Prerna Bhardwaj - Academia.edu (original) (raw)

Papers by Prerna Bhardwaj

Evidence-Based Complementary and Alternative Medicine

Fresh fruit and vegetables are highly utilized commodities by health-conscious consumers and repr... more Fresh fruit and vegetables are highly utilized commodities by health-conscious consumers and represent a prominent segment in the functional and nutritional food sector. However, food processing is causing significant loss of nutritional components, and the generation of waste is creating serious economic and environmental problems. Fruit and vegetables encompass husk, peels, pods, pomace, seeds, and stems, which are usually discarded, despite being known to contain potentially beneficial compounds, such as carotenoids, dietary fibers, enzymes, and polyphenols. The emerging interest in the food industry in the nutritional and biofunctional constituents of polyphenols has prompted the utilization of fruit and vegetable waste for developing enriched and functional foods, with applications in the pharmaceutical industry. Moreover, the utilization of waste for developing diverse and crucial bioactive commodities is a fundamental step in sustainable development. Furthermore, it provides ...

Journal of Nanomaterials

Metal nanoparticles (MNPs) are popular in different research fields due to their unique physical ... more Metal nanoparticles (MNPs) are popular in different research fields due to their unique physical and chemical properties and superior antimicrobial, anticancer, antioxidant, larvicidal, and catalytic potentials. Although conventional wet methods like colloidal synthesis, calcination, and spark ablation for synthesizing MNPs are effective, their synthesis uses an array of reducing and stabilizing agents and gases, making the process tedious. Additionally, metal nanoparticles induce oxidative stress through reactive oxygen species (ROS), showing high toxicity. Research and development in green chemistry have gained momentum and massive attention because of being efficient, clean, economical, environment-friendly, and free of hazardous byproducts. Recently, seed extracts in-lieu of chemical stabilizers and reducing agents have become popular because of the single-step green synthesis of MNPs. Seeds provide the researchers with a cost-effective alternate to other biological methods due ...

Artefatos utilizados para coleta e análise de dados do artigo: Bruna Ferreira,, Marcos Kalinowski... more Artefatos utilizados para coleta e análise de dados do artigo: Bruna Ferreira,, Marcos Kalinowski, Marcos V. C. Gomes,, Marcelo C. Marques, and Hélio Lopes,, Simone D. J. Barbosa. 2021. Investigating ProblemDefinition and End-User Involvement in Agile Projects that Use Lean In-ceptions. InSBQS '21: 35th Brazilian Symposium on Software Quality ACM

Natural Resources for Human Health, 2022

Postharvest losses from fungal pathogens to essential fruits and vegetables are enormous and alar... more Postharvest losses from fungal pathogens to essential fruits and vegetables are enormous and alarming. Orthodox synthetic fungicides are being used as a regular practice to restrict these losses. However, now by knowing the hazards of these chemical-based fungicides, the situation demands alternative green technology. Consequently, many angiosperms plant extracts have been evaluated for their antifungal nature and achieved substantial success. However, the second most prevalent flora on land, i.e. bryophytes, have been scarcely used and somewhat remain neglected besides their remarkable thallus organization, water relations and antimicrobial potential. For postharvest fungus control, these bryophytes, the first land plants' extracts to be researched and promoted due to concerns about drug resistance, nephrotoxicity and biomagnification related to current synthetic fungicides. Since these amphibious plants have their unique protective mechanism against fungal or bacterial attacks...

Science, Technology and Advanced Application of Supercapacitors [Working Title], 2018

Supercapacitor is an emerging technology that promises to play an advance role in new generation ... more Supercapacitor is an emerging technology that promises to play an advance role in new generation electronic devices and systems. Carbon (activated carbon, graphene and carbon nanotube) have attracted tremendous attention for their potential applications in supercapacitor technologies due to their excellent mechanical strength, good electrical conductivity, high electron mobilities, excellent chemical stability in acidic and basic medium, good thermal stability in wide range of temperature, various morphological structures, and large specific surface area. This chapter aims to assess the current status of carbon nanomaterials and their composites for supercapacitor application by discussing the literature in this field and presenting a perspective for future research in supercapacitor technologies.

