Osman Sinanovic - Academia.edu (original) (raw)
Papers by Osman Sinanovic
Materia socio-medica, 2017
Introduction: Research indicates that women victims of domestic violence show significant cogniti... more Introduction: Research indicates that women victims of domestic violence show significant cognitive changes, emotional numbing, and avoidance of interpersonal relationships. Aim: The aim of this research was to analyze emotional profile of women victims of domestic violence, and to determine the relationship between dimensions of emotions and frequency of women exposure to domestic violence. Methods: The research was conducted on the sample of 169 women, 111 were victims of domestic violence and 58 were women who did not experience domestic violence. Plutchik's Emotions Profile Index (EPI) was used for measuring of the emotion profile, and the Modified Inventory of Domestic Violence for measuring experiences of different types of violence. Basic socio-demographic data were also collected. Results: Significant differences between women victims of domestic violence and women who did not experience domestic violence were found in a few dimensions of emotional profile. Women victims of domestic violence had higher results in the dimensions of deprivation/depression and aggression/destruction, while women who did not experience domestic violence had higher results in dimensions of reproduction and incorporation. Aggression was in significant negative correlation with reproduction, incorporation and self protection, whereas it was significant positive correlation with deprivation and opposition. There were significant and positive correlation between the dimensions of aggression and deprivation and frequency of all three forms of domestic violence and age of women. Conclusion: According to results obtained in this research, it can be concluded that women victims of domestic violence have significantly more intensive negative emotional dimensions in comparison to women who were not abused. Women victims of domestic violence with higher frequency of abuse describe themselves as more sad, apathetic, lonely, angry, quarrelsome and less sociable. Prominence of negative emotions, deprivation and aggression, can be factor of risk for mental health disorders and for re-victimisation of women victims of domestic violence.
Rad Hrvatske akademije znanosti i umjetnosti, 2020
Introduction: Anomalous innervations of the extremities are common and influence the interpretati... more Introduction: Anomalous innervations of the extremities are common and influence the interpretation of electrophysiologic studies in normal subjects and those with peripheral nerve lesions. The aim of this study was to describe the most common innervation anomalies in upper and lower extremities and to point out their clinical repercussions. Methods: Article has an analytical character and review of literature, including some personal articles. Results and Discussion: Double innervation and communications among nerves are causes of anomalies of innervation of the skin and muscles. The fact of communications of fibers among nerves is better called "nerve communication" than "nerve anastomosis". Anomalous innervations of the upper and lower extremities are, therefore, common and influence on the interpretation of neurophysiological parameters during electromyoneurography. Namely, in the course of an electrodiagnostic investigation of a peripheral nerve lesion, the examiner may be confronted with unexpected findings in contradiction with the clinical picture. In this review, a description is given of the most common innervation anomalies in upper and lower extremities: median to ulnar nerve communication (Martin-Gruber anastomosis); ulnar to median nerve communication (Marinacci anastomosis/MA); variations in the innervation of intrinsic muscles of the hand (Riche-Cannieu anastomosis; Berrettini anastomosis); accessory deep peroneal nerve; and tibial to peroneal nerve communication. Conclusion: As anomalous innervations of the extremities are common and influence the interpretation of electrophysiological studies in normal subjests and those with peripheral nerve lesions, detailed anatomical knowledge is essential for accurate interpretation of physical examination, electrophysiological findings, diagnosis, prognosis and reducing the risk of iatrogenic injuries during surgical procedures. If these variations are not given due regard, errors and other consequences will be inevitable.
![Research paper thumbnail of Neonatal Risk Factors for Obstetric Brachial Plexus Lesions [Article in Bosnian]](https://attachments.academia-assets.com/120313834/thumbnails/1.jpg)
](The Central European Journal of Paediatrics, Jan 10, 2007
Cilj rada Otkriti moguće rizične faktore u novorođenčeta za nas tanak porođajne povrede brahijaln... more Cilj rada Otkriti moguće rizične faktore u novorođenčeta za nas tanak porođajne povrede brahijalnog pleksusa. Ispitanici i metode Studijom parova retrospektivno su analizira ni podaci o pojavi paralize pleksusa brahijalisa u porođaju 45503 novorođenčeta u periodu od 1. januara 1996. do 31. decembra 2004. u Klinici za ginekologiju i akušerstvo Univerzitetskokliničkog centra u Tuzli. U istraženoj populaciji otkriveno je 86 novorođenčadi s povredom pleksusa brahijalisa (ispitanici). Kon trolnu grupu sačinjava 86 novorođenčadi bez povrede pleksusa brahijalisa, izabranih nasumce kao slučajni uzorak iz iste popu lacije (kontrolna grupa). Ispitanici i kontrolna grupa uspoređeni su međusobno s obzirom na spol, trajanje gestacije, raspodjelu porođajnih težina, prezentaciju ploda pri porođaju, te s obzirom na Apgar-skor nakon prve i pete minute. Statistička značajnost rezultata procijenjena je 2 testom. Rezultati Između ispitanika i kontrolnih nije bilo razlike u spolu. Nađena je vrlo značajna razlika u distribuciji porođajnih težina: frekvencija ispitanika s porođajnim težinama od 4000 do 4599 grama, a osobito s težinama većim od 4500 g bila je vrlo značajno viša nego u istim težinskim skupinama kontrolnih. Razlika u učestalosti okcipitalne prezentacije u porodu u korist ispitanika nije bila statistički značajna. Među ispitanicima bio je znatno više nego u kontrolnih zastupljen niski Apgar-skor (7) nakon prve i pete minute. U 35 od 86 (42,5%) ispitanika utvrđena je udružena fraktura klavikule, a u po jednog, fraktura humerusa i rebara. Zaključak Najizraženiji rizični faktori su porođajna težina preko 4000 g i nizak Apgar-skor kao odraz traumatičnog porođaja, dok u našem istraživanju, karlični položaj ploda, kao rizični faktor nije statistički dokazan.
Acta informatica medica : AIM : journal of the Society for Medical Informatics of Bosnia & Herzegovina : časopis Društva za medicinsku informatiku BiH, 2021
Background: The accessory deep peroneal nerve (ADPN) is as an anomalous nerve derived from the su... more Background: The accessory deep peroneal nerve (ADPN) is as an anomalous nerve derived from the superficial peroneal nerve or its branch and supplies motor innervations for extensor digitorum brevis (EDB) and sensory innervations for the lateral part of the ankle and foot regions. It is the most common anomalous innervation present in the lower limb. Objective: The aim of this study was to determine the prevalence of ADPN electrophysiologically in a sample of Bosnia and Herzegovina subjects who referred to an electromyography lab. Methods: This cross-sectional descriptive study included 316 lower limbs from 171 subjects referred for electrodiagnostic studies to Electromyography Lab, Department of Neurology, University Clinical Center Tuzla (Bosnia and Herzegovina) (102 females/60% and 69/40%) males). Motor nerve conduction studies for the peroneal nerve and ADPN were done. Compound muscle action potential (CMAP) and nerve conduction velocity (NCV) of deep peroneal nerve (DPN) were measured by using EMG machine by stimulating DPN at knee, ankle and lateral malleolus areas accordingly, with recording from extensor digitorum brevis (EDB) muscle. Results: ADPN was found in 46 (14.5%) of 316 legs. ADPN was found in 18 (39.1%) right lower limbs and 28 (60.9%) left lower limbs. Ten subjects (5.8%) had bilateral ADPN. There was no statistically significant difference between the occurrence of ADPN in women versus men (p=0.757), as well as in right versus left legs (p=0.237). Conclusion: This study demonstrated that ADPN prevalence, in a sample of Bosnia and Herzegovina subjects who referred to an electromyography lab is 14.5%. Recognition of ADPN is very important for proper interpretation of lower limbs electrophysiological data.
