Preeti Tomar Bhattacharya - Academia.edu (original) (raw)

Papers by Preeti Tomar Bhattacharya

Research paper thumbnail of Probiotics and Prebiotics: Role as Functional Foods in General and Oral Health

Each day, every human being ingests a large number of living microorganisms, predominantly bacter... more Each day, every human being ingests a large number of living microorganisms, predominantly bacteria. Although these organisms are naturally present in food and water, they can also be deliberately added during the processing of foods such as sausages, cheese, yogurt and fermented milk products. For several decades now, bacteria called probiotics have been added to some foods because of their beneficial effects for human health. Although only a few clinical studies have been conducted so far, the results to date suggest that probiotics could be useful in preventing and treating oral infections, including dental caries, periodontal disease and halitosis. This article summarizes the currently available data on the potential benefits of probiotics for general and oral health.

Research paper thumbnail of We report a case of pleomorphic adenoma in the upper lip of an elderly female with emphasis on differential diagnosis and relevant review of literature

Pleomorphic adenoma is the most common tumor of the salivary glands. About 90% of these tumors oc... more Pleomorphic adenoma is the most common tumor of the salivary glands. About 90% of these tumors occur in the parotid gland and 10% in the minor salivary glands. The most common site for pleomorphic adenoma of the minor salivary glands is the palate followed by upper lip. Surgical removal with adequate margins is the principal treatment. Due to its microscopic projections, this tumor requires a wide resection to avoid recurrence. We report a case of pleomorphic adenoma in the upper lip of an elderly female with emphasis on differential diagnosis and relevant review of literature.

Research paper thumbnail of Effects of Iron Deficiency on the Oropharyngeal Region: Signs, Symptoms, and Biological Changes

Handbook of Famine, Starvation, and Nutrient Deprivation, 2017

Iron is the most abundant essential trace element inside human body. Iron deficiency anemia is th... more Iron is the most abundant essential trace element inside human body. Iron deficiency anemia is the most common nutritional deficiency worldwide. It reportedly causes reduction in working capacity, hampers mental development in growing children and young adults, and significantly worsens the quality of daily life. Nonpregnant women in reproductive age group and pregnant women are equally vulnerable to iron deficiency. Apart from systemic signs and symptoms like pallor, fatigability, palpitations, koilonychia, light headedness, and shortness of breath, oropharyngeal region can also provide important diagnostic clues to this systemic condition. Moreover, other oral conditions such as aphthous ulcers and burning mouth syndrome; premalignant conditions such as Plummer Vinson syndrome, oral lichen planus, and oral submucous fibrosis; and malignant disease such as oral squamous carcinoma have been associated with iron deficient state. This review appraises various signs and symptoms encountered within oropha-ryngeal region in the iron deficient state and underlying biological changes responsible for those clinical manifestations.

Research paper thumbnail of Odontogenic myxoma involving maxilla: A case report

Odontogenic myxoma is a rare benign odontogenic tumor of the oral cavity which is locally aggress... more Odontogenic myxoma is a rare benign odontogenic tumor of the oral cavity which is locally aggressive and non metastasizing. The mandible is more commonly involved than maxilla. It usually presents as a painless swelling in second to third decade of life. Radiographically, it can be unilocular or multilocular, so the diagnosis is not easy many times. It poses a diagnostic and therapeutic challenge because of its morphology and biologic behavior. We represent a case of 35-year-old female who had an asymptomatic swelling in maxillary right region since 7 months.

Research paper thumbnail of A Radiographic Study on the Visualization of the Anterior Loop in Darbhanga Population - An Original Research

International Journal of Contemporary Medical Research [IJCMR], May 1, 2019

Research paper thumbnail of A Radiographic Study to Evaluate the Course and Visibility of the Mandibular Canal in Darbhanga Population: An Original Research

International Journal of Contemporary Medical Research [IJCMR], May 1, 2019

Research paper thumbnail of Oro-dental considerations in transplant recipients

International Dental & Medical Journal of Advanced Research - VOLUME 2015, 2015

Research paper thumbnail of Dual cusped protostylid: Case report and clinical significance

