Peter Chlebo - Academia.edu (original) (raw)

Papers by Peter Chlebo

Journal of Food and Nutrition Research, 2017

$Research paper thumbnail of Phytonutrients of Bitter Apricot Seeds Modulate Human Lipid Profile and LDL Subfractions in Adults with Elevated Cholesterol Levels$

International Journal of Environmental Research and Public Health, 2022

The objective of the present study was to evaluate the effect of short-term consumption of bitter... more The objective of the present study was to evaluate the effect of short-term consumption of bitter apricot seeds phytonutrients on cardiovascular risk factors with a special focus on LDL cholesterol subfractions using the Lipoprint system. A group of 34 adult volunteers (21 female/13 male) consumed 60 mg kg−1 of body weight of bitter apricot seeds daily for 42 days. Subjects were divided into two groups: one with normal cholesterol levels (NTC) and one with elevated total cholesterol levels (ETC). Blood serum levels of total cholesterol (T-C), low-density cholesterol (LDL-C), high-density cholesterol (HDL-C), and triglycerides (TG) did not change significantly (p > 0.05) in NTC group. However, there were significant decreasing of T-C (p ˂ 0.05) and LDL-C (p < 0.01) in ETC group. The LDL1, LDL2, and atherogenic LDL3−7 subfractions progressively decreased after 42 days of apricot seeds consumption in ETC group (p < 0.05). Apricot seeds consumption was associated with a signifi...

European Respiratory Journal, 2011

Introduction: Chronic Obstructive Pulmonary Disease (COPD) is in close relation to chronic system... more Introduction: Chronic Obstructive Pulmonary Disease (COPD) is in close relation to chronic systemic inflammation involving an extrapulmonary patholgy. The results can be weight and muscle loss and nutritional abnormalities. FFMI (Fat Free Mass-index) assessment is important, because using Body Mass Index (BMI) does not distinguish between two people with a similar BMI but different body composition (BC). Aims: To determine FFMI and BMI in COPD patients (pts). Methods: In 2010, we began BC analysis on COPD patients with Dual-Energy X-ray Absorbtiometry (DEXA) in a prospective study trial. We analysed BC of 30 clinically stable COPD pts in stage II-IV GOLD. There were 24 M, median age 69 yrs (49-84 yrs) and 6 F, median age 74 yrs (51-85 yrs). For body composition analysis by DEXA we used Hologic Discovery Wi including the software “Whole Body Composition Analysis”. Reference intervals (by Schutz) for FFMI were used. Results: In M median BMI was 23 (17.7-33.99) and 23.34 (14.79-37.49) ...

Potravinarstvo Slovak Journal of Food Sciences, 2018

Genus Allium belongs to the family Alliaceae, which contains more than 600 species. Garlic (Alliu... more Genus Allium belongs to the family Alliaceae, which contains more than 600 species. Garlic (Allium sativum L.) is the most popular food ingredient widely used all over the world. During the last few decades, garlic has received tremendous attention for their wide range of therapeutic properties and great health benefits. Garlic has possessed antibacterial, antifungal, antiparasitic, antiviral, antioxidant, anticholesteremic, anti-cancerous, and vasodilator characteristics. In this work the total polyphenols content, total sulfur content and antioxidant activity was compared and evaluated in four studied varieties of garlic (Mojmír, Lukan, Záhorský and Makoi). The analyzed samples of garlic were collected at the stage of full maturity in the area Bardejov. The total polyphenols content was measured using the spectrophotometric method of Folin-Ciocalteu agents. The total polyphenols content in studied varieties of garlic were determined in the range 612.23 mg.kg-1 (Mojmír) to 566.01 m...

Czech Journal of Food Sciences, 2009

The goal of this study is the evaluation of enriched bread prepared with an addition of buckwheat... more The goal of this study is the evaluation of enriched bread prepared with an addition of buckwheat as a source of biologically active components in nutrition. Experimental pastry was baked using buckwheat wholegrain flour blended with wheat flour in different portions (10%, 20%, 30%, 40% and 50%) in order to observe the influence of buckwheat addition on dough processing and the quality of the final baked products. Taking into account the overall acceptability rating, it was concluded that bread with an addition of up to 30% of buckwheat could be baked with satisfactory evaluation results. The content of rutin in loaves in a consumable form prepared with a buckwheat addition varied between 7.76 mg/kg and 26.90 mg/kg. The clinical study which followed the baking experiment was based on the consumption of enriched bread (30% buckwheat, between 34.7 mg/kg and 38.2 mg/kg rutin content in dry matter) by a group of volunteers during a period of four weeks. The results approved the increase...

Chronobiology International, 2018

Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes, Jan 4, 2018

The present study was designed to reveal whether long-term consumption of bitter apricot seeds ca... more The present study was designed to reveal whether long-term consumption of bitter apricot seeds causes changes in lipid profile and other risk factors for cardiovascular diseases. The study group consisted of 12 healthy adult volunteers (5 females and 7 males). The average age of women was 41.60 ± 11.28 years and the average age of men was 36.71 ± 13.70 years. Volunteers consumed 60 mg kg of body weight of bitter apricot seeds divided into 8-12 doses daily for 12 weeks. Volunteers were recruited from the general population of Slovak Republic. After 12 weeks, mean body weight of the participants increased from 77.34 to 78.22 kg (P > 0.05). The average total cholesterol levels decreased from 4.86 mmol L at the beginning of the study to 4.44 mmol L at the end of the study (P < 0.05). We did not observe any significant increase in high-density cholesterol (from 1.55 to 1.60 mmol L). The average low-density cholesterol levels decreased from 2.93 mmol L at the beginning of the study ...

