Patrice Hubert - Academia.edu (original) (raw)

Papers by Patrice Hubert

Research paper thumbnail of Feasibility of a Theory-Based, Online Tailored Message Program to Motivate Healthier Behaviors in College Women

Nutrients

We aimed to test the feasibility of an online survey and tailored message program in young women.... more We aimed to test the feasibility of an online survey and tailored message program in young women. Recruited from college campuses, women (n = 189) completed an online survey assessing preference for and behaviors toward diet and physical activity as well as theory-based influencers of these behaviors (knowledge/information, motivation, and confidence). Health messages were tailored to the participant’s survey responses and learning style to address misconceptions and motivate or reinforce healthy physical activity and dietary behaviors. Most women reported the survey as relevant (92%) and useful for reflecting on their health (83%), with survey responses variable in level of nutrition and physical activity knowledge, motivation, and confidence. Each woman received four tailored messages—most reported the messages as relevant (80%) and learning new information (60%). Across all messages, nearly half of the participants (~48%) reported willingness to try or maintain healthier behavior...

Research paper thumbnail of Black currant extract attenuates ovariectomy‐induced bone loss in mice (1027.7)

The FASEB Journal, Apr 1, 2014

Bone remodeling is orchestrated by osteoblasts and osteoclasts in response to changes in redox st... more Bone remodeling is orchestrated by osteoblasts and osteoclasts in response to changes in redox status, inflammatory cytokines, and hormones. Several animal and cell studies indicate that black currant (BC) exerts antioxidative and anti-inflammatory properties, which could potentially improve bone mass. This study was aimed to evaluate the effect of BC on bone mass and structure in a mouse model of ovarian hormone deficiency. 14-wk old C57BL/6J mice were ovariectomized (OVX) or sham operated. The OVX mice were divided into two groups; OVX fed a basal diet (control) and OVX fed the same diet but with 1% BC extract (provided by the Just The Berries LTD), and sacrificed at 4, 8, and 12 wk. Femoral bone mineral density (BMD) and trabecular bone volume (TBV) by DXA and micro-CT and serum bone markers were determined. OVX significantly reduced BMD and TBV (p<0.05) at all time points. At 8 and 12 wk, BC supplementation attenuated OVX-induced BMD and TBV. OVX and BC treatment did not alter serum biomarkers of bone...

Research paper thumbnail of Chemosensory function, dietary preference and dietary behaviors from pre- to 6-months post-bariatric surgery: A pilot study

Surgery for Obesity and Related Diseases, 2017

Research paper thumbnail of Can Assessing Physical Activity Liking Identify Opportunities to Promote Physical Activity Engagement and Healthy Dietary Behaviors?

Nutrients, 2021

Improving our understanding of what physical activities are enjoyed and the factors that are asso... more Improving our understanding of what physical activities are enjoyed and the factors that are associated with physical activity liking can promote participation in regular physical activity. We aimed to study physical activity (PA) liking in college women by modelling interactions between body size perception and dietary behaviors on PA liking, and by examining discrepancies between PA liking versus engagement on body size perception and dietary behaviors. Women (n = 251; 74% white) utilized an online survey to report their level of liking for PA types (scored into a PA liking index) and frequency of PA participation. They also reported their perceived body size, level of dietary restraint, and frequency of consuming foods (scored into a diet quality index). In multivariate analyses, a greater perceived body size was directly associated with lower PA liking and indirectly through greater dietary restraint but lower diet quality. Healthiest dietary behaviors were reported by women who...

Research paper thumbnail of A qualitative assessment of US Black and Latino adolescents’ attitudes about targeted marketing of unhealthy food and beverages

Journal of Children and Media, 2019

Appiah (2019) A qualitative assessment of US Black and Latino adolescents' attitudes about target... more Appiah (2019) A qualitative assessment of US Black and Latino adolescents' attitudes about targeted marketing of unhealthy food and beverages,

Research paper thumbnail of Evaluating Taste Preferences and Dietary Quality with a Simple Liking Survey: Application in Bariatric Treatment Settings

Bariatric Surgical Practice and Patient Care, 2019

Background: Feasible and useful methods are needed to screen for taste preferences and dietary be... more Background: Feasible and useful methods are needed to screen for taste preferences and dietary behaviors in obesity treatment settings. Aim: We examined the reliability and validity of a brief liki...

