Prashant Gaikwad - Academia.edu (original) (raw)

Papers by Prashant Gaikwad

Journal of the Endocrine Society

Background Pseudohypoparathyroidism (PHP) is a heterogeneous group of disorders in which resistan... more Background Pseudohypoparathyroidism (PHP) is a heterogeneous group of disorders in which resistance to parathyroid hormone (PTH) in the proximal renal tubules leads to hypocalcemia, hyperphosphatemia, and impaired 1,25(OH)2 vitamin D production. Clinical Case A 2-month-old child presented with history of recurrent focal seizures since last 10 days. During the first episode, the child was treated with anti- convulsant by paediatrician. Five days later she again developed focal seizures, this time the child was evaluated and serum calcium was 5.6 mg/dl (normal, 8.6-10.2 mg/dl), phosphorus 7.5 mg/dL (normal, 4. 0-7. 0 mg/dL), and magnesium 2. 0 mg/dL (normal 1.8-2.4 mg/dL). In view of symptomatic hypocalcemia, she was treated with I. V. 10% calcium gluconate and oral calcifediol (800 IU/day). The child was seizure free but still had hypocalcemia - serum calcium-6.8 mg/dl, hence the child was evaluated further- serum PTH was 561 pg/mL (normal, 9-91 pg/mL), 25-hydroxyvitamin D was 54.1 n...

Journal of the Endocrine Society

Introduction Rathke's cleft cysts (RCC) are cystic sellar and suprasellar lesion derived from... more Introduction Rathke's cleft cysts (RCC) are cystic sellar and suprasellar lesion derived from remnant of Rathke's pouch. RCC are mainly asymptomatic, but can present with headache, visual disturbance, panhypopituitarism, hypothalamic dysfunction when it enlarges causing compression to the surrounding structure. Diabetes insipidus as a presenting feature of RCC is rare. Even it presents with diabetes insipidus, it occurs more in elderly. Clinical Case A 32-year-old married female, mother of one child, having normal menstrual cycle presented with polyuria, polydipsia of recent onset. Clinical examinations was normal. Serum creatinine, potassium, calcium, plasma glucose were within normal range. Anterior pituitary hormonal evaluation was normal. Serum sodium was in the upper range of normal. Basal urine osmolality and serum osmolality were 87.49 mosm/kg (150 -1150 mOsm/kg) and 287 mOsm/kg (275 -295 mOsm/kg) respectively. Water deprivation test followed by vasopressin challenge ...

Cureus

Graves' dermopathy is one of the extra-thyroidal manifestations of Graves' disease (GD) and is ch... more Graves' dermopathy is one of the extra-thyroidal manifestations of Graves' disease (GD) and is characterized by the accumulation of glycosaminoglycans in the reticular dermis. In the majority of cases, pretibial myxedema is self-limiting but, in some cases, it can lead to structural and functional damage. Topical steroids with occlusive dressing remain the conventional treatment, but intralesional steroids have shown promising results. We hereby present a case of pretibial myxedema treated successfully with intralesional triamcinolone acetate.

14th International Conference on Automotive User Interfaces and Interactive Vehicular Applications

Diabetes

Aims: To study the effect of Vitamin D replacement on glycaemic control and pregnancy outcomes in... more Aims: To study the effect of Vitamin D replacement on glycaemic control and pregnancy outcomes in Gestational Diabetes Mellitus patient with Vitamin D deficiency. Methods: In this prospective, open-label interventional study 60 GDM subjects with Vitamin D deficiency were divided into 2 groups of 30 each, and the intervention group received 60,000 IU of cholecalciferol weekly for 6 weeks and then monthly for the duration of pregnancy. while the control group did not. Vitamin D status was re-assessed at 32 weeks of gestation for both groups. The glycaemic status was assessed using fasting plasma glucose and 1-hour and 2-hour postprandial glucose at 30 weeks of gestation and at time of delivery. Feto-maternal outcomes: Time of delivery (weeks of gestation) , method of delivery, pre-eclampsia, still-birth, neonatal hypoglycaemia, neonatal jaundice, birth weight, head circumference of the baby, APGAR score at 5 minutes in both groups were also assessed. Results: In the intervention group...

