Peter Torre - Academia.edu (original) (raw)

Papers by Peter Torre

Perspectives on Hearing and Hearing Disorders Research and Diagnostics, 2015

Ear and Hearing, Mar 1, 2003

The primary purpose of this study was to determine the distortion product otoacoustic emission (D... more The primary purpose of this study was to determine the distortion product otoacoustic emission (DPOAE) and noise response characteristics in a large sample of older adults. Another purpose was to evaluate how specific absolute DPOAE levels or DPOAE/Noise ratios differentiated hearing status in these individuals.

Neurotoxicology and Teratology, Nov 1, 2001

Thirty-one female rhesus monkeys were randomly assigned to three lead exposure conditions (none, ... more Thirty-one female rhesus monkeys were randomly assigned to three lead exposure conditions (none, birth to 1 year, and birth to 2 years). Blood lead levels were maintained at 35 -40 mg/dl beginning shortly after birth and continuing for 1 or 2 years postnatally. Auditory function was assessed in these monkeys at least 1 year after exposure to lead. The outcome measures included tympanometry to assess middle ear function, otoacoustic emissions (OAEs) to assess cochlear function, and auditory brainstem-evoked responses (ABRs) to assess the auditory nerve and brainstem pathways. There were no significant differences among the three experimental groups for any of the tympanometric variables measured suggesting no effect of lead exposure on middle ear function. Suprathreshold and threshold distortion product OAEs (DPOAEs) were comparable among the three groups. Finally, the auditory-evoked response at levels from the auditory nerve to the cerebral cortex did not significantly differ as a function of lead exposure. The lead exposure in this study had little effect on auditory function. D

JAMA otolaryngology-- head & neck surgery, Jan 28, 2015

Hearing impairment is common in adults, but few studies have addressed it in the US Hispanic/Lati... more Hearing impairment is common in adults, but few studies have addressed it in the US Hispanic/Latino population. To determine the prevalence of hearing impairment among US Hispanic/Latino adults of diverse backgrounds and determine associations with potential risk factors. The Hispanic Community Health Study/Study of Latinos (HCHS/SOL) is a population-based sample of Hispanics/Latinos in four US communities (Bronx, New York; Chicago, Illinois; Miami, Florida; and San Diego, California). Examinations were conducted from 2008 through 2011. The HCHS/SOL examined 16 415 self-identified Hispanic/Latino persons aged 18 to 74 years recruited from randomly selected households using a stratified 2-stage area probability sample design based on census block groups and households within block groups. Hearing thresholds were measured by pure-tone audiometry. Hearing impairment was defined as a pure-tone average (PTA) of thresholds at 0.5, 1, 2, and 4 kHz greater than 25 dB hearing level. Bilatera...

AIDS care, Jan 11, 2015

Researchers are showing that the rate of hearing loss in children with perinatal HIV infection (P... more Researchers are showing that the rate of hearing loss in children with perinatal HIV infection (PHIV) is higher than in HIV-unexposed, uninfected children. These data, however, have been collected mostly in the USA; extensive hearing data from low- and middle-income countries are lacking. The purpose of this study was to collect audiometric data in PHIV and HIV-uninfected children living in Cape Town, South Africa. Questionnaire data along with distortion product otoacoustic emissions (DPOAEs) and pure-tone testing were completed. Hearing loss was determined using the pure-tone thresholds defined as a pure-tone average (PTA) of 500, 1000, 2000, and 4000 Hz of >15 dB HL in the poorer ear. All data were compared between PHIV and HIV-uninfected children. Sixty-one (37 PHIV and 24 HIV-uninfected) children had hearing data. HIV status was not significantly associated with DPOAEs. The rate of conductive hearing loss was 11.5%; five PHIV and two HIV-uninfected children. The rate of any ...

Journal of the American Academy of Audiology, 2014

Young adults experience some type of recreational noise exposure on a daily basis; this includes ... more Young adults experience some type of recreational noise exposure on a daily basis; this includes using personal music (PM) systems with earphones. In most cases, this exposure is intermittent and the short-term effects of this exposure on the auditory system are becoming better understood. The purpose of this study was to examine the effects of one hour of music exposure using a PM system on distortion product otoacoustic emission (DPOAE) absolute levels and generator and characteristic frequency (CF) component levels. Young adults (n = 101) between 18-30 years with normal hearing participated listened to one hour of music through earphones. A second group of young adults (n = 21) served as controls and did not listen to music, but sat in the sound-treated room for one hour. Otoscopy, tympanometry, and a hearing screening (≤20 dB HL at 0.5, 1, 2, and 4 kHz) were completed in a randomly determined test ear. Preferred listening level, in dBA, was obtained and DPOAEs (2f1-f2) were meas...

