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Research paper thumbnail of Extraction and Identification of Various Phytopharmaceutical Constituent of Catharanthus Roseus L. (Alba) Leaves

Plant Archives, Sep 30, 2023

Catharanthus roseus, Madagascar periwinkle has an undaunted spirit with marvellous and manifold p... more Catharanthus roseus, Madagascar periwinkle has an undaunted spirit with marvellous and manifold property to combat against the disease. In traditional and herbal medicine, the periwinkle has been used in prevention of diabetes, cancer, stomach-ache, malaria, sore-throat, eye-irritation, skin problem, kidney, liver, cardiovascular disease, relieving muscle pain, depression also used for applying to wasp stings and heal wounds. Root paste is used in septic wounds, root decoction is used in fever, leaves are used in menorrhagia, leaf juice is used in blood dysentery. Many drugs, flavouring agent, beauty and food products are sold today comprised of naturally produced compounds called secondary metabolites. Thousands of years, medicinal plants have been used as safe therapeutic in worldwide. Now a day's Pharmaceutical companies start processing of medicinal plants by using extraction of active components. In this study plant parts like leaves of Catharanthus roseus L. (Alba) were air dried and powdered separately. Varieties of flavonoids and phytosterols isolated by TLC. Dried plant leaves extract of flavonoids and phytosterols are dissolved in 10mg/ml ethanol and take 3 to 3.5ml sample for GCMS analysis. According to GCMS analysis of plant sample we have found some novel compound named Hentriacontane, 1-Heptacosanol, Ethyl 9 hexadecenoate, 2,6 octadien, Trimethylsilyl ester, Ethyl oleate, Ethyl nonadecanonoate, 9,10 Anthraquinone etc. having ant-inflammatory, antimicrobial and anti-diarrheal property which are useful in drug making for various disease.

Research paper thumbnail of Antimicrobial Attributes in Vivo Grown Catharanthus Roseus Linn

Objective:Identification of antimicrobial attributes in vivo grown Catharanthus roseus in presenc... more Objective:Identification of antimicrobial attributes in vivo grown Catharanthus roseus in presence of polar and non polar solvent and performance of Catharanthus roseus plant extracts i.e. root, stem, plant, flower against different bacteria's and fungi's micro-organisms. Method:-Antimicrobial activity of C. roseus was studied in presence of polar and non polar solvent i.e. methanol(CH3-OH) and chloroform(CHCl3) extracts against four bacterial i.e. Bacillus subtilis(B. subtilis), Staphylococcus aureus(S. aureus), Escherichia coli(E. coli), Streptomyces griseus(S. griseus) and four fungal i.e. Fusarium oxysporum(F.oxysporum), Trichoderma reesei (T. reesei), Penicillium funiculosum (P.funiculosum), Aspergillus niger(A. Niger) strains were selected for the primary screening. Results:By measuring the zone of inhibition using agar well diffusion method it have been observed that both polar(methanol) and non polar(chloroform) solvent extracts showed a very strong antimicrobial act...

Research paper thumbnail of A Study on Potential Phytopharmaceuticals Assets in Catharanthus roseus L. (Alba)

Herbal medicinal plants are boon for human being as treatment of existing and new diseases are be... more Herbal medicinal plants are boon for human being as treatment of existing and new diseases are being developed either direct or indirect usage of plants. But availability of such plants and their properties also play an important role. Catharanthus roseus is a very important medicinal herb in this direction as availability and its property both are fortunate thing for humankind. This plant is used in treatment of several diseases like diabetes, cancer, high blood pressure, asthma, inflammation, dysentery, brain imbalance, angiogenesis, malaria and other diseases that occur due to potent micro organisms. Though it's a native of Madagascar but it is found most parts of the world. It is also appreciated for its long flowering period throughout the year. Its roots, leaves, stems and flowers having active constituents to inhibit the growth of disease and other micro organism. Extracts from the dried or wet flowers and leaves of plants are applied as a paste on wounds in some rural co...

Research paper thumbnail of A Study on Potential Phytopharmaceuticals

Herbal medicinal plants are boon for human being as treatment of existing and new diseases are be... more Herbal medicinal plants are boon for human being as treatment of existing and new diseases are being developed either direct or indirect usage of plants. But availability of such plants and their properties also play an important role. Catharanthus roseus is a very important medicinal herb in this direction as availability and its property both are fortunate thing for humankind. This plant is used in treatment of several diseases like diabetes, cancer, high blood pressure, asthma, inflammation, dysentery, brain imbalance, angiogenesis, malaria and other diseases that occur due to potent micro organisms. Though it's a native of Madagascar but it is found most parts of the world. It is also appreciated for its long flowering period throughout the year. Its roots, plant stems and flowers having active constituents to inhibit the growth of disease and other micro organism. Extracts from the dried or wet flowers and leaves of plants are applied as a paste on wounds in some rural comm...