Research paper thumbnail of Associations between Weight Loss, Food Likes, Dietary Behaviors, and Chemosensory Function in Bariatric Surgery: A Case-Control Analysis in Women

Nutrients, 2019

We tested the hypothesis that successful weight loss post-bariatric surgery would be associated w... more We tested the hypothesis that successful weight loss post-bariatric surgery would be associated with healthier chemosensory function, food likes, and dietary behaviors than either unsuccessful weight loss or pre-surgery morbid obesity. In a case-control design, pre-surgical women with morbid obesity (n = 49) were compared with those 1-year post-surgery (24 Roux-en-Y Bypass, 24 Sleeve Gastrectomy) and defined by excess or percent weight loss as successful/unsuccessful. For self-reported smell/taste perception, more post-surgery than pre-surgery reported improved/distorted perception, especially if weight loss successful. Measured taste function (perceived quinine and NaCl intensity) was lower among weight loss unsuccessful versus pre-surgery patients, yet a genetic variation in taste probe (propylthiouracil bitterness) matched expected frequencies without significant pre/post-surgery difference. Regarding survey-reported liking, higher diet quality was seen in the weight loss success...

Research paper thumbnail of Aronia berry polyphenol consumption reduces plasma total and low-density lipoprotein cholesterol in former smokers without lowering biomarkers of inflammation and oxidative stress: a randomized controlled trial

Nutrition research (New York, N.Y.), 2017

Former smokers are at increased risk for cardiovascular disease. We hypothesized that dietary aro... more Former smokers are at increased risk for cardiovascular disease. We hypothesized that dietary aronia polyphenols would reduce biomarkers of cardiovascular disease risk, inflammation, and oxidative stress in former smokers. We also determined the extent these effects were associated with polyphenol bioavailability. A 12-week, randomized, placebo-controlled trial was conducted in 49 healthy adult former smokers (n = 24/placebo, n = 25/aronia) to evaluate if daily consumption of 500 mg aronia extract modulated plasma lipids, blood pressure, biomarkers of inflammation and oxidative stress, and lipid transport genes of peripheral blood mononuclear cells. The primary outcome was change in low-density lipoprotein cholesterol (LDL-C) from baseline, and multivariate correlation analysis was performed to determine if changes in lipids were associated with urinary polyphenol excretion. Aronia consumption reduced fasting plasma total cholesterol by 8% (P = .0140), LDL-C by 11% (P = .0285), and ...

Research paper thumbnail of Validation of Analytical Methods for Plasma Total Antioxidant Capacity by Comparing with Urinary 8-isoprostane Level

Journal of microbiology and biotechnology, Jan 25, 2016

Although several analytical methods for measuring total antioxidant capacity (TAC) have been appl... more Although several analytical methods for measuring total antioxidant capacity (TAC) have been applied to biological samples, there were often dissimilar results due to the different principles of methods applied. Thus, this study aimed to validate four conventional analytical methods for measuring plasma TAC including ABTS assay, DPPH assay, FRAP assay, and ORAC assay by comparing with urinary 8-isoprostane concentration. In addition, TAC results were also compared with erythrocyte antioxidant enzyme activities including superoxide dismutase (SOD), catalase, and glutathione peroxidase. Plasma TAC measure by ABTS assay was strongly correlated with the result by FRAP assay. Plasma TAC by FRAP and ORAC assays were negatively correlated with erythrocyte SOD activity. The agreement between four TAC methods and 8-isoprostane was determined using 95% prediction limits of linear regression expressed as mean of 8-isoprostane ± 95% prediction limits. The ABTS method better agreed with 8-isopro...