Vasantrao Naik Marathwada Krishi Vidyapeeth, Parbhani, Aug 28, 2017

Journal of Physical Chemistry C, Jan 10, 2019

Strong, directional, N bonding led surface stabilization is induced to obtain free-standing two-d... more Strong, directional, N bonding led surface stabilization is induced to obtain free-standing two-dimensional (2D) layered assemblies of Lonsdaleite and diamond-phase carbon by surface termination at three coordinated C sites. These assemblies have strong bonding and surface N lone pair induced self-protection and achieve respective bulk-like electronic, mechanical, and crystallographic properties at as low as seven atomic layer thickness. Lonsdaleite phase subnano thickness free-standing as small as three layered assembly shows bulk-like thermal stability up to 2900 K. Size confinement effect dominates up to four layered assembly, and then electronic and crystallographic properties are dominated by bulk stabilization which saturates toward respective bulk-like features from seven layered assembly. Similarly, free-standing hybrid assemblies of Lonsdaleite phase carbon with BeF (C5NBeF) and BS (C5NBS) layer are also proposed along with low symmetric Cm-C3N4 layered assembly. The combination of N and O is sho...

Cureus, 2022

Juvenile granulosa cell tumor leading to isosexual peripheral precocious puberty is a well-known ... more Juvenile granulosa cell tumor leading to isosexual peripheral precocious puberty is a well-known association. Here, we report a rare case of central precocious puberty secondary to granulosa cell tumor of the ovary. A five-year and five-month-old girl presented with a history of progressive enlargement of bilateral breasts and intermittent vaginal spotting, associated with growth acceleration. Elevated estradiol and suppressed serum follicle-stimulating hormone were found on investigation. Additionally, abdominal and pelvic ultrasonography was suggestive of a right ovarian mass, which proved to be a juvenile granulosa cell tumor on histopathology and immunohistochemistry, leading to a diagnosis of peripheral precocious puberty secondary to granulosa cell tumor of the ovary. One and a half years after resection of the tumor, secondary sexual characteristics progressed with regression of tumor markers, and no mass was noted on ultrasonography, leading to the suspicion of central precocious puberty. Pubertal basal luteinizing hormone (LH) and elevated triptorelin-stimulated LH confirmed the diagnosis of central precocious puberty secondary to granulosa cell tumor of the ovary.

Investigation for M-40 grade of concrete having mix proportion 1:1.27:2.52 with water cement rati... more Investigation for M-40 grade of concrete having mix proportion 1:1.27:2.52 with water cement ratio 0.4 to study the compressive strength, flexural strength of steel fibre reinforced concrete (SFRC) containing fibers of 1% volume fraction of dramix fiber. A result data obtained has been analyzed and compared with a control specimen (0% fiber). Result data clearly shows percentage increase in 28 days Compressive strength, Flexural strength for M-40 Grade of Concrete.

An entry from the Inorganic Crystal Structure Database, the world's repository for inorganic ... more An entry from the Inorganic Crystal Structure Database, the world's repository for inorganic crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the joint CCDC and FIZ Karlsruhe Access Structures service and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.

Annals of Pathology and Laboratory Medicine, 2016

Background: The primary pediatric brain tumors (PBT) are the second most common cause of death du... more Background: The primary pediatric brain tumors (PBT) are the second most common cause of death due to malignancies in children. This study was done to analyze the histological spectrum of primary brain tumors in children and also to find out the epidemiology of the common pediatric brain tumors. Methods: Data regarding age, gender, topography, and histopathology of 239 pediatric patients (0–18 years) with brain tumors operated over a period of 15 years (January-2001 to December-2015) was collected and analyzed according to World Health Organization 2007 classification Result: PBTs were more common in males (54.8%) as compared to females (45.2%) with male to female ratio of 1.21:1. Frequency of tumors was higher in childhood age group (>5-<15 years) i.e. (55.6%) when compared to adolescent age group (15.9%). The most common anatomical site was cerebellum (40.5%), followed by hemispheres (21.4%). Supratentorial tumors (51.9%) were predominant than infratentorial tumors (45.2%) a...