Research paper thumbnail of Identification of Cost Effective Drug Through In-Silico Approach of Catharanthus Roseus Plant Ligand-Receptor Docking for Type 2 Diabetes Niddm

World Journal of Pharmacy and Pharmaceutical Sciences

Research paper thumbnail of Identification of Cost Effective Drug Through In-Silico Approach of Catharanthus Roseus Plant Ligand-Receptor Docking for Type 2 Diabetes Niddm

World Journal of Pharmacy and Pharmaceutical Sciences

Research paper thumbnail of Extraction and Identification of Various Phytopharmaceutical Constituent of Catharanthus Roseus L. (Alba) Leaves

Plant Archives, Sep 30, 2023

Catharanthus roseus, Madagascar periwinkle has an undaunted spirit with marvellous and manifold p... more Catharanthus roseus, Madagascar periwinkle has an undaunted spirit with marvellous and manifold property to combat against the disease. In traditional and herbal medicine, the periwinkle has been used in prevention of diabetes, cancer, stomach-ache, malaria, sore-throat, eye-irritation, skin problem, kidney, liver, cardiovascular disease, relieving muscle pain, depression also used for applying to wasp stings and heal wounds. Root paste is used in septic wounds, root decoction is used in fever, leaves are used in menorrhagia, leaf juice is used in blood dysentery. Many drugs, flavouring agent, beauty and food products are sold today comprised of naturally produced compounds called secondary metabolites. Thousands of years, medicinal plants have been used as safe therapeutic in worldwide. Now a day's Pharmaceutical companies start processing of medicinal plants by using extraction of active components. In this study plant parts like leaves of Catharanthus roseus L. (Alba) were air dried and powdered separately. Varieties of flavonoids and phytosterols isolated by TLC. Dried plant leaves extract of flavonoids and phytosterols are dissolved in 10mg/ml ethanol and take 3 to 3.5ml sample for GCMS analysis. According to GCMS analysis of plant sample we have found some novel compound named Hentriacontane, 1-Heptacosanol, Ethyl 9 hexadecenoate, 2,6 octadien, Trimethylsilyl ester, Ethyl oleate, Ethyl nonadecanonoate, 9,10 Anthraquinone etc. having ant-inflammatory, antimicrobial and anti-diarrheal property which are useful in drug making for various disease.

Research paper thumbnail of Antimicrobial Attributes in Vivo Grown Catharanthus Roseus Linn

Objective:Identification of antimicrobial attributes in vivo grown Catharanthus roseus in presenc... more Objective:Identification of antimicrobial attributes in vivo grown Catharanthus roseus in presence of polar and non polar solvent and performance of Catharanthus roseus plant extracts i.e. root, stem, plant, flower against different bacteria's and fungi's micro-organisms. Method:-Antimicrobial activity of C. roseus was studied in presence of polar and non polar solvent i.e. methanol(CH3-OH) and chloroform(CHCl3) extracts against four bacterial i.e. Bacillus subtilis(B. subtilis), Staphylococcus aureus(S. aureus), Escherichia coli(E. coli), Streptomyces griseus(S. griseus) and four fungal i.e. Fusarium oxysporum(F.oxysporum), Trichoderma reesei (T. reesei), Penicillium funiculosum (P.funiculosum), Aspergillus niger(A. Niger) strains were selected for the primary screening. Results:By measuring the zone of inhibition using agar well diffusion method it have been observed that both polar(methanol) and non polar(chloroform) solvent extracts showed a very strong antimicrobial act...

Research paper thumbnail of A Study on Potential Phytopharmaceuticals Assets in Catharanthus roseus L. (Alba)

Herbal medicinal plants are boon for human being as treatment of existing and new diseases are be... more Herbal medicinal plants are boon for human being as treatment of existing and new diseases are being developed either direct or indirect usage of plants. But availability of such plants and their properties also play an important role. Catharanthus roseus is a very important medicinal herb in this direction as availability and its property both are fortunate thing for humankind. This plant is used in treatment of several diseases like diabetes, cancer, high blood pressure, asthma, inflammation, dysentery, brain imbalance, angiogenesis, malaria and other diseases that occur due to potent micro organisms. Though it's a native of Madagascar but it is found most parts of the world. It is also appreciated for its long flowering period throughout the year. Its roots, leaves, stems and flowers having active constituents to inhibit the growth of disease and other micro organism. Extracts from the dried or wet flowers and leaves of plants are applied as a paste on wounds in some rural co...

Research paper thumbnail of A Study on Potential Phytopharmaceuticals

Herbal medicinal plants are boon for human being as treatment of existing and new diseases are be... more Herbal medicinal plants are boon for human being as treatment of existing and new diseases are being developed either direct or indirect usage of plants. But availability of such plants and their properties also play an important role. Catharanthus roseus is a very important medicinal herb in this direction as availability and its property both are fortunate thing for humankind. This plant is used in treatment of several diseases like diabetes, cancer, high blood pressure, asthma, inflammation, dysentery, brain imbalance, angiogenesis, malaria and other diseases that occur due to potent micro organisms. Though it's a native of Madagascar but it is found most parts of the world. It is also appreciated for its long flowering period throughout the year. Its roots, plant stems and flowers having active constituents to inhibit the growth of disease and other micro organism. Extracts from the dried or wet flowers and leaves of plants are applied as a paste on wounds in some rural comm...

Research paper thumbnail of Identification of Cost Effective Drug Through In-Silico Approach of Catharanthus Roseus Plant Ligand-Receptor Docking for Type 2 Diabetes Niddm

World Journal of Pharmacy and Pharmaceutical Sciences

Research paper thumbnail of Identification of Cost Effective Drug Through In-Silico Approach of Catharanthus Roseus Plant Ligand-Receptor Docking for Type 2 Diabetes Niddm

World Journal of Pharmacy and Pharmaceutical Sciences