Cureus, 2022
Coronavirus disease 2019 (COVID-19) is primarily a disease of the respiratory system but severe a... more Coronavirus disease 2019 (COVID-19) is primarily a disease of the respiratory system but severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) may cause several immune-related complications including different neurological disorders, such as myelopathy with paraparesis. In this atypical case a female patient with progressive spastic paraparesis after COVID-19 infection, brisk reflexes and positive Babinski sign, reduced vibratory sensation to the thoracic level, elevated immunoglobulin levels (IgG) in cerebrospinal fluid, but negative magnetic resonance imaging (MRI) of the brain and spine, is presented. A 57-year-old woman with spastic paraparesis and inability to walk was admitted to our neurological department. About four months before hospitalization, she started feeling numbness and tingling in the feet and lumbar spine area. Gradually, numbness and tingling ascended to the thoracic spine level Th7/8, and she developed weakness mostly in her legs. In the neurological exam she had spastic paraparesis. MRI of the brain, cervical and thoracic spine did not reveal any signal abnormality. Serological testing for SARS-CoV-2 was performed and results were highly positive IgG and IgM+IgA levels. The lumbar puncture finding confirmed the suspicion of immune-related complications after SARS-CoV-2 infection (intrathecal IgG synthesis). This case draws attention to spastic paraparesis or progressive MRI-negative myelitis after SARS-CoV-2 infection, which obviously has immune-mediated pathogenesis that happen in response to the virus or its antibodies. Similarities in spastic paraparesis after human T-lymphotropic virus (HTLV-1) or human immunodeficiency virus (HIV-1) and SARS-CoV-2 infections were observed. The patient had a good response to corticosteroid therapy and had good recovery.
Knj. 52-53(2020), 2020
Introduction: Anomalous innervations of the extremities are common and influence the interpretati... more Introduction: Anomalous innervations of the extremities are common and influence the interpretation of electrophysiologic studies in normal subjects and those with peripheral nerve lesions. The aim of this study was to describe the most common innervation anomalies in upper and lower extremities and to point out their clinical repercussions. Methods: Article has an analytical character and review of literature, including some personal articles. Results and Discussion: Double innervation and communications among nerves are causes of anomalies of innervation of the skin and muscles. The fact of communications of fibers among nerves is better called "nerve communication" than "nerve anastomosis". Anomalous innervations of the upper and lower extremities are, therefore, common and influence on the interpretation of neurophysiological parameters during electromyoneurography. Namely, in the course of an electrodiagnostic investigation of a peripheral nerve lesion, the examiner may be confronted with unexpected findings in contradiction with the clinical picture. In this review, a description is given of the most common innervation anomalies in upper and lower extremities: median to ulnar nerve communication (Martin-Gruber anastomosis); ulnar to median nerve communication (Marinacci anastomosis/MA); variations in the innervation of intrinsic muscles of the hand (Riche-Cannieu anastomosis; Berrettini anastomosis); accessory deep peroneal nerve; and tibial to peroneal nerve communication. Conclusion: As anomalous innervations of the extremities are common and influence the interpretation of electrophysiological studies in normal subjests and those with peripheral nerve lesions, detailed anatomical knowledge is essential for accurate interpretation of physical examination, electrophysiological findings, diagnosis, prognosis and reducing the risk of iatrogenic injuries during surgical procedures. If these variations are not given due regard, errors and other consequences will be inevitable.
Introduction: Carpal tunnel syndrome (CTS) is a collection of characteristic symptoms and signs t... more Introduction: Carpal tunnel syndrome (CTS) is a collection of characteristic symptoms and signs that occurs following compression of the median nerve within the carpal tunnel. The prevalence of electrophysiologically confirmed CTS in working populations is generally higher than in the general population. The aim was to present association between carpal tunnel syndrome and the excessive use of computer mouse and keyboard in young adult with presence of Martin-Gruber anastomosis. Case report: We presented the development of carpal tunnel syndrome in 17-year-old male, following the repetitive movement of the right wrist, due to excessive use of the computer mouse and keyboard. During the neurological examination, we found pronounced hypotrophy of the first interosseous dorsalis space (weakness of m. adductor pollicis), and mild hypotrophy of the thenar muscle. Nerve conduction velocities of n. ulnaris and n. medianus on the right hand were normal, but with prolonged value of distal la...
Acta Medica Saliniana, 2009
Generally, Arnold – Chiari malformation associated with syringomyelia is not rare. In this case r... more Generally, Arnold – Chiari malformation associated with syringomyelia is not rare. In this case report we present a 52 years old female patient with a history of neck-pain, low-back pain, pain in both arms as well as frequent numbness in the lateral regions of both arms. She also experienced walk disturbance and in her previous history she reports a car accident, twenty-eight years ago. She broke windshield with her forehead, but remained conscious at the time. At the time of admittance at the Department of Neurology, her neurological status was remarkable for cerebellar symptomatology (ataxia, positive Romberg-sign, «finger–nose» test which she did with tremor and was not able to perform «tandem-walk»), hypoestesia of the right side of the body, hyper-reflection of both arms and legs, bilaterally, more pronounced at the right side; right foot subclonus and spastic-ataxic walk. Neurological status could not be explained by previously performed tests: x-ray of cervical spine, lumbal ...
Acta Medica Saliniana, 2008
Introduction: Subarachnoid haemorrhage presents urgent state in neurology, with dramatic clinical... more Introduction: Subarachnoid haemorrhage presents urgent state in neurology, with dramatic clinical picture and high mortality. Aim of this study was to analize role of the risk factors in prognosis of patients with spontaneous subarachnoidal haemorrhage. Patients and Methods: It was analyzed 48 patients with spontaneous subarachnoidal haemorrhage which are cured on Neurological clinic in Tuzla in period from January 1. 2001 till December 31. 2002. Mean age of patients was 57.6 +/-12. years. Results: It was shown that the most frequent risk factors were hypertension (72.9%), heart diseases (54.1%) and smoking (39.6%). From all 48, 21 (43.7%) patients died. At survived patients, one month from begining of disease, cases. Survived had significant lower mean age (p= .009) and Hunt Hess score (p=0.001) at admission than the died. Patients with complexity find by computed tomography had bad prognosis. Conclusion: Older age of patients, higher number of risk factors, higher Hunt Hess score ...
