Guanming Qiao - Academia.edu (original) (raw)

Guanming Qiao

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Papers by Guanming Qiao

Research paper thumbnail of Multiscale Computational Model Predicts Mouse Skin Kinematics Under Tensile Loading

Journal of Biomechanical Engineering, 2021

Skin is a complex tissue whose biomechanical properties are generally understood in terms of an i... more Skin is a complex tissue whose biomechanical properties are generally understood in terms of an incompressible material whose microstructure undergoes affine deformations. A growing number of experiments, however, have demonstrated that skin has a high Poisson’s ratio, substantially decreases in volume during uniaxial tensile loading, and demonstrates collagen fiber kinematics that are not affine with local deformation. In order to better understand the mechanical basis for these properties, we constructed multiscale mechanical models (MSM) of mouse skin based on microstructural multiphoton microscopy imaging of the dermal microstructure acquired during mechanical testing. Three models that spanned the cases of highly aligned, moderately aligned, and nearly random fiber networks were examined and compared to the data acquired from uniaxially stretched skin. Our results demonstrate that MSMs consisting of networks of matched fiber organization can predict the biomechanical behavior o...

Research paper thumbnail of SABER: Identifying SimilAr BEhavioR for Program Comprehension

Modern software engineering practices rely on program comprehension as the most basic underlying ... more Modern software engineering practices rely on program comprehension as the most basic underlying component for improving developer productivity and software reliability. Software developers are often tasked to work with unfamiliar code in order to remove security vulnerabilities, port and refactor legacy code, and enhance software with new features desired by users. Automatic identification of behavioral clones, or behaviorally-similar code, is one program comprehension technique that can provide developers with assistance. The idea is to identify other code that “does the same thing” and that may be more intuitive; better documented; or familiar to the developer, to help them understand the code at hand. Unlike the detection of syntactic or structural code clones, behavioral clone detection requires executing workloads or test cases to find code that executes similarly on the same inputs. However, a key problem in behavioral clone detection that has not received adequate attention ...

Research paper thumbnail of Multiscale Computational Model Predicts Mouse Skin Kinematics Under Tensile Loading

Journal of Biomechanical Engineering, 2021

Skin is a complex tissue whose biomechanical properties are generally understood in terms of an i... more Skin is a complex tissue whose biomechanical properties are generally understood in terms of an incompressible material whose microstructure undergoes affine deformations. A growing number of experiments, however, have demonstrated that skin has a high Poisson’s ratio, substantially decreases in volume during uniaxial tensile loading, and demonstrates collagen fiber kinematics that are not affine with local deformation. In order to better understand the mechanical basis for these properties, we constructed multiscale mechanical models (MSM) of mouse skin based on microstructural multiphoton microscopy imaging of the dermal microstructure acquired during mechanical testing. Three models that spanned the cases of highly aligned, moderately aligned, and nearly random fiber networks were examined and compared to the data acquired from uniaxially stretched skin. Our results demonstrate that MSMs consisting of networks of matched fiber organization can predict the biomechanical behavior o...

Research paper thumbnail of SABER: Identifying SimilAr BEhavioR for Program Comprehension

Modern software engineering practices rely on program comprehension as the most basic underlying ... more Modern software engineering practices rely on program comprehension as the most basic underlying component for improving developer productivity and software reliability. Software developers are often tasked to work with unfamiliar code in order to remove security vulnerabilities, port and refactor legacy code, and enhance software with new features desired by users. Automatic identification of behavioral clones, or behaviorally-similar code, is one program comprehension technique that can provide developers with assistance. The idea is to identify other code that “does the same thing” and that may be more intuitive; better documented; or familiar to the developer, to help them understand the code at hand. Unlike the detection of syntactic or structural code clones, behavioral clone detection requires executing workloads or test cases to find code that executes similarly on the same inputs. However, a key problem in behavioral clone detection that has not received adequate attention ...

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