arXiv: Materials Science, 2020

A new class of tetragonally symmetric 2D octagonal family of monolayers (o-MLs) has emerged recen... more A new class of tetragonally symmetric 2D octagonal family of monolayers (o-MLs) has emerged recently and demands understanding at the fundamental level. o-MLs of metal nitride and carbide family (BN, AlN, GaN, GeC, SiC) along with C and BP are computationally designed and their stability and electronic structure are investigated. These binary o-MLs show mixed ionic and covalent bonding with the hybridized p states dominating the electronic structure around the Fermi level. Geometric and structural similarity of o-C and o-BN has been exploited to form patterned hybrid o-MLs ranging from metallic to insulating phases. Stacking of zigzag buckled o-MLs results in stable body centered tetragonal (bct)-bulk phase that is suitable for most materials from group IV, III-V and II-VI. Vertically cut chunks of o-BN and o-C bulk or stacking of o-rings, unlike rolling of hexagonal (h)-ML, provide a plausible way to form very thin o-nanotubes (o-NT). Confined and bulk structures formed with an oct...

Scientific Reports, 2021

Yarrowia clade contains yeast species morphologically, ecologically, physiologically and genetica... more Yarrowia clade contains yeast species morphologically, ecologically, physiologically and genetically diverse in nature. Yarrowia lipolytica NCIM 3590 (NCIM 3590), a biotechnologically important strain, isolated from Scottish sea waters was reinvestigated for its phenotypic, biochemical, molecular and genomic properties as it exhibited characteristics unlike Y. lipolytica, namely, absence of extracellular lipolytic activity, growth at lower temperatures (less than 20 °C) and in high salt concentrations (10% NaCl). Molecular identification using ITS and D1/D2 sequences suggested NCIM 3590 to be 100% identical with reference strain Yarrowia bubula CBS 12934 rather than Y. lipolytica CBS 6124 (87% identity) while phylogenetic analysis revealed that it clustered with Y. bubula under a separate clade. Further, whole genome sequencing of NCIM 3590 was performed using Illumina NextSeq technology and the draft reported here. The overall genome relatedness values obtained by dDDH (94.1%), ANI...

AIP Advances, 2021

Two-dimensional materials and their assemblies have attracted considerable attention due to their... more Two-dimensional materials and their assemblies have attracted considerable attention due to their versatile properties for various applications. Among them, recently proposed octagonal monolayers (o-MLs) of C and BN are investigated for thermal, dynamical, and energetic stability. These robust o-MLs are then probed for patterned hybrid assemblies due to inherent low lattice mismatch and metallic and wide bandgap insulator combination to study their electronic structure for applications. Carbon substitution in boron nitride in the form of eight membered rings is found to be stable, and the variation of the substituted rings in the patterned hybrid o-MLs changes the structure from an insulating phase to a metallic phase. Such predicted structures may provide impetus for their practical realization.

Cilliopathies are the newer group of human genetic disorders in which the cilliary structure or f... more Cilliopathies are the newer group of human genetic disorders in which the cilliary structure or function is affected. Hepatorenal fi brocystic diseases (HRFCDs) are a part of cilliopathies and characterized by developmental abnormalities of the portobiliary system along with fi brocystic change in the kidneys. Polycystic kidney diseases (PKD) which is the largest subclass of HRFCDs had autosomal dominant and recessive forms. Autosomal dominant PKD (ADPKD) is characterized by multiple, bilateral renal cysts along with extra-renal manifestations. Liver is the most common extra-renal organ affected in ADPKD. Congenital hepatic fi brosis (CHF), is a rare, but well known forms of liver involvement in ADPKD. We report a case of a 26-year-old male was admitted to Lokmanya Tilak Municipal Hospital for the sudden loss of consciousness and one episode of convulsion in July 2012. Patient succumbed to his illness within 2 h, autopsy revealed bilaterally enlarged polycystic kidneys. Liver showed...