European Neuropsychopharmacology, 2018
ANOVA (probe test and immunohistochemistry) followed by post hoc Fisher LSD test. In vitro: one-w... more ANOVA (probe test and immunohistochemistry) followed by post hoc Fisher LSD test. In vitro: one-way ANOVA followed by post hoc Tukey test. Results: Ts were severely impaired in various learning and memory parameters (po0.01) and had fewer new neurons (DCX + cells/100 mm) in the DG (-37%; po0.05) in comparison with Eu. Treatment with tideglusib did not improve either memory or neurogenesis. Similarly to adults, tideglusib-treated Ts pups underwent no neurogenesis increase, indicating that the lack of effects of tideglusib on neurogenesis is not age-dependent. Interestingly, vehicle alone (corn oil) improved behavior in adults and neurogenesis both in adults (+39%; po0.05) and pups (+ 26%; po0.001). The absence of these effects in Ts that received vehicle + tideglusib suggests that tideglusib counteracts the positive effects of the vehicle. In vitro experiments showed that i) a wide range of tideglusib concentrations (0.1-10.0mM) was unable to enhance neurogenesis of Ts NPCs; ii) exposure to OA or LA, the main components of corn oil, enhanced proliferation (+ 40-65%; po0.001); iii) the effect of OA and LA was abrogated by co-exposure to tideglusib. Conclusion: The finding that tideglusib does not improve neurogenesis and behavior indicates that it is not a suitable treatment for DS. The finding that the fatty acids present in the vehicle (OA and LA) have a pro-neurogenic effect suggests that agonists of fatty acid receptors may represent a good strategy to ameliorate brain development in individuals with DS.
![Research paper thumbnail of Neonatal Risk Factors for Obstetric Brachial Plexus Lesions [Article in Bosnian]](https://attachments.academia-assets.com/120313866/thumbnails/1.jpg)
](Paediatrics Today, Jan 10, 2007
Cilj rada Otkriti moguće rizične faktore u novorođenčeta za nas tanak porođajne povrede brahijaln... more Cilj rada Otkriti moguće rizične faktore u novorođenčeta za nas tanak porođajne povrede brahijalnog pleksusa. Ispitanici i metode Studijom parova retrospektivno su analizira ni podaci o pojavi paralize pleksusa brahijalisa u porođaju 45503 novorođenčeta u periodu od 1. januara 1996. do 31. decembra 2004. u Klinici za ginekologiju i akušerstvo Univerzitetskokliničkog centra u Tuzli. U istraženoj populaciji otkriveno je 86 novorođenčadi s povredom pleksusa brahijalisa (ispitanici). Kon trolnu grupu sačinjava 86 novorođenčadi bez povrede pleksusa brahijalisa, izabranih nasumce kao slučajni uzorak iz iste popu lacije (kontrolna grupa). Ispitanici i kontrolna grupa uspoređeni su međusobno s obzirom na spol, trajanje gestacije, raspodjelu porođajnih težina, prezentaciju ploda pri porođaju, te s obzirom na Apgar-skor nakon prve i pete minute. Statistička značajnost rezultata procijenjena je 2 testom. Rezultati Između ispitanika i kontrolnih nije bilo razlike u spolu. Nađena je vrlo značajna razlika u distribuciji porođajnih težina: frekvencija ispitanika s porođajnim težinama od 4000 do 4599 grama, a osobito s težinama većim od 4500 g bila je vrlo značajno viša nego u istim težinskim skupinama kontrolnih. Razlika u učestalosti okcipitalne prezentacije u porodu u korist ispitanika nije bila statistički značajna. Među ispitanicima bio je znatno više nego u kontrolnih zastupljen niski Apgar-skor (7) nakon prve i pete minute. U 35 od 86 (42,5%) ispitanika utvrđena je udružena fraktura klavikule, a u po jednog, fraktura humerusa i rebara. Zaključak Najizraženiji rizični faktori su porođajna težina preko 4000 g i nizak Apgar-skor kao odraz traumatičnog porođaja, dok u našem istraživanju, karlični položaj ploda, kao rizični faktor nije statistički dokazan.
![Research paper thumbnail of Acute Disseminated Encephalomyelitis and Multiple Sclerosis in Children [Article in Bosnian]](https://attachments.academia-assets.com/120313873/thumbnails/1.jpg)
](Paediatrics Today, May 21, 2006
Akutni diseminirani encefalomijelitis (ADEM) je u pravilu monofazična, imunološki uslovljena, bol... more Akutni diseminirani encefalomijelitis (ADEM) je u pravilu monofazična, imunološki uslovljena, bolest u kojoj se stvaraju multifokalne demijelinizirajuće lezije u centralnom nervnom sistemu (CNS). Međutim, ADEM se može manifestirati i multiplim relapsima bolesti sličnih multiploj sklerozi (MS). U pravilu je to bolest dječijeg doba (prije 10. godine života). ADEM može biti prva faza MS u oko 25% djece. Bolest nastaje akutno, a klinička slika zavisi od intenziteta procesa, odnosno zahvaćenih dijelova CNS-a. Odgovara infektivnom sindromu sa afekcijom meninga i različitih dijelova mozga i kičmene moždine. Prognoza je vrlo neizvjesna, sa letalnim završetkom kod oko 1/3 slučajeva. MS je hronična inflamatorna, nekontaginozna, progresivna multifokalna demijelinizirajuća, autoimuna bolest CNS (bijele mase mozga i kičmene moždine) koja se može manifestirati različitim neurološkim simptomima. Simptomi se najčešće (85-90%) javljaju u atacima (egzacerbacijama ili remisijama) ili sporo progresivno tokom vremena. Uzrok MS-e kao i patogeneza i danas nisu dovoljno poznati. Nasljedni faktori imaju važnu, vjerovatno predisponirajuću ulogu. Patogeneza MS uključuje inflamaciju, demijelinizaciju i gubitak aksona. MS se može pojaviti u bilo kom životnom dobu, a najčešće se javlja u trećoj ili četvrtoj deceniji. Pojava u djetinjstvu se procjenjuje na 3-5% slučajeva i smatra se da bar 2.5 do 5% od svih pacijenata sa MS prvu ataku bolesti doživi prije 16-og rođendana. Pojava prije desete godine je rijetkost i procjenjuje se da se javlja u 0.2% djece ovog uzrasta. Pretrage koje je potrebno napraviti prije nego se definitivno postavi dijagnoza ADEM-a i/ili MS-e su analiza cerebrospinalnog likvora, evocirani moždani potencijali, nuklearna magnetska rezonanca mozga i kičmene moždine. Također, potrebno je uraditi i nalaz kompjuterizirane tomografije mozga čije značenje nije u postavljanju dijagnoze MS-e, već u isključivanju postojanja drugih oštećenja mozga vaskularnog, tumorskog i drugog porijekla. Za sigurnu dijagnozu MS-a, danas su na snazi revidirani dijagnostički McDonaldovi kriterijumi iz 2001. godine, tzv. McDonaldovi kriterijumi 2005. U slučaju ADEM-a primjenjuje se antiinflamatorna (kortikosteroidi) i imunosupresivna terapija, u biti na isti način kao UVOD Mijelin je lipoproteinska membrana koja omotava aksone nervnih vlakana. Pripada mu 50% suhog ostatka bijele mase mozga. Sastav mijelina se unekoliko razlikuje u perifernom i centralnom nervnom sistemu. Čine ga holesterol, ADEM i MS u dječijoj dobi
Body dissatisfaction can be defined as a perceptive component of body image, as a difference betw... more Body dissatisfaction can be defined as a perceptive component of body image, as a difference between ideal body and a current body size. Body dissatisfaction is present not only in women who have eating disorders but in non-clinical population as well and to such extent that many American psychologists consider it a normative aspect of women's identity. The goal of this study was to investigate the presence of body dissatisfaction in non-clinical population of women in Bosnia and Herzegovina and to determine the differences in the level of body dissatisfaction between younger and mature women. It was predicted that body dissatisfaction would be present in women regardless of their age and that young women would demonstrate higher levels of body dissatisfaction than older women. 215 women were divided into young (≥25) and mature (≤40) groups and completed Stunkard's body figure rating scale and a demographic questionnaire. Results were consistent with the hypothesis. Women showed body dissatisfaction while age showed to be a significant factor. Socio-cultural perspective on body dissatisfaction was used in discussing the results.
