Peter Credico - Academia.edu (original) (raw)

Papers by Peter Credico

Research paper thumbnail of A Convolutional Neural Network based system for classifying malignant and benign skin lesions using mobile-device images

medRxiv (Cold Spring Harbor Laboratory), Dec 5, 2023

The escalating incidence of skin lesions, coupled with a scarcity of dermatologists and the intri... more The escalating incidence of skin lesions, coupled with a scarcity of dermatologists and the intricate nature of diagnostic procedures, has resulted in prolonged waiting periods. Consequently, morbidity and mortality rates stemming from untreated cancerous skin lesions have witnessed an upward trend. To address this issue, we propose a skin lesion classification model that leverages the efficient net B7 Convolutional Neural Network (CNN) architecture, enabling early screening of skin lesions based on camera images. The model is trained on a diverse dataset encompassing eight distinct skin lesion classes: Basal Cell Carcinoma (BCC), Squamous Cell Carcinoma (SCC), Melanoma (MEL), Dysplastic Nevi (DN), Benign Keratosis-Like lesions (BKL), Melanocytic Nevi (NV), and an 'Other' class. Through multiple iterations of data preprocessing, as well as comprehensive error analysis, the model achieves a remarkable accuracy rate of 87%.

Research paper thumbnail of Determinants of Success in Single- and Multi-Digit Replant

Plastic surgery, Jun 23, 2021

Purpose: Understanding the variables that influence success in digital replant surgery is essenti... more Purpose: Understanding the variables that influence success in digital replant surgery is essential to guide clinical decision-making and to counsel patients. The purpose of this study was to determine the replant success rate and identify predictors of success at our tertiary care centre. Methods: This was a single centre, retrospective cohort study of consecutive patients who underwent digital replantation from January 2000 to September 2018. Adult patients with flexor zone I to III amputations were included. Patient demographics, comorbidities, injury pattern, operative data, and post-operative care were reviewed. The primary outcome was survival of the replanted digit at discharge. Results: A total of 146 patients met inclusion criteria. Of these, 100 had single-digit replants and 46 underwent multi-digit replants for a total of 220 digits. The success rate was 71%. Predictors of success included sharp mechanism of injury (P < .01), incomplete amputation (P < .01), amputation proximal to zone I flexor level (P = .02), post-operative acetylsalicylic acid use (P < .01), absence of leech use (P = .05), and absence of operative re-exploration (P < .01). Daytime replants had similar outcome compared to nighttime replants despite having increased ischemia time (7.9 ± 3.9 hours vs 6.8 ± 2.6 hours, P = .02). However, daytime operative time (7.8 ± 3.7 hours) was significantly shorter than nighttime replant time (9.6 ± 5.9 hours, P = .01). Conclusion: Sharp amputation, intact venous drainage, proximal amputation, and acetylsalicylic acid use were associated with replant survival and are factors to consider when managing patients for digital replantation. Leech therapy and operative re-exploration were associated with poor outcome. Nighttime replants required significantly longer operative time than daytime replants despite similar survival outcome.

Research paper thumbnail of Determinants of Success in Single- and Multi-Digit Replant

Plastic Surgery, 2021

Purpose: Understanding the variables that influence success in digital replant surgery is essenti... more Purpose: Understanding the variables that influence success in digital replant surgery is essential to guide clinical decision-making and to counsel patients. The purpose of this study was to determine the replant success rate and identify predictors of success at our tertiary care centre. Methods: This was a single centre, retrospective cohort study of consecutive patients who underwent digital replantation from January 2000 to September 2018. Adult patients with flexor zone I to III amputations were included. Patient demographics, comorbidities, injury pattern, operative data, and post-operative care were reviewed. The primary outcome was survival of the replanted digit at discharge. Results: A total of 146 patients met inclusion criteria. Of these, 100 had single-digit replants and 46 underwent multi-digit replants for a total of 220 digits. The success rate was 71%. Predictors of success included sharp mechanism of injury (P < .01), incomplete amputation (P < .01), amputat...

