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Papers by Piet Vanhoenacker
Neuropathology and Applied Neurobiology
Journal of the Belgian Society of Radiology
Journal of the Belgian Society of Radiology, 2022
Journal of the Belgian Society of Radiology
Different times call for different measures. The COVID-19 pandemic has forced us to search for al... more Different times call for different measures. The COVID-19 pandemic has forced us to search for alternative methods to provide an equally qualitative and interesting annual meeting. For the Belgian Society of Radiology (BSR) 2020 Annual Meeting, the sections on Abdominal Imaging, Thoracic Imaging, and the Young Radiologist Section (YRS) joined forces to organize a meeting that is quite different from the ones we have organized in the past. We have chosen to create a compact-approximately 5 hours-and entirely virtual meeting with the possibility of live interaction with the speakers during the question-and-answer sessions. The meeting kicks off with a message from the BSR president about radiology in 2020, followed by three abdominal talks. The second session combines an abdominal talk with COVID-related talks. We have chosen to include not only thoracic findings in COVID-19, but to take it further and discuss neurological patterns, long-term clinical findings, and the progress in artificial intelligence in COVID-19. Lastly, the annual meeting closes off with a short movie about the (re)discovery of Röntgens X-ray, presented to us by the
JBR-BTR : organe de la Société royale belge de radiologie (SRBR) = orgaan van de Koninklijke Belgische Vereniging voor Radiologie (KBVR), 2001
Journal of the Belgian Society of Radiology, 2011
Poster: "ESCR 2014 / 421 / Is Beta-blockade necessary to obtain diagnostic image quality at ... more Poster: "ESCR 2014 / 421 / Is Beta-blockade necessary to obtain diagnostic image quality at low radiation dose of coronary CT angiography using a 2nd generation 320-row scanner? " by: " O. Ghekiere 1, J. Djekic1, M. El Hachemi1, D. Hansen2, A.-S. Vanhoenacker3, P. Dendale2, A. Nchimi Longang1; 1Liege/BE, 2Hasselt/BE, 3Aalst/BE"
Journal of the Belgian Society of Radiology, 2021
EuroIntervention, 2008
To assess plaque characteristics by multi-detector computed tomography angiography in patients wi... more To assess plaque characteristics by multi-detector computed tomography angiography in patients with known coronary artery disease and to compare these findings with those obtained with intravascular ultrasound-derived radiofrequency analysis of plaque composition. By computed tomography, lesions were classified on the basis of Hounsfield Units as non-calcified, calcified, or mixed. By intravascular ultrasound-derived radiofrequency analysis, plaques were classified according to the relative composition of components with specific backscatter characteristics (necrotic core, fibrous, fibro-fatty, calcium). Thin cap fibroatheroma (defined as necrotic core component >10% without evidence of fibrotic cap, calcium >5%, remodelling index >1.05) was considered as vulnerable plaque. Seventy-eight plaques were analysed. By computed tomography, 22 plaques were classified as non-calcified and 56 as mixed. A higher incidence of mixed plaques was observed among lesions causing unstable a...
