Philip Measor - Academia.edu (original) (raw)

Papers by Philip Measor

Research paper thumbnail of A 3D printed microfluidic PCR device towards detecting SARS-CoV-2

Optical Diagnostics and Sensing XXIII: Toward Point-of-Care Diagnostics, Mar 16, 2023

Research paper thumbnail of A low-loss 3D printed ridge waveguide via stereolithography

Integrated Optics: Devices, Materials, and Technologies XXVI, 2022

Research paper thumbnail of A biocompatible 3D printed microfluidic C. elegans analysis device

Microfluidics, BioMEMS, and Medical Microsystems XX, 2022

A 3D printed microfluidic device for Caenorhabditis elegans analysis. The biocompatibility of the... more A 3D printed microfluidic device for Caenorhabditis elegans analysis. The biocompatibility of the 3D printed poly(ethylene glycol) diacrylate hydrogel resin was conducted and had no observable effect on worm lifespans. Worm organ morphology was directly observable through the microfluidic device and low autofluorescence was demonstrated using genetically-modified pharynx fluorescent worms.

Research paper thumbnail of Refractive index and dispersion of transparent 3D printing photoresins

Optical Materials Express, 2021

The refractive index of commonly used 3D printing photosensitive resins were measured across the ... more The refractive index of commonly used 3D printing photosensitive resins were measured across the visible spectrum for s- and p-polarized light for the first time. Commercially available resins (Monoprice Clear and formlabs Clear) and a custom polyethylene glycol diacrylate photopolymer resin was characterized using a critical angle determination method with a Pulfrich-based refractometer setup. The refractive indices ranged between 1.505 − 1.533 across the visible spectrum (670 − 405 nm, respectively), while the Abbe number ranged between 44.4 − 67.8.

Research paper thumbnail of Single-molecule optofluidics using liquid-core ARROW waveguides

2006 Digest of the LEOS Summer Topical Meetings

ABSTRACT

Research paper thumbnail of Optofluidic devices for on-chip optical filtering, sensing, and manipulation

Research paper thumbnail of An Ultrasensitive Optofluidic Nucleic Acid Biosensor

Conference on Lasers and Electro-Optics 2012, 2012

ABSTRACT Amplification-free nucleic acid testing using molecular beacon detection on an optofluid... more ABSTRACT Amplification-free nucleic acid testing using molecular beacon detection on an optofluidic chip is reported. A limit of detection at the single molecule detection level (10pM) and excellent specificity (single nucleotide mismatches) is observed.

Research paper thumbnail of Single-Particle Spectroscopy and Manipulation in Optofluidic Devices

Frontiers in Optics 2010/Laser Science XXVI, 2010

We review the state of the art of planar optofluidic devices using liquid-core waveguides for ult... more We review the state of the art of planar optofluidic devices using liquid-core waveguides for ultrasensitive particle detection and manipulation.

Research paper thumbnail of Loss Determination of Hollow-Core Waveguides by Optically-Induced Particle Transport

Frontiers in Optics 2007/Laser Science XXIII/Organic Materials and Devices for Displays and Energy Conversion, 2007

ABSTRACT

Research paper thumbnail of Integrated ARROW Waveguides for Molecule Specific Surface-enhanced Raman Sensing

2006 16th Biennial University/Government/Industry Microelectronics Symposium, 2006

ABSTRACT

Research paper thumbnail of Two-Beam Optical Trap in a Waveguide

Frontiers in Optics 2007/Laser Science XXIII/Organic Materials and Devices for Displays and Energy Conversion, 2007

ABSTRACT

Research paper thumbnail of Planar Electro-Optofluidic Chip: Integration of Nanopore with Optofluidics

Conference on Lasers and Electro-Optics 2010, 2010

Page 1. Planar Electro-optofluidic Chip: Integration of Nanopore with Optofluidics MI Rudenko1, M... more Page 1. Planar Electro-optofluidic Chip: Integration of Nanopore with Optofluidics MI Rudenko1, MR Holmes2, P. Measor1, DW Deamer1, AR Hawkins2, and H. Schmidt1 1School of Engineering, University of California, Santa Cruz. ...

