Paula Viviana Arriero Leon - Academia.edu (original) (raw)
Uploads
Papers by Paula Viviana Arriero Leon
Acta Anaesthesiologica Scandinavica, 2006
Background: No study has determined the concentration of propofol producing a degree of hypnosis... more Background: No study has determined the concentration of propofol producing a degree of hypnosis compatible with anaesthesia in children. As a result, concentrations determined in adults are recommended for children. As this can result in an inadequate depth of anaesthesia, we determined the predicted effect site concentration (Ce) of propofol necessary to obtain a bispectral index (BIS) of 50 in 50% (ECe50) of children and adults.Methods: Twenty adults (aged 33–44 years) and 20 children (aged 3–11 years) undergoing surgery under general anaesthesia were studied. All were monitored with a BIS monitor, and a target controlled infusion of propofol aiming for a constant Ce value was started. After 10 min, patients were evaluated using a sedation scale, and the last 5 min was used to determine the mean BIS for this Ce value. The Ce value of propofol was defined using the up‐and‐down method of Dixon and Massey. The first patient in each group received Ce= 6 μg/ml; thereafter, it was mo...
Acta Anaesthesiologica Scandinavica, 2006
Background: No study has determined the concentration of propofol producing a degree of hypnosis... more Background: No study has determined the concentration of propofol producing a degree of hypnosis compatible with anaesthesia in children. As a result, concentrations determined in adults are recommended for children. As this can result in an inadequate depth of anaesthesia, we determined the predicted effect site concentration (Ce) of propofol necessary to obtain a bispectral index (BIS) of 50 in 50% (ECe50) of children and adults.Methods: Twenty adults (aged 33–44 years) and 20 children (aged 3–11 years) undergoing surgery under general anaesthesia were studied. All were monitored with a BIS monitor, and a target controlled infusion of propofol aiming for a constant Ce value was started. After 10 min, patients were evaluated using a sedation scale, and the last 5 min was used to determine the mean BIS for this Ce value. The Ce value of propofol was defined using the up‐and‐down method of Dixon and Massey. The first patient in each group received Ce= 6 μg/ml; thereafter, it was mo...