Oscar Rodriguez - Academia.edu (original) (raw)
Papers by Oscar Rodriguez
Bioorganic and Medicinal Chemistry, Mar 15, 2013
A small series of C-cinnamoyl glycosides incorporating the phenol moiety has been prepared by rea... more A small series of C-cinnamoyl glycosides incorporating the phenol moiety has been prepared by reaction of glycosyl ketones with the appropriate benzaldehydes. Glycosides were tested for the inhibition of twelve mammalian isoforms of carbonic anhydrase. This is the first study in which α-CAs have been investigated for their interaction with C-glycosides, a novel carbohydrate scaffold in the design of carbonic anhydrase inhibitors. The C-cinnamoyl glycosides were generally effective CA inhibitors, with inhibition constants in the low micromolar range against CA I, II, IV, VA, VB, VI, VII, IX, XII, XIII, XIV and ineffective inhibitors of CA III. These results confirm that attaching carbohydrate moieties to CA phenol pharmacophore improves its inhibitory activity.
Ces Medicina, Nov 17, 2009
International Journal of Multiphase Flow, 2006
Oil-water two-phase flow experiments were conducted in a 15 m long, 8.28 cm diameter, inclinable ... more Oil-water two-phase flow experiments were conducted in a 15 m long, 8.28 cm diameter, inclinable steel pipe using mineral oil (density of 830 kg/m 3 and viscosity of 7.5 mPa s) and brine (density of 1060 kg/m 3 and viscosity of 0.8 mPa s). Steady-state data on flow patterns, two-phase pressure gradient and holdup were obtained over the entire range of flow rates for pipe inclinations of À5°, À2°, À1.5°, 0°, 1°, 2°and 5°. The characterization of flow patterns and identification of their boundaries was achieved via observation of recorded movies and by analysis of the relative deviation from the homogeneous behavior. A stratified wavy flow pattern with no mixing at the interface was identified in downward and upward flow. Two gamma-ray densitometers allowed for accurate measurement of the absolute in situ volumetric fraction (holdup) of each phase for all flow patterns. Extensive results of holdup and two-phase pressure gradient as a function of the superficial velocities, flow pattern and inclinations are reported. The new experimental data are compared with results of a flow pattern dependent prediction model, which uses the area-averaged steady-state two-fluid model for stratified flow and the homogeneous model for dispersed flow. Prediction accuracies for oil/water holdups and pressure gradients are presented as function of pipe inclination for all flow patterns observed. There is scope for improvement for in particular dual-continuous flow patterns.
International Journal of Multiphase Flow, 2006
The aim of this study is to develop a model for the determination of the superficial velocities i... more The aim of this study is to develop a model for the determination of the superficial velocities in horizontal and slightly inclined oil-water pipe flow conditions by using pressure gradient and mixture density information. In this article an inverse model is suggested for a dispersion of oil in water and of water in oil. This approach permits to select dispersed flow conditions from a set of experimental data, and uses a new hybrid model for the effective viscosity. A set of 310 oil-water experimental data points collected on an experimental set-up of length L = 15 m and diameter D = 8.28 cm at various (slight) orientations is used to validate the inverse method. The comparison between model reconstructions and measured flow velocities show a reasonable agreement.
Hispania a Journal Devoted to the Teaching of Spanish and Portuguese, 2010
Comedias como La prudencia en la mujer o El burlador de Sevilla comprenden el capítulo designado ... more Comedias como La prudencia en la mujer o El burlador de Sevilla comprenden el capítulo designado a Tirso de Molina. Como sucedía con la primera obra de Lope, en La prudencia en la mujer, María de Molina encarna todas las virtudes del buen monarca. La siguiente obra, El burlador de Sevilla, sigue la misma trayectoria que se observaba en Lope de Vega, y Juan Tenorio personifica el punto culminante de la degeneración del poder. Las virtudes que ofrecía la primera comedia desaparecen y en la última obra reina el vicio, es decir, la prostitución, el erotismo, la escatología, la pasividad, la corrupción, la degradación y el disfraz en un mundo al revés en el que se carnavaliza el poder.