Roczniki Panstwowego Zakladu Higieny, 2016

Cigarette smoking is a major public health problem, which leads to the formation of chronic obstr... more Cigarette smoking is a major public health problem, which leads to the formation of chronic obstructive pulmonary disease (COPD) and is one of the main causes of avoidable death and disability worldwide. The aim of study was analysis and comparison of the visceral fat in the body of the three groups of subjects (non-smokers, smokers and COPD patients) by Tanita Viscan 140. The control group was composed of: (1) non-smokers (n=30), consisted of 13 males (43.4%) and 17 women (56.6%) - the average age was 52 ± 6.51 years and (2) smokers (n=30), consisted of 12 men (40%) and 18 women (60%) - the average age 46.53 ± 9.22 years. Study group consisted of patients with COPD (n=60), which consisted of 48 men (80%) and 12 women (20%). Mean age was 69.25 ± 9.90 years. The measurement of visceral fat by Tanita Viscan device 140, which uses bioelectrical impedance analysis to measure fat in the abdomen of the patient in the supine position. High levels of visceral fat (women from 36.9% to 52.3% ...

Nutrition research (New York, N.Y.), 2016

Cardiovascular diseases (CVDs) are the leading causes of death, and lifestyle modification, inclu... more Cardiovascular diseases (CVDs) are the leading causes of death, and lifestyle modification, including dietary changes, is recommended to improve this condition. In this study, regular consumption of bilberries was hypothesized to have beneficial effects on CVD risk reduction, by changes in human health indicators such as decreasing low-density lipoprotein cholesterol (LDL-C) and triglycerides (TGs) and increasing high-density lipoprotein cholesterol (HDL-C). The research involved women (n=25) and men (n=11) who consumed 150 g of frozen stored bilberries 3 times a week for 6 weeks. Anthropometric parameters, blood pressure, lipid profile, glucose, liver enzymes, creatinine, albumin, magnesium, and antiradical activity were measured. Except for the body mass index of women (P=.019), no significant changes were found for anthropometric indicators. The consumption of bilberries led to a decrease in the following parameters: total cholesterol (P=.017), LDL-C (P=.0347), TG (P=.001), gluco...

Journal of the Science of Food and Agriculture, 2014

γ-Aminobutyric acid (GABA) is a potentially bioactive component of foods and pharmaceuticals. The... more γ-Aminobutyric acid (GABA) is a potentially bioactive component of foods and pharmaceuticals. The aim of this study was screen lactic acid bacteria belonging to the Czech Collection of Microorganisms, and microorganisms (yeast and bacteria) from 10 different food sources for GABA production by fermentation in broth or plant and animal products. Under an aerobic atmosphere, very low selectivity of GABA production (from 0.8% to 1.3%) was obtained using yeast and filamentous fungi, while higher selectivity (from 6.5% to 21.0%) was obtained with bacteria. The use of anaerobic conditions, combined with the addition of coenzyme (pyridoxal-5-phosphate) and salts (CaCl2 , NaCl), led to the detection of a low concentration of GABA precursor. Simultaneously, using an optimal temperature of 33 °C, a pH of 6.5 and bacteria from banana (Pseudomonadaceae and Enterobacteriaceae families), surprisingly, a high selectivity of GABA was obtained. A positive impact of fenugreek sprouts on the proteolytic process and GABA production from plant material as a source of GABA precursor was identified. Lactic acid bacteria for the production of new plant and animal GABA-rich products from different natural sources containing GABA precursor can be used. © 2014 Society of Chemical Industry.

Autors in the paper submit rewiev about favourable reactions drinking low doses of wine on the he... more Autors in the paper submit rewiev about favourable reactions drinking low doses of wine on the health. On the basis of these facts, it is possible to state, that the drinking low doses of wine every day (max. 2-3 dcl) has beneficial effect on the organism, which was confirmed by a lot of very long and large studies. The antioxidants are the base of this preventive effect, which are present in the increase concentration a stabil state in the wine and their positive influence on the cholesterol levels (increase of HDL cholesterol level and decrease of LDL cholesterol level), antitrombotic effect by decreasing of plasmatic fibrinogen level, increasing fibrinolytic activity and decrease of activity of blood platelets and antioxidant effect of fenolic matters-flavonoids (especially resveratol, quarcetin and katechin), which is by their redox qualities and potentials, which protected to origin and development of oxidative stress.

Epidemiological, experimental and clinical investigations have shown that diets supplemented with... more Epidemiological, experimental and clinical investigations have shown that diets supplemented with moderate quantities of alcoholic beverages lead to biochemical changes, that are widely regarded to prevent cardiovascular disease. Red wine contains a naturally rich sources of antioxidants which may protect the body from oxidative stress. We investigated the relationship between red wine intake and lipide profile, glucose, blood pressure and WHR index changes. Participants consumed 200 ml of red wine Lemberger (MASARYK, Slovakia) each day during supper for six weeks and were encouraged to maintain their usual diet and exercise habits. Daily intake of Lemberger during six weeks was associated with lower plasma levels of total cholesterol (5.66±1. contrary we recorded higher level of "good" HDL cholesterol (1.42±0.63 vs 1.80±0.58). Systolic and diastolic blood pressure was also decreased. Research results have shown that moderate consumption of red wine have a positive impact ...