Research paper thumbnail of Nanopore Fabrication in Hollow Integrated Waveguides

Advances in Optical Sciences Congress, 2009

Page 1. Nanopore Fabrication in Hollow Integrated Waveguides Matthew R. Holmes1, Mikhail Rudenko2... more Page 1. Nanopore Fabrication in Hollow Integrated Waveguides Matthew R. Holmes1, Mikhail Rudenko2, Philip Measor2, Tao Shang1, Holger Schmidt2, Aaron R. Hawkins1* 1ECE Department, Brigham Young University, 459 ...

Research paper thumbnail of <title>Hollow waveguide optimization for fluorescence based detection</title>

Advanced Fabrication Technologies for Micro/Nano Optics and Photonics, 2008

Previously, we created antiresonant reflecting optical waveguides (ARROWs) with hollow cores that... more Previously, we created antiresonant reflecting optical waveguides (ARROWs) with hollow cores that guide light through gas and liquid media. We have demonstrated that these ARROWs can be used in sensing applications with single particle sensitivity using fluorescence correlation spectroscopy. To increase sensitivity for single molecule sensing, we have improved our initial designs and fabrication methods to decrease ARROW background fluorescence

Research paper thumbnail of Integrated liquid-core ARROW waveguides for surface-enhanced Raman scattering

2006 Conference on Lasers and Electro-Optics and 2006 Quantum Electronics and Laser Science Conference, 2006

Integrated liquid-core ARROW waveguides for surface- ... Philip Measor, Dongliang Yin, and Holger... more Integrated liquid-core ARROW waveguides for surface- ... Philip Measor, Dongliang Yin, and Holger Schmidt School of Engineering, University of CA Santa Cruz, 1156 High Street, Santa Cruz, CA 95064 pmeasor@soe.ucsc.edu, (831) 459-5298 ... Leo Seballos and Jin Zhang ...

Research paper thumbnail of Characterization of optofluidic ARROW rejection filter devices

2008 Digest of the IEEE/LEOS Summer Topical Meetings, 2008

Optofluidic waveguides show great promise towards integrated microfluidic platforms with highly s... more Optofluidic waveguides show great promise towards integrated microfluidic platforms with highly sensitive sensing in liquid environments [1]. In particular, antiresonant reflecting optical waveguides (ARROWs) promise a standard Si microfabrication process with single-molecule ...

Research paper thumbnail of Optofluidic Platform Advancements for Optical Particle Manipulation

Conference on Lasers and Electro-Optics/International Quantum Electronics Conference, 2009

Abstract A new design mitigates multimode waveguide behavior in an optofluidic platform and incre... more Abstract A new design mitigates multimode waveguide behavior in an optofluidic platform and increases fundamental mode coupling to 95%. Experimental results yield excellent agreement with simulations and demonstrate a suitable device for optical particle ...

Research paper thumbnail of Active Trapping of Individual Particles on an Optofluidic Analysis Platform

Conference on Lasers and Electro-Optics/International Quantum Electronics Conference, 2009

Abstract A feedback-based opto-electrical trap is demonstrated on a fully planar optofluidic anal... more Abstract A feedback-based opto-electrical trap is demonstrated on a fully planar optofluidic analysis platform. The trap permits the prolonged observation of single fluorescent objects ranging from bacteria to nanoparticles in an optofluidic setting.

Research paper thumbnail of Selective Deposition of Thin Films for Integrated Notch Filters in Optofluidic Sensors

Frontiers in Optics 2009/Laser Science XXV/Fall 2009 OSA Optics & Photonics Technical Digest, 2009

ABSTRACT

Research paper thumbnail of Improving solid to hollow core transmission for integrated ARROW waveguides

Optics Express, 2008

Optical sensing platforms based on anti-resonant reflecting optical waveguides (ARROWs) with holl... more Optical sensing platforms based on anti-resonant reflecting optical waveguides (ARROWs) with hollow cores have been used for bioanalysis and atomic spectroscopy. These integrated platforms require that hollow waveguides interface with standard solid waveguides on the substrate to couple light into and out of test media. Previous designs required light at these interfaces to pass through the anti-resonant layers. We present a new ARROW design which coats the top and sides of the hollow core with only SiO 2 , allowing for high interface transmission between solid and hollow waveguides. The improvement in interface transmission with this design is demonstrated experimentally and increases from 35% to 79%. Given these parameters, higher optical throughputs are possible using single SiO 2 coatings when hollow waveguides are shorter than 5.8 mm.

