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Papers by Qing Chen
Plant Physiology, 1995
Kinetic aspects of ethylene-mediated signal transduction leading to seedlinggrowth inhibition and... more Kinetic aspects of ethylene-mediated signal transduction leading to seedlinggrowth inhibition and chitinase induction in Arabidopsis were investigated by the introduction of defined mutations in components of these pathways. Dose-response analysis of wild-type responses indicated that the rate-limiting steps for seedling responses and Arabidopsis basic-chitinase induction displayed Michaelis-Menten kinetics with apparent dissociation constants of the response (K,) of 0.1 and 1.4 pL 1-' ethylene, respectively. In the ethylene-insensitive efrl-l and ein2-32 mutant lines, both Arabidopsis basíc-chitinase induction and seedling-growth responses were completely disrupted, whereas the weaker efrl-2 allele eliminated the chitinase-induction response but only partially disrupted the seedling responses. A heterologous reporter gene containing the chitinase promoter from bean (bean basic-chitinase-/3-glucuronidase) displayed subsensitive kinetics (K, 120 pL L-' ethylene) compared to the response of the endogenous basic-chitinase response (K, 1.4 p L L-' ethylene). A model for ethylene signal transduction that accounts for the observed variations in ethylene dose-response relationships is presented. The relationship between the model and the biochemical mechanisms of well-characterized signal-transduction systems in animals is discussed.
A robust quantizer is developed for encoding a variety of memoryless sources and transmission ove... more A robust quantizer is developed for encoding a variety of memoryless sources and transmission over the binary symmetric channel (BSC). The system combines channel optimized scalar quantization (COSQ) with all-pass filtering, the latter performed using a binary phase-scrambling/descrambling method. Applied to a broad class of sources, the robust quantizer achieves the same performance as the Gaussian COSQ for the memoryless Gaussian source. This quantizer is used for image coding for transmission over a BSC. An explicit error protection code is used only to protect the side information. The PSNR performance degrades gracefully as the channel bit error rate increases
IEEE Transactions on Image Processing, 1998
A robust quantizer is developed for encoding memoryless sources and transmission over the binary ... more A robust quantizer is developed for encoding memoryless sources and transmission over the binary symmetric channel (BSC). The system combines channel optimized scalar quantization (COSQ) with all-pass filtering, the latter performed using a binary phase-scrambling/descrambling method. Applied to a broad class of sources, the robust quantizer achieves the same performance as the Gaussian COSQ for the memoryless Gaussian source. This quantizer is used in image coding for transmission over a BSC. The peak signal-to-noise ratio (PSNR) performance degrades gracefully as the channel bit error rate increases
Kidney International, 2003
Conclusion. BMP-7 partially reversed diabetic-induced kid-Bone morphogenic protein-7 (BMP-7), a n... more Conclusion. BMP-7 partially reversed diabetic-induced kid-Bone morphogenic protein-7 (BMP-7), a novel therapy for ney hypertrophy, restoring GFR, urine albumin excretion, and diabetic nephropathy. glomerular histology toward normal. Restoration of BMP-7 Background. Bone morphogenic protein-7 (BMP-7), an esexpression was associated with a successful repair reaction and sential developmental renal morphogen, is a secreted differena reversal of the ill-fated injury response. tiation factor of the adult collecting duct. It activates receptors in the collecting duct, distal nephron, proximal tubule, and glomerulus. BMP-7 is therapeutic in tubulointerstitial nephritis raising the question of broader efficacy in chronic kidney dis-Recent studies have made the surprising observation ease (CKD).
Plant Physiology, 1995
Kinetic aspects of ethylene-mediated signal transduction leading to seedlinggrowth inhibition and... more Kinetic aspects of ethylene-mediated signal transduction leading to seedlinggrowth inhibition and chitinase induction in Arabidopsis were investigated by the introduction of defined mutations in components of these pathways. Dose-response analysis of wild-type responses indicated that the rate-limiting steps for seedling responses and Arabidopsis basic-chitinase induction displayed Michaelis-Menten kinetics with apparent dissociation constants of the response (K,) of 0.1 and 1.4 pL 1-' ethylene, respectively. In the ethylene-insensitive efrl-l and ein2-32 mutant lines, both Arabidopsis basíc-chitinase induction and seedling-growth responses were completely disrupted, whereas the weaker efrl-2 allele eliminated the chitinase-induction response but only partially disrupted the seedling responses. A heterologous reporter gene containing the chitinase promoter from bean (bean basic-chitinase-/3-glucuronidase) displayed subsensitive kinetics (K, 120 pL L-' ethylene) compared to the response of the endogenous basic-chitinase response (K, 1.4 p L L-' ethylene). A model for ethylene signal transduction that accounts for the observed variations in ethylene dose-response relationships is presented. The relationship between the model and the biochemical mechanisms of well-characterized signal-transduction systems in animals is discussed.
A robust quantizer is developed for encoding a variety of memoryless sources and transmission ove... more A robust quantizer is developed for encoding a variety of memoryless sources and transmission over the binary symmetric channel (BSC). The system combines channel optimized scalar quantization (COSQ) with all-pass filtering, the latter performed using a binary phase-scrambling/descrambling method. Applied to a broad class of sources, the robust quantizer achieves the same performance as the Gaussian COSQ for the memoryless Gaussian source. This quantizer is used for image coding for transmission over a BSC. An explicit error protection code is used only to protect the side information. The PSNR performance degrades gracefully as the channel bit error rate increases
IEEE Transactions on Image Processing, 1998
A robust quantizer is developed for encoding memoryless sources and transmission over the binary ... more A robust quantizer is developed for encoding memoryless sources and transmission over the binary symmetric channel (BSC). The system combines channel optimized scalar quantization (COSQ) with all-pass filtering, the latter performed using a binary phase-scrambling/descrambling method. Applied to a broad class of sources, the robust quantizer achieves the same performance as the Gaussian COSQ for the memoryless Gaussian source. This quantizer is used in image coding for transmission over a BSC. The peak signal-to-noise ratio (PSNR) performance degrades gracefully as the channel bit error rate increases
Kidney International, 2003
Conclusion. BMP-7 partially reversed diabetic-induced kid-Bone morphogenic protein-7 (BMP-7), a n... more Conclusion. BMP-7 partially reversed diabetic-induced kid-Bone morphogenic protein-7 (BMP-7), a novel therapy for ney hypertrophy, restoring GFR, urine albumin excretion, and diabetic nephropathy. glomerular histology toward normal. Restoration of BMP-7 Background. Bone morphogenic protein-7 (BMP-7), an esexpression was associated with a successful repair reaction and sential developmental renal morphogen, is a secreted differena reversal of the ill-fated injury response. tiation factor of the adult collecting duct. It activates receptors in the collecting duct, distal nephron, proximal tubule, and glomerulus. BMP-7 is therapeutic in tubulointerstitial nephritis raising the question of broader efficacy in chronic kidney dis-Recent studies have made the surprising observation ease (CKD).