Journal of Indian Academy of Oral Medicine and Radiology, 2016

Protostylids are superstructures on maxillary or mandibular molars, which have rarely been report... more Protostylids are superstructures on maxillary or mandibular molars, which have rarely been reported in literature, and the significance of their presence has also been underestimated. The dental practitioners may easily misdiagnose a tooth, with such conical tubercles as malformed tooth. Interestingly, this is neither a malformation nor an anomaly but rather an important morphological trait of an individual. Once in a while, one may come across such a distinct morphological trait without being able to diagnose. To the authors' best knowledge, only one similar case has been reported previously, and the second such case internationally. Bearing all such facts in mind, the authors attempt to educate the readers towards the existence of such a trait so that it can be identified and studied in larger numbers. Hence, it is the authors' endeavor to report an unusual case of dual cusped maxillary protostylid along with its clinical significance.

Research paper thumbnail of Radiation protection in dentistry - Do we practice what we learn?

Journal of Advanced Clinical & Research Insights, 2015

Research paper thumbnail of Nutritional Aspects of Essential Trace Elements in Oral Health and Disease: An Extensive Review

Scientifica, 2016

Human body requires certain essential elements in small quantities and their absence or excess ma... more Human body requires certain essential elements in small quantities and their absence or excess may result in severe malfunctioning of the body and even death in extreme cases because these essential trace elements directly influence the metabolic and physiologic processes of the organism. Rapid urbanization and economic development have resulted in drastic changes in diets with developing preference towards refined diet and nutritionally deprived junk food. Poor nutrition can lead to reduced immunity, augmented vulnerability to various oral and systemic diseases, impaired physical and mental growth, and reduced efficiency. Diet and nutrition affect oral health in a variety of ways with influence on craniofacial development and growth and maintenance of dental and oral soft tissues. Oral potentially malignant disorders (OPMD) are treated with antioxidants containing essential trace elements like selenium but even increased dietary intake of trace elements like copper could lead to or...

Research paper thumbnail of Prevalence and subjective knowledge of tongue lesions in an Indian population

Journal of Oral Biology and Craniofacial Research, 2016

Aim: The current study was designed to determine prevalence of various tongue lesions and their a... more Aim: The current study was designed to determine prevalence of various tongue lesions and their association with age, gender, systemic illness, deleterious habits, and distribution over the surfaces of tongue. It also explored the awareness and knowledge of subjects in relation to presence of tongue lesions, etiological factor, symptoms, and treatment received if any. Methods: The present study was conducted on 1360 randomly selected dental outpatients from 1/10/2013 to 30/09/2014. Examination of tongue included surface changes, size, movements, and the presence of mucosal lesions. The subjects were asked about the knowledge, symptoms, and treatment obtained in case of awareness regarding the lesion. Results: The prevalence of tongue lesions was found to be 13.75%. The most prevalent lesion was found to be coated tongue. The majority of the lesions were located on dorsum of tongue and not related with age, gender, habit, and systemic condition. A considerable number of subjects were aware of the changes on their tongue but negligible number sought any treatment. Conclusions: The presence of tongue lesions in the study population was found be significant. Hence, general dental practitioners and health care providers should be educated about the diagnosis, etiology, investigations, and proper management of such tongue lesions.

Research paper thumbnail of Erupted complex composite odontoma: Report of two atypical cases

Journal of Dental and Allied Sciences, 2015

Odontomas are nonaggressive, hamartomatous developmental malformations of odontogenic origin. The... more Odontomas are nonaggressive, hamartomatous developmental malformations of odontogenic origin. They are considered one of the most common odontogenic lesions composed by diverse dental tissues. They may interfere with the eruption of an associated tooth and are more prevalent in the posterior mandible. The eruption of a complex odontoma into the oral cavity is rare. Here, we report such two rare cases of gigantic erupted complex composite odontomas.

