Paula Morón Muñoz - Academia.edu (original) (raw)

Papers by Paula Morón Muñoz

Research paper thumbnail of Abscisic Acid Synthesis and Signaling during the Ripening of Raspberry (Rubus idaeus ‘Heritage’) Fruit

Plants

The raspberry (Rubus idaeus L.) fruit is characterized by its richness in functional molecules an... more The raspberry (Rubus idaeus L.) fruit is characterized by its richness in functional molecules and high nutritional value, but the high rate of fruit softening limits its quality during postharvest. Raspberry drupelets have a particular ripening regulation, depending partially on the effect of ethylene produced from the receptacle. However, the possible role of abscisic acid (ABA) in the modulation of quality parameters during the ripening of raspberry is unclear. This study characterized the fruit quality-associated parameters and hormonal contents during fruit development in two seasons. The quality parameters showed typical changes during ripening: a drastic loss of firmness, increase in soluble solids content, loss of acidity, and turning to a red color from the large green stage to fully ripe fruit in both seasons. A significant increase in the ABA content was observed during the ripening of drupelets and receptacles, with the higher content in the receptacle of ripe and overri...

Research paper thumbnail of Modeling Objects with Uncertain Behaviors

The Journal of Object Technology

Research paper thumbnail of How alike are my physical and digital twins?

Proceedings of the 25th International Conference on Model Driven Engineering Languages and Systems: Companion Proceedings

A digital twin is a virtual replica of a system defined at a certain level of fidelity, and synch... more A digital twin is a virtual replica of a system defined at a certain level of fidelity, and synchronized at a specific frequency. Digital twins are often used to replicate physical systems whose simulations are usually computationally costly. One of the solutions proposed in the literature to this problem is to define a hierarchy of multi-fidelity digital twins, where we use one twin or another depending on the specific purpose. However, one of the challenges of this proposal is the need to determine whether these twins are equivalent to each other and the physical system according to their purpose. In this work, we explore different methods to measure this equivalence by analyzing the state and behavior of the twins using high-level software models. CCS CONCEPTS • Software and its engineering → Operational analysis.

Research paper thumbnail of Using trace alignments for measuring the similarity between a physical and its digital twin

Proceedings of the 25th International Conference on Model Driven Engineering Languages and Systems: Companion Proceedings

Research paper thumbnail of Measuring the fidelity of digital twin systems

Proceedings of the 25th International Conference on Model Driven Engineering Languages and Systems: Companion Proceedings

A digital twin is a virtual replica of a system at a certain level of fidelity, synchronized at a... more A digital twin is a virtual replica of a system at a certain level of fidelity, synchronized at a specific frequency. Digital twins often replicate physical systems whose simulations are usually computationally costly. One of the solutions to this problem proposed in the literature is to define a hierarchy of multi-fidelity digital twins, where we use one twin or another depending on the specific purpose. However, one of the challenges of this proposal is the need to determine whether the different twins are equivalent to each other and the physical system. In this thesis, we explore different methods to measure this equivalence by analyzing the state and behavior of the twins with the aid of high-level software models. CCS CONCEPTS • Software and its engineering → Operational analysis.

Research paper thumbnail of Revisiting Fault Localization Techniques for Model Transformations: Towards A Hybrid Approach

The Journal of Object Technology

Research paper thumbnail of PbSRT1 and PbSRT2 regulate pear growth and ripening yet displaying a species-specific regulation in comparison to other Rosaceae spp

Research paper thumbnail of Determinación del sexo en cráneo y mandíbula en una muestra contemporánea de Medellín

Maguaré, 2005

Se estudiaron 21 dimensiones en craneo y mandibula para analizar el dimorfi smo sexual en una mue... more Se estudiaron 21 dimensiones en craneo y mandibula para analizar el dimorfi smo sexual en una muestra de poblacion contemporanea de Medellin, utilizando con fi nes comparativos tres metodos diferentes de estima del dimorfi smo sexual. La magnitud de este, estimada mediante la t de Student proporciono un numero ligeramente mayor de dimensiones dimorficas que el test de Kolmogorov-Smirnov (KS) para muestras independientes. Sin embargo, la t de Student mostro resultados similares a los del test de la F (ANOVA) aplicado por Rosique et al. (2004) en un estudio precedente. El calculo del MDI (Mean Distance Index) fue superior al 5% en las dimensiones diagnosticadas simultaneamente como dimorfi cas por los tres test de signifi cacion (t, F y KS). El test de Kolmogorov-Smirnov se evidencio como recomendable para estimar el dimorfi smo sexual, frente a los otros tests, para varias dimensiones. Tanto el analisis univariado como el analisis discriminante evidenciaron un mayor poder diagnostico...