The Pediatric Infectious Disease Journal, 2014

The effect of perinatal HIV infection and exposure on sub-clinical auditory function can be measu... more The effect of perinatal HIV infection and exposure on sub-clinical auditory function can be measured with distortion product otoacoustic emissions (DPOAEs). DPOAEs were obtained at 4 frequency bins (1, 2, 3 and 4 kHz) and categorized by a signal-to-noise ratio. HIV infection was not associated with poorer DPOAEs. Among HIV-infected children, HIV viral load ≥400 copies/mL had significantly lower odds of better DPOAEs.

BMC Infectious Diseases, 2014

Neurobiology of Aging, 2004

Age-related alterations in auditory function were evaluated in adult male rhesus monkeys (Macaca ... more Age-related alterations in auditory function were evaluated in adult male rhesus monkeys (Macaca mulatta) involved in a long-term study evaluating the effects of caloric restriction (CR) on aging. We assessed 26 monkeys in a control group fed a low fat, high fiber diet at approximately ad libitum levels and 24 monkeys in a CR group that were fed the same diet reduced in amount by 30% compared to age- and weight-matched controls. The following measures of auditory function were obtained while monkeys were maintained under anesthesia: (1) distortion product otoacoustic emissions (DPOAEs); (2) auditory brainstem responses (ABRs); and (3) middle latency responses (MLRs). All DPOAE measures and peak II amplitude significantly decreased with age, while peak IV latency and ABR threshold significantly increased with age. We found no significant effects of CR on any auditory parameters examined.

Hearing research, Jan 22, 2015

Despite a robust hearing conservation program, military personnel continue to be at high risk for... more Despite a robust hearing conservation program, military personnel continue to be at high risk for noise induced hearing loss (NIHL). For more than a decade, a number of laboratories have investigated the use of antioxidants as a safe and effective adjunct to hearing conservation programs. Of the antioxidants that have been investigated, N-acetylcysteine (NAC) has consistently reduced permanent NIHL in the laboratory, but its clinical efficacy is still controversial. This study provides a prospective, randomized, double-blinded, placebo-controlled clinical trial investigating the safety profile and the efficacy of NAC to prevent hearing loss in a military population after weapons training. Of the 566 total study subjects, 277 received NAC while 289 were given placebo. The null hypothesis for the rate of STS was not rejected based on the measured results. While no significant differences were found for the primary outcome, rate of threshold shifts, the right ear threshold shift rate d...

The Pediatric Infectious Disease Journal, 2012

The user has requested enhancement of the downloaded file. All in-text references underlined in b... more The user has requested enhancement of the downloaded file. All in-text references underlined in blue are linked to publications on ResearchGate, letting you access and read them immediately. The Pediatric Infectious Disease Journal www.pidj.com | 835

Otology & Neurotology, 2010

1. To correlate exostosis severity with ear canal evaporative cooling. 2. To assess hearing and c... more 1. To correlate exostosis severity with ear canal evaporative cooling. 2. To assess hearing and complications after canalplasty. Retrospective chart review. A retrospective chart review from 1990 to 2007 at a university tertiary referral center. Surfers from the west coast of the United States were twice as likely to have severe exostoses in the right ear compared with the left. Evaporative cooling from a predominant northerly wind direction during the coldest water temperature months in this region may contribute to this lateral bias because surfers on this coast spend most of their time facing west. Few postoperative complications were identified. No cases of facial nerve injury or entry into the temporomandibular joint occurred. Differences in preoperative versus postoperative pure-tone hearing thresholds were not significant. Exostosis severity seems to correspond to the ear that is more exposed to the predominant coastal wind. We propose that evaporative cooling in a cold water environment contributes to greater progression of exostoses in the ear with more exposure to the predominant wind. Exostosis removal using the postauricular approach carries a low complication rate.

Otolaryngology - Head and Neck Surgery, 2009

To investigate the effect of high-frequency over stimulation on duration tuning in low-frequency ... more To investigate the effect of high-frequency over stimulation on duration tuning in low-frequency inferior colliculus neurons in guinea pigs. METHODS: Duration tuning pattern was recorded by measuring the spikes of single neurons in response to the best frequency (BF) of different durations. The effect of high frequency over stimulation was verified by comparing the responses before and after the tone exposure. RESULTS: In total, 40 duration-tuned neurons were successfully recorded before and after the tone exposure. After the high frequency tone trauma, a total of 29 neurons (72.5%) became non-duration tuned. CONCLUSIONS: High-frequency over stimulation can cause the loss of duration selectivity in low-frequency inferior colliculus neurons in guinea pigs.