Research paper thumbnail of Oral submucous fibrosis secondary to iron deficiency anemia: A case report, etiopathogenesis and management

The journal of nutrition, health & aging, 2015

Research paper thumbnail of Diagnostic efficacy of saliva in oral and systemic health

international journal of stomatology & occlusion medicine, 2015

Saliva has the potential to become a first-line diagnostic sample of choice owing to the advancem... more Saliva has the potential to become a first-line diagnostic sample of choice owing to the advancements in detection technologies coupled with combinations of biomolecules with clinical relevance. Saliva is increasingly being used as an investigational aid in the diagnosis of oral and systemic diseases. It is a complex fluid containing a variety of enzymes, hormones, antibodies, antimicrobial constituents, and growth factors. Thus, saliva is functionally equivalent to serum, but its low concentration compared with serum levels in the blood may prevent salivary diagnostics from being clinically practical. However, with the development of new and highly sensitive techniques the low concentration of analytes in saliva is no longer a limitation. Evaluation of the secretions from individual salivary glands is useful for the detection of gland-specific pathology and whole saliva is used for the evaluation of systemic disorders. This review article highlights the diagnostic applications of saliva for systemic diseases and for monitoring of general health.

Research paper thumbnail of Maxillary sinus septa

international journal of stomatology & occlusion medicine, 2015

BackgroundThe present study sought to determine the prevalence and characteristics of maxillary s... more BackgroundThe present study sought to determine the prevalence and characteristics of maxillary sinus septa on panoramic radiographs since conventional imaging modalities are still extensively used in developing country like India. The study assessed the prevalence and characteristics of maxillary sinus septa in edentulous and dentate maxillary arches.Patients and methodsThe sample consisted of 445 outpatients visiting the department of Oral Medicine and Radiology. Standardized panoramic radiographs were made of all the study subjects and then interpreted for various parameters pertaining to the maxillary sinus septa.ResultsThe prevalence of maxillary sinus septa in Indian population was estimated to be 34%. Maxillary sinus septa prevalence in 800 maxillary sinuses (2 maxillary sinuses per subject in 400 subjects studied) was found to be 24.9%. There was no age, gender, or dental status predilection for the occurrence of maxillary sinus septa. A total of 255 maxillary sinus septa were detected in 136 subjects. Of the 255 maxillary sinus septa, 44.7 % were located in the anterior region, 44.7 % in the middle region, and 10.6 % in the posterior region.ConclusionA considerable number of maxillary sinus septa were seen in the Indian population of this study. There was no age or gender predilection for the occurrence of maxillary sinus septa. The majority of maxillary sinus septa were located in the anterior and middle regions of the maxillary sinus floor. The presence of maxillary sinus septa was unrelated to dental status.

Research paper thumbnail of Mast Cells in Oral Inflammatory Lesions- a Pilot Study

World Journal of Pharmaceutical Research

Background: Paul Ehrlich first described mast cells in 1878 based on their unique staining charac... more Background: Paul Ehrlich first described mast cells in 1878 based on their unique staining characteristics and large granules and are considered part of the immune system. When triggered by locally produced cytokines or bacterial products the cells can release a number of pre stored mediators. They are characterized by the presence of densely packed cytoplasm with bright red granules that stain metachromatically with Toluidine blue, Azure A, Bismarch brown and Thionin. Aim & Objective: The present study was conducted to determine the distribution of mast cells and correlate their presence with the state of vascularity and inflammation with the metachromatic dye- 1% Toluidine blue. Results: The distribution was predominantly mild in most of the cases (80.95% cases) and moderate / severe in19.05% cases. The distribution of vascularity was found to be mild in 12.6% cases, whereas in rest of the 87.30% cases, the vascularity was found to be increased. The concentration of inflammatory c...

Research paper thumbnail of Histopathological Analysis of Verrucous Carcinoma with Pas Stain Transforming Into Invasive Squamous Cell Carcinoma

Ackerman’s tumour commonly known as Verrucous carcinoma (VC) is a low grade variant of oral squam... more Ackerman’s tumour commonly known as Verrucous carcinoma (VC) is a low grade variant of oral squamous cell carcinoma (OSCC). The oral cavity and larynx have been reported to be the commonest sites of involvement in the head and neck regions. VC is characterised with presence of minimal degree of dysplasia and biological aggressiveness, the principal etiological factor being tobacco usage. Its distinctive histopathological features make it exigent for diagnosis and build a close association between the clinician and the histopathologist. Hereby we report a rare case of verrucous carcinoma on the right buccal mucosa of a 48 year old male patient progressing into invasive squamous cell carcinoma.