Journal of the Belgian Society of Radiology
Dear colleagues, This year's edition of the annual BSR meeting will definitely be a special one. ... more Dear colleagues, This year's edition of the annual BSR meeting will definitely be a special one. Due to the COVID-19 pandemic, we decided to offer a virtual-only meeting. The program will consist of a fascinating mix of lectures on abdominal imaging and of course COVID-19 imaging and its practical implications. I am happy to take the opportunity to thank Professor Raymond Oyen, president of the Scientific Council, and Drs. Anne-Sophie Vanhoenacker and Flavien Grandjean, presidents of the Young Radiologist Section, and all others involved in the organization of this Annual Meeting. Since the pandemic, paradigms for continuing education and scientific gatherings are subjected to a disruptive trend,
Journal of the Belgian Society of Radiology
Research article Multidetector computed tomography angiography for assessment of in-stent resteno... more Research article Multidetector computed tomography angiography for assessment of in-stent restenosis: meta-analysis of diagnostic performance
BMC Medical Imaging, 2008
Background: Multi-detector computed tomography angiography (MDCTA)of the coronary arteries after ... more Background: Multi-detector computed tomography angiography (MDCTA)of the coronary arteries after stenting has been evaluated in multiple studies. The purpose of this study was to perform a structured review and meta-analysis of the diagnostic performance of MDCTA for the detection of in-stent restenosis in the coronary arteries. Methods: A Pubmed and manual search of the literature on in-stent restenosis (ISR) detected on MDCTA compared with conventional coronary angiography (CA) was performed. Bivariate summary receiver operating curve (SROC) analysis, with calculation of summary estimates was done on a stent and patient basis. In addition, the influence of study characteristics on diagnostic performance and number of non-assessable segments (NAP) was investigated with logistic metaregression. Results: Fourteen studies were included. On a stent basis, Pooled sensitivity and specificity were 0.82(0.72-0.89) and 0.91 (0.83-0.96). Pooled negative likelihood ratio and positive likelihood ratio were 0.20 (0.13-0.32) and 9.34 (4.68-18.62) respectively. The exclusion of non-assessable stents and the strut thickness of the stents had an influence on the diagnostic performance. The proportion of non-assessable stents was influenced by the number of detectors, stent diameter, strut thickness and the use of an edge-enhancing kernel. Conclusion: The sensitivity of MDTCA for the detection of in-stent stenosis is insufficient to use this test to select patients for further invasive testing as with this strategy around 20% of the patients with in-stent stenosis would be missed. Further improvement of scanner technology is needed before it can be recommended as a triage instrument in practice. In addition, the number of non-assessable stents is also high.
Open Heart
ObjectivesCT coronary angiography (CTCA) has become a valuable diagnostic test in the workup of p... more ObjectivesCT coronary angiography (CTCA) has become a valuable diagnostic test in the workup of patients with possible coronary artery disease (CAD). Because of inherent limitations in spatial resolution, epicardial vessels with a small diameter, in general less than 1.5–2 mm, have so far been excluded in studies assessing clinical utility of CTCA. This study sought to assess the clinical impact of CTCA taking into account pathology in small coronary arteries.MethodsWe conducted a retrospective cohort study of all patients with possible CAD who underwent dual-source CTCA and subsequent invasive coronary angiography (ICA) between January 2010 and July 2017. Patients with an Agatston calcium score ≥1000 were reported separately. Diagnostic accuracy of CTCA on a patient, vessel and segment level was calculated. The physician’s therapeutic decision was defined as conservative, medical antianginal treatment or revascularisation. Using ICA as the reference, we calculated the precision of ...
American Journal of Roentgenology
flow reserve-that is, the ratio of hyperemic flow in a stenotic coronary artery to the hyperemic ... more flow reserve-that is, the ratio of hyperemic flow in a stenotic coronary artery to the hyperemic flow in a normal coronary artery. Therefore, it standardizes inflow conditions, avoiding the confounding effects of microvascular disease and collateral flow [1-4]. Cardiac stress perfusion MRI assesses noninvasively the myocardial vascular sup
Journal of the Belgian Society of Radiology
In Belgium, there has always been a strong tradition to foster radiology and imaging research. Th... more In Belgium, there has always been a strong tradition to foster radiology and imaging research. The former Royal Belgian Society of Radiology (RBSR-KBVR-SRBR)-after the merger with the Consilium and NUR, now the Belgian Society of Radiology (BSR-BVR-SBR)-has persistently been one of the driving forces of support to individuals who wanted to innovate and put Belgian radiology research at the forefront.
The British journal of radiology, 2017
Multidetector CT angiography (CTA) has become a widely accepted examination for non-invasive eval... more Multidetector CT angiography (CTA) has become a widely accepted examination for non-invasive evaluation of the heart and coronary arteries. Despite its ongoing success and worldwide clinical implementation, it remains an often-challenging procedure in which image quality, and hence diagnostic value, is determined by both technical and patient-related factors. Thorough knowledge of these factors is important to obtain high-quality examinations. In this review, we discuss several key elements that may adversely affect coronary CTA image quality as well as potential measures that can be taken to mitigate their impact. In addition, several recent vendor-specific advances and future directions to improve image quality are discussed.
