Nuri Ozden - Academia.edu (original) (raw)

Papers by Nuri Ozden

Journal of the Pancreas, 2017

Skin manifestation associated with pancreatitis can have various presentations. Skin manifestatio... more Skin manifestation associated with pancreatitis can have various presentations. Skin manifestations such as Grey Turner sign or Cullen's sign are known and well documented findings of pancreatitis and carry significant prognostic value. However, livedo reticularis is a rare phenomenon in setting of pancreatitis. Here we report a case of 40 year old female who experiences recurrent episodes of livedo reticularis which is coupled with each bout of acute on chronic pancreatitis. In our patient, livedo reticularis disappears each time with resolution of acute episode of pancreatitis. The recurrent episodes of livedo reticularis from pancreatitis has been very rarely reported in literature. Recognizing skin manifestations in pancreatitis can help clinicians understand the severity and pathology of pancreatitis. Unlike Grey Turner sign or Cullen's sign, livedo reticularis has limited prognostic value, however, their presence deserve our attention. Further case reports and studies ...

Baylor University Medical Center Proceedings, 2020

American Journal of Gastroenterology, 2015

a 16x10x13 cm heterogeneous mass in ascending colon and multiple liver masses consistent with met... more a 16x10x13 cm heterogeneous mass in ascending colon and multiple liver masses consistent with metastases (Figure 1). Colonoscopy showed a necrotic friable mass in ascending colon nearly obstructing the lumen (Figure 2). Pathology revealed diff use large B cell lymphoma and immunohistochemical stains confi rmed a pattern favorable of a primary colonic B-cell lymphoma with positive CD20, PAX5, CD10 and BCL6 (Figure 3). Ki 67 was expressed as well in 85 to 95 % of the specimen. Biochemical profi le showed an elevated LDH, while CEA level was within normal limits. Flow cytometry blood test was negative and bone marrow biopsy ruled out any involvement. Th e patient refused surgery and was started on chemotherapy tailored to his lymphoma with favorable response on a PET scan done 6 months later. Primary malignant lymphoma of the colon remains a rare clinical entity specifi cally in immunocompetent individuals, accounting for a small proportion of both colorectal malignancies and GI lymphomas. Commonly it is a disease reported in association with disorders of altered immune status, infl ammatory bowel diseases and celiac disease. Historically, aggressive B-cell lymphomas have been the most common GI lymphomas reported in the literature. Most patients present with nonspecifi c symptoms which oft en lead to delays in diagnosis and advanced stage at presentation, as demonstrated in our patient who presented with metastatic disease to the liver. Treatment usually involves chemotherapy, radiation, surgery or a combination of these, in contrast to colonic adecarcinoma where surgery is the mainstay of therapy. In aggressive lymphomas, resection serves to control local disease to prevent obstruction and perforation, however the defi nitive management remains to be CHOP or other polychemotherapies. Increased awareness of this disease is of utmost importance to avoid delays in diagnosis and tailor further management accordingly, in order to prevent complications.

American Journal of Gastroenterology, 2016

Case reports in gastroenterology

Colonic postanastomotic strictures occur in 1.5-8% of patients following colorectal surgery. Trad... more Colonic postanastomotic strictures occur in 1.5-8% of patients following colorectal surgery. Traditionally, colonic strictures were treated by multiple modalities including endoscopic dilatation. Self-expanding metal stents (SEMS) have been indicated in the management of benign colonic strictures; however, there are limited available data with regard to their efficacy. We present the case of a 68-year-old male who had perforated sigmoid diverticulitis followed by Hartmann's procedure with eventual reanastomosis 6 months later. He subsequently developed benign colonic stricture, which was treated with a metal stent. SEMS are associated with a low mortality rate and are appropriate in treating acute colonic obstruction as a result of benign stricture in the setting of postanastomosis.

Clinics in geriatric medicine, 2007

Intestinal ischemia is a relatively common disorder in the elderly and, if not treated promptly, ... more Intestinal ischemia is a relatively common disorder in the elderly and, if not treated promptly, still carries a high morbidity and mortality rate. High degree of clinical suspicion is of paramount importance in diagnosis, because there is no specific laboratory test available and physical examination findings may be subtle. Once the diagnosis is made, management relies on early resuscitation, identification, and treatment of the predisposing conditions, along with careful planning of the therapeutic invasive interventions, which altogether may help reduce the mortality and morbidity associated with this condition.

Medical science monitor : international medical journal of experimental and clinical research, 2002

1. Med Sci Monit. 2002 Dec;8(12):LE51-2. How hemolysis causes acute pancreatitis. Saruc M, Ozden ... more 1. Med Sci Monit. 2002 Dec;8(12):LE51-2. How hemolysis causes acute pancreatitis. Saruc M, Ozden N, Yuceyar H. PMID: 12546022 [PubMed - indexed for MEDLINE]. Publication Types: Letter. Mesh Terms: Acute Disease; Animals; ...

Medical science monitor : international medical journal of experimental and clinical research, 2002

We aimed to clarify the outcome of perendoscopic prophylactic injection of sclerosing agent in Fo... more We aimed to clarify the outcome of perendoscopic prophylactic injection of sclerosing agent in Forrest's II ulcers. Patients with upper gastrointestinal bleeding in last 6 hours were performed emergency endoscopy and were enrolled. The patients in group-1 were performed prophylactic injection therapy with 1% aethoxysclerol and then given medical treatment with intravenous 40 mg omeprazole twice a day and somatostatin infusion at the dose of 6 mg/day during 3 days. Group-2 patients were only given medical treatment with same agents and at same doses without having any perendoscopic therapy. There were 32 patients in group-1 and 20 in group-2. In emergency endoscopy, 20 (62.5%) patients had IIa ulcers and 12 (37.5%) patients had IIb ulcers in group-1. These patients underwent prophylactic perendoscopic hemostasis by 1% aethoxysclerol in addition to medical treatment. Early rebleeding occurred in 9 (28.1%) patients of group-1 and 3 (15%) in group-2 (p<0.001). At the endoscopic c...

International Journal of Gastrointestinal Cancer, 2004

Journal of Hepatology, 2003

Gastrointestinal Endoscopy, 2012

The gastric mucosa is relatively sensitive to the effects of radiation, which can be intensified ... more The gastric mucosa is relatively sensitive to the effects of radiation, which can be intensified by the use of certain chemotherapeutic agents such as fluorouracil. The case reported here demonstrates that where HBOT is unsuccessful, alternative multimodality endoscopic therapy including RFA and APC can be considered to avoid the need for ongoing transfusion and the possible need for secondary resection. In this case, RFA was particularly advantageous because of the large mucosal surface area requiring Figure 3. The gastric conduit after the completion of endoscopic therapy. Note the absence of residual telangectasias.

Gastrointestinal Endoscopy, 2009

Gastrointestinal Endoscopy, 2010

Gastroenterology Nursing, 2003

Gastroenterology, 2003

Gastroenterology, Volume 124, Issue 4, Pages A738, April 2003, Authors:Halim O. Muslu; Nuri Ozden... more Gastroenterology, Volume 124, Issue 4, Pages A738, April 2003, Authors:Halim O. Muslu; Nuri Ozden; Murat Saruc; Kamran Safdar; Douglas Meyer; Marzia Montalbano; Guy W. Neff; Andreas Tzakis; Christopher B. O'Brien; Eugene R. Schiff. ...