International Journal of Advance Research and Innovative Ideas in Education, 2018

Data mining methods has its broad research in the field of education. The overall goal of data mi... more Data mining methods has its broad research in the field of education. The overall goal of data mining is to extract data from a dataset and transform it into useful structure for further use. the Placement of students is one of the very important Role in educational institutions. We propose a TPO management system to predict eligible candidate for campus drive. The objective is to analyze previous year's student's historical data and predict placement eligibility of the current students and the percentage placement chance of the institution. We used Decision tree C4.5 Algorithm. Decision tree C4.5 algorithms are applied on Company’s previous year data & current requirement to generate the model and this model can be useful to predict the students’ eligibility in various companies. according to company eligibility criteria we will send the notification to those candidate who are eligible for that campus drive. here we check the eligibility of candidate on basis of percentage ...

La presente invention concerne des compositions topiques stables comprenant du luliconazole. En o... more La presente invention concerne des compositions topiques stables comprenant du luliconazole. En outre, la presente invention concerne egalement des compositions topiques stables comprenant une combinaison de luliconazole avec un corticoide tel que la betamethasone ou le clobetasol. Les compositions sont exemptes d'alcool aliphatique et de cetone.

Bulletin of the American Physical Society, 2017

Journal of Research in Engineering and Applied Sciences, 2018

In the present manuscript we report the structural and optical properties of terbium doped lantha... more In the present manuscript we report the structural and optical properties of terbium doped lanthanum orthophosphate nanophosphor capped with assorted capping agents and synthesized by conventional sol-gel method. The fabricated nanophosphor has been characterized using XRD (X-ray diffraction), SEM (Scanning electron microscopy), TG /DTA (thermo gravimetric analysis), PL (Photoluminescence spectroscopy) and FTIR (Fourier transform infra red spectroscopy). The studies explored that host LaPO4 when annealed at higher temperatures of 1000°C exhibit monazite structure which remain unaltered even after the addition of distinct capping agents like polyethylene glycol (PEG), Pyridine (PY) and Polystyrene (PS). The optical emission spectrum has been characterized with a broad band centered at 492nm and another spectral band at 545nm respectively. PL studies reveal that different spectral emission transitions are a consequence of typical 4f-4f intra configurational forbidden transitions of Tb3+. Additions of suitable capping agents have shown improvement in luminescence efficiency due to surface defect passivation. The present work confirms lanthanum orthophosphate nano phosphor doped with Tb3+ as a suitable host for phosphor converted LEDs and solid state lighting.

ACS Omega, 2018

Electronic structure of nearly stoichiometric and nonstoichiometric clusters of ZnO having bulk-l... more Electronic structure of nearly stoichiometric and nonstoichiometric clusters of ZnO having bulk-like wurtzite geometry passivated with fictitious hydrogen atoms are comparatively analyzed for structural evolution using density functional theory-based electronic structure calculations. A parameter, average binding energy per atomic number (ABE-number), is introduced for better insight of structural evolution. The stability of a cluster is determined by binding energy per atom and ABE-number, whereas structural evolution on the basis of spin-polarized energy spectrum is studied via site projected partial density of states (l-DOS). The overall structural evolution is mapped for bare and passivated ZnO clusters to l-DOS. The study has established a correlation between the stability of clusters and their l-DOS. O-excess and O-surfaced clusters are found to be more stable. The HOMO−LUMO gap varies from 0 to 6.3 eV by tuning the size, composition, and surface termination of the clusters. Present results reported for clusters of sizes up to ∼1 nm can pave a path for formulating strategies for experimental synthesis of ZnO nanoparticles for tuning the HOMO−LUMO gap.