Research paper thumbnail of Cone Beam Computed Tomography: A New Era in Maxillofacial Imaging

Since decades, two dimensional (2D) imaging modalities such as cephalometrics, panoramic and peri... more Since decades, two dimensional (2D) imaging modalities such as cephalometrics, panoramic and periapical radiography have been the gold standard for diagnosing and treatment planning in dentistry. Nevertheless, this 2D representation has still left some queries unreciprocated which have set the goal towards three dimensional technologies. The advent of cone beam computed tomography is changing the vision of dentists towards the oral and maxillofacial complex. This article reviews this promising technology and its application in various fields of dentistry.

Research paper thumbnail of An Intricate Clinicopathologic Presentation of Calcifying Odontogenic Cyst

Calcifying odontogenic cyst (COC) is considered to be an uncommon benign entity which was first r... more Calcifying odontogenic cyst (COC) is considered to be an uncommon benign entity which was first recognized by Gorlin. Calcifying odontogenic cyst accounts for only 2% of all the odontogenic tumors and is a relatively rare lesion which is characterized by histological diversity as its clinical and radiological features are not pathognomonic. Here, we report a case of COC in a 45 years old male patient with a long standing swelling.

Research paper thumbnail of Principle and Techniques of Immunohistochemistry – a Review

Immunohistochemistry is a technique for identifying cellular or tissue constituents (antigens) by... more Immunohistochemistry is a technique for identifying cellular or tissue constituents (antigens) by means of antigen-antibody interactions, the site of antibody binding being identified by direct labelling of the antibody, or by use of secondary labelling method. Although histological analysis of Haematoxylin & Eosin stained tissue sections remains at the core of the practice of head and neck surgical pathology, immunohistochemistry has become a powerful tool in the armamentarium of the pathologist. The selection of antibodies for the immunohistochemical testing is made on the basis of their tumor specificity and the likelihood that they will react with the tumor under evaluation. IHC is a well-established ancillary technique to facilitate the diagnosis of infectious and neoplastic processes in animals. Immunohistochemical studies have traditionally focused on markers of specific cell and/or tumour type as aids in the diagnosis of specific tumours.

Research paper thumbnail of Probiotics and Prebiotics: Role as Functional Foods in General and Oral Health

Each day, every human being ingests a large number of living microorganisms, predominantly bacter... more Each day, every human being ingests a large number of living microorganisms, predominantly bacteria. Although these organisms are naturally present in food and water, they can also be deliberately added during the processing of foods such as sausages, cheese, yogurt and fermented milk products. For several decades now, bacteria called probiotics have been added to some foods because of their beneficial effects for human health. Although only a few clinical studies have been conducted so far, the results to date suggest that probiotics could be useful in preventing and treating oral infections, including dental caries, periodontal disease and halitosis. This article summarizes the currently available data on the potential benefits of probiotics for general and oral health.

Research paper thumbnail of We report a case of pleomorphic adenoma in the upper lip of an elderly female with emphasis on differential diagnosis and relevant review of literature

Pleomorphic adenoma is the most common tumor of the salivary glands. About 90% of these tumors oc... more Pleomorphic adenoma is the most common tumor of the salivary glands. About 90% of these tumors occur in the parotid gland and 10% in the minor salivary glands. The most common site for pleomorphic adenoma of the minor salivary glands is the palate followed by upper lip. Surgical removal with adequate margins is the principal treatment. Due to its microscopic projections, this tumor requires a wide resection to avoid recurrence. We report a case of pleomorphic adenoma in the upper lip of an elderly female with emphasis on differential diagnosis and relevant review of literature.