Acta myologica : myopathies and cardiomyopathies : official journal of the Mediterranean Society of Myology / edited by the Gaetano Conte Academy for the study of striated muscle diseases, 2013
The accessory deep peroneal (ADPN) nerve has been regarded as an anomalous nerve derived from the... more The accessory deep peroneal (ADPN) nerve has been regarded as an anomalous nerve derived from the superficial peroneal nerve or its branch and supplies motor innervations for extensor digitorum brevis (EDB) and sensory innervations for the lateral part of the ankle and foot regions. The EDB is usually innervated exclusively by the deep peroneal nerve, a major branch of the the common peroneal nerve, however, in as many as 28% of patients (with same male/female frequency), one or both of the EDB muscles are (partially or exclusively) innervated by the ADPN nerve. This anomaly appears to be inherited in autosomal dominant fashion with incomplete gene penetrance. ADPN existence is of great clinical and surgical importance, and the aim of this study is to describe a very rare case of coexistence ADPN and anterior tarsal tunnel syndrome.
Bosnian journal of basic medical sciences / Udruženje basičnih mediciniskih znanosti = Association of Basic Medical Sciences, 2008
The objective of the study was to analyze the doppler sonography findings of vertebrobasilar circ... more The objective of the study was to analyze the doppler sonography findings of vertebrobasilar circulation (VB) in patients with Parkinson's disease. 40 patients were analyzed (25 men's and 15 women) with Parkinson's disease, average age was 61.9 years (SD=11.43), treated at the Clinic for Neurology in Tuzla. Device for doppler sonography was Multidop x 4. Doppler sonography findings of VB circulation were analyzed in order to computerized tomography (CT) findings of the brain (with or without ischemic lacunar lesions) and in order to presence of postural disturbances as one of dominant Parkinson's disease symptoms during actual hospitalization. Our results suggest that vertebrobasilar insufficiency is more frequent in patients with Parkinson's disease (no matter of type) and postural disturbances as a dominant symptom comparing to group of Parkinson's disease patients without postural disturbances. These results implicate the importance of doppler sonography f...
Bosnian journal of basic medical sciences / Udruženje basičnih mediciniskih znanosti = Association of Basic Medical Sciences, 2008
Intracerebral hemorrhage is the deadliest, most disabling and least treatable form of stroke desp... more Intracerebral hemorrhage is the deadliest, most disabling and least treatable form of stroke despite progression in medical science. The aim of the study was to analyze the frequency, risk factors, localization and 30-day prognosis in patients with intracerebral hemorrhage. We analyzed 352 patients with intracerebral hemorrhage (ICH) hospitalized at the Department of Neurology Tuzla during a three-year follow up. The following data were collected for all patients in a computerized database: age, sex, risk factors (hypertension, heart diseases, diabetes and smoking) and CT findings. Stroke severity was estimated with Scandinavian Stroke Scale, ICH topography was specified by CT, and outcome at 1st month after onset included information on vital status and disability (modified Rankin Scale, mRS). The most frequent risk factors were hypertension (84%), heart diseases (31%), cigarette smoking (28%) and diabetes mellitus (14%). The most frequent localization of ICH was multilobar (38%), ...
Bosnian journal of basic medical sciences / Udruženje basičnih mediciniskih znanosti = Association of Basic Medical Sciences, 2006
It was performed electroneurographic (ENG) studies with surface electrodes and examined nervus me... more It was performed electroneurographic (ENG) studies with surface electrodes and examined nervus medianus (NM) in 60 patients (38 females), average age of 50,28 years (X+/-SD=50,28+/-11), with clinical diagnosis of carpal tunnel syndrome (CTS) and at least one border or discrete abnormal value of conventional electrophysiological tests. It was also examined 57 healthy individuals (33 females) as control group, average age of 45,65 years (X+/-SD=45,65+/-9,68). The sensitivity and specificity of sensory-motor index (SMI), terminal latency index (TLI) and residual latency (RL) were calculated and compared. SMI is determinate by using following formula: distal distance (DD) (in cm)/distal motor latency (DML) (in ms) + sensory conduction velocity (SCV) (in m/s)/motor conduction velocity (MCV) (in m/s) of NM. SCV of NM was measured by antidromic technique in segment wrist-index finger and MCV of NM in forearm segment above wrist. SMI mean value of control group was 3,45 (X+/-SD=3,45+/-0,45)...
Bosnian journal of basic medical sciences / Udruzenje basicnih mediciniskih znanosti = Association of Basic Medical Sciences, 2002
A prospective case study was conducted in the Department of Occupational Medicine, Tuzla. The pur... more A prospective case study was conducted in the Department of Occupational Medicine, Tuzla. The purpose of this study was to indicate negative effects from occupational exposure to mercury on behavioural and mental health, memory and psychomotor function that was tested in 46 chloral-alkali plant workers (mean age was 38. 8+/- 5. 7 years; mean age of occupational history 16. 5+/- 6. 0 years). Data on toxicological monitoring on atomic absorption spectrometer, and data on mental health were collected, psychiatric and other subjective symptoms, and behavioural, psychomotor and memory function tested. The data were compared to control group, 32 healthy non exposed workers. The study was designed to assess blood and urine mercury levels and length of occupational exposure and investigate its relationships to effects on the mental health. The mean air mercury levels were 0.23 mg/m3, the mean blood mercury concentrations was 3. 6 mg/ dl and the mean urine mercury concentrations were 151.7 +...
Acta Medica Academica, 2012
The Journal of Maternal-Fetal & Neonatal Medicine, 2006
The 86 newborns with brachial plexus palsy have been recorded, the prevalence is 1.86 per 1000 li... more The 86 newborns with brachial plexus palsy have been recorded, the prevalence is 1.86 per 1000 live-born children. Analyzing maternal and neonatal factors, and the delivery pattern itself, it has been found that the highest risk-factors for brachial plexus injury are birth weight over 4000 grams, precipitous second stage of labor (<15 minutes), and vacuum-extractor assisted delivery of newborns. Brachial plexus palsy was more frequent when the newborns' mothers were overweight, with a body mass index ³29 kg/m 2. None of the parturient women, whose newborns were diagnosed with brachial plexus palsy, had a narrowed pelvis. Newborns, who were delivered vaginally, were not diagnosed to have a higher frequency of brachial plexus palsy compared to newborns who were delivered by Caesarean section, but newborns with vaginal breech delivery have had a higher incidence of brachial plexus palsy. Newborns, whose mothers were older than 35, had have brachial plexus palsy more frequently; statistically significant difference between primiparas and multiparas was not found. A total of 39 newborns (45.2%) were diagnosed to have a fracture of clavicle, which was the most frequently combined damage with brachial plexus injury. The 42 newborns (48.8%) had an Apgar score of £7 in the first minute after delivery, which indicates intrapartal distress of fetus and points to traumatic nature of these deliveries. Average birth weight of newborns with plexus brachialis damage was 3858±grames, which, for an average gestation age of 38.8±1,8 weeks of gestation, corresponds to eutrophic newborns. Both male and female newborns were diagnosed to have plexus brachialis equally and almost all deliveries (97.7%) started spontaneously. The majority of newborns were born early in the morning between 2-3 hours or afternoon between 14-15 hours.