Journal of the Endocrine Society

Background Pseudohypoparathyroidism (PHP) is a heterogeneous group of disorders in which resistan... more Background Pseudohypoparathyroidism (PHP) is a heterogeneous group of disorders in which resistance to parathyroid hormone (PTH) in the proximal renal tubules leads to hypocalcemia, hyperphosphatemia, and impaired 1,25(OH)2 vitamin D production. Clinical Case A 2-month-old child presented with history of recurrent focal seizures since last 10 days. During the first episode, the child was treated with anti- convulsant by paediatrician. Five days later she again developed focal seizures, this time the child was evaluated and serum calcium was 5.6 mg/dl (normal, 8.6-10.2 mg/dl), phosphorus 7.5 mg/dL (normal, 4. 0-7. 0 mg/dL), and magnesium 2. 0 mg/dL (normal 1.8-2.4 mg/dL). In view of symptomatic hypocalcemia, she was treated with I. V. 10% calcium gluconate and oral calcifediol (800 IU/day). The child was seizure free but still had hypocalcemia - serum calcium-6.8 mg/dl, hence the child was evaluated further- serum PTH was 561 pg/mL (normal, 9-91 pg/mL), 25-hydroxyvitamin D was 54.1 n...

Journal of the Endocrine Society

Introduction Rathke's cleft cysts (RCC) are cystic sellar and suprasellar lesion derived from... more Introduction Rathke's cleft cysts (RCC) are cystic sellar and suprasellar lesion derived from remnant of Rathke's pouch. RCC are mainly asymptomatic, but can present with headache, visual disturbance, panhypopituitarism, hypothalamic dysfunction when it enlarges causing compression to the surrounding structure. Diabetes insipidus as a presenting feature of RCC is rare. Even it presents with diabetes insipidus, it occurs more in elderly. Clinical Case A 32-year-old married female, mother of one child, having normal menstrual cycle presented with polyuria, polydipsia of recent onset. Clinical examinations was normal. Serum creatinine, potassium, calcium, plasma glucose were within normal range. Anterior pituitary hormonal evaluation was normal. Serum sodium was in the upper range of normal. Basal urine osmolality and serum osmolality were 87.49 mosm/kg (150 -1150 mOsm/kg) and 287 mOsm/kg (275 -295 mOsm/kg) respectively. Water deprivation test followed by vasopressin challenge ...

Cureus

Graves' dermopathy is one of the extra-thyroidal manifestations of Graves' disease (GD) and is ch... more Graves' dermopathy is one of the extra-thyroidal manifestations of Graves' disease (GD) and is characterized by the accumulation of glycosaminoglycans in the reticular dermis. In the majority of cases, pretibial myxedema is self-limiting but, in some cases, it can lead to structural and functional damage. Topical steroids with occlusive dressing remain the conventional treatment, but intralesional steroids have shown promising results. We hereby present a case of pretibial myxedema treated successfully with intralesional triamcinolone acetate.

14th International Conference on Automotive User Interfaces and Interactive Vehicular Applications

Diabetes

Aims: To study the effect of Vitamin D replacement on glycaemic control and pregnancy outcomes in... more Aims: To study the effect of Vitamin D replacement on glycaemic control and pregnancy outcomes in Gestational Diabetes Mellitus patient with Vitamin D deficiency. Methods: In this prospective, open-label interventional study 60 GDM subjects with Vitamin D deficiency were divided into 2 groups of 30 each, and the intervention group received 60,000 IU of cholecalciferol weekly for 6 weeks and then monthly for the duration of pregnancy. while the control group did not. Vitamin D status was re-assessed at 32 weeks of gestation for both groups. The glycaemic status was assessed using fasting plasma glucose and 1-hour and 2-hour postprandial glucose at 30 weeks of gestation and at time of delivery. Feto-maternal outcomes: Time of delivery (weeks of gestation) , method of delivery, pre-eclampsia, still-birth, neonatal hypoglycaemia, neonatal jaundice, birth weight, head circumference of the baby, APGAR score at 5 minutes in both groups were also assessed. Results: In the intervention group...