Revista Universidad Eafit, Jan 26, 2011
Ricyde Revista Internacional De Ciencias Del Deporte, 2007
Key words:perceived utility, physical activity and sport, scale and assessment, motivation to sport.
Key words:perceived utility, physical activity and sport, scale and assessment, motivation to sport.
Cancionero General, 2005
en concreto el que hoy reposa en la Biblioteca de El Escorial (X.II.15), se abre con unos curioso... more en concreto el que hoy reposa en la Biblioteca de El Escorial (X.II.15), se abre con unos curiosos versos seguramente redactados por el anónimo amanuense autor de esta copia, fechada en la primera mitad del siglo XVI. 2 El poemita, que creo es inédito (algo lógico teniendo en cuenta su escasa entidad), dice así:
Acta Biologica Colombiana, Sep 15, 2011
Un total de 315 aves, pertenecientes a 75 (23 familias) de Villavicencio y San Miguel (Meta, Colo... more Un total de 315 aves, pertenecientes a 75 (23 familias) de Villavicencio y San Miguel (Meta, Colombia) fueron examinadas para hematozoarios, donde 50 aves (15.9%) presentaron uno Acta Biologico Colombiana, Vol. 5 No.2, 2000 59 o mas hemoparasitos. Microfilaria fue e! hematozoano mas encontrado, seguido numericamente por: especies de Haemoproteus, Plasmodium y Trypanosoma y finalmente par un ejemplar de Hepatozoon. EI estudio incluye 15 nuevos registros hospedero-parasito para el mundo y 18 para
Different polarity Extracts and fractions from leaves and flowers of the plant species Chromolaen... more Different polarity Extracts and fractions from leaves and flowers of the plant species Chromolaena subscandens (Hieron.) R.M. King & H. Rob. were evaluated for activity against the bacteria Escherichia coli Staphylococcus aureus, and fungus Fusarium oxysporum using the methods of diffusion in gel by plate perforation and macrodilution in plate respectively. Eleven secondary metabolites were isolated and purified with the
Cereal Chemistry, Jul 1, 2006
Cereal Chem. 83(4):358-362 Plantago ovata F. are small tan-colored seeds with ≈30% weight husk. P... more Cereal Chem. 83(4):358-362 Plantago ovata F. are small tan-colored seeds with ≈30% weight husk. Plantago's husk high content of soluble fiber makes it a good lubricant of the intestinal track with demonstrated effects in lowering plasma choles- terol levels in humans and experimental animals. Plantago seeds grown in Northern Mexico were analyzed for proximate composition, combustion heat, soluble and insoluble
No Solo Usabilidad, Feb 28, 2003
... objetivos de la clasificación). Además, observe que en el modelo facetado, en la faceta &... more ... objetivos de la clasificación). Además, observe que en el modelo facetado, en la faceta 'temática', se ha añadido una subcategoría a la categoría 'Web Semántica', llamada 'Agentes Inteligentes'. Incorporar esta categoría al ...
Advanced Technology Optical Telescopes V, Jun 1, 1994
We describe a new telescope encoder that overcomes several traditional problems. The system uses ... more We describe a new telescope encoder that overcomes several traditional problems. The system uses a camera, a ruled scale, and a robust image processing algorithm to determine angular position. The ruled scale can be any of a variety of materials. The system is noncontacting, dirt insensitive, and has typical alignment tolerances of 0.25 mm.
Revista Cubana De Medicina Tropical, Feb 1, 1998
The possibility of detecting HIV-1 antibodies by an immunoblotting kit is studied in a panel of 1... more The possibility of detecting HIV-1 antibodies by an immunoblotting kit is studied in a panel of 125 known specimens of dried blood spotted on filter paper and their corresponding serum samples. No differences were observed in the patterns of bands with both types of samples or in the sensitivity and specificity, where 100% figures were attained, allowing to conclude that the blood specimen taken on filter paper may be used for the detection of HIV-1 antibodies by the DAVIH-BLOT system and may be kept at 4 degrees C during 30 weeks.