Materia socio-medica, 2017
Introduction: Research indicates that women victims of domestic violence show significant cogniti... more Introduction: Research indicates that women victims of domestic violence show significant cognitive changes, emotional numbing, and avoidance of interpersonal relationships. Aim: The aim of this research was to analyze emotional profile of women victims of domestic violence, and to determine the relationship between dimensions of emotions and frequency of women exposure to domestic violence. Methods: The research was conducted on the sample of 169 women, 111 were victims of domestic violence and 58 were women who did not experience domestic violence. Plutchik's Emotions Profile Index (EPI) was used for measuring of the emotion profile, and the Modified Inventory of Domestic Violence for measuring experiences of different types of violence. Basic socio-demographic data were also collected. Results: Significant differences between women victims of domestic violence and women who did not experience domestic violence were found in a few dimensions of emotional profile. Women victims of domestic violence had higher results in the dimensions of deprivation/depression and aggression/destruction, while women who did not experience domestic violence had higher results in dimensions of reproduction and incorporation. Aggression was in significant negative correlation with reproduction, incorporation and self protection, whereas it was significant positive correlation with deprivation and opposition. There were significant and positive correlation between the dimensions of aggression and deprivation and frequency of all three forms of domestic violence and age of women. Conclusion: According to results obtained in this research, it can be concluded that women victims of domestic violence have significantly more intensive negative emotional dimensions in comparison to women who were not abused. Women victims of domestic violence with higher frequency of abuse describe themselves as more sad, apathetic, lonely, angry, quarrelsome and less sociable. Prominence of negative emotions, deprivation and aggression, can be factor of risk for mental health disorders and for re-victimisation of women victims of domestic violence.
Rad Hrvatske akademije znanosti i umjetnosti, 2020
Introduction: Anomalous innervations of the extremities are common and influence the interpretati... more Introduction: Anomalous innervations of the extremities are common and influence the interpretation of electrophysiologic studies in normal subjects and those with peripheral nerve lesions. The aim of this study was to describe the most common innervation anomalies in upper and lower extremities and to point out their clinical repercussions. Methods: Article has an analytical character and review of literature, including some personal articles. Results and Discussion: Double innervation and communications among nerves are causes of anomalies of innervation of the skin and muscles. The fact of communications of fibers among nerves is better called "nerve communication" than "nerve anastomosis". Anomalous innervations of the upper and lower extremities are, therefore, common and influence on the interpretation of neurophysiological parameters during electromyoneurography. Namely, in the course of an electrodiagnostic investigation of a peripheral nerve lesion, the examiner may be confronted with unexpected findings in contradiction with the clinical picture. In this review, a description is given of the most common innervation anomalies in upper and lower extremities: median to ulnar nerve communication (Martin-Gruber anastomosis); ulnar to median nerve communication (Marinacci anastomosis/MA); variations in the innervation of intrinsic muscles of the hand (Riche-Cannieu anastomosis; Berrettini anastomosis); accessory deep peroneal nerve; and tibial to peroneal nerve communication. Conclusion: As anomalous innervations of the extremities are common and influence the interpretation of electrophysiological studies in normal subjests and those with peripheral nerve lesions, detailed anatomical knowledge is essential for accurate interpretation of physical examination, electrophysiological findings, diagnosis, prognosis and reducing the risk of iatrogenic injuries during surgical procedures. If these variations are not given due regard, errors and other consequences will be inevitable.
The Central European Journal of Paediatrics, Jan 10, 2007
Cilj rada Otkriti moguće rizične faktore u novorođenčeta za nas tanak porođajne povrede brahijaln... more Cilj rada Otkriti moguće rizične faktore u novorođenčeta za nas tanak porođajne povrede brahijalnog pleksusa. Ispitanici i metode Studijom parova retrospektivno su analizira ni podaci o pojavi paralize pleksusa brahijalisa u porođaju 45503 novorođenčeta u periodu od 1. januara 1996. do 31. decembra 2004. u Klinici za ginekologiju i akušerstvo Univerzitetskokliničkog centra u Tuzli. U istraženoj populaciji otkriveno je 86 novorođenčadi s povredom pleksusa brahijalisa (ispitanici). Kon trolnu grupu sačinjava 86 novorođenčadi bez povrede pleksusa brahijalisa, izabranih nasumce kao slučajni uzorak iz iste popu lacije (kontrolna grupa). Ispitanici i kontrolna grupa uspoređeni su međusobno s obzirom na spol, trajanje gestacije, raspodjelu porođajnih težina, prezentaciju ploda pri porođaju, te s obzirom na Apgar-skor nakon prve i pete minute. Statistička značajnost rezultata procijenjena je 2 testom. Rezultati Između ispitanika i kontrolnih nije bilo razlike u spolu. Nađena je vrlo značajna razlika u distribuciji porođajnih težina: frekvencija ispitanika s porođajnim težinama od 4000 do 4599 grama, a osobito s težinama većim od 4500 g bila je vrlo značajno viša nego u istim težinskim skupinama kontrolnih. Razlika u učestalosti okcipitalne prezentacije u porodu u korist ispitanika nije bila statistički značajna. Među ispitanicima bio je znatno više nego u kontrolnih zastupljen niski Apgar-skor (7) nakon prve i pete minute. U 35 od 86 (42,5%) ispitanika utvrđena je udružena fraktura klavikule, a u po jednog, fraktura humerusa i rebara. Zaključak Najizraženiji rizični faktori su porođajna težina preko 4000 g i nizak Apgar-skor kao odraz traumatičnog porođaja, dok u našem istraživanju, karlični položaj ploda, kao rizični faktor nije statistički dokazan.
Acta informatica medica : AIM : journal of the Society for Medical Informatics of Bosnia & Herzegovina : časopis Društva za medicinsku informatiku BiH, 2021
Background: The accessory deep peroneal nerve (ADPN) is as an anomalous nerve derived from the su... more Background: The accessory deep peroneal nerve (ADPN) is as an anomalous nerve derived from the superficial peroneal nerve or its branch and supplies motor innervations for extensor digitorum brevis (EDB) and sensory innervations for the lateral part of the ankle and foot regions. It is the most common anomalous innervation present in the lower limb. Objective: The aim of this study was to determine the prevalence of ADPN electrophysiologically in a sample of Bosnia and Herzegovina subjects who referred to an electromyography lab. Methods: This cross-sectional descriptive study included 316 lower limbs from 171 subjects referred for electrodiagnostic studies to Electromyography Lab, Department of Neurology, University Clinical Center Tuzla (Bosnia and Herzegovina) (102 females/60% and 69/40%) males). Motor nerve conduction studies for the peroneal nerve and ADPN were done. Compound muscle action potential (CMAP) and nerve conduction velocity (NCV) of deep peroneal nerve (DPN) were measured by using EMG machine by stimulating DPN at knee, ankle and lateral malleolus areas accordingly, with recording from extensor digitorum brevis (EDB) muscle. Results: ADPN was found in 46 (14.5%) of 316 legs. ADPN was found in 18 (39.1%) right lower limbs and 28 (60.9%) left lower limbs. Ten subjects (5.8%) had bilateral ADPN. There was no statistically significant difference between the occurrence of ADPN in women versus men (p=0.757), as well as in right versus left legs (p=0.237). Conclusion: This study demonstrated that ADPN prevalence, in a sample of Bosnia and Herzegovina subjects who referred to an electromyography lab is 14.5%. Recognition of ADPN is very important for proper interpretation of lower limbs electrophysiological data.