Research paper thumbnail of Effects of Iron Deficiency on the Oropharyngeal Region: Signs, Symptoms, and Biological Changes

Handbook of Famine, Starvation, and Nutrient Deprivation, 2017

Iron is the most abundant essential trace element inside human body. Iron deficiency anemia is th... more Iron is the most abundant essential trace element inside human body. Iron deficiency anemia is the most common nutritional deficiency worldwide. It reportedly causes reduction in working capacity, hampers mental development in growing children and young adults, and significantly worsens the quality of daily life. Nonpregnant women in reproductive age group and pregnant women are equally vulnerable to iron deficiency. Apart from systemic signs and symptoms like pallor, fatigability, palpitations, koilonychia, light headedness, and shortness of breath, oropharyngeal region can also provide important diagnostic clues to this systemic condition. Moreover, other oral conditions such as aphthous ulcers and burning mouth syndrome; premalignant conditions such as Plummer Vinson syndrome, oral lichen planus, and oral submucous fibrosis; and malignant disease such as oral squamous carcinoma have been associated with iron deficient state. This review appraises various signs and symptoms encountered within oropha-ryngeal region in the iron deficient state and underlying biological changes responsible for those clinical manifestations.

Research paper thumbnail of Odontogenic myxoma involving maxilla: A case report

Odontogenic myxoma is a rare benign odontogenic tumor of the oral cavity which is locally aggress... more Odontogenic myxoma is a rare benign odontogenic tumor of the oral cavity which is locally aggressive and non metastasizing. The mandible is more commonly involved than maxilla. It usually presents as a painless swelling in second to third decade of life. Radiographically, it can be unilocular or multilocular, so the diagnosis is not easy many times. It poses a diagnostic and therapeutic challenge because of its morphology and biologic behavior. We represent a case of 35-year-old female who had an asymptomatic swelling in maxillary right region since 7 months.

Research paper thumbnail of A Radiographic Study on the Visualization of the Anterior Loop in Darbhanga Population - An Original Research

International Journal of Contemporary Medical Research [IJCMR], May 1, 2019

Research paper thumbnail of A Radiographic Study to Evaluate the Course and Visibility of the Mandibular Canal in Darbhanga Population: An Original Research

International Journal of Contemporary Medical Research [IJCMR], May 1, 2019

Research paper thumbnail of Oro-dental considerations in transplant recipients

International Dental & Medical Journal of Advanced Research - VOLUME 2015, 2015

Research paper thumbnail of Dual cusped protostylid: Case report and clinical significance

Journal of Indian Academy of Oral Medicine and Radiology, 2016

Protostylids are superstructures on maxillary or mandibular molars, which have rarely been report... more Protostylids are superstructures on maxillary or mandibular molars, which have rarely been reported in literature, and the significance of their presence has also been underestimated. The dental practitioners may easily misdiagnose a tooth, with such conical tubercles as malformed tooth. Interestingly, this is neither a malformation nor an anomaly but rather an important morphological trait of an individual. Once in a while, one may come across such a distinct morphological trait without being able to diagnose. To the authors' best knowledge, only one similar case has been reported previously, and the second such case internationally. Bearing all such facts in mind, the authors attempt to educate the readers towards the existence of such a trait so that it can be identified and studied in larger numbers. Hence, it is the authors' endeavor to report an unusual case of dual cusped maxillary protostylid along with its clinical significance.

Research paper thumbnail of Radiation protection in dentistry - Do we practice what we learn?

Journal of Advanced Clinical & Research Insights, 2015

Research paper thumbnail of Nutritional Aspects of Essential Trace Elements in Oral Health and Disease: An Extensive Review

Scientifica, 2016

Human body requires certain essential elements in small quantities and their absence or excess ma... more Human body requires certain essential elements in small quantities and their absence or excess may result in severe malfunctioning of the body and even death in extreme cases because these essential trace elements directly influence the metabolic and physiologic processes of the organism. Rapid urbanization and economic development have resulted in drastic changes in diets with developing preference towards refined diet and nutritionally deprived junk food. Poor nutrition can lead to reduced immunity, augmented vulnerability to various oral and systemic diseases, impaired physical and mental growth, and reduced efficiency. Diet and nutrition affect oral health in a variety of ways with influence on craniofacial development and growth and maintenance of dental and oral soft tissues. Oral potentially malignant disorders (OPMD) are treated with antioxidants containing essential trace elements like selenium but even increased dietary intake of trace elements like copper could lead to or...

