Qiong Meng - Academia.edu (original) (raw)
Papers by Qiong Meng
Cancer investigation, Jan 5, 2015
This study aimed to develop and validate the Simplified Chinese Version of the Quality of Life Qu... more This study aimed to develop and validate the Simplified Chinese Version of the Quality of Life Questionnaire for Hepatocellular Carcinoma (the QLQ-HCC18). It was developed by the strict translation procedure of EORTC guidelines, and the psychometrics were evaluated on a sample of 114 patients. The internal consistency Cronbach's α were greater than 0.60 for all domains (exception of Jaundice 0.38), and all test-retest reliability coefficients were greater than 0.80. Four out of eight domains had statistically significant changes with effect size standardized response mean (SRM) ranging from 0.31 to 0.73. The Simplified Chinese version of QLQ-HCC18 demonstrates good validity, reliability, and responsiveness.
Ai zheng = Aizheng = Chinese journal of cancer, 2008
Based on the development of the general module of the system of quality of life instruments for c... more Based on the development of the general module of the system of quality of life instruments for cancer patients (QLICP-GM), this study was to develop and evaluate a quality of life scale for patients with colorectal cancer (QLICP-CR). A quality of life scale for colorectal cancer patients that associated with Chinese cultural background was developed. The data from 110 patients with colorectal cancer were analyzed using statistical description, Pearson Correlation, Cluster analysis, and paired t-student test to assess the instrument. The test-retest reliability for the scale and 5 domains were all above 0.78. Internal consistency alpha for each domain was higher than 0.85 except for the social domain (0.66) and the symptom and side effect domain (0.63). Most of the correlation coefficients between each item and its domains were above 0.6. The differences in the scores of overall scale, general module, special domain, psychological domain, and symptom and side effect domain between p...
Supportive Care in Cancer, 2012
Goals A simplified Chinese version of EORTC QLQ-H&N35 was developed using strict translation proc... more Goals A simplified Chinese version of EORTC QLQ-H&N35 was developed using strict translation procedures according to EORTC translation guidelines. Psychometric properties were evaluated. Patients and methods Three instruments (QLQ-H&N35, QLICP-HN, and FACT-H&N) were used in a sample of 133 patients with head and neck cancer at the time of their admission to the hospital. Each patient was assessed for the second time 1-2 days after hospitalization so that the testretest reliability could be calculated. A sub-sample of patients was sampled and measured for the third time at discharge in order to evaluate the responsiveness. Results Correlation analysis among domains and items of the three instruments showed good construct validity and criterion-related validity. Comparisons of QLQ-H&N35 between treatment groups and age groups supported clinical validity. The internal consistency reliability measured by Cronbach's coefficient α was greater than 0.70 for all multiitem domains, and test-retest reliability coefficients for all domains were greater than 0.80, ranging from 0.88 to 0.95. Score changes between pre-and post-treatment were observed in 6 out of 18 domains, with effect size SRM ranging from 0.27 to 0.87. Conclusions The simplified Chinese version of QLQ-H&N35 demonstrates good validity, reliability, and responsiveness and can be used to measure QOL for Chinese patients with head and neck cancer.
Oncology, 2012
This study aimed to develop and validate the simplified Chinese version of the EORTC Quality of L... more This study aimed to develop and validate the simplified Chinese version of the EORTC Quality of Life Questionnaire for Colorectal Cancer, QLQ-CR38. It was developed by the strict translation procedure of EORTC translation guidelines, including translation, back translation, a pilot test and a cultural adaptation. Three instruments (QLQ-CR38, Quality of Life Instruments for Cancer Patients-Colorectal Cancer, and Functional Assessment of Cancer Therapy-Colorectal) were used on a sample of 110 patients with colorectal cancer at the time of their admission to the hospital and 1-2 days after hospitalization, and a subsample of patients was measured a third time at discharge. The psychometric properties were evaluated by correlational analysis, multi-trait scaling analysis, factor analysis, and t tests. Multi-trait scaling analysis and correlation analysis among domains and items of the three instruments showed good construct validity and criterion-related validity. Cronbach's α and the test-retest reliability coefficients were greater than 0.70 for all domains (except chemotherapy side effects, 0.44 and 0.60, respectively). All domains had statistically significant changes after treatment with the standardized response mean ranging from 0.44 to 2.47. The simplified Chinese version of QLQ-CR38 has good validity, reliability, and responsiveness and can be used to measure the quality of life of Chinese patients with colorectal cancer.
Nonlinear Analysis: Theory, Methods & Applications, 2006
Sufficient and necessary conditions for the bounded oscillation of the second order non-linear ne... more Sufficient and necessary conditions for the bounded oscillation of the second order non-linear neutral delay differential equation
Nonlinear Analysis: Theory, Methods & Applications, 2011
The existence of the nontrivial periodic solutions to the system of delay differential equations ... more The existence of the nontrivial periodic solutions to the system of delay differential equations (1.1)x′(t)=−f(x(t−τ)) is investigated, where x∈RN, f∈C(RN,RN). We prove several new existence results via Morse theory and the Galerkin methods.