Cureus, 2022
Coronavirus disease 2019 (COVID-19) is primarily a disease of the respiratory system but severe a... more Coronavirus disease 2019 (COVID-19) is primarily a disease of the respiratory system but severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) may cause several immune-related complications including different neurological disorders, such as myelopathy with paraparesis. In this atypical case a female patient with progressive spastic paraparesis after COVID-19 infection, brisk reflexes and positive Babinski sign, reduced vibratory sensation to the thoracic level, elevated immunoglobulin levels (IgG) in cerebrospinal fluid, but negative magnetic resonance imaging (MRI) of the brain and spine, is presented. A 57-year-old woman with spastic paraparesis and inability to walk was admitted to our neurological department. About four months before hospitalization, she started feeling numbness and tingling in the feet and lumbar spine area. Gradually, numbness and tingling ascended to the thoracic spine level Th7/8, and she developed weakness mostly in her legs. In the neurological exam she had spastic paraparesis. MRI of the brain, cervical and thoracic spine did not reveal any signal abnormality. Serological testing for SARS-CoV-2 was performed and results were highly positive IgG and IgM+IgA levels. The lumbar puncture finding confirmed the suspicion of immune-related complications after SARS-CoV-2 infection (intrathecal IgG synthesis). This case draws attention to spastic paraparesis or progressive MRI-negative myelitis after SARS-CoV-2 infection, which obviously has immune-mediated pathogenesis that happen in response to the virus or its antibodies. Similarities in spastic paraparesis after human T-lymphotropic virus (HTLV-1) or human immunodeficiency virus (HIV-1) and SARS-CoV-2 infections were observed. The patient had a good response to corticosteroid therapy and had good recovery.
Knj. 52-53(2020), 2020
Introduction: Anomalous innervations of the extremities are common and influence the interpretati... more Introduction: Anomalous innervations of the extremities are common and influence the interpretation of electrophysiologic studies in normal subjects and those with peripheral nerve lesions. The aim of this study was to describe the most common innervation anomalies in upper and lower extremities and to point out their clinical repercussions. Methods: Article has an analytical character and review of literature, including some personal articles. Results and Discussion: Double innervation and communications among nerves are causes of anomalies of innervation of the skin and muscles. The fact of communications of fibers among nerves is better called "nerve communication" than "nerve anastomosis". Anomalous innervations of the upper and lower extremities are, therefore, common and influence on the interpretation of neurophysiological parameters during electromyoneurography. Namely, in the course of an electrodiagnostic investigation of a peripheral nerve lesion, the examiner may be confronted with unexpected findings in contradiction with the clinical picture. In this review, a description is given of the most common innervation anomalies in upper and lower extremities: median to ulnar nerve communication (Martin-Gruber anastomosis); ulnar to median nerve communication (Marinacci anastomosis/MA); variations in the innervation of intrinsic muscles of the hand (Riche-Cannieu anastomosis; Berrettini anastomosis); accessory deep peroneal nerve; and tibial to peroneal nerve communication. Conclusion: As anomalous innervations of the extremities are common and influence the interpretation of electrophysiological studies in normal subjests and those with peripheral nerve lesions, detailed anatomical knowledge is essential for accurate interpretation of physical examination, electrophysiological findings, diagnosis, prognosis and reducing the risk of iatrogenic injuries during surgical procedures. If these variations are not given due regard, errors and other consequences will be inevitable.
Introduction: Carpal tunnel syndrome (CTS) is a collection of characteristic symptoms and signs t... more Introduction: Carpal tunnel syndrome (CTS) is a collection of characteristic symptoms and signs that occurs following compression of the median nerve within the carpal tunnel. The prevalence of electrophysiologically confirmed CTS in working populations is generally higher than in the general population. The aim was to present association between carpal tunnel syndrome and the excessive use of computer mouse and keyboard in young adult with presence of Martin-Gruber anastomosis. Case report: We presented the development of carpal tunnel syndrome in 17-year-old male, following the repetitive movement of the right wrist, due to excessive use of the computer mouse and keyboard. During the neurological examination, we found pronounced hypotrophy of the first interosseous dorsalis space (weakness of m. adductor pollicis), and mild hypotrophy of the thenar muscle. Nerve conduction velocities of n. ulnaris and n. medianus on the right hand were normal, but with prolonged value of distal la...
Acta Medica Saliniana, 2009
Generally, Arnold – Chiari malformation associated with syringomyelia is not rare. In this case r... more Generally, Arnold – Chiari malformation associated with syringomyelia is not rare. In this case report we present a 52 years old female patient with a history of neck-pain, low-back pain, pain in both arms as well as frequent numbness in the lateral regions of both arms. She also experienced walk disturbance and in her previous history she reports a car accident, twenty-eight years ago. She broke windshield with her forehead, but remained conscious at the time. At the time of admittance at the Department of Neurology, her neurological status was remarkable for cerebellar symptomatology (ataxia, positive Romberg-sign, «finger–nose» test which she did with tremor and was not able to perform «tandem-walk»), hypoestesia of the right side of the body, hyper-reflection of both arms and legs, bilaterally, more pronounced at the right side; right foot subclonus and spastic-ataxic walk. Neurological status could not be explained by previously performed tests: x-ray of cervical spine, lumbal ...
Acta Medica Saliniana, 2008
Introduction: Subarachnoid haemorrhage presents urgent state in neurology, with dramatic clinical... more Introduction: Subarachnoid haemorrhage presents urgent state in neurology, with dramatic clinical picture and high mortality. Aim of this study was to analize role of the risk factors in prognosis of patients with spontaneous subarachnoidal haemorrhage. Patients and Methods: It was analyzed 48 patients with spontaneous subarachnoidal haemorrhage which are cured on Neurological clinic in Tuzla in period from January 1. 2001 till December 31. 2002. Mean age of patients was 57.6 +/-12. years. Results: It was shown that the most frequent risk factors were hypertension (72.9%), heart diseases (54.1%) and smoking (39.6%). From all 48, 21 (43.7%) patients died. At survived patients, one month from begining of disease, cases. Survived had significant lower mean age (p= .009) and Hunt Hess score (p=0.001) at admission than the died. Patients with complexity find by computed tomography had bad prognosis. Conclusion: Older age of patients, higher number of risk factors, higher Hunt Hess score ...