Vasantrao Naik Marathwada Krishi Vidyapeeth, Parbhani, Aug 28, 2017

Journal of Physical Chemistry C, Jan 10, 2019

Strong, directional, N bonding led surface stabilization is induced to obtain free-standing two-d... more Strong, directional, N bonding led surface stabilization is induced to obtain free-standing two-dimensional (2D) layered assemblies of Lonsdaleite and diamond-phase carbon by surface termination at three coordinated C sites. These assemblies have strong bonding and surface N lone pair induced self-protection and achieve respective bulk-like electronic, mechanical, and crystallographic properties at as low as seven atomic layer thickness. Lonsdaleite phase subnano thickness free-standing as small as three layered assembly shows bulk-like thermal stability up to 2900 K. Size confinement effect dominates up to four layered assembly, and then electronic and crystallographic properties are dominated by bulk stabilization which saturates toward respective bulk-like features from seven layered assembly. Similarly, free-standing hybrid assemblies of Lonsdaleite phase carbon with BeF (C5NBeF) and BS (C5NBS) layer are also proposed along with low symmetric Cm-C3N4 layered assembly. The combination of N and O is sho...

Cureus, 2022

Juvenile granulosa cell tumor leading to isosexual peripheral precocious puberty is a well-known ... more Juvenile granulosa cell tumor leading to isosexual peripheral precocious puberty is a well-known association. Here, we report a rare case of central precocious puberty secondary to granulosa cell tumor of the ovary. A five-year and five-month-old girl presented with a history of progressive enlargement of bilateral breasts and intermittent vaginal spotting, associated with growth acceleration. Elevated estradiol and suppressed serum follicle-stimulating hormone were found on investigation. Additionally, abdominal and pelvic ultrasonography was suggestive of a right ovarian mass, which proved to be a juvenile granulosa cell tumor on histopathology and immunohistochemistry, leading to a diagnosis of peripheral precocious puberty secondary to granulosa cell tumor of the ovary. One and a half years after resection of the tumor, secondary sexual characteristics progressed with regression of tumor markers, and no mass was noted on ultrasonography, leading to the suspicion of central precocious puberty. Pubertal basal luteinizing hormone (LH) and elevated triptorelin-stimulated LH confirmed the diagnosis of central precocious puberty secondary to granulosa cell tumor of the ovary.

Investigation for M-40 grade of concrete having mix proportion 1:1.27:2.52 with water cement rati... more Investigation for M-40 grade of concrete having mix proportion 1:1.27:2.52 with water cement ratio 0.4 to study the compressive strength, flexural strength of steel fibre reinforced concrete (SFRC) containing fibers of 1% volume fraction of dramix fiber. A result data obtained has been analyzed and compared with a control specimen (0% fiber). Result data clearly shows percentage increase in 28 days Compressive strength, Flexural strength for M-40 Grade of Concrete.

An entry from the Inorganic Crystal Structure Database, the world's repository for inorganic ... more An entry from the Inorganic Crystal Structure Database, the world's repository for inorganic crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the joint CCDC and FIZ Karlsruhe Access Structures service and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.

Annals of Pathology and Laboratory Medicine, 2016

Background: The primary pediatric brain tumors (PBT) are the second most common cause of death du... more Background: The primary pediatric brain tumors (PBT) are the second most common cause of death due to malignancies in children. This study was done to analyze the histological spectrum of primary brain tumors in children and also to find out the epidemiology of the common pediatric brain tumors. Methods: Data regarding age, gender, topography, and histopathology of 239 pediatric patients (0–18 years) with brain tumors operated over a period of 15 years (January-2001 to December-2015) was collected and analyzed according to World Health Organization 2007 classification Result: PBTs were more common in males (54.8%) as compared to females (45.2%) with male to female ratio of 1.21:1. Frequency of tumors was higher in childhood age group (>5-<15 years) i.e. (55.6%) when compared to adolescent age group (15.9%). The most common anatomical site was cerebellum (40.5%), followed by hemispheres (21.4%). Supratentorial tumors (51.9%) were predominant than infratentorial tumors (45.2%) a...