Journal of Computational and Applied Mathematics, 2006
The sufficient and necessary conditions for the bounded oscillation of the second order nonlinear... more The sufficient and necessary conditions for the bounded oscillation of the second order nonlinear neutral delay difference equation
International Journal of Mathematics and Mathematical Sciences, 2001
We obtain a solution formula of the differential equation ˙ x(t) + a(t)x(t) + b(t)x(g(t)) = f( t)... more We obtain a solution formula of the differential equation ˙ x(t) + a(t)x(t) + b(t)x(g(t)) = f( t). At the same time, we study its oscillation and asymptotic stability properties. 2000 Mathematics Subject Classification. 34K11.
International Journal of Cancer, 2008
Based on World Health Organization (WHO)'s definition of Quality of Life (QOL) and programmed dec... more Based on World Health Organization (WHO)'s definition of Quality of Life (QOL) and programmed decision procedures, we developed a general module of the System of Quality of Life Instruments for Cancer Patients (QLICP-GM) utilizing focus group discussions, pilot tests of 448 cases and field tests of 600 cases of 5 different cancer patients. The number of items in the final version was reduced to 32 from a 78-item pool. The psychometric properties of the scale were evaluated by indicators such as validity and reliability coefficients, SRM, and statistical methods of correlational analysis, t tests, and structural equation modeling. Correlational and structural equation model analyses indicate good construct validity with RMSEA 0.086, NNFI 0.947 and CFI 0.961. Good criterion-related validity was found when FACT-G was used as the criterion. The test-retest reliability for all domains and the overall scale is above 0.85; the internal consistency a for each domain is higher than 0.70 except of the social function; a and the split-half reliability of the overall scale is 0.88 and 0.93, respectively. The pre-post changes of QOL scores are of statistical significances in 3 domains of physical function, psychological function, common symptoms and side effects, and the overall instrument, with standardized response mean ranging from 0.16 to 0.67. Equivalence tests showed nonequivalence on quality of life score changes of these domains and the overall instrument. Our study shows that the QLICP-GM has good validity, reliability, responsiveness, and can be used as the general module for cancer patients in China. ' 2007 Wiley-Liss, Inc.
Breast Cancer Research and Treatment, 2007
A Simplified Chinese version of the EORTC QLQ-BR53 was evaluated using responses from 233 patient... more A Simplified Chinese version of the EORTC QLQ-BR53 was evaluated using responses from 233 patients with breast cancer in China by assessing the construct and criterion-related validity, internal consistency and test-retest reliability, and responsiveness as measured by score changes of the scales. Internal consistency reliability measured by Cronbach's coefficient alpha is greater than 0.75 for most multi-item scales except cognitive functioning (0.41) and breast symptoms (0.71). Test-retest reliability coefficients for all domains are greater than 0.80 with the exception of physical functioning (0.65), social functioning (0.75), appetite loss (0.75), diarrhea (0.72), and body image (0.72). Correlation and factor analysis among domains and items showed good construct validity for both QLQ-C30 and QLQ-BR23. Score changes over time were observed in most domains except emotional functioning, global health status/QOL, dyspnoea, constipation, diarrhea, financial difficulties, sexual functioning, sexual enjoyment, and breast symptoms. Therefore, the Simplified Chinese version of QLQ-BR53 shows reasonable validity, reliability, and responsiveness and can be used to measure QOL for Chinese patients with breast cancer.
American Journal of Clinical Oncology, 2010
ABSTRACT To develop a self-administered quality of life instrument for patients with liver cancer... more ABSTRACT To develop a self-administered quality of life instrument for patients with liver cancer. The programmed decision procedure, the theory and methodology in developing rating scale were used to establish the instrument. On the basis of the data from 105 liver cancer patients, the psychometric properties of the scale were evaluated by indicators of validity, reliability coefficients, and statistical methods like structural equation modeling. The test-retest coefficients for physical, psychological, symptom/side effects, social domains, and the overall scale are 0.76, 0.86, 0.71, 0.80, and 0.84, respectively. The α coefficients for the above 4 domains are 0.78, 0.81, 0.75, and 0.68, respectively. The correlation analysis and the structural equation model showed good construct validity. The criterion-related was confirmed by using the functional living index-cancer simultaneously. The scale can reflect the changes of patients' quality of life after treatment. The instrument is of good validity, reliability, and responsiveness and has been broadly used in China.
The American Mathematical Monthly, 1983
Cancer investigation, Jan 5, 2015
This study aimed to develop and validate the Simplified Chinese Version of the Quality of Life Qu... more This study aimed to develop and validate the Simplified Chinese Version of the Quality of Life Questionnaire for Hepatocellular Carcinoma (the QLQ-HCC18). It was developed by the strict translation procedure of EORTC guidelines, and the psychometrics were evaluated on a sample of 114 patients. The internal consistency Cronbach's α were greater than 0.60 for all domains (exception of Jaundice 0.38), and all test-retest reliability coefficients were greater than 0.80. Four out of eight domains had statistically significant changes with effect size standardized response mean (SRM) ranging from 0.31 to 0.73. The Simplified Chinese version of QLQ-HCC18 demonstrates good validity, reliability, and responsiveness.
