Pham Nguyen Cuong - Academia.edu (original) (raw)

Papers by Pham Nguyen Cuong

Research paper thumbnail of Vai trò của xét nghiệm tìm đột biến gen EGFR trong chẩn đoán ung thư phổi không tế bào nhỏ tại Bệnh viện Trung ương Huế

Journal of Clinical Medicine- Hue Central Hospital

Research paper thumbnail of Histopathological Features of Deep Soft Tissue Epithelioid Angiosarcoma in the Lower Extremity: A Rare Case Report

American Journal of Case Reports, 2020

Objective: Rare disease Background: Epithelioid angiosarcoma is an extremely rare malignant disea... more Objective: Rare disease Background: Epithelioid angiosarcoma is an extremely rare malignant disease of the endothelial cells. Most of the previous reports about this disease were regarding clinical features and radiological findings, with limited descriptions of pathological diagnosis. This report aimed to present a reference to increase understanding of the timely diagnosis of epithelioid angiosarcoma. Case Report: A 65-year-old male was diagnosed with epithelioid angiosarcoma originating from the deep soft tissue of the lower leg. He had a history of 2 months of rapid swelling and painful in the left lower leg, which occurred after a muscle cramp, and was clinically suspicioius for hematoma. Radiological examination revealed a large heterogeneous soft-tissue mass. Histopathology results showed that the mass was malignant, and the differential diagnosis wasa malignant vascular tumor, melanoma, poorly differentiated carcinoma, clear cell sarcoma, epithelioid sarcoma, and anaplastic large-cell lymphoma. Immunohistochemistry findings confirmed that it was an epithelioid angiosarcoma. Conclusions: This case underscores the difficult of diagnosing epithelioid angiosarcoma. It requires careful pathological investigation and immunophenotype labeling.

Research paper thumbnail of Giant congenital pancreatic cyst in a neonate

Journal of pediatric surgery case reports, 2021

Pancreatic cysts in infants are rare. To the best of our knowledge, there are only 38 cases of pa... more Pancreatic cysts in infants are rare. To the best of our knowledge, there are only 38 cases of pancreatic cysts detected among children under 2 years of age. To date, no pediatric case has been reported in Vietnam. Due to its limited incidence, the correct diagnosis and optimal management are still not clearly defined. Here, we present the successful excision of a true congenital pancreatic cyst in a newborn at our center. Literature on this topic was also reviewed.

Research paper thumbnail of Pathological Characteristics of Nasopharyngeal Carcinoma in Hue Central Hospital

Journal of US-China Medical Science, 2019

Materials and Methods: This was a retrospective review of all patients seen at Pathology Departme... more Materials and Methods: This was a retrospective review of all patients seen at Pathology Department, Hue Central Hospital with the diagnosis of nasopharyngeal carcinoma between January 1, 2017 and June 30, 2018. The patient's clinical data and histopathological findings are presented. The histopathological diagnosis was in accordance with the World Health Organization (WHO) 1991 classification table. Results: A total of 73 patients with histologically confirmed nasopharyngeal carcinoma were recorded at Hue Central Hospital. There were 53 males and 20 females. Histologically, undifferentiated carcinoma was the commonest (71.2%) followed by well-differentiated keratinizing squamous cell carcinoma (20.6%) and other carcinoma (8.2%). Immunohistochemistry with CKAE1/3 was positive to 32/32 of well-differentiated keratinizing squamous cell carcinoma, and negative to 30/32 of undifferentiated carcinoma.

Research paper thumbnail of Histopathological Characteristics of Gastrointestinal Stromal Tumors in a Cohort of Vietnamese Patients

Clinical Pathology, 2020

Introduction:Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal neoplasms of... more Introduction:Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal neoplasms of the gastrointestinal system. Histopathological examination takes an important part in confirming the subtypes of GISTs, to choose appropriate therapeutics for patients. This study aims to explore the histopathological characteristics and evaluate the relationship between malignant risk classification (according to Armed Forces Institute of Pathology criteria) and the histopathological features of GISTs in a cohort of Vietnamese patients.Methods:We reviewed 89 patients with primary GIST who underwent surgery between 2014 and 2019 at Hue Central Hospital, Vietnam. We investigated histopathological characteristics and immunohistochemical findings of all patients.Results:The average age was 55.9 ± 11.9 years. A tumor size of 2-5 cm accounted for 64.1%. The most common position was at the stomach which accounted for 48.5%. Among the subtypes of GIST, spindle cells were seen in 85.9% of patie...