European Neuropsychopharmacology, 2018
ANOVA (probe test and immunohistochemistry) followed by post hoc Fisher LSD test. In vitro: one-w... more ANOVA (probe test and immunohistochemistry) followed by post hoc Fisher LSD test. In vitro: one-way ANOVA followed by post hoc Tukey test. Results: Ts were severely impaired in various learning and memory parameters (po0.01) and had fewer new neurons (DCX + cells/100 mm) in the DG (-37%; po0.05) in comparison with Eu. Treatment with tideglusib did not improve either memory or neurogenesis. Similarly to adults, tideglusib-treated Ts pups underwent no neurogenesis increase, indicating that the lack of effects of tideglusib on neurogenesis is not age-dependent. Interestingly, vehicle alone (corn oil) improved behavior in adults and neurogenesis both in adults (+39%; po0.05) and pups (+ 26%; po0.001). The absence of these effects in Ts that received vehicle + tideglusib suggests that tideglusib counteracts the positive effects of the vehicle. In vitro experiments showed that i) a wide range of tideglusib concentrations (0.1-10.0mM) was unable to enhance neurogenesis of Ts NPCs; ii) exposure to OA or LA, the main components of corn oil, enhanced proliferation (+ 40-65%; po0.001); iii) the effect of OA and LA was abrogated by co-exposure to tideglusib. Conclusion: The finding that tideglusib does not improve neurogenesis and behavior indicates that it is not a suitable treatment for DS. The finding that the fatty acids present in the vehicle (OA and LA) have a pro-neurogenic effect suggests that agonists of fatty acid receptors may represent a good strategy to ameliorate brain development in individuals with DS.
Paediatrics Today, Jan 10, 2007
Cilj rada Otkriti moguće rizične faktore u novorođenčeta za nas tanak porođajne povrede brahijaln... more Cilj rada Otkriti moguće rizične faktore u novorođenčeta za nas tanak porođajne povrede brahijalnog pleksusa. Ispitanici i metode Studijom parova retrospektivno su analizira ni podaci o pojavi paralize pleksusa brahijalisa u porođaju 45503 novorođenčeta u periodu od 1. januara 1996. do 31. decembra 2004. u Klinici za ginekologiju i akušerstvo Univerzitetskokliničkog centra u Tuzli. U istraženoj populaciji otkriveno je 86 novorođenčadi s povredom pleksusa brahijalisa (ispitanici). Kon trolnu grupu sačinjava 86 novorođenčadi bez povrede pleksusa brahijalisa, izabranih nasumce kao slučajni uzorak iz iste popu lacije (kontrolna grupa). Ispitanici i kontrolna grupa uspoređeni su međusobno s obzirom na spol, trajanje gestacije, raspodjelu porođajnih težina, prezentaciju ploda pri porođaju, te s obzirom na Apgar-skor nakon prve i pete minute. Statistička značajnost rezultata procijenjena je 2 testom. Rezultati Između ispitanika i kontrolnih nije bilo razlike u spolu. Nađena je vrlo značajna razlika u distribuciji porođajnih težina: frekvencija ispitanika s porođajnim težinama od 4000 do 4599 grama, a osobito s težinama većim od 4500 g bila je vrlo značajno viša nego u istim težinskim skupinama kontrolnih. Razlika u učestalosti okcipitalne prezentacije u porodu u korist ispitanika nije bila statistički značajna. Među ispitanicima bio je znatno više nego u kontrolnih zastupljen niski Apgar-skor (7) nakon prve i pete minute. U 35 od 86 (42,5%) ispitanika utvrđena je udružena fraktura klavikule, a u po jednog, fraktura humerusa i rebara. Zaključak Najizraženiji rizični faktori su porođajna težina preko 4000 g i nizak Apgar-skor kao odraz traumatičnog porođaja, dok u našem istraživanju, karlični položaj ploda, kao rizični faktor nije statistički dokazan.
Paediatrics Today, May 21, 2006
Akutni diseminirani encefalomijelitis (ADEM) je u pravilu monofazična, imunološki uslovljena, bol... more Akutni diseminirani encefalomijelitis (ADEM) je u pravilu monofazična, imunološki uslovljena, bolest u kojoj se stvaraju multifokalne demijelinizirajuće lezije u centralnom nervnom sistemu (CNS). Međutim, ADEM se može manifestirati i multiplim relapsima bolesti sličnih multiploj sklerozi (MS). U pravilu je to bolest dječijeg doba (prije 10. godine života). ADEM može biti prva faza MS u oko 25% djece. Bolest nastaje akutno, a klinička slika zavisi od intenziteta procesa, odnosno zahvaćenih dijelova CNS-a. Odgovara infektivnom sindromu sa afekcijom meninga i različitih dijelova mozga i kičmene moždine. Prognoza je vrlo neizvjesna, sa letalnim završetkom kod oko 1/3 slučajeva. MS je hronična inflamatorna, nekontaginozna, progresivna multifokalna demijelinizirajuća, autoimuna bolest CNS (bijele mase mozga i kičmene moždine) koja se može manifestirati različitim neurološkim simptomima. Simptomi se najčešće (85-90%) javljaju u atacima (egzacerbacijama ili remisijama) ili sporo progresivno tokom vremena. Uzrok MS-e kao i patogeneza i danas nisu dovoljno poznati. Nasljedni faktori imaju važnu, vjerovatno predisponirajuću ulogu. Patogeneza MS uključuje inflamaciju, demijelinizaciju i gubitak aksona. MS se može pojaviti u bilo kom životnom dobu, a najčešće se javlja u trećoj ili četvrtoj deceniji. Pojava u djetinjstvu se procjenjuje na 3-5% slučajeva i smatra se da bar 2.5 do 5% od svih pacijenata sa MS prvu ataku bolesti doživi prije 16-og rođendana. Pojava prije desete godine je rijetkost i procjenjuje se da se javlja u 0.2% djece ovog uzrasta. Pretrage koje je potrebno napraviti prije nego se definitivno postavi dijagnoza ADEM-a i/ili MS-e su analiza cerebrospinalnog likvora, evocirani moždani potencijali, nuklearna magnetska rezonanca mozga i kičmene moždine. Također, potrebno je uraditi i nalaz kompjuterizirane tomografije mozga čije značenje nije u postavljanju dijagnoze MS-e, već u isključivanju postojanja drugih oštećenja mozga vaskularnog, tumorskog i drugog porijekla. Za sigurnu dijagnozu MS-a, danas su na snazi revidirani dijagnostički McDonaldovi kriterijumi iz 2001. godine, tzv. McDonaldovi kriterijumi 2005. U slučaju ADEM-a primjenjuje se antiinflamatorna (kortikosteroidi) i imunosupresivna terapija, u biti na isti način kao UVOD Mijelin je lipoproteinska membrana koja omotava aksone nervnih vlakana. Pripada mu 50% suhog ostatka bijele mase mozga. Sastav mijelina se unekoliko razlikuje u perifernom i centralnom nervnom sistemu. Čine ga holesterol, ADEM i MS u dječijoj dobi
Body dissatisfaction can be defined as a perceptive component of body image, as a difference betw... more Body dissatisfaction can be defined as a perceptive component of body image, as a difference between ideal body and a current body size. Body dissatisfaction is present not only in women who have eating disorders but in non-clinical population as well and to such extent that many American psychologists consider it a normative aspect of women's identity. The goal of this study was to investigate the presence of body dissatisfaction in non-clinical population of women in Bosnia and Herzegovina and to determine the differences in the level of body dissatisfaction between younger and mature women. It was predicted that body dissatisfaction would be present in women regardless of their age and that young women would demonstrate higher levels of body dissatisfaction than older women. 215 women were divided into young (≥25) and mature (≤40) groups and completed Stunkard's body figure rating scale and a demographic questionnaire. Results were consistent with the hypothesis. Women showed body dissatisfaction while age showed to be a significant factor. Socio-cultural perspective on body dissatisfaction was used in discussing the results.