Research paper thumbnail of A Convolutional Neural Network based system for classifying malignant and benign skin lesions using mobile-device images

medRxiv (Cold Spring Harbor Laboratory), Dec 5, 2023

The escalating incidence of skin lesions, coupled with a scarcity of dermatologists and the intri... more The escalating incidence of skin lesions, coupled with a scarcity of dermatologists and the intricate nature of diagnostic procedures, has resulted in prolonged waiting periods. Consequently, morbidity and mortality rates stemming from untreated cancerous skin lesions have witnessed an upward trend. To address this issue, we propose a skin lesion classification model that leverages the efficient net B7 Convolutional Neural Network (CNN) architecture, enabling early screening of skin lesions based on camera images. The model is trained on a diverse dataset encompassing eight distinct skin lesion classes: Basal Cell Carcinoma (BCC), Squamous Cell Carcinoma (SCC), Melanoma (MEL), Dysplastic Nevi (DN), Benign Keratosis-Like lesions (BKL), Melanocytic Nevi (NV), and an 'Other' class. Through multiple iterations of data preprocessing, as well as comprehensive error analysis, the model achieves a remarkable accuracy rate of 87%.

Research paper thumbnail of Determinants of Success in Single- and Multi-Digit Replant

Plastic surgery, Jun 23, 2021

Purpose: Understanding the variables that influence success in digital replant surgery is essenti... more Purpose: Understanding the variables that influence success in digital replant surgery is essential to guide clinical decision-making and to counsel patients. The purpose of this study was to determine the replant success rate and identify predictors of success at our tertiary care centre. Methods: This was a single centre, retrospective cohort study of consecutive patients who underwent digital replantation from January 2000 to September 2018. Adult patients with flexor zone I to III amputations were included. Patient demographics, comorbidities, injury pattern, operative data, and post-operative care were reviewed. The primary outcome was survival of the replanted digit at discharge. Results: A total of 146 patients met inclusion criteria. Of these, 100 had single-digit replants and 46 underwent multi-digit replants for a total of 220 digits. The success rate was 71%. Predictors of success included sharp mechanism of injury (P &lt; .01), incomplete amputation (P &lt; .01), amputation proximal to zone I flexor level (P = .02), post-operative acetylsalicylic acid use (P &lt; .01), absence of leech use (P = .05), and absence of operative re-exploration (P &lt; .01). Daytime replants had similar outcome compared to nighttime replants despite having increased ischemia time (7.9 ± 3.9 hours vs 6.8 ± 2.6 hours, P = .02). However, daytime operative time (7.8 ± 3.7 hours) was significantly shorter than nighttime replant time (9.6 ± 5.9 hours, P = .01). Conclusion: Sharp amputation, intact venous drainage, proximal amputation, and acetylsalicylic acid use were associated with replant survival and are factors to consider when managing patients for digital replantation. Leech therapy and operative re-exploration were associated with poor outcome. Nighttime replants required significantly longer operative time than daytime replants despite similar survival outcome.

Research paper thumbnail of Determinants of Success in Single- and Multi-Digit Replant

Plastic Surgery, 2021

Purpose: Understanding the variables that influence success in digital replant surgery is essenti... more Purpose: Understanding the variables that influence success in digital replant surgery is essential to guide clinical decision-making and to counsel patients. The purpose of this study was to determine the replant success rate and identify predictors of success at our tertiary care centre. Methods: This was a single centre, retrospective cohort study of consecutive patients who underwent digital replantation from January 2000 to September 2018. Adult patients with flexor zone I to III amputations were included. Patient demographics, comorbidities, injury pattern, operative data, and post-operative care were reviewed. The primary outcome was survival of the replanted digit at discharge. Results: A total of 146 patients met inclusion criteria. Of these, 100 had single-digit replants and 46 underwent multi-digit replants for a total of 220 digits. The success rate was 71%. Predictors of success included sharp mechanism of injury (P < .01), incomplete amputation (P < .01), amputat...