Research paper thumbnail of Anthocyanin-Rich Blackcurrant Extract Attenuates Ovariectomy-Induced Bone Loss in Mice

Journal of medicinal food, 2016

Although several animal and cell studies have indicated that blackcurrant anthocyanins exert anti... more Although several animal and cell studies have indicated that blackcurrant anthocyanins exert antioxidative and anti-inflammatory properties, which could potentially improve bone mass, the effect of blackcurrant on bone health has not been reported yet. Thus, this study was aimed to evaluate the effect of blackcurrant anthocyanins on bone mass in an estrogen deficiency mouse model. Fourteen-week-old C57BL/6J mice (n = 54) were ovariectomized or sham operated. The ovariectomized mice were divided into two groups, basal diet (OVX) or basal diet containing 1% anthocyanin-rich blackcurrant extract (OVX+BC), and sacrificed at 4, 8, and 12 weeks. Femoral bone mineral density (BMD) and trabecular bone volume by dual-energy X-ray absorptiometry and micro-computed tomography, respectively, and serum bone markers were measured. Ovariectomy significantly reduced BMD and trabecular bone volume at all time points (P < .05). Blackcurrant supplementation attenuated ovariectomy-induced bone loss ...

Research paper thumbnail of Dietary Polyphenols, Berries, and Age-Related Bone Loss: A Review Based on Human, Animal, and Cell Studies

Antioxidants, 2014

Bone loss during aging has become an increasing public health concern as average life expectancy ... more Bone loss during aging has become an increasing public health concern as average life expectancy has increased. One of the most prevalent forms of age-related bone disease today is osteoporosis in which the body slows down bone formation and existing bone is increasingly being resorbed by the body to maintain the calcium balance. Some causes of this bone loss can be attributed to dysregulation of osteoblast and osteoclast activity mediated by increased oxidative stress through the aging process. Due to certain serious adverse effects of the currently available therapeutic agents that limit their efficacy, complementary and alternative medicine (CAM) has garnered interest as a natural means for the prevention of this debilitating disease. Natural antioxidant supplementation, a type of CAM, has been researched to aid in reducing bone loss caused by oxidative stress. Naturally occurring polyphenols, such as anthocyanins rich in berries, are known to have anti-oxidative properties. Several studies have been reviewed to determine the impact polyphenol intake-particularly that of berries-has on bone health. Studies reveal a positive association of high berry intake and higher bone mass, implicating berries as possible inexpensive alternatives in reducing the risk of age related bone loss.

Research paper thumbnail of Feasibility of a Theory-Based, Online Tailored Message Program to Motivate Healthier Behaviors in College Women

Nutrients

We aimed to test the feasibility of an online survey and tailored message program in young women.... more We aimed to test the feasibility of an online survey and tailored message program in young women. Recruited from college campuses, women (n = 189) completed an online survey assessing preference for and behaviors toward diet and physical activity as well as theory-based influencers of these behaviors (knowledge/information, motivation, and confidence). Health messages were tailored to the participant’s survey responses and learning style to address misconceptions and motivate or reinforce healthy physical activity and dietary behaviors. Most women reported the survey as relevant (92%) and useful for reflecting on their health (83%), with survey responses variable in level of nutrition and physical activity knowledge, motivation, and confidence. Each woman received four tailored messages—most reported the messages as relevant (80%) and learning new information (60%). Across all messages, nearly half of the participants (~48%) reported willingness to try or maintain healthier behavior...

Research paper thumbnail of Black currant extract attenuates ovariectomy‐induced bone loss in mice (1027.7)

The FASEB Journal, Apr 1, 2014

Bone remodeling is orchestrated by osteoblasts and osteoclasts in response to changes in redox st... more Bone remodeling is orchestrated by osteoblasts and osteoclasts in response to changes in redox status, inflammatory cytokines, and hormones. Several animal and cell studies indicate that black currant (BC) exerts antioxidative and anti-inflammatory properties, which could potentially improve bone mass. This study was aimed to evaluate the effect of BC on bone mass and structure in a mouse model of ovarian hormone deficiency. 14-wk old C57BL/6J mice were ovariectomized (OVX) or sham operated. The OVX mice were divided into two groups; OVX fed a basal diet (control) and OVX fed the same diet but with 1% BC extract (provided by the Just The Berries LTD), and sacrificed at 4, 8, and 12 wk. Femoral bone mineral density (BMD) and trabecular bone volume (TBV) by DXA and micro-CT and serum bone markers were determined. OVX significantly reduced BMD and TBV (p<0.05) at all time points. At 8 and 12 wk, BC supplementation attenuated OVX-induced BMD and TBV. OVX and BC treatment did not alter serum biomarkers of bone...

