Pattawut Manapongpun - Academia.edu (original) (raw)
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AICCON - Associazione Italiana per la Promozione della Cultura della Cooperazione e del Non Profit
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Papers by Pattawut Manapongpun
Scientific Reports, Jul 26, 2019
A non-enzymatic glucose sensor enabled by bioelectronic pH control Xenofon strakosas, John selber... more A non-enzymatic glucose sensor enabled by bioelectronic pH control Xenofon strakosas, John selberg, pattawong pansodtee, Nebyu Yonas, pattawut Manapongpun, Mircea teodorescu & Marco Rolandi Continuous glucose monitoring from sweat and tears can improve the quality of life of diabetic patients and provide data for more accurate diagnosis and treatment. Current continuous glucose sensors use enzymes with a one-to-two week lifespan, which forces periodic replacement. Metal oxide sensors are an alternative to enzymatic sensors with a longer lifetime. However, metal oxide sensors do not operate in sweat and tears because they function at high pH (pH > 10), and sweat and tears are neutral (pH = 7). Here, we introduce a non-enzymatic metal oxide glucose sensor that functions in neutral fluids by electronically inducing a reversible and localized pH change. We demonstrate glucose monitoring at physiologically relevant levels in neutral fluids mimicking sweat, and wireless communication with a personal computer via an integrated circuit board.
Scientific Reports, Jul 26, 2019
A non-enzymatic glucose sensor enabled by bioelectronic pH control Xenofon strakosas, John selber... more A non-enzymatic glucose sensor enabled by bioelectronic pH control Xenofon strakosas, John selberg, pattawong pansodtee, Nebyu Yonas, pattawut Manapongpun, Mircea teodorescu & Marco Rolandi Continuous glucose monitoring from sweat and tears can improve the quality of life of diabetic patients and provide data for more accurate diagnosis and treatment. Current continuous glucose sensors use enzymes with a one-to-two week lifespan, which forces periodic replacement. Metal oxide sensors are an alternative to enzymatic sensors with a longer lifetime. However, metal oxide sensors do not operate in sweat and tears because they function at high pH (pH > 10), and sweat and tears are neutral (pH = 7). Here, we introduce a non-enzymatic metal oxide glucose sensor that functions in neutral fluids by electronically inducing a reversible and localized pH change. We demonstrate glucose monitoring at physiologically relevant levels in neutral fluids mimicking sweat, and wireless communication with a personal computer via an integrated circuit board.