Research paper thumbnail of Prevalence and subjective knowledge of tongue lesions in an Indian population

Journal of Oral Biology and Craniofacial Research, 2016

Aim: The current study was designed to determine prevalence of various tongue lesions and their a... more Aim: The current study was designed to determine prevalence of various tongue lesions and their association with age, gender, systemic illness, deleterious habits, and distribution over the surfaces of tongue. It also explored the awareness and knowledge of subjects in relation to presence of tongue lesions, etiological factor, symptoms, and treatment received if any. Methods: The present study was conducted on 1360 randomly selected dental outpatients from 1/10/2013 to 30/09/2014. Examination of tongue included surface changes, size, movements, and the presence of mucosal lesions. The subjects were asked about the knowledge, symptoms, and treatment obtained in case of awareness regarding the lesion. Results: The prevalence of tongue lesions was found to be 13.75%. The most prevalent lesion was found to be coated tongue. The majority of the lesions were located on dorsum of tongue and not related with age, gender, habit, and systemic condition. A considerable number of subjects were aware of the changes on their tongue but negligible number sought any treatment. Conclusions: The presence of tongue lesions in the study population was found be significant. Hence, general dental practitioners and health care providers should be educated about the diagnosis, etiology, investigations, and proper management of such tongue lesions.

Research paper thumbnail of Erupted complex composite odontoma: Report of two atypical cases

Journal of Dental and Allied Sciences, 2015

Odontomas are nonaggressive, hamartomatous developmental malformations of odontogenic origin. The... more Odontomas are nonaggressive, hamartomatous developmental malformations of odontogenic origin. They are considered one of the most common odontogenic lesions composed by diverse dental tissues. They may interfere with the eruption of an associated tooth and are more prevalent in the posterior mandible. The eruption of a complex odontoma into the oral cavity is rare. Here, we report such two rare cases of gigantic erupted complex composite odontomas.

Research paper thumbnail of Oral submucous fibrosis secondary to iron deficiency anemia: A case report, etiopathogenesis and management

The journal of nutrition, health & aging, 2015

Research paper thumbnail of Diagnostic efficacy of saliva in oral and systemic health

international journal of stomatology & occlusion medicine, 2015

Saliva has the potential to become a first-line diagnostic sample of choice owing to the advancem... more Saliva has the potential to become a first-line diagnostic sample of choice owing to the advancements in detection technologies coupled with combinations of biomolecules with clinical relevance. Saliva is increasingly being used as an investigational aid in the diagnosis of oral and systemic diseases. It is a complex fluid containing a variety of enzymes, hormones, antibodies, antimicrobial constituents, and growth factors. Thus, saliva is functionally equivalent to serum, but its low concentration compared with serum levels in the blood may prevent salivary diagnostics from being clinically practical. However, with the development of new and highly sensitive techniques the low concentration of analytes in saliva is no longer a limitation. Evaluation of the secretions from individual salivary glands is useful for the detection of gland-specific pathology and whole saliva is used for the evaluation of systemic disorders. This review article highlights the diagnostic applications of saliva for systemic diseases and for monitoring of general health.

Research paper thumbnail of Maxillary sinus septa

international journal of stomatology & occlusion medicine, 2015

BackgroundThe present study sought to determine the prevalence and characteristics of maxillary s... more BackgroundThe present study sought to determine the prevalence and characteristics of maxillary sinus septa on panoramic radiographs since conventional imaging modalities are still extensively used in developing country like India. The study assessed the prevalence and characteristics of maxillary sinus septa in edentulous and dentate maxillary arches.Patients and methodsThe sample consisted of 445 outpatients visiting the department of Oral Medicine and Radiology. Standardized panoramic radiographs were made of all the study subjects and then interpreted for various parameters pertaining to the maxillary sinus septa.ResultsThe prevalence of maxillary sinus septa in Indian population was estimated to be 34%. Maxillary sinus septa prevalence in 800 maxillary sinuses (2 maxillary sinuses per subject in 400 subjects studied) was found to be 24.9%. There was no age, gender, or dental status predilection for the occurrence of maxillary sinus septa. A total of 255 maxillary sinus septa were detected in 136 subjects. Of the 255 maxillary sinus septa, 44.7 % were located in the anterior region, 44.7 % in the middle region, and 10.6 % in the posterior region.ConclusionA considerable number of maxillary sinus septa were seen in the Indian population of this study. There was no age or gender predilection for the occurrence of maxillary sinus septa. The majority of maxillary sinus septa were located in the anterior and middle regions of the maxillary sinus floor. The presence of maxillary sinus septa was unrelated to dental status.