Neuropathology and Applied Neurobiology
Journal of the Belgian Society of Radiology
Journal of the Belgian Society of Radiology, 2022
Journal of the Belgian Society of Radiology
Different times call for different measures. The COVID-19 pandemic has forced us to search for al... more Different times call for different measures. The COVID-19 pandemic has forced us to search for alternative methods to provide an equally qualitative and interesting annual meeting. For the Belgian Society of Radiology (BSR) 2020 Annual Meeting, the sections on Abdominal Imaging, Thoracic Imaging, and the Young Radiologist Section (YRS) joined forces to organize a meeting that is quite different from the ones we have organized in the past. We have chosen to create a compact-approximately 5 hours-and entirely virtual meeting with the possibility of live interaction with the speakers during the question-and-answer sessions. The meeting kicks off with a message from the BSR president about radiology in 2020, followed by three abdominal talks. The second session combines an abdominal talk with COVID-related talks. We have chosen to include not only thoracic findings in COVID-19, but to take it further and discuss neurological patterns, long-term clinical findings, and the progress in artificial intelligence in COVID-19. Lastly, the annual meeting closes off with a short movie about the (re)discovery of Röntgens X-ray, presented to us by the
JBR-BTR : organe de la Société royale belge de radiologie (SRBR) = orgaan van de Koninklijke Belgische Vereniging voor Radiologie (KBVR), 2001
Journal of the Belgian Society of Radiology, 2011
Poster: "ESCR 2014 / 421 / Is Beta-blockade necessary to obtain diagnostic image quality at ... more Poster: "ESCR 2014 / 421 / Is Beta-blockade necessary to obtain diagnostic image quality at low radiation dose of coronary CT angiography using a 2nd generation 320-row scanner? " by: " O. Ghekiere 1, J. Djekic1, M. El Hachemi1, D. Hansen2, A.-S. Vanhoenacker3, P. Dendale2, A. Nchimi Longang1; 1Liege/BE, 2Hasselt/BE, 3Aalst/BE"
Journal of the Belgian Society of Radiology, 2021
EuroIntervention, 2008
To assess plaque characteristics by multi-detector computed tomography angiography in patients wi... more To assess plaque characteristics by multi-detector computed tomography angiography in patients with known coronary artery disease and to compare these findings with those obtained with intravascular ultrasound-derived radiofrequency analysis of plaque composition. By computed tomography, lesions were classified on the basis of Hounsfield Units as non-calcified, calcified, or mixed. By intravascular ultrasound-derived radiofrequency analysis, plaques were classified according to the relative composition of components with specific backscatter characteristics (necrotic core, fibrous, fibro-fatty, calcium). Thin cap fibroatheroma (defined as necrotic core component >10% without evidence of fibrotic cap, calcium >5%, remodelling index >1.05) was considered as vulnerable plaque. Seventy-eight plaques were analysed. By computed tomography, 22 plaques were classified as non-calcified and 56 as mixed. A higher incidence of mixed plaques was observed among lesions causing unstable a...