International Journal of Biological & Pharmaceutical Research

Populus ciliata Wall. ex Royle is a large deciduous, indigenous, dioecious native tree of Himacha... more Populus ciliata Wall. ex Royle is a large deciduous, indigenous, dioecious native tree of Himachal Pradesh. Sex chromosomes are not identified in this species and at juvenile stage, male and female trees do not reveal any significant difference in growth and other related characteristics. At maturity male and female trees are different from each other on the basis of biomass, growth rate and habitat etc. Near habitation, propagation of male plants is recommended because seed production cause many health problems. Therefore some reliable and quick methods need to be developing for sex identification. The present study deals with the development of isozyme and RAPD marker for gender determination. The isozyme analysis conducted with seven enzyme systems (peroxidase, esterase, malate dehydrogenase, alcohol dehydrogenase, catalase, ribulosebisphosphate carboxilase and acid phosphatase), two enzymes peroxidase and esterase successfully showed the differentiation between male and female genotypes. Peroxidase enzyme produced one female specific band where as esterase enzyme produce one male and one female specific band which distinguished the female genotype from the male genotype. Out of ten polymorphic random primers used, one primer (OPK-20) gave significant difference between male and female trees and identified as female specific marker (OPK-20 400 , OPK-20 500 and OPK-20 800). All these identified markers can be used to distinguish the sex of P. ciliata at an early stage.

Journal of Fungi, 2021

The changing climatic conditions have led to the concurrent emergence of virulent microbial patho... more The changing climatic conditions have led to the concurrent emergence of virulent microbial pathogens that attack crop plants and exhibit yield and quality deterring impacts on the affected crop. To counteract, the widespread infections of fungal pathogens and post-harvest diseases it is highly warranted to develop sustainable techniques and tools bypassing traditional agriculture practices. Nanotechnology offers a solution to the problems in disease management in a simple lucid way. These technologies are revolutionizing the scientific/industrial sectors. Likewise, in agriculture, the nano-based tools are of great promise particularly for the development of potent formulations ensuring proper delivery of agrochemicals, nutrients, pesticides/insecticides, and even growth regulators for enhanced use efficiency. The development of novel nanocomposites for improved management of fungal diseases can mitigate the emergence of resilient and persistent fungal pathogens and the loss of crop...

Oxidative Medicine and Cellular Longevity, 2021

Benincasa hispida (Thunb.) Cogn. (Cucurbitaceae) is an annual climbing plant, native to Asia with... more Benincasa hispida (Thunb.) Cogn. (Cucurbitaceae) is an annual climbing plant, native to Asia with multiple therapeutic uses in traditional medicine. This updated review is aimed at discussing the ethnopharmacological, phytochemical, pharmacological properties, and molecular mechanisms highlighted in preclinical experimental studies and toxicological safety to evaluate the therapeutic potential of this genus. The literature from PubMed, Google Scholar, Elsevier, Springer, Science Direct, and database was analyzed using the basic keyword “Benincasa hispida.” Other searching strategies, including online resources, books, and journals, were used. The taxonomy of the plant has been made by consulting “The Plant List”. The results showed that B. hispida has been used in traditional medicine to treat neurological diseases, kidney disease, fever, and cough accompanied by thick mucus and to fight intestinal worms. The main bioactive compounds contained in Benincasa hispida have cytotoxic, an...

Molecules, 2021

Conifers have long been recognized for their therapeutic potential in different disorders. Alkalo... more Conifers have long been recognized for their therapeutic potential in different disorders. Alkaloids, terpenes and polyphenols are the most abundant naturally occurring phytochemicals in these plants. Here, we provide an overview of the phytochemistry and related commercial products obtained from conifers. The pharmacological actions of different phytochemicals present in conifers against bacterial and fungal infections, cancer, diabetes and cardiovascular diseases are also reviewed. Data obtained from experimental and clinical studies performed to date clearly underline that such compounds exert promising antioxidant effects, being able to inhibit cell damage, cancer growth, inflammation and the onset of neurodegenerative diseases. Therefore, an attempt has been made with the intent to highlight the importance of conifer-derived extracts for pharmacological purposes, with the support of relevant in vitro and in vivo experimental data. In short, this review comprehends the informati...

