Prasanna Thomas - Academia.edu (original) (raw)

Prasanna Thomas

Pulmonologist who wants to spread healing and concern to people in need.very interested in socially relevant issues

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Research paper thumbnail of Challenges in diagnosing Sarcoidosis in tuberculosis endemic regions: Clinical scenario in India

Sarcoidosis, vasculitis, and diffuse lung diseases : official journal of WASOG, Jan 23, 2016

Sarcoidosis is a chronic, systemic disease of unknown etiology that affects multiple organs. The... more Sarcoidosis is a chronic, systemic disease of unknown etiology that affects multiple organs. The disease was considered rare in developing countries like India. More recently sarcoidosis is being increasingly diagnosed in countries where tuberculosis continues to be endemic. There is a general perception among physicians that the prevalence of sarcoidosis has increased over the last two decades in countries like India. This may be true but could also be related to better awareness of the condition, availability of improved diagnostic facilities and the increased ability of physicians to differentiate it from tuberculosis. In India, diagnosis of tuberculosis is entertained first in patients who may have sarcoidosis and thus, it is very likely for sarcoidosis to be misdiagnosed as tuberculosis, owing to the high prevalence of tuberculosis and clinicoradiological resemblance to the disease. This editorial highlights the challenges in diagnosing tuberculosis in countries where tubercul...

Research paper thumbnail of Fluticasone/Formoterol compared withother ICS/LABAs in asthma: A systematic review

BackgroundAn ICS-LABA combination has become the standard of care in asthma. Various ICS-LABAs ar... more BackgroundAn ICS-LABA combination has become the standard of care in asthma. Various ICS-LABAs are commercially available providing the clinician with many choices. A thorough understanding of the clinical efficacy and safety of various formulations will immensely benefit the prescribing doctor to decide the choice of agent. The present review compares the clinical efficacy and safety of formoterol fluticasone (FF) to other ICS/LABA combinations in asthmatics.MethodsThe review adhered to the general principles mentioned in the CRD guidance and the PRISMA statement. We searched Medline, Embase, and Cochrane Controlled Trials Register databases on the efficacy of FF in treating asthma compared with other ICS-LABAs. A total of 138 trials identified initially. Only trials comparing the efficacy and safety of FF in comparision with Salmeterol/fluticasone (SF) or Budesonide/Formoterol (BF) were selected. The outcomes compared were onset of bronchodilator action, improvement in lung functi...

Research paper thumbnail of Challenges in diagnosing Sarcoidosis in tuberculosis endemic regions: Clinical scenario in India

Sarcoidosis, vasculitis, and diffuse lung diseases : official journal of WASOG, Jan 23, 2016

Sarcoidosis is a chronic, systemic disease of unknown etiology that affects multiple organs. The... more Sarcoidosis is a chronic, systemic disease of unknown etiology that affects multiple organs. The disease was considered rare in developing countries like India. More recently sarcoidosis is being increasingly diagnosed in countries where tuberculosis continues to be endemic. There is a general perception among physicians that the prevalence of sarcoidosis has increased over the last two decades in countries like India. This may be true but could also be related to better awareness of the condition, availability of improved diagnostic facilities and the increased ability of physicians to differentiate it from tuberculosis. In India, diagnosis of tuberculosis is entertained first in patients who may have sarcoidosis and thus, it is very likely for sarcoidosis to be misdiagnosed as tuberculosis, owing to the high prevalence of tuberculosis and clinicoradiological resemblance to the disease. This editorial highlights the challenges in diagnosing tuberculosis in countries where tubercul...

Research paper thumbnail of Fluticasone/Formoterol compared withother ICS/LABAs in asthma: A systematic review

BackgroundAn ICS-LABA combination has become the standard of care in asthma. Various ICS-LABAs ar... more BackgroundAn ICS-LABA combination has become the standard of care in asthma. Various ICS-LABAs are commercially available providing the clinician with many choices. A thorough understanding of the clinical efficacy and safety of various formulations will immensely benefit the prescribing doctor to decide the choice of agent. The present review compares the clinical efficacy and safety of formoterol fluticasone (FF) to other ICS/LABA combinations in asthmatics.MethodsThe review adhered to the general principles mentioned in the CRD guidance and the PRISMA statement. We searched Medline, Embase, and Cochrane Controlled Trials Register databases on the efficacy of FF in treating asthma compared with other ICS-LABAs. A total of 138 trials identified initially. Only trials comparing the efficacy and safety of FF in comparision with Salmeterol/fluticasone (SF) or Budesonide/Formoterol (BF) were selected. The outcomes compared were onset of bronchodilator action, improvement in lung functi...

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