Neurotoxicology and Teratology, 2001

Journal of the American Academy of Audiology, 2007

The purpose of this study was to evaluate the possible effects of risk factors on distortion prod... more The purpose of this study was to evaluate the possible effects of risk factors on distortion product otoacoustic emissions (DPOAEs) in young adult men with normal hearing. Four hundred thirty-six United States Marine recruit men (mean age = 19.2 years +/- 1.8 years; age range = 17-29 years) participated in this study. Questionnaires were given to each recruit to obtain demographic data and history of noise exposure, solvent exposure, smoking history, and hearing-related histories. Otoscopy, tympanometry, pure-tone air-conduction audiometry (2.0-8.0 kHz) and DPOAEs (2.3-8.0 kHz) were measured. DPOAE levels were lower in Not Hispanic or Latino recruits, in heavy smokers, in recruits who reported loud live music exposure and ringing in their ears after noise exposure. These differences were not statistically significant at all frequencies. Recruits with multiple risk factors had the lowest DPOAEs as compared to recruits with fewer, or no, risk factors; these differences were not statistically significant. Obtaining risk factor data as part of an audiometric evaluation is important even though the individual may have normal hearing.

Journal of Speech, Language, and Hearing Research, 2005

The purpose of this research was to evaluate the relation between self-reported cardiovascular di... more The purpose of this research was to evaluate the relation between self-reported cardiovascular disease (CVD) and cochlear function in older adults. The Epidemiology of Hearing Loss Study (EHLS) is an ongoing population-based study of hearing loss and its risk factors in Beaver Dam, Wisconsin. As part of the EHLS questionnaire, participants were asked about their cardiovascular medical history. CVD history was determined from questions regarding history of angina, myocardial infarction (MI), and stroke. Questions about the use of antihypertensive medication and blood pressure measurements determined the presence or absence of hypertension. Among the audiologic measures completed were distortion product otoacoustic emissions (DPOAEs). Cochlear function was measured using DPOAEs and participants were categorized as having (a) cochlear impairment, (b) possible cochlear impairment, or (c) no cochlear impairment. There were 1,501 participants with complete CVD and DPOAE data from the 1998-2000 examination phase. Women with a self-reported history of MI were twice as likely (age-adjusted odds ratio [OR] = 2.00, 95% confidence interval [CI] = 1.15-3.46) to have cochlear impairment than women without a history of MI. This association was not significant in men (age-adjusted OR = 0.98, 95% CI = 0.61-1.58). Additionally, no other CVD variables were associated with cochlear impairment. This study provides data on a possible sex-specific association between CVD and DPOAEs in older adults.

Journal of Developmental & Behavioral Pediatrics, 2011

Objective-To investigate risk for language impairment in children perinatally infected or exposed... more Objective-To investigate risk for language impairment in children perinatally infected or exposed to HIV.

Journal of Communication Disorders, 2008

The purpose of this study was to measure noise levels during aerobics classes and to examine how ... more The purpose of this study was to measure noise levels during aerobics classes and to examine how outer hair cell (OHC) function, using distortion product otoacoustic emissions (DPOAEs), may be affected by this exposure. Fifty individuals (48 women and 2 men, ages 19-41 years) participated in 50-min aerobics classes. Noise levels were measured using noise dosimeters placed on the collar near the test ear. The audiometric protocol consisted of a questionnaire, otoscopy, screening tympanometry, and pre- and post-aerobics DPOAEs. The minute-by-minute peak noise levels varied between 90.5 and 99.7dBA. The overall mean noise level for the aerobics classes was 87.1dBA (range=83.4-90.7dBA). Mean post-aerobic DPOAE levels were lower at most frequencies with a statistically significant 1.4dB decrease at 6000Hz. Results of this project, even with limited statistical significance, should be viewed cautiously. The reader will be able to (1) identify the approximate dB SPL measured during aerobics classes, (2) describe what effects, if any, these levels had on DPOAEs, and (3) discuss what specific frequency had a significant decrease in DPOAE level after an aerobics class.

International Journal of Audiology, 2006

The purpose of this study was to examine the accuracy of self-reported hearing loss in older Lati... more The purpose of this study was to examine the accuracy of self-reported hearing loss in older Latino-American adults. Fifty-nine individuals, 32 women (mean age 62.2 years) and 27 men (mean age 62.4 years), participated. The questionnaire addressed hearing loss, hearing aid use, and other people&amp;amp;amp;amp;amp;amp;amp;#39;s views of their hearing abilities. Based on the question, &amp;amp;amp;amp;amp;amp;amp;#39;Do you feel you have a hearing loss?&amp;amp;amp;amp;amp;amp;amp;#39;, the prevalence of self-reported hearing loss was 57.6%, with 56.3% of women and 59.3% of men reporting a hearing loss. Sensitivity, specificity, and accuracy were calculated using this question and compared to the pure-tone average (PTA) at 500, 1000, 2000, and 4000 Hz in the poorer ear. Overall, sensitivity was 75.7%, specificity was 72.7%, and accuracy was 74.6%. Results of this smaller scale study suggest that a single question, used as a screening measure, is both sensitive and specific for hearing loss in older Latino-American adults and may overcome language and cultural barriers. This question can be easily implemented by physicians or other health-care employees to quickly screen for hearing loss.