Research paper thumbnail of Transient photoinhibition and photo-oxidative stress as an integral part of stress acclimation and plant development in a dioecious tree adapted to Mediterranean ecosystems

Tree Physiology, 2021

Mastic trees (Pistacia lentiscus L.) are dioecious perennial plants that are highly adapted to Me... more Mastic trees (Pistacia lentiscus L.) are dioecious perennial plants that are highly adapted to Mediterranean climates but display a high sensitivity to winter periods. In order to understand how sex, leaf phenology and ecological context could condition sensitivity to winter and associated mechanisms to acclimate to these conditions, photoinhibition and photo-oxidative stress markers were examined in mastic trees (P. lentiscus) from a natural population growing in the Garraf Natural Park for a consecutive 12-month period (seasonal study), as well as in three populations naturally growing in the Montseny Natural Park, including the highest altitudes described for this species, during winter (altitudinal study). Results from these studies indicate that both the winter period and higher elevation influenced the degree of photoinhibition, but this was not conditioned by sex. In fact, winter photoinhibition occurred transiently even though it was accompanied by chlorophyll loss and malon...

Research paper thumbnail of Extending OCL with Subjective Logic

The Journal of Object Technology, 2020

Research paper thumbnail of Democracy against Parties? Party System Deinstitutionalization in Colombia

Journal of Politics in Latin America, 2011

This article argues that in Colombia, decentralization and electoral reforms adopted in the late ... more This article argues that in Colombia, decentralization and electoral reforms adopted in the late 1980s and in the 1991 Constitution – designed to improve democratic quality – brought about a gradual deinstitutionalization of this country's traditional party system as an unintended consequence. Building upon resource-based theories of party configuration, we contend that in developing countries, where resources are usually crucial for party aggregation, “democratizing” reforms designed to distribute power and resources in the political system can reduce local candidates’ incentives to join and remain loyal to political parties, particularly when those parties’ reputations are weak. In Colombia, these reforms (i) reduced the power of intermediate-level party leaders over the distribution of selective incentives, making these leaders less important for local politicians, and (ii) gave more political and financial autonomy to local candidates, reducing their need to join parties in ...

Research paper thumbnail of Vitiligo type cutaneous manifestation of chronic graft-versus-host disease. Case report

Revista chilena de pediatria, 2018

Graft-versus-host disease (GVHD) is caused by a pathologic and destructive response of the organi... more Graft-versus-host disease (GVHD) is caused by a pathologic and destructive response of the organism as a result of the interaction between donor immunocompetent T lymphocytes and the recipient tisular antigens. It's considered the most serious complication of hematopoietic stem cell transplantation, most frequently described after bone marrow transplantation (BMT). The skin is usually the first and most commonly affected organ, in both acute and chronic, with a variable clinical spectrum of presentation. To report a case of vitiligo as a manifestation of cutaneous chronic GVHD, a low prevalence sign, which recognition could help to suspect this severe compli cation. 8 years old male, diagnosed with acute lymphoblastic leukemia (ALL) at 3 years old, had a combined medullary and central nervous system (NCS) relapse with minimal positive disease 3 years afterwards. After 4 years ALL was diagnosed, he received an allogeneic bone marrow transplant. Seven months after the BMT he prese...