Acta myologica : myopathies and cardiomyopathies : official journal of the Mediterranean Society of Myology / edited by the Gaetano Conte Academy for the study of striated muscle diseases, 2013
The accessory deep peroneal (ADPN) nerve has been regarded as an anomalous nerve derived from the... more The accessory deep peroneal (ADPN) nerve has been regarded as an anomalous nerve derived from the superficial peroneal nerve or its branch and supplies motor innervations for extensor digitorum brevis (EDB) and sensory innervations for the lateral part of the ankle and foot regions. The EDB is usually innervated exclusively by the deep peroneal nerve, a major branch of the the common peroneal nerve, however, in as many as 28% of patients (with same male/female frequency), one or both of the EDB muscles are (partially or exclusively) innervated by the ADPN nerve. This anomaly appears to be inherited in autosomal dominant fashion with incomplete gene penetrance. ADPN existence is of great clinical and surgical importance, and the aim of this study is to describe a very rare case of coexistence ADPN and anterior tarsal tunnel syndrome.
Bosnian journal of basic medical sciences / Udruženje basičnih mediciniskih znanosti = Association of Basic Medical Sciences, 2008
The objective of the study was to analyze the doppler sonography findings of vertebrobasilar circ... more The objective of the study was to analyze the doppler sonography findings of vertebrobasilar circulation (VB) in patients with Parkinson's disease. 40 patients were analyzed (25 men's and 15 women) with Parkinson's disease, average age was 61.9 years (SD=11.43), treated at the Clinic for Neurology in Tuzla. Device for doppler sonography was Multidop x 4. Doppler sonography findings of VB circulation were analyzed in order to computerized tomography (CT) findings of the brain (with or without ischemic lacunar lesions) and in order to presence of postural disturbances as one of dominant Parkinson's disease symptoms during actual hospitalization. Our results suggest that vertebrobasilar insufficiency is more frequent in patients with Parkinson's disease (no matter of type) and postural disturbances as a dominant symptom comparing to group of Parkinson's disease patients without postural disturbances. These results implicate the importance of doppler sonography f...
Bosnian journal of basic medical sciences / Udruženje basičnih mediciniskih znanosti = Association of Basic Medical Sciences, 2008
Intracerebral hemorrhage is the deadliest, most disabling and least treatable form of stroke desp... more Intracerebral hemorrhage is the deadliest, most disabling and least treatable form of stroke despite progression in medical science. The aim of the study was to analyze the frequency, risk factors, localization and 30-day prognosis in patients with intracerebral hemorrhage. We analyzed 352 patients with intracerebral hemorrhage (ICH) hospitalized at the Department of Neurology Tuzla during a three-year follow up. The following data were collected for all patients in a computerized database: age, sex, risk factors (hypertension, heart diseases, diabetes and smoking) and CT findings. Stroke severity was estimated with Scandinavian Stroke Scale, ICH topography was specified by CT, and outcome at 1st month after onset included information on vital status and disability (modified Rankin Scale, mRS). The most frequent risk factors were hypertension (84%), heart diseases (31%), cigarette smoking (28%) and diabetes mellitus (14%). The most frequent localization of ICH was multilobar (38%), ...
Bosnian journal of basic medical sciences / Udruženje basičnih mediciniskih znanosti = Association of Basic Medical Sciences, 2006
It was performed electroneurographic (ENG) studies with surface electrodes and examined nervus me... more It was performed electroneurographic (ENG) studies with surface electrodes and examined nervus medianus (NM) in 60 patients (38 females), average age of 50,28 years (X+/-SD=50,28+/-11), with clinical diagnosis of carpal tunnel syndrome (CTS) and at least one border or discrete abnormal value of conventional electrophysiological tests. It was also examined 57 healthy individuals (33 females) as control group, average age of 45,65 years (X+/-SD=45,65+/-9,68). The sensitivity and specificity of sensory-motor index (SMI), terminal latency index (TLI) and residual latency (RL) were calculated and compared. SMI is determinate by using following formula: distal distance (DD) (in cm)/distal motor latency (DML) (in ms) + sensory conduction velocity (SCV) (in m/s)/motor conduction velocity (MCV) (in m/s) of NM. SCV of NM was measured by antidromic technique in segment wrist-index finger and MCV of NM in forearm segment above wrist. SMI mean value of control group was 3,45 (X+/-SD=3,45+/-0,45)...
Bosnian journal of basic medical sciences / Udruzenje basicnih mediciniskih znanosti = Association of Basic Medical Sciences, 2002
A prospective case study was conducted in the Department of Occupational Medicine, Tuzla. The pur... more A prospective case study was conducted in the Department of Occupational Medicine, Tuzla. The purpose of this study was to indicate negative effects from occupational exposure to mercury on behavioural and mental health, memory and psychomotor function that was tested in 46 chloral-alkali plant workers (mean age was 38. 8+/- 5. 7 years; mean age of occupational history 16. 5+/- 6. 0 years). Data on toxicological monitoring on atomic absorption spectrometer, and data on mental health were collected, psychiatric and other subjective symptoms, and behavioural, psychomotor and memory function tested. The data were compared to control group, 32 healthy non exposed workers. The study was designed to assess blood and urine mercury levels and length of occupational exposure and investigate its relationships to effects on the mental health. The mean air mercury levels were 0.23 mg/m3, the mean blood mercury concentrations was 3. 6 mg/ dl and the mean urine mercury concentrations were 151.7 +...
Acta Medica Academica, 2012
The Journal of Maternal-Fetal & Neonatal Medicine, 2006
The 86 newborns with brachial plexus palsy have been recorded, the prevalence is 1.86 per 1000 li... more The 86 newborns with brachial plexus palsy have been recorded, the prevalence is 1.86 per 1000 live-born children. Analyzing maternal and neonatal factors, and the delivery pattern itself, it has been found that the highest risk-factors for brachial plexus injury are birth weight over 4000 grams, precipitous second stage of labor (<15 minutes), and vacuum-extractor assisted delivery of newborns. Brachial plexus palsy was more frequent when the newborns' mothers were overweight, with a body mass index ³29 kg/m 2. None of the parturient women, whose newborns were diagnosed with brachial plexus palsy, had a narrowed pelvis. Newborns, who were delivered vaginally, were not diagnosed to have a higher frequency of brachial plexus palsy compared to newborns who were delivered by Caesarean section, but newborns with vaginal breech delivery have had a higher incidence of brachial plexus palsy. Newborns, whose mothers were older than 35, had have brachial plexus palsy more frequently; statistically significant difference between primiparas and multiparas was not found. A total of 39 newborns (45.2%) were diagnosed to have a fracture of clavicle, which was the most frequently combined damage with brachial plexus injury. The 42 newborns (48.8%) had an Apgar score of £7 in the first minute after delivery, which indicates intrapartal distress of fetus and points to traumatic nature of these deliveries. Average birth weight of newborns with plexus brachialis damage was 3858±grames, which, for an average gestation age of 38.8±1,8 weeks of gestation, corresponds to eutrophic newborns. Both male and female newborns were diagnosed to have plexus brachialis equally and almost all deliveries (97.7%) started spontaneously. The majority of newborns were born early in the morning between 2-3 hours or afternoon between 14-15 hours.