Journal of the Belgian Society of Radiology
Dear colleagues, This year's edition of the annual BSR meeting will definitely be a special one. ... more Dear colleagues, This year's edition of the annual BSR meeting will definitely be a special one. Due to the COVID-19 pandemic, we decided to offer a virtual-only meeting. The program will consist of a fascinating mix of lectures on abdominal imaging and of course COVID-19 imaging and its practical implications. I am happy to take the opportunity to thank Professor Raymond Oyen, president of the Scientific Council, and Drs. Anne-Sophie Vanhoenacker and Flavien Grandjean, presidents of the Young Radiologist Section, and all others involved in the organization of this Annual Meeting. Since the pandemic, paradigms for continuing education and scientific gatherings are subjected to a disruptive trend,
Journal of the Belgian Society of Radiology
Research article Multidetector computed tomography angiography for assessment of in-stent resteno... more Research article Multidetector computed tomography angiography for assessment of in-stent restenosis: meta-analysis of diagnostic performance
BMC Medical Imaging, 2008
Background: Multi-detector computed tomography angiography (MDCTA)of the coronary arteries after ... more Background: Multi-detector computed tomography angiography (MDCTA)of the coronary arteries after stenting has been evaluated in multiple studies. The purpose of this study was to perform a structured review and meta-analysis of the diagnostic performance of MDCTA for the detection of in-stent restenosis in the coronary arteries. Methods: A Pubmed and manual search of the literature on in-stent restenosis (ISR) detected on MDCTA compared with conventional coronary angiography (CA) was performed. Bivariate summary receiver operating curve (SROC) analysis, with calculation of summary estimates was done on a stent and patient basis. In addition, the influence of study characteristics on diagnostic performance and number of non-assessable segments (NAP) was investigated with logistic metaregression. Results: Fourteen studies were included. On a stent basis, Pooled sensitivity and specificity were 0.82(0.72-0.89) and 0.91 (0.83-0.96). Pooled negative likelihood ratio and positive likelihood ratio were 0.20 (0.13-0.32) and 9.34 (4.68-18.62) respectively. The exclusion of non-assessable stents and the strut thickness of the stents had an influence on the diagnostic performance. The proportion of non-assessable stents was influenced by the number of detectors, stent diameter, strut thickness and the use of an edge-enhancing kernel. Conclusion: The sensitivity of MDTCA for the detection of in-stent stenosis is insufficient to use this test to select patients for further invasive testing as with this strategy around 20% of the patients with in-stent stenosis would be missed. Further improvement of scanner technology is needed before it can be recommended as a triage instrument in practice. In addition, the number of non-assessable stents is also high.
Open Heart
ObjectivesCT coronary angiography (CTCA) has become a valuable diagnostic test in the workup of p... more ObjectivesCT coronary angiography (CTCA) has become a valuable diagnostic test in the workup of patients with possible coronary artery disease (CAD). Because of inherent limitations in spatial resolution, epicardial vessels with a small diameter, in general less than 1.5–2 mm, have so far been excluded in studies assessing clinical utility of CTCA. This study sought to assess the clinical impact of CTCA taking into account pathology in small coronary arteries.MethodsWe conducted a retrospective cohort study of all patients with possible CAD who underwent dual-source CTCA and subsequent invasive coronary angiography (ICA) between January 2010 and July 2017. Patients with an Agatston calcium score ≥1000 were reported separately. Diagnostic accuracy of CTCA on a patient, vessel and segment level was calculated. The physician’s therapeutic decision was defined as conservative, medical antianginal treatment or revascularisation. Using ICA as the reference, we calculated the precision of ...
American Journal of Roentgenology
flow reserve-that is, the ratio of hyperemic flow in a stenotic coronary artery to the hyperemic ... more flow reserve-that is, the ratio of hyperemic flow in a stenotic coronary artery to the hyperemic flow in a normal coronary artery. Therefore, it standardizes inflow conditions, avoiding the confounding effects of microvascular disease and collateral flow [1-4]. Cardiac stress perfusion MRI assesses noninvasively the myocardial vascular sup
Journal of the Belgian Society of Radiology
In Belgium, there has always been a strong tradition to foster radiology and imaging research. Th... more In Belgium, there has always been a strong tradition to foster radiology and imaging research. The former Royal Belgian Society of Radiology (RBSR-KBVR-SRBR)-after the merger with the Consilium and NUR, now the Belgian Society of Radiology (BSR-BVR-SBR)-has persistently been one of the driving forces of support to individuals who wanted to innovate and put Belgian radiology research at the forefront.
The British journal of radiology, 2017
Multidetector CT angiography (CTA) has become a widely accepted examination for non-invasive eval... more Multidetector CT angiography (CTA) has become a widely accepted examination for non-invasive evaluation of the heart and coronary arteries. Despite its ongoing success and worldwide clinical implementation, it remains an often-challenging procedure in which image quality, and hence diagnostic value, is determined by both technical and patient-related factors. Thorough knowledge of these factors is important to obtain high-quality examinations. In this review, we discuss several key elements that may adversely affect coronary CTA image quality as well as potential measures that can be taken to mitigate their impact. In addition, several recent vendor-specific advances and future directions to improve image quality are discussed.