Research paper thumbnail of Photoinhibition and photoprotection during flower opening in lilies

Plant science : an international journal of experimental plant biology, 2018

Although most studies to extend vase life in cut flowers have focused on flower senescence thus f... more Although most studies to extend vase life in cut flowers have focused on flower senescence thus far, flower opening is a complex process of major biological significance in the determination of flower commercialization. In order to better understand flower opening, this study evaluated to what extent photoinhibition and photo-oxidative stress are associated with tepal de-greening during flower opening in lilies (Lilium "Litouwen"). We estimated the degree of photoinhibition, the capacity for photo- and antioxidant protection, and the extent of lipid peroxidation at four flower opening stages, from closed flowers to anthesis. Additionally, we evaluated to what extent and by which mechanisms related to photo- and antioxidant protection, Promalin® (a combination of gibberellins and cytokinins) delays flower opening. Results showed that chlorophyll content decreased progressively during flower opening, while a sharp decrease of the maximum PSII efficiency (Fv/Fm ratio) was obs...

Research paper thumbnail of Erratum to: Gestural Representation of Emotions: A Comparative Study on Chilean and American Women

Journal of Child and Family Studies, 2017

Research paper thumbnail of Gestural Representation of Emotions: A Comparative Study on Chilean and American Women

Journal of Child and Family Studies, 2017

Emotions and their expression are adaptive processes, relevant to maintaining personal welfare an... more Emotions and their expression are adaptive processes, relevant to maintaining personal welfare and to structuring social relations through the verbal and nonverbal communication of feelings and needs to others. Emotional representation refers to the ability to intentionally and deliberately produce facial and bodily movements to convey an emotion. Although this representation possesses universal aspects, its richness lies in its cultural variability. This study seeks to describe and compare the intensity of the facial and bodily representation of six emotions in 120 Chilean and American women from different socioeconomic groups. The study adopts an investigatory, descriptive, cross-sectional and comparative design. A socio-demographic questionnaire and an assessment of emotional gestures in adults were applied. For the assessment, the women’s responses to six short stories related to the emotions of happiness, sadness, anger, fear, pride and shame were filmed and coded by independent coders from both countries. The results indicate that Chilean women are more intense when representing happiness and pride with their faces, whereas American women are more intense when representing happiness and anger with their bodies. In addition, differences emerge based on socioeconomic status. In both countries, a higher socioeconomic status is associated with greater intensity in the representation of emotions. The results and their implications are discussed.

Research paper thumbnail of Expediente - Apresentação - Sumário

Tcc Em Re Vista, Aug 30, 2013

Research paper thumbnail of Implication of Abscisic Acid on Ripening and Quality in Sweet Cherries: Differential Effects during Pre- and Post-harvest

Frontiers in Plant Science, 2016

Research paper thumbnail of Stimulus content effect on the visual cortex with functional MRI

Proceedings of the IEEE 24th Annual Northeast Bioengineering Conference (Cat. No.98CH36210)

Research paper thumbnail of Cortical activity in disparity vergence eye-movements: a fMRI study

Proceedings of the IEEE 24th Annual Northeast Bioengineering Conference (Cat. No.98CH36210), 1998

Employing fMRI techniques, cortical activity related with disparity vergence eye movements has be... more Employing fMRI techniques, cortical activity related with disparity vergence eye movements has been identified. The gyri precentralis, the gyrus cinguli and the precuneus appeared to be involved in these eye movements under very different conditions. In addition, the prediction operator in vergence eye movements presented additional activity in all the previous regions plus the gyrus frontalis superior. From this preliminary

Research paper thumbnail of A Recombinant Vesicular Stomatitis Virus Ebola Vaccine - Preliminary Report

The New England journal of medicine, 2015

Background The current Ebola virus disease (EVD) outbreak has resulted in more than 24,000 cases ... more Background The current Ebola virus disease (EVD) outbreak has resulted in more than 24,000 cases and 10,000 deaths. We present a preliminary report from two phase 1 trials of an attenuated, replication-competent, recombinant vesicular stomatitis virus (rVSV)-based vaccine candidate to prevent EVD. Methods We conducted two phase 1, placebo-controlled, double-blind, dose-escalation trials of an rVSV-based vaccine candidate expressing the glycoprotein of a Zaire strain of Ebola virus (ZEBOV). A total of 26 adults at each site (52 participants in all) were consecutively enrolled into groups of 13 each. Three volunteers in each group received an intramuscular injection of placebo, and 10 received an intramuscular injection of the rVSV-ZEBOV vaccine at a dose of either 3 million plaque-forming units (PFU) or 20 million PFU. Safety and immunogenicity were assessed for the 28 days after vaccination. Results The most common adverse events were injection-site pain, myalgia, and fatigue; no ev...