Bioorganic and Medicinal Chemistry, Mar 15, 2013
A small series of C-cinnamoyl glycosides incorporating the phenol moiety has been prepared by rea... more A small series of C-cinnamoyl glycosides incorporating the phenol moiety has been prepared by reaction of glycosyl ketones with the appropriate benzaldehydes. Glycosides were tested for the inhibition of twelve mammalian isoforms of carbonic anhydrase. This is the first study in which α-CAs have been investigated for their interaction with C-glycosides, a novel carbohydrate scaffold in the design of carbonic anhydrase inhibitors. The C-cinnamoyl glycosides were generally effective CA inhibitors, with inhibition constants in the low micromolar range against CA I, II, IV, VA, VB, VI, VII, IX, XII, XIII, XIV and ineffective inhibitors of CA III. These results confirm that attaching carbohydrate moieties to CA phenol pharmacophore improves its inhibitory activity.
Ces Medicina, Nov 17, 2009
International Journal of Multiphase Flow, 2006
Oil-water two-phase flow experiments were conducted in a 15 m long, 8.28 cm diameter, inclinable ... more Oil-water two-phase flow experiments were conducted in a 15 m long, 8.28 cm diameter, inclinable steel pipe using mineral oil (density of 830 kg/m 3 and viscosity of 7.5 mPa s) and brine (density of 1060 kg/m 3 and viscosity of 0.8 mPa s). Steady-state data on flow patterns, two-phase pressure gradient and holdup were obtained over the entire range of flow rates for pipe inclinations of À5°, À2°, À1.5°, 0°, 1°, 2°and 5°. The characterization of flow patterns and identification of their boundaries was achieved via observation of recorded movies and by analysis of the relative deviation from the homogeneous behavior. A stratified wavy flow pattern with no mixing at the interface was identified in downward and upward flow. Two gamma-ray densitometers allowed for accurate measurement of the absolute in situ volumetric fraction (holdup) of each phase for all flow patterns. Extensive results of holdup and two-phase pressure gradient as a function of the superficial velocities, flow pattern and inclinations are reported. The new experimental data are compared with results of a flow pattern dependent prediction model, which uses the area-averaged steady-state two-fluid model for stratified flow and the homogeneous model for dispersed flow. Prediction accuracies for oil/water holdups and pressure gradients are presented as function of pipe inclination for all flow patterns observed. There is scope for improvement for in particular dual-continuous flow patterns.
International Journal of Multiphase Flow, 2006
The aim of this study is to develop a model for the determination of the superficial velocities i... more The aim of this study is to develop a model for the determination of the superficial velocities in horizontal and slightly inclined oil-water pipe flow conditions by using pressure gradient and mixture density information. In this article an inverse model is suggested for a dispersion of oil in water and of water in oil. This approach permits to select dispersed flow conditions from a set of experimental data, and uses a new hybrid model for the effective viscosity. A set of 310 oil-water experimental data points collected on an experimental set-up of length L = 15 m and diameter D = 8.28 cm at various (slight) orientations is used to validate the inverse method. The comparison between model reconstructions and measured flow velocities show a reasonable agreement.
Hispania a Journal Devoted to the Teaching of Spanish and Portuguese, 2010
Comedias como La prudencia en la mujer o El burlador de Sevilla comprenden el capítulo designado ... more Comedias como La prudencia en la mujer o El burlador de Sevilla comprenden el capítulo designado a Tirso de Molina. Como sucedía con la primera obra de Lope, en La prudencia en la mujer, María de Molina encarna todas las virtudes del buen monarca. La siguiente obra, El burlador de Sevilla, sigue la misma trayectoria que se observaba en Lope de Vega, y Juan Tenorio personifica el punto culminante de la degeneración del poder. Las virtudes que ofrecía la primera comedia desaparecen y en la última obra reina el vicio, es decir, la prostitución, el erotismo, la escatología, la pasividad, la corrupción, la degradación y el disfraz en un mundo al revés en el que se carnavaliza el poder.