arXiv: Materials Science, 2020

A new class of tetragonally symmetric 2D octagonal family of monolayers (o-MLs) has emerged recen... more A new class of tetragonally symmetric 2D octagonal family of monolayers (o-MLs) has emerged recently and demands understanding at the fundamental level. o-MLs of metal nitride and carbide family (BN, AlN, GaN, GeC, SiC) along with C and BP are computationally designed and their stability and electronic structure are investigated. These binary o-MLs show mixed ionic and covalent bonding with the hybridized p states dominating the electronic structure around the Fermi level. Geometric and structural similarity of o-C and o-BN has been exploited to form patterned hybrid o-MLs ranging from metallic to insulating phases. Stacking of zigzag buckled o-MLs results in stable body centered tetragonal (bct)-bulk phase that is suitable for most materials from group IV, III-V and II-VI. Vertically cut chunks of o-BN and o-C bulk or stacking of o-rings, unlike rolling of hexagonal (h)-ML, provide a plausible way to form very thin o-nanotubes (o-NT). Confined and bulk structures formed with an oct...

Scientific Reports, 2021

Yarrowia clade contains yeast species morphologically, ecologically, physiologically and genetica... more Yarrowia clade contains yeast species morphologically, ecologically, physiologically and genetically diverse in nature. Yarrowia lipolytica NCIM 3590 (NCIM 3590), a biotechnologically important strain, isolated from Scottish sea waters was reinvestigated for its phenotypic, biochemical, molecular and genomic properties as it exhibited characteristics unlike Y. lipolytica, namely, absence of extracellular lipolytic activity, growth at lower temperatures (less than 20 °C) and in high salt concentrations (10% NaCl). Molecular identification using ITS and D1/D2 sequences suggested NCIM 3590 to be 100% identical with reference strain Yarrowia bubula CBS 12934 rather than Y. lipolytica CBS 6124 (87% identity) while phylogenetic analysis revealed that it clustered with Y. bubula under a separate clade. Further, whole genome sequencing of NCIM 3590 was performed using Illumina NextSeq technology and the draft reported here. The overall genome relatedness values obtained by dDDH (94.1%), ANI...

AIP Advances, 2021

Two-dimensional materials and their assemblies have attracted considerable attention due to their... more Two-dimensional materials and their assemblies have attracted considerable attention due to their versatile properties for various applications. Among them, recently proposed octagonal monolayers (o-MLs) of C and BN are investigated for thermal, dynamical, and energetic stability. These robust o-MLs are then probed for patterned hybrid assemblies due to inherent low lattice mismatch and metallic and wide bandgap insulator combination to study their electronic structure for applications. Carbon substitution in boron nitride in the form of eight membered rings is found to be stable, and the variation of the substituted rings in the patterned hybrid o-MLs changes the structure from an insulating phase to a metallic phase. Such predicted structures may provide impetus for their practical realization.

Cilliopathies are the newer group of human genetic disorders in which the cilliary structure or f... more Cilliopathies are the newer group of human genetic disorders in which the cilliary structure or function is affected. Hepatorenal fi brocystic diseases (HRFCDs) are a part of cilliopathies and characterized by developmental abnormalities of the portobiliary system along with fi brocystic change in the kidneys. Polycystic kidney diseases (PKD) which is the largest subclass of HRFCDs had autosomal dominant and recessive forms. Autosomal dominant PKD (ADPKD) is characterized by multiple, bilateral renal cysts along with extra-renal manifestations. Liver is the most common extra-renal organ affected in ADPKD. Congenital hepatic fi brosis (CHF), is a rare, but well known forms of liver involvement in ADPKD. We report a case of a 26-year-old male was admitted to Lokmanya Tilak Municipal Hospital for the sudden loss of consciousness and one episode of convulsion in July 2012. Patient succumbed to his illness within 2 h, autopsy revealed bilaterally enlarged polycystic kidneys. Liver showed...