Research paper thumbnail of Chemosensory function, dietary preference and dietary behaviors from pre- to 6-months post-bariatric surgery: A pilot study

Surgery for Obesity and Related Diseases, 2017

Research paper thumbnail of Can Assessing Physical Activity Liking Identify Opportunities to Promote Physical Activity Engagement and Healthy Dietary Behaviors?

Nutrients, 2021

Improving our understanding of what physical activities are enjoyed and the factors that are asso... more Improving our understanding of what physical activities are enjoyed and the factors that are associated with physical activity liking can promote participation in regular physical activity. We aimed to study physical activity (PA) liking in college women by modelling interactions between body size perception and dietary behaviors on PA liking, and by examining discrepancies between PA liking versus engagement on body size perception and dietary behaviors. Women (n = 251; 74% white) utilized an online survey to report their level of liking for PA types (scored into a PA liking index) and frequency of PA participation. They also reported their perceived body size, level of dietary restraint, and frequency of consuming foods (scored into a diet quality index). In multivariate analyses, a greater perceived body size was directly associated with lower PA liking and indirectly through greater dietary restraint but lower diet quality. Healthiest dietary behaviors were reported by women who...

Research paper thumbnail of A qualitative assessment of US Black and Latino adolescents’ attitudes about targeted marketing of unhealthy food and beverages

Journal of Children and Media, 2019

Appiah (2019) A qualitative assessment of US Black and Latino adolescents' attitudes about target... more Appiah (2019) A qualitative assessment of US Black and Latino adolescents' attitudes about targeted marketing of unhealthy food and beverages,

Research paper thumbnail of Evaluating Taste Preferences and Dietary Quality with a Simple Liking Survey: Application in Bariatric Treatment Settings

Bariatric Surgical Practice and Patient Care, 2019

Background: Feasible and useful methods are needed to screen for taste preferences and dietary be... more Background: Feasible and useful methods are needed to screen for taste preferences and dietary behaviors in obesity treatment settings. Aim: We examined the reliability and validity of a brief liki...

Research paper thumbnail of Associations between Weight Loss, Food Likes, Dietary Behaviors, and Chemosensory Function in Bariatric Surgery: A Case-Control Analysis in Women

Nutrients, 2019

We tested the hypothesis that successful weight loss post-bariatric surgery would be associated w... more We tested the hypothesis that successful weight loss post-bariatric surgery would be associated with healthier chemosensory function, food likes, and dietary behaviors than either unsuccessful weight loss or pre-surgery morbid obesity. In a case-control design, pre-surgical women with morbid obesity (n = 49) were compared with those 1-year post-surgery (24 Roux-en-Y Bypass, 24 Sleeve Gastrectomy) and defined by excess or percent weight loss as successful/unsuccessful. For self-reported smell/taste perception, more post-surgery than pre-surgery reported improved/distorted perception, especially if weight loss successful. Measured taste function (perceived quinine and NaCl intensity) was lower among weight loss unsuccessful versus pre-surgery patients, yet a genetic variation in taste probe (propylthiouracil bitterness) matched expected frequencies without significant pre/post-surgery difference. Regarding survey-reported liking, higher diet quality was seen in the weight loss success...

Research paper thumbnail of Aronia berry polyphenol consumption reduces plasma total and low-density lipoprotein cholesterol in former smokers without lowering biomarkers of inflammation and oxidative stress: a randomized controlled trial

Nutrition research (New York, N.Y.), 2017

Former smokers are at increased risk for cardiovascular disease. We hypothesized that dietary aro... more Former smokers are at increased risk for cardiovascular disease. We hypothesized that dietary aronia polyphenols would reduce biomarkers of cardiovascular disease risk, inflammation, and oxidative stress in former smokers. We also determined the extent these effects were associated with polyphenol bioavailability. A 12-week, randomized, placebo-controlled trial was conducted in 49 healthy adult former smokers (n = 24/placebo, n = 25/aronia) to evaluate if daily consumption of 500 mg aronia extract modulated plasma lipids, blood pressure, biomarkers of inflammation and oxidative stress, and lipid transport genes of peripheral blood mononuclear cells. The primary outcome was change in low-density lipoprotein cholesterol (LDL-C) from baseline, and multivariate correlation analysis was performed to determine if changes in lipids were associated with urinary polyphenol excretion. Aronia consumption reduced fasting plasma total cholesterol by 8% (P = .0140), LDL-C by 11% (P = .0285), and ...