Research paper thumbnail of Abscisic Acid Synthesis and Signaling during the Ripening of Raspberry (Rubus idaeus ‘Heritage’) Fruit

Plants

The raspberry (Rubus idaeus L.) fruit is characterized by its richness in functional molecules an... more The raspberry (Rubus idaeus L.) fruit is characterized by its richness in functional molecules and high nutritional value, but the high rate of fruit softening limits its quality during postharvest. Raspberry drupelets have a particular ripening regulation, depending partially on the effect of ethylene produced from the receptacle. However, the possible role of abscisic acid (ABA) in the modulation of quality parameters during the ripening of raspberry is unclear. This study characterized the fruit quality-associated parameters and hormonal contents during fruit development in two seasons. The quality parameters showed typical changes during ripening: a drastic loss of firmness, increase in soluble solids content, loss of acidity, and turning to a red color from the large green stage to fully ripe fruit in both seasons. A significant increase in the ABA content was observed during the ripening of drupelets and receptacles, with the higher content in the receptacle of ripe and overri...

Research paper thumbnail of Modeling Objects with Uncertain Behaviors

The Journal of Object Technology

Research paper thumbnail of How alike are my physical and digital twins?

Proceedings of the 25th International Conference on Model Driven Engineering Languages and Systems: Companion Proceedings

A digital twin is a virtual replica of a system defined at a certain level of fidelity, and synch... more A digital twin is a virtual replica of a system defined at a certain level of fidelity, and synchronized at a specific frequency. Digital twins are often used to replicate physical systems whose simulations are usually computationally costly. One of the solutions proposed in the literature to this problem is to define a hierarchy of multi-fidelity digital twins, where we use one twin or another depending on the specific purpose. However, one of the challenges of this proposal is the need to determine whether these twins are equivalent to each other and the physical system according to their purpose. In this work, we explore different methods to measure this equivalence by analyzing the state and behavior of the twins using high-level software models. CCS CONCEPTS • Software and its engineering → Operational analysis.

Research paper thumbnail of Using trace alignments for measuring the similarity between a physical and its digital twin

Proceedings of the 25th International Conference on Model Driven Engineering Languages and Systems: Companion Proceedings

Research paper thumbnail of Measuring the fidelity of digital twin systems

Proceedings of the 25th International Conference on Model Driven Engineering Languages and Systems: Companion Proceedings

A digital twin is a virtual replica of a system at a certain level of fidelity, synchronized at a... more A digital twin is a virtual replica of a system at a certain level of fidelity, synchronized at a specific frequency. Digital twins often replicate physical systems whose simulations are usually computationally costly. One of the solutions to this problem proposed in the literature is to define a hierarchy of multi-fidelity digital twins, where we use one twin or another depending on the specific purpose. However, one of the challenges of this proposal is the need to determine whether the different twins are equivalent to each other and the physical system. In this thesis, we explore different methods to measure this equivalence by analyzing the state and behavior of the twins with the aid of high-level software models. CCS CONCEPTS • Software and its engineering → Operational analysis.

Research paper thumbnail of Revisiting Fault Localization Techniques for Model Transformations: Towards A Hybrid Approach

The Journal of Object Technology

Research paper thumbnail of PbSRT1 and PbSRT2 regulate pear growth and ripening yet displaying a species-specific regulation in comparison to other Rosaceae spp

Research paper thumbnail of Determinación del sexo en cráneo y mandíbula en una muestra contemporánea de Medellín

Maguaré, 2005

Se estudiaron 21 dimensiones en craneo y mandibula para analizar el dimorfi smo sexual en una mue... more Se estudiaron 21 dimensiones en craneo y mandibula para analizar el dimorfi smo sexual en una muestra de poblacion contemporanea de Medellin, utilizando con fi nes comparativos tres metodos diferentes de estima del dimorfi smo sexual. La magnitud de este, estimada mediante la t de Student proporciono un numero ligeramente mayor de dimensiones dimorficas que el test de Kolmogorov-Smirnov (KS) para muestras independientes. Sin embargo, la t de Student mostro resultados similares a los del test de la F (ANOVA) aplicado por Rosique et al. (2004) en un estudio precedente. El calculo del MDI (Mean Distance Index) fue superior al 5% en las dimensiones diagnosticadas simultaneamente como dimorfi cas por los tres test de signifi cacion (t, F y KS). El test de Kolmogorov-Smirnov se evidencio como recomendable para estimar el dimorfi smo sexual, frente a los otros tests, para varias dimensiones. Tanto el analisis univariado como el analisis discriminante evidenciaron un mayor poder diagnostico...