Research paper thumbnail of A 3D printed microfluidic PCR device towards detecting SARS-CoV-2

Optical Diagnostics and Sensing XXIII: Toward Point-of-Care Diagnostics, Mar 16, 2023

Research paper thumbnail of A low-loss 3D printed ridge waveguide via stereolithography

Integrated Optics: Devices, Materials, and Technologies XXVI, 2022

Research paper thumbnail of A biocompatible 3D printed microfluidic C. elegans analysis device

Microfluidics, BioMEMS, and Medical Microsystems XX, 2022

A 3D printed microfluidic device for Caenorhabditis elegans analysis. The biocompatibility of the... more A 3D printed microfluidic device for Caenorhabditis elegans analysis. The biocompatibility of the 3D printed poly(ethylene glycol) diacrylate hydrogel resin was conducted and had no observable effect on worm lifespans. Worm organ morphology was directly observable through the microfluidic device and low autofluorescence was demonstrated using genetically-modified pharynx fluorescent worms.

Research paper thumbnail of Refractive index and dispersion of transparent 3D printing photoresins

Optical Materials Express, 2021

The refractive index of commonly used 3D printing photosensitive resins were measured across the ... more The refractive index of commonly used 3D printing photosensitive resins were measured across the visible spectrum for s- and p-polarized light for the first time. Commercially available resins (Monoprice Clear and formlabs Clear) and a custom polyethylene glycol diacrylate photopolymer resin was characterized using a critical angle determination method with a Pulfrich-based refractometer setup. The refractive indices ranged between 1.505 − 1.533 across the visible spectrum (670 − 405 nm, respectively), while the Abbe number ranged between 44.4 − 67.8.

Research paper thumbnail of Single-molecule optofluidics using liquid-core ARROW waveguides

2006 Digest of the LEOS Summer Topical Meetings

ABSTRACT

Research paper thumbnail of Optofluidic devices for on-chip optical filtering, sensing, and manipulation

Research paper thumbnail of An Ultrasensitive Optofluidic Nucleic Acid Biosensor

Conference on Lasers and Electro-Optics 2012, 2012

ABSTRACT Amplification-free nucleic acid testing using molecular beacon detection on an optofluid... more ABSTRACT Amplification-free nucleic acid testing using molecular beacon detection on an optofluidic chip is reported. A limit of detection at the single molecule detection level (10pM) and excellent specificity (single nucleotide mismatches) is observed.

Research paper thumbnail of Single-Particle Spectroscopy and Manipulation in Optofluidic Devices

Frontiers in Optics 2010/Laser Science XXVI, 2010

We review the state of the art of planar optofluidic devices using liquid-core waveguides for ult... more We review the state of the art of planar optofluidic devices using liquid-core waveguides for ultrasensitive particle detection and manipulation.

Research paper thumbnail of Loss Determination of Hollow-Core Waveguides by Optically-Induced Particle Transport

Frontiers in Optics 2007/Laser Science XXIII/Organic Materials and Devices for Displays and Energy Conversion, 2007

ABSTRACT

Research paper thumbnail of Integrated ARROW Waveguides for Molecule Specific Surface-enhanced Raman Sensing

2006 16th Biennial University/Government/Industry Microelectronics Symposium, 2006

ABSTRACT

Research paper thumbnail of Two-Beam Optical Trap in a Waveguide

Frontiers in Optics 2007/Laser Science XXIII/Organic Materials and Devices for Displays and Energy Conversion, 2007

ABSTRACT

Research paper thumbnail of Planar Electro-Optofluidic Chip: Integration of Nanopore with Optofluidics

Conference on Lasers and Electro-Optics 2010, 2010

Page 1. Planar Electro-optofluidic Chip: Integration of Nanopore with Optofluidics MI Rudenko1, M... more Page 1. Planar Electro-optofluidic Chip: Integration of Nanopore with Optofluidics MI Rudenko1, MR Holmes2, P. Measor1, DW Deamer1, AR Hawkins2, and H. Schmidt1 1School of Engineering, University of California, Santa Cruz. ...