Revista Universidad Eafit, Jan 26, 2011
Ricyde Revista Internacional De Ciencias Del Deporte, 2007
Key words:perceived utility, physical activity and sport, scale and assessment, motivation to sport.
Key words:perceived utility, physical activity and sport, scale and assessment, motivation to sport.
Cancionero General, 2005
en concreto el que hoy reposa en la Biblioteca de El Escorial (X.II.15), se abre con unos curioso... more en concreto el que hoy reposa en la Biblioteca de El Escorial (X.II.15), se abre con unos curiosos versos seguramente redactados por el anónimo amanuense autor de esta copia, fechada en la primera mitad del siglo XVI. 2 El poemita, que creo es inédito (algo lógico teniendo en cuenta su escasa entidad), dice así:
Acta Biologica Colombiana, Sep 15, 2011
Un total de 315 aves, pertenecientes a 75 (23 familias) de Villavicencio y San Miguel (Meta, Colo... more Un total de 315 aves, pertenecientes a 75 (23 familias) de Villavicencio y San Miguel (Meta, Colombia) fueron examinadas para hematozoarios, donde 50 aves (15.9%) presentaron uno Acta Biologico Colombiana, Vol. 5 No.2, 2000 59 o mas hemoparasitos. Microfilaria fue e! hematozoano mas encontrado, seguido numericamente por: especies de Haemoproteus, Plasmodium y Trypanosoma y finalmente par un ejemplar de Hepatozoon. EI estudio incluye 15 nuevos registros hospedero-parasito para el mundo y 18 para
Different polarity Extracts and fractions from leaves and flowers of the plant species Chromolaen... more Different polarity Extracts and fractions from leaves and flowers of the plant species Chromolaena subscandens (Hieron.) R.M. King & H. Rob. were evaluated for activity against the bacteria Escherichia coli Staphylococcus aureus, and fungus Fusarium oxysporum using the methods of diffusion in gel by plate perforation and macrodilution in plate respectively. Eleven secondary metabolites were isolated and purified with the
Cereal Chemistry, Jul 1, 2006
Cereal Chem. 83(4):358-362 Plantago ovata F. are small tan-colored seeds with ≈30% weight husk. P... more Cereal Chem. 83(4):358-362 Plantago ovata F. are small tan-colored seeds with ≈30% weight husk. Plantago's husk high content of soluble fiber makes it a good lubricant of the intestinal track with demonstrated effects in lowering plasma choles- terol levels in humans and experimental animals. Plantago seeds grown in Northern Mexico were analyzed for proximate composition, combustion heat, soluble and insoluble
No Solo Usabilidad, Feb 28, 2003
... objetivos de la clasificación). Además, observe que en el modelo facetado, en la faceta &... more ... objetivos de la clasificación). Además, observe que en el modelo facetado, en la faceta 'temática', se ha añadido una subcategoría a la categoría 'Web Semántica', llamada 'Agentes Inteligentes'. Incorporar esta categoría al ...
Advanced Technology Optical Telescopes V, Jun 1, 1994
We describe a new telescope encoder that overcomes several traditional problems. The system uses ... more We describe a new telescope encoder that overcomes several traditional problems. The system uses a camera, a ruled scale, and a robust image processing algorithm to determine angular position. The ruled scale can be any of a variety of materials. The system is noncontacting, dirt insensitive, and has typical alignment tolerances of 0.25 mm.
Revista Cubana De Medicina Tropical, Feb 1, 1998
The possibility of detecting HIV-1 antibodies by an immunoblotting kit is studied in a panel of 1... more The possibility of detecting HIV-1 antibodies by an immunoblotting kit is studied in a panel of 125 known specimens of dried blood spotted on filter paper and their corresponding serum samples. No differences were observed in the patterns of bands with both types of samples or in the sensitivity and specificity, where 100% figures were attained, allowing to conclude that the blood specimen taken on filter paper may be used for the detection of HIV-1 antibodies by the DAVIH-BLOT system and may be kept at 4 degrees C during 30 weeks.