Argon Plasma Coagulation (APC) application (n: 2,13.3%), polidocanol application (n: 1,6.7%). Complete fistula closure was achieved in three of the 15 patients (20%). The procedures were partly successful in five (33.3%) patients and failed to be successful in seven (46.6%) patients. Survival rates in regard to procedural success were determined and a statistically significant difference was found in five-year survival rates (P = 0.027, P < 0.05). Conclusion: Our results demonstrated that bronchoscopic procedures can be safely and effectively performed in patients who were not eligible for surgery for various reasons.

The Journal of Infection in Developing Countries

Introduction: Fatality due to COVID-19 continues to be a challenge. Timely identification of crit... more Introduction: Fatality due to COVID-19 continues to be a challenge. Timely identification of critical COVID-19 patients is crucial for their close clinical follow-up and treatment. We aimed to identify the mortality predictors of critical COVID-19 patients. Methodology: We analyzed medical records of 232 out of 300 patients with COVID-19 hospitalized in the intensive care unit (ICU) whose medical records were available in the hospital database. Non-survivors and survivors were compared for parameters. Medical records of demographics, comorbidities, radiological signs, respiratory support, and laboratory tests on the first day of ICU admission were included. The durations of ICU stay and hospitalization were also evaluated. Results: The patients with Acute Physiology and Chronic Health Evaluation II (APACHE-II) score above 28.5 and the patients with blood urea nitrogen (BUN) above 45.5 mg/dL were significantly more mortal (95% CI: 0.701, p = 0.0001; 95% CI: 0.599, p = 0.022; respecti...

Medical Bulletin of Haseki

Journal of Personalized Medicine

It is important to identify cases of latent tuberculosis infection (LTBI) who are at risk for tub... more It is important to identify cases of latent tuberculosis infection (LTBI) who are at risk for tuberculosis (TB) reactivation. We aimed to evaluate the performance of interferon (IFN)-gamma-inducible protein 10 (IP-10) as a marker to detect LTBI in patients with inflammatory rheumatic diseases (IRD). This study comprised 76 consecutive subjects with IRD. Patients with a history of TB or having active TB were excluded. In all patients, IP-10 level was measured and tuberculin skin test (TST) and QuantiFERON-TB Gold In-Tube test (QFT-GIT) were performed. Seventy patients with complete test results were analyzed. Twenty-one (30%) QFT-GIT-positive patients were defined as having LTBI. IP-10 yielded 2197 pg/mL cut-off point. At this cut-off point, IP-10 showed 89% specificity with a sensitivity of 91% (AUC: 0.950, 95% CI 0.906–0.994). TST, QFT-GIT, and IP-10 were positive in 77.1%, 30%, and 44.3% of the patients, respectively. Concordance among the results of TST, QFT-GIT, and IP-10 tests ...

Medical Principles and Practice, 2021

Introduction: Galectin-3 is a multifunctional protein, the levels of which increase in the presen... more Introduction: Galectin-3 is a multifunctional protein, the levels of which increase in the presence of diseases that progress with pulmonary fibrosis. This study investigated the role of galectin-3 levels in the staging and assessing of the severity of sarcoidosis. Methods and Subjects: Seventy-three subjects were studied; 25 were healthy individuals and 48 patients had pathologically confirmed diagnosis of sarcoidosis in which other potential causes had been ruled out. Galectin-3 levels were measured and compared in terms of such parameters as hemogram, biochemistry, age, body mass index, and smoking status. Results: The mean galectin-3 levels of the sarcoidosis patients (14.87 ± 5.57) were significantly higher than those in the healthy subjects (11.81 ± 2.67), and the mean galectin-3 levels differed significantly among different stages of the disease (p < 0.05). The serum galectin-3 level in patients with stage 2, 3, and 4 sarcoidosis was found to be higher than in patients wit...

printing supported by . Visit Chiesi at Stand B2.10 MONDAY, SEPTEMBER 3RD 2012 pain. Multiple rib... more printing supported by . Visit Chiesi at Stand B2.10 MONDAY, SEPTEMBER 3RD 2012 pain. Multiple rib fractures were detected in five patients (41.7%). The fracture were detected most frequently between 4th and 9th ribs. 8 (66.66%) patients had COPD, 2 (16.66%) patients had bronchial asthma and 2(16.66%) patients had osteoporosis as well. The patients with COPD and bronchial asthma were treated with high dose steroids for over a year. Bone densitometry revealed high risk of bone fracture in all patients. Conclusion: Spontaneous rib fracture due to severe cough may occur in patients with osteoporosis or with COPD and bronchial asthma receiving long-term steroid therapy. If these patients have severe chest pain, chest radiography should be evaluated for bone lesions particularly. P2420 Analysis of 430 chest trauma patients in Kashan trauma center: 2003-2011 Abdoulhossein Davoodabadi. Surgery, Kashan Medical University, Kashan, Islamic Republic of Iran Background: Chest trauma as a potenti...

Aim: The aim of this study is to analyze COPD exacerbation rates and the effect of patients’ beha... more Aim: The aim of this study is to analyze COPD exacerbation rates and the effect of patients’ behavioral changes on the exacerbations during the pandemic. Materials and Methods: Conducted in a reference hospital for chest diseases, patients hospitalized with an exacerbation of COPD between 11.03.2019 and 11.03.2020 were designated. Patients’ COPD exacerbations requiring emergency department (ED) visits and/or hospitalization were compared between 11.03.2019 - 25.12.2019 (pre-pandemic period) and 11.03.2020 - 25.12.2020 (pandemic period). Each patient was surveyed with 25 questions using telemedicine. Results: Of all the 256 patients, 203 (79%) were male and the mean age was 66±10. Compared to the previous year, ED visits and hospitalizations in our hospital were significantly lower and less frequent (p<0.0001, for both). Smoking habit decreased in 9%, and 60% had hardly spent time in outdoors (e.g., parks and gardens). Only three patients reported to spend time indoors (e.g., cafe...