Research paper thumbnail of Nanopore Fabrication in Hollow Integrated Waveguides

Advances in Optical Sciences Congress, 2009

Page 1. Nanopore Fabrication in Hollow Integrated Waveguides Matthew R. Holmes1, Mikhail Rudenko2... more Page 1. Nanopore Fabrication in Hollow Integrated Waveguides Matthew R. Holmes1, Mikhail Rudenko2, Philip Measor2, Tao Shang1, Holger Schmidt2, Aaron R. Hawkins1* 1ECE Department, Brigham Young University, 459 ...

Research paper thumbnail of <title>Hollow waveguide optimization for fluorescence based detection</title>

Advanced Fabrication Technologies for Micro/Nano Optics and Photonics, 2008

Previously, we created antiresonant reflecting optical waveguides (ARROWs) with hollow cores that... more Previously, we created antiresonant reflecting optical waveguides (ARROWs) with hollow cores that guide light through gas and liquid media. We have demonstrated that these ARROWs can be used in sensing applications with single particle sensitivity using fluorescence correlation spectroscopy. To increase sensitivity for single molecule sensing, we have improved our initial designs and fabrication methods to decrease ARROW background fluorescence

Research paper thumbnail of Integrated liquid-core ARROW waveguides for surface-enhanced Raman scattering

2006 Conference on Lasers and Electro-Optics and 2006 Quantum Electronics and Laser Science Conference, 2006

Integrated liquid-core ARROW waveguides for surface- ... Philip Measor, Dongliang Yin, and Holger... more Integrated liquid-core ARROW waveguides for surface- ... Philip Measor, Dongliang Yin, and Holger Schmidt School of Engineering, University of CA Santa Cruz, 1156 High Street, Santa Cruz, CA 95064 pmeasor@soe.ucsc.edu, (831) 459-5298 ... Leo Seballos and Jin Zhang ...

Research paper thumbnail of Characterization of optofluidic ARROW rejection filter devices

2008 Digest of the IEEE/LEOS Summer Topical Meetings, 2008

Optofluidic waveguides show great promise towards integrated microfluidic platforms with highly s... more Optofluidic waveguides show great promise towards integrated microfluidic platforms with highly sensitive sensing in liquid environments [1]. In particular, antiresonant reflecting optical waveguides (ARROWs) promise a standard Si microfabrication process with single-molecule ...

Research paper thumbnail of Optofluidic Platform Advancements for Optical Particle Manipulation

Conference on Lasers and Electro-Optics/International Quantum Electronics Conference, 2009

Abstract A new design mitigates multimode waveguide behavior in an optofluidic platform and incre... more Abstract A new design mitigates multimode waveguide behavior in an optofluidic platform and increases fundamental mode coupling to 95%. Experimental results yield excellent agreement with simulations and demonstrate a suitable device for optical particle ...

Research paper thumbnail of Active Trapping of Individual Particles on an Optofluidic Analysis Platform

Conference on Lasers and Electro-Optics/International Quantum Electronics Conference, 2009

Abstract A feedback-based opto-electrical trap is demonstrated on a fully planar optofluidic anal... more Abstract A feedback-based opto-electrical trap is demonstrated on a fully planar optofluidic analysis platform. The trap permits the prolonged observation of single fluorescent objects ranging from bacteria to nanoparticles in an optofluidic setting.

Research paper thumbnail of Selective Deposition of Thin Films for Integrated Notch Filters in Optofluidic Sensors

Frontiers in Optics 2009/Laser Science XXV/Fall 2009 OSA Optics & Photonics Technical Digest, 2009

ABSTRACT

Research paper thumbnail of Improving solid to hollow core transmission for integrated ARROW waveguides

Optics Express, 2008

Optical sensing platforms based on anti-resonant reflecting optical waveguides (ARROWs) with holl... more Optical sensing platforms based on anti-resonant reflecting optical waveguides (ARROWs) with hollow cores have been used for bioanalysis and atomic spectroscopy. These integrated platforms require that hollow waveguides interface with standard solid waveguides on the substrate to couple light into and out of test media. Previous designs required light at these interfaces to pass through the anti-resonant layers. We present a new ARROW design which coats the top and sides of the hollow core with only SiO 2 , allowing for high interface transmission between solid and hollow waveguides. The improvement in interface transmission with this design is demonstrated experimentally and increases from 35% to 79%. Given these parameters, higher optical throughputs are possible using single SiO 2 coatings when hollow waveguides are shorter than 5.8 mm.