Research paper thumbnail of Mast Cells in Oral Inflammatory Lesions- a Pilot Study

World Journal of Pharmaceutical Research

Background: Paul Ehrlich first described mast cells in 1878 based on their unique staining charac... more Background: Paul Ehrlich first described mast cells in 1878 based on their unique staining characteristics and large granules and are considered part of the immune system. When triggered by locally produced cytokines or bacterial products the cells can release a number of pre stored mediators. They are characterized by the presence of densely packed cytoplasm with bright red granules that stain metachromatically with Toluidine blue, Azure A, Bismarch brown and Thionin. Aim & Objective: The present study was conducted to determine the distribution of mast cells and correlate their presence with the state of vascularity and inflammation with the metachromatic dye- 1% Toluidine blue. Results: The distribution was predominantly mild in most of the cases (80.95% cases) and moderate / severe in19.05% cases. The distribution of vascularity was found to be mild in 12.6% cases, whereas in rest of the 87.30% cases, the vascularity was found to be increased. The concentration of inflammatory c...

Research paper thumbnail of Histopathological Analysis of Verrucous Carcinoma with Pas Stain Transforming Into Invasive Squamous Cell Carcinoma

Ackerman’s tumour commonly known as Verrucous carcinoma (VC) is a low grade variant of oral squam... more Ackerman’s tumour commonly known as Verrucous carcinoma (VC) is a low grade variant of oral squamous cell carcinoma (OSCC). The oral cavity and larynx have been reported to be the commonest sites of involvement in the head and neck regions. VC is characterised with presence of minimal degree of dysplasia and biological aggressiveness, the principal etiological factor being tobacco usage. Its distinctive histopathological features make it exigent for diagnosis and build a close association between the clinician and the histopathologist. Hereby we report a rare case of verrucous carcinoma on the right buccal mucosa of a 48 year old male patient progressing into invasive squamous cell carcinoma.

Research paper thumbnail of Cone Beam Computed Tomography: A New Era in Maxillofacial Imaging

Since decades, two dimensional (2D) imaging modalities such as cephalometrics, panoramic and peri... more Since decades, two dimensional (2D) imaging modalities such as cephalometrics, panoramic and periapical radiography have been the gold standard for diagnosing and treatment planning in dentistry. Nevertheless, this 2D representation has still left some queries unreciprocated which have set the goal towards three dimensional technologies. The advent of cone beam computed tomography is changing the vision of dentists towards the oral and maxillofacial complex. This article reviews this promising technology and its application in various fields of dentistry.

Research paper thumbnail of An Intricate Clinicopathologic Presentation of Calcifying Odontogenic Cyst

Calcifying odontogenic cyst (COC) is considered to be an uncommon benign entity which was first r... more Calcifying odontogenic cyst (COC) is considered to be an uncommon benign entity which was first recognized by Gorlin. Calcifying odontogenic cyst accounts for only 2% of all the odontogenic tumors and is a relatively rare lesion which is characterized by histological diversity as its clinical and radiological features are not pathognomonic. Here, we report a case of COC in a 45 years old male patient with a long standing swelling.

Research paper thumbnail of Principle and Techniques of Immunohistochemistry – a Review

Immunohistochemistry is a technique for identifying cellular or tissue constituents (antigens) by... more Immunohistochemistry is a technique for identifying cellular or tissue constituents (antigens) by means of antigen-antibody interactions, the site of antibody binding being identified by direct labelling of the antibody, or by use of secondary labelling method. Although histological analysis of Haematoxylin & Eosin stained tissue sections remains at the core of the practice of head and neck surgical pathology, immunohistochemistry has become a powerful tool in the armamentarium of the pathologist. The selection of antibodies for the immunohistochemical testing is made on the basis of their tumor specificity and the likelihood that they will react with the tumor under evaluation. IHC is a well-established ancillary technique to facilitate the diagnosis of infectious and neoplastic processes in animals. Immunohistochemical studies have traditionally focused on markers of specific cell and/or tumour type as aids in the diagnosis of specific tumours.