Phytotherapy Research, 2020

Essential oils (EOs) are regarded as alternative therapeutic agents for many diseases. In phytoth... more Essential oils (EOs) are regarded as alternative therapeutic agents for many diseases. In phytotherapy research areas, it is now well reported that conifers are the rich source of EOs. This review aims to update information on the biological sources and the best extraction processes of the significant constituents along with the traditional and therapeutic properties of the EOs from selected conifers of Himachal Pradesh, Northwestern Himalaya. In the present review, ten conifer species of high values have been selected. Results from several studies suggest that the conifers contain monoterpenes, sesquiterpenes, diterpenes, ketones, alcohols, and esters, which are used in medicines, food products, and cosmetics as well as other commercial and industrial products. Traditionally, the EOs from the conifers have been reported to be used against fever, cough, bronchitis, skin diseases, gastrointestinal disorders, and asthma. The pharmacological studies suggest that these EOs can be used as antirheumatic, antiseptic, antispasmodic, anticancer, anti‐inflammatory, antitoxic, aphrodisiac, and astringent agents. It is, therefore, concluded that the EOs from the conifers might be one of the promising tools for the treatment of various diseases. Extensive research is required to ascertain the efficacy of the EOs from unstudied conifers.

International Journal of Molecular Sciences, 2020

The use of metallic nanoparticles in engineering and biomedicine disciplines has gained considera... more The use of metallic nanoparticles in engineering and biomedicine disciplines has gained considerable attention. Scientists are exploring new synthesis protocols of these substances considering their small size and lucrative antimicrobial potential. Among the most economical techniques of synthesis of metallic nanoparticles via chemical routes, which includes the use of chemicals as metal reducing agents, is considered to generate nanoparticles possessing toxicity and biological risk. This limitation of chemically synthesized nanoparticles has engendered the exploration for the ecofriendly synthesis process. Biological or green synthesis approaches have emerged as an effective solution to address the limitations of conventionally synthesized nanoparticles. Nanoparticles synthesized via biological entities obtained from plant extracts exhibit superior effect in comparison to chemical methods. Recently, conifer extracts have been found to be effective in synthesizing metallic nanoparti...

Molecules, 2020

Fruits and vegetables are the highly used food products amongst the horticultural crops. These it... more Fruits and vegetables are the highly used food products amongst the horticultural crops. These items are consumed uncooked, nominally cooked or fully cooked, according to their nature and cooking process. With the change in diet habits and rising population, the production, as well as the processing of horticultural crops, has exponentially improved to meet its increasing demand. A large amount of peel waste is generated from fruit and vegetable-based industries and household kitchen and has led to a big nutritional and economic loss and environmental problems. Processing of fruits and vegetables alone generates a significant waste, which amounts to 25–30% of the total product. Most common wastes include pomace, peels, rind and seeds, which are highly rich in valuable bioactive compounds such as carotenoids, enzymes, polyphenols, oils, vitamins and many other compounds. These bioactive compounds show their application in various industries such as food to develop edible films, food ...

Journal of Fungi, 2020

Research and innovation in nanoparticles (NPs) synthesis derived from biomaterials have gained mu... more Research and innovation in nanoparticles (NPs) synthesis derived from biomaterials have gained much attention due to their unique characteristics, such as low-cost, easy synthesis methods, high water solubility, and eco-friendly nature. NPs derived from macrofungi, including various mushroom species, such as Agaricus bisporus, Pleurotus spp., Lentinus spp., and Ganoderma spp. are well known to possess high nutritional, immune-modulatory, antimicrobial (antibacterial, antifungal and antiviral), antioxidant, and anticancerous properties. Fungi have intracellular metal uptake ability and maximum wall binding capacity; because of which, they have high metal tolerance and bioaccumulation ability. Primarily, two methods have been comprehended in the literature to synthesize metal NPs from macrofungi, i.e., the intracellular method, which refers to NP synthesis inside fungal cells by transportation of ions in the presence of enzymes; and the extracellular method, which refers to the treatm...

International Journal of Molecular Sciences