Research paper thumbnail of Vai trò của xét nghiệm tìm đột biến gen EGFR trong chẩn đoán ung thư phổi không tế bào nhỏ tại Bệnh viện Trung ương Huế

Journal of Clinical Medicine- Hue Central Hospital

Research paper thumbnail of Histopathological Features of Deep Soft Tissue Epithelioid Angiosarcoma in the Lower Extremity: A Rare Case Report

American Journal of Case Reports, 2020

Objective: Rare disease Background: Epithelioid angiosarcoma is an extremely rare malignant disea... more Objective: Rare disease Background: Epithelioid angiosarcoma is an extremely rare malignant disease of the endothelial cells. Most of the previous reports about this disease were regarding clinical features and radiological findings, with limited descriptions of pathological diagnosis. This report aimed to present a reference to increase understanding of the timely diagnosis of epithelioid angiosarcoma. Case Report: A 65-year-old male was diagnosed with epithelioid angiosarcoma originating from the deep soft tissue of the lower leg. He had a history of 2 months of rapid swelling and painful in the left lower leg, which occurred after a muscle cramp, and was clinically suspicioius for hematoma. Radiological examination revealed a large heterogeneous soft-tissue mass. Histopathology results showed that the mass was malignant, and the differential diagnosis wasa malignant vascular tumor, melanoma, poorly differentiated carcinoma, clear cell sarcoma, epithelioid sarcoma, and anaplastic large-cell lymphoma. Immunohistochemistry findings confirmed that it was an epithelioid angiosarcoma. Conclusions: This case underscores the difficult of diagnosing epithelioid angiosarcoma. It requires careful pathological investigation and immunophenotype labeling.

Research paper thumbnail of Giant congenital pancreatic cyst in a neonate

Journal of pediatric surgery case reports, 2021

Pancreatic cysts in infants are rare. To the best of our knowledge, there are only 38 cases of pa... more Pancreatic cysts in infants are rare. To the best of our knowledge, there are only 38 cases of pancreatic cysts detected among children under 2 years of age. To date, no pediatric case has been reported in Vietnam. Due to its limited incidence, the correct diagnosis and optimal management are still not clearly defined. Here, we present the successful excision of a true congenital pancreatic cyst in a newborn at our center. Literature on this topic was also reviewed.

Research paper thumbnail of Pathological Characteristics of Nasopharyngeal Carcinoma in Hue Central Hospital

Journal of US-China Medical Science, 2019

Materials and Methods: This was a retrospective review of all patients seen at Pathology Departme... more Materials and Methods: This was a retrospective review of all patients seen at Pathology Department, Hue Central Hospital with the diagnosis of nasopharyngeal carcinoma between January 1, 2017 and June 30, 2018. The patient's clinical data and histopathological findings are presented. The histopathological diagnosis was in accordance with the World Health Organization (WHO) 1991 classification table. Results: A total of 73 patients with histologically confirmed nasopharyngeal carcinoma were recorded at Hue Central Hospital. There were 53 males and 20 females. Histologically, undifferentiated carcinoma was the commonest (71.2%) followed by well-differentiated keratinizing squamous cell carcinoma (20.6%) and other carcinoma (8.2%). Immunohistochemistry with CKAE1/3 was positive to 32/32 of well-differentiated keratinizing squamous cell carcinoma, and negative to 30/32 of undifferentiated carcinoma.

Research paper thumbnail of Histopathological Characteristics of Gastrointestinal Stromal Tumors in a Cohort of Vietnamese Patients

Clinical Pathology, 2020

Introduction:Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal neoplasms of... more Introduction:Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal neoplasms of the gastrointestinal system. Histopathological examination takes an important part in confirming the subtypes of GISTs, to choose appropriate therapeutics for patients. This study aims to explore the histopathological characteristics and evaluate the relationship between malignant risk classification (according to Armed Forces Institute of Pathology criteria) and the histopathological features of GISTs in a cohort of Vietnamese patients.Methods:We reviewed 89 patients with primary GIST who underwent surgery between 2014 and 2019 at Hue Central Hospital, Vietnam. We investigated histopathological characteristics and immunohistochemical findings of all patients.Results:The average age was 55.9 ± 11.9 years. A tumor size of 2-5 cm accounted for 64.1%. The most common position was at the stomach which accounted for 48.5%. Among the subtypes of GIST, spindle cells were seen in 85.9% of patie...