International Journal of Advance Research and Innovative Ideas in Education, 2018

Data mining methods has its broad research in the field of education. The overall goal of data mi... more Data mining methods has its broad research in the field of education. The overall goal of data mining is to extract data from a dataset and transform it into useful structure for further use. the Placement of students is one of the very important Role in educational institutions. We propose a TPO management system to predict eligible candidate for campus drive. The objective is to analyze previous year's student's historical data and predict placement eligibility of the current students and the percentage placement chance of the institution. We used Decision tree C4.5 Algorithm. Decision tree C4.5 algorithms are applied on Company’s previous year data & current requirement to generate the model and this model can be useful to predict the students’ eligibility in various companies. according to company eligibility criteria we will send the notification to those candidate who are eligible for that campus drive. here we check the eligibility of candidate on basis of percentage ...

La presente invention concerne des compositions topiques stables comprenant du luliconazole. En o... more La presente invention concerne des compositions topiques stables comprenant du luliconazole. En outre, la presente invention concerne egalement des compositions topiques stables comprenant une combinaison de luliconazole avec un corticoide tel que la betamethasone ou le clobetasol. Les compositions sont exemptes d'alcool aliphatique et de cetone.

Bulletin of the American Physical Society, 2017

Journal of Research in Engineering and Applied Sciences, 2018

In the present manuscript we report the structural and optical properties of terbium doped lantha... more In the present manuscript we report the structural and optical properties of terbium doped lanthanum orthophosphate nanophosphor capped with assorted capping agents and synthesized by conventional sol-gel method. The fabricated nanophosphor has been characterized using XRD (X-ray diffraction), SEM (Scanning electron microscopy), TG /DTA (thermo gravimetric analysis), PL (Photoluminescence spectroscopy) and FTIR (Fourier transform infra red spectroscopy). The studies explored that host LaPO4 when annealed at higher temperatures of 1000°C exhibit monazite structure which remain unaltered even after the addition of distinct capping agents like polyethylene glycol (PEG), Pyridine (PY) and Polystyrene (PS). The optical emission spectrum has been characterized with a broad band centered at 492nm and another spectral band at 545nm respectively. PL studies reveal that different spectral emission transitions are a consequence of typical 4f-4f intra configurational forbidden transitions of Tb3+. Additions of suitable capping agents have shown improvement in luminescence efficiency due to surface defect passivation. The present work confirms lanthanum orthophosphate nano phosphor doped with Tb3+ as a suitable host for phosphor converted LEDs and solid state lighting.

ACS Omega, 2018

Electronic structure of nearly stoichiometric and nonstoichiometric clusters of ZnO having bulk-l... more Electronic structure of nearly stoichiometric and nonstoichiometric clusters of ZnO having bulk-like wurtzite geometry passivated with fictitious hydrogen atoms are comparatively analyzed for structural evolution using density functional theory-based electronic structure calculations. A parameter, average binding energy per atomic number (ABE-number), is introduced for better insight of structural evolution. The stability of a cluster is determined by binding energy per atom and ABE-number, whereas structural evolution on the basis of spin-polarized energy spectrum is studied via site projected partial density of states (l-DOS). The overall structural evolution is mapped for bare and passivated ZnO clusters to l-DOS. The study has established a correlation between the stability of clusters and their l-DOS. O-excess and O-surfaced clusters are found to be more stable. The HOMO−LUMO gap varies from 0 to 6.3 eV by tuning the size, composition, and surface termination of the clusters. Present results reported for clusters of sizes up to ∼1 nm can pave a path for formulating strategies for experimental synthesis of ZnO nanoparticles for tuning the HOMO−LUMO gap.