Research paper thumbnail of Transient photoinhibition and photo-oxidative stress as an integral part of stress acclimation and plant development in a dioecious tree adapted to Mediterranean ecosystems

Tree Physiology, 2021

Mastic trees (Pistacia lentiscus L.) are dioecious perennial plants that are highly adapted to Me... more Mastic trees (Pistacia lentiscus L.) are dioecious perennial plants that are highly adapted to Mediterranean climates but display a high sensitivity to winter periods. In order to understand how sex, leaf phenology and ecological context could condition sensitivity to winter and associated mechanisms to acclimate to these conditions, photoinhibition and photo-oxidative stress markers were examined in mastic trees (P. lentiscus) from a natural population growing in the Garraf Natural Park for a consecutive 12-month period (seasonal study), as well as in three populations naturally growing in the Montseny Natural Park, including the highest altitudes described for this species, during winter (altitudinal study). Results from these studies indicate that both the winter period and higher elevation influenced the degree of photoinhibition, but this was not conditioned by sex. In fact, winter photoinhibition occurred transiently even though it was accompanied by chlorophyll loss and malon...

Research paper thumbnail of Extending OCL with Subjective Logic

The Journal of Object Technology, 2020

Research paper thumbnail of Democracy against Parties? Party System Deinstitutionalization in Colombia

Journal of Politics in Latin America, 2011

This article argues that in Colombia, decentralization and electoral reforms adopted in the late ... more This article argues that in Colombia, decentralization and electoral reforms adopted in the late 1980s and in the 1991 Constitution – designed to improve democratic quality – brought about a gradual deinstitutionalization of this country's traditional party system as an unintended consequence. Building upon resource-based theories of party configuration, we contend that in developing countries, where resources are usually crucial for party aggregation, “democratizing” reforms designed to distribute power and resources in the political system can reduce local candidates’ incentives to join and remain loyal to political parties, particularly when those parties’ reputations are weak. In Colombia, these reforms (i) reduced the power of intermediate-level party leaders over the distribution of selective incentives, making these leaders less important for local politicians, and (ii) gave more political and financial autonomy to local candidates, reducing their need to join parties in ...

Research paper thumbnail of Vitiligo type cutaneous manifestation of chronic graft-versus-host disease. Case report

Revista chilena de pediatria, 2018

Graft-versus-host disease (GVHD) is caused by a pathologic and destructive response of the organi... more Graft-versus-host disease (GVHD) is caused by a pathologic and destructive response of the organism as a result of the interaction between donor immunocompetent T lymphocytes and the recipient tisular antigens. It's considered the most serious complication of hematopoietic stem cell transplantation, most frequently described after bone marrow transplantation (BMT). The skin is usually the first and most commonly affected organ, in both acute and chronic, with a variable clinical spectrum of presentation. To report a case of vitiligo as a manifestation of cutaneous chronic GVHD, a low prevalence sign, which recognition could help to suspect this severe compli cation. 8 years old male, diagnosed with acute lymphoblastic leukemia (ALL) at 3 years old, had a combined medullary and central nervous system (NCS) relapse with minimal positive disease 3 years afterwards. After 4 years ALL was diagnosed, he received an allogeneic bone marrow transplant. Seven months after the BMT he prese...

Research paper thumbnail of Photoinhibition and photoprotection during flower opening in lilies

Plant science : an international journal of experimental plant biology, 2018

Although most studies to extend vase life in cut flowers have focused on flower senescence thus f... more Although most studies to extend vase life in cut flowers have focused on flower senescence thus far, flower opening is a complex process of major biological significance in the determination of flower commercialization. In order to better understand flower opening, this study evaluated to what extent photoinhibition and photo-oxidative stress are associated with tepal de-greening during flower opening in lilies (Lilium "Litouwen"). We estimated the degree of photoinhibition, the capacity for photo- and antioxidant protection, and the extent of lipid peroxidation at four flower opening stages, from closed flowers to anthesis. Additionally, we evaluated to what extent and by which mechanisms related to photo- and antioxidant protection, Promalin® (a combination of gibberellins and cytokinins) delays flower opening. Results showed that chlorophyll content decreased progressively during flower opening, while a sharp decrease of the maximum PSII efficiency (Fv/Fm ratio) was obs...