Research paper thumbnail of Validation of Analytical Methods for Plasma Total Antioxidant Capacity by Comparing with Urinary 8-isoprostane Level

Journal of microbiology and biotechnology, Jan 25, 2016

Although several analytical methods for measuring total antioxidant capacity (TAC) have been appl... more Although several analytical methods for measuring total antioxidant capacity (TAC) have been applied to biological samples, there were often dissimilar results due to the different principles of methods applied. Thus, this study aimed to validate four conventional analytical methods for measuring plasma TAC including ABTS assay, DPPH assay, FRAP assay, and ORAC assay by comparing with urinary 8-isoprostane concentration. In addition, TAC results were also compared with erythrocyte antioxidant enzyme activities including superoxide dismutase (SOD), catalase, and glutathione peroxidase. Plasma TAC measure by ABTS assay was strongly correlated with the result by FRAP assay. Plasma TAC by FRAP and ORAC assays were negatively correlated with erythrocyte SOD activity. The agreement between four TAC methods and 8-isoprostane was determined using 95% prediction limits of linear regression expressed as mean of 8-isoprostane ± 95% prediction limits. The ABTS method better agreed with 8-isopro...

Research paper thumbnail of Anthocyanin-Rich Blackcurrant Extract Attenuates Ovariectomy-Induced Bone Loss in Mice

Journal of medicinal food, 2016

Although several animal and cell studies have indicated that blackcurrant anthocyanins exert anti... more Although several animal and cell studies have indicated that blackcurrant anthocyanins exert antioxidative and anti-inflammatory properties, which could potentially improve bone mass, the effect of blackcurrant on bone health has not been reported yet. Thus, this study was aimed to evaluate the effect of blackcurrant anthocyanins on bone mass in an estrogen deficiency mouse model. Fourteen-week-old C57BL/6J mice (n = 54) were ovariectomized or sham operated. The ovariectomized mice were divided into two groups, basal diet (OVX) or basal diet containing 1% anthocyanin-rich blackcurrant extract (OVX+BC), and sacrificed at 4, 8, and 12 weeks. Femoral bone mineral density (BMD) and trabecular bone volume by dual-energy X-ray absorptiometry and micro-computed tomography, respectively, and serum bone markers were measured. Ovariectomy significantly reduced BMD and trabecular bone volume at all time points (P < .05). Blackcurrant supplementation attenuated ovariectomy-induced bone loss ...

Research paper thumbnail of Dietary Polyphenols, Berries, and Age-Related Bone Loss: A Review Based on Human, Animal, and Cell Studies

Antioxidants, 2014

Bone loss during aging has become an increasing public health concern as average life expectancy ... more Bone loss during aging has become an increasing public health concern as average life expectancy has increased. One of the most prevalent forms of age-related bone disease today is osteoporosis in which the body slows down bone formation and existing bone is increasingly being resorbed by the body to maintain the calcium balance. Some causes of this bone loss can be attributed to dysregulation of osteoblast and osteoclast activity mediated by increased oxidative stress through the aging process. Due to certain serious adverse effects of the currently available therapeutic agents that limit their efficacy, complementary and alternative medicine (CAM) has garnered interest as a natural means for the prevention of this debilitating disease. Natural antioxidant supplementation, a type of CAM, has been researched to aid in reducing bone loss caused by oxidative stress. Naturally occurring polyphenols, such as anthocyanins rich in berries, are known to have anti-oxidative properties. Several studies have been reviewed to determine the impact polyphenol intake-particularly that of berries-has on bone health. Studies reveal a positive association of high berry intake and higher bone mass, implicating berries as possible inexpensive alternatives in reducing the risk of age related bone loss.