Research paper thumbnail of Erratum to: Gestural Representation of Emotions: A Comparative Study on Chilean and American Women

Journal of Child and Family Studies, 2017

Research paper thumbnail of Gestural Representation of Emotions: A Comparative Study on Chilean and American Women

Journal of Child and Family Studies, 2017

Emotions and their expression are adaptive processes, relevant to maintaining personal welfare an... more Emotions and their expression are adaptive processes, relevant to maintaining personal welfare and to structuring social relations through the verbal and nonverbal communication of feelings and needs to others. Emotional representation refers to the ability to intentionally and deliberately produce facial and bodily movements to convey an emotion. Although this representation possesses universal aspects, its richness lies in its cultural variability. This study seeks to describe and compare the intensity of the facial and bodily representation of six emotions in 120 Chilean and American women from different socioeconomic groups. The study adopts an investigatory, descriptive, cross-sectional and comparative design. A socio-demographic questionnaire and an assessment of emotional gestures in adults were applied. For the assessment, the women’s responses to six short stories related to the emotions of happiness, sadness, anger, fear, pride and shame were filmed and coded by independent coders from both countries. The results indicate that Chilean women are more intense when representing happiness and pride with their faces, whereas American women are more intense when representing happiness and anger with their bodies. In addition, differences emerge based on socioeconomic status. In both countries, a higher socioeconomic status is associated with greater intensity in the representation of emotions. The results and their implications are discussed.

Research paper thumbnail of Expediente - Apresentação - Sumário

Tcc Em Re Vista, Aug 30, 2013

Research paper thumbnail of Implication of Abscisic Acid on Ripening and Quality in Sweet Cherries: Differential Effects during Pre- and Post-harvest

Frontiers in Plant Science, 2016

Research paper thumbnail of Stimulus content effect on the visual cortex with functional MRI

Proceedings of the IEEE 24th Annual Northeast Bioengineering Conference (Cat. No.98CH36210)

Research paper thumbnail of Cortical activity in disparity vergence eye-movements: a fMRI study

Proceedings of the IEEE 24th Annual Northeast Bioengineering Conference (Cat. No.98CH36210), 1998

Employing fMRI techniques, cortical activity related with disparity vergence eye movements has be... more Employing fMRI techniques, cortical activity related with disparity vergence eye movements has been identified. The gyri precentralis, the gyrus cinguli and the precuneus appeared to be involved in these eye movements under very different conditions. In addition, the prediction operator in vergence eye movements presented additional activity in all the previous regions plus the gyrus frontalis superior. From this preliminary

Research paper thumbnail of A Recombinant Vesicular Stomatitis Virus Ebola Vaccine - Preliminary Report

The New England journal of medicine, 2015

Background The current Ebola virus disease (EVD) outbreak has resulted in more than 24,000 cases ... more Background The current Ebola virus disease (EVD) outbreak has resulted in more than 24,000 cases and 10,000 deaths. We present a preliminary report from two phase 1 trials of an attenuated, replication-competent, recombinant vesicular stomatitis virus (rVSV)-based vaccine candidate to prevent EVD. Methods We conducted two phase 1, placebo-controlled, double-blind, dose-escalation trials of an rVSV-based vaccine candidate expressing the glycoprotein of a Zaire strain of Ebola virus (ZEBOV). A total of 26 adults at each site (52 participants in all) were consecutively enrolled into groups of 13 each. Three volunteers in each group received an intramuscular injection of placebo, and 10 received an intramuscular injection of the rVSV-ZEBOV vaccine at a dose of either 3 million plaque-forming units (PFU) or 20 million PFU. Safety and immunogenicity were assessed for the 28 days after vaccination. Results The most common adverse events were injection-site pain, myalgia, and fatigue; no ev...