Ai zheng = Aizheng = Chinese journal of cancer, 2008
Based on the development of the general module of the system of quality of life instruments for c... more Based on the development of the general module of the system of quality of life instruments for cancer patients (QLICP-GM), this study was to develop and evaluate a quality of life scale for patients with colorectal cancer (QLICP-CR). A quality of life scale for colorectal cancer patients that associated with Chinese cultural background was developed. The data from 110 patients with colorectal cancer were analyzed using statistical description, Pearson Correlation, Cluster analysis, and paired t-student test to assess the instrument. The test-retest reliability for the scale and 5 domains were all above 0.78. Internal consistency alpha for each domain was higher than 0.85 except for the social domain (0.66) and the symptom and side effect domain (0.63). Most of the correlation coefficients between each item and its domains were above 0.6. The differences in the scores of overall scale, general module, special domain, psychological domain, and symptom and side effect domain between p...
Supportive Care in Cancer, 2012
Goals A simplified Chinese version of EORTC QLQ-H&N35 was developed using strict translation proc... more Goals A simplified Chinese version of EORTC QLQ-H&N35 was developed using strict translation procedures according to EORTC translation guidelines. Psychometric properties were evaluated. Patients and methods Three instruments (QLQ-H&N35, QLICP-HN, and FACT-H&N) were used in a sample of 133 patients with head and neck cancer at the time of their admission to the hospital. Each patient was assessed for the second time 1-2 days after hospitalization so that the testretest reliability could be calculated. A sub-sample of patients was sampled and measured for the third time at discharge in order to evaluate the responsiveness. Results Correlation analysis among domains and items of the three instruments showed good construct validity and criterion-related validity. Comparisons of QLQ-H&N35 between treatment groups and age groups supported clinical validity. The internal consistency reliability measured by Cronbach's coefficient α was greater than 0.70 for all multiitem domains, and test-retest reliability coefficients for all domains were greater than 0.80, ranging from 0.88 to 0.95. Score changes between pre-and post-treatment were observed in 6 out of 18 domains, with effect size SRM ranging from 0.27 to 0.87. Conclusions The simplified Chinese version of QLQ-H&N35 demonstrates good validity, reliability, and responsiveness and can be used to measure QOL for Chinese patients with head and neck cancer.
Oncology, 2012
This study aimed to develop and validate the simplified Chinese version of the EORTC Quality of L... more This study aimed to develop and validate the simplified Chinese version of the EORTC Quality of Life Questionnaire for Colorectal Cancer, QLQ-CR38. It was developed by the strict translation procedure of EORTC translation guidelines, including translation, back translation, a pilot test and a cultural adaptation. Three instruments (QLQ-CR38, Quality of Life Instruments for Cancer Patients-Colorectal Cancer, and Functional Assessment of Cancer Therapy-Colorectal) were used on a sample of 110 patients with colorectal cancer at the time of their admission to the hospital and 1-2 days after hospitalization, and a subsample of patients was measured a third time at discharge. The psychometric properties were evaluated by correlational analysis, multi-trait scaling analysis, factor analysis, and t tests. Multi-trait scaling analysis and correlation analysis among domains and items of the three instruments showed good construct validity and criterion-related validity. Cronbach's α and the test-retest reliability coefficients were greater than 0.70 for all domains (except chemotherapy side effects, 0.44 and 0.60, respectively). All domains had statistically significant changes after treatment with the standardized response mean ranging from 0.44 to 2.47. The simplified Chinese version of QLQ-CR38 has good validity, reliability, and responsiveness and can be used to measure the quality of life of Chinese patients with colorectal cancer.
Nonlinear Analysis: Theory, Methods & Applications, 2006
Sufficient and necessary conditions for the bounded oscillation of the second order non-linear ne... more Sufficient and necessary conditions for the bounded oscillation of the second order non-linear neutral delay differential equation
Nonlinear Analysis: Theory, Methods & Applications, 2011
The existence of the nontrivial periodic solutions to the system of delay differential equations ... more The existence of the nontrivial periodic solutions to the system of delay differential equations (1.1)x′(t)=−f(x(t−τ)) is investigated, where x∈RN, f∈C(RN,RN). We prove several new existence results via Morse theory and the Galerkin methods.
Journal of Computational and Applied Mathematics, 2006
The sufficient and necessary conditions for the bounded oscillation of the second order nonlinear... more The sufficient and necessary conditions for the bounded oscillation of the second order nonlinear neutral delay difference equation
International Journal of Mathematics and Mathematical Sciences, 2001
We obtain a solution formula of the differential equation ˙ x(t) + a(t)x(t) + b(t)x(g(t)) = f( t)... more We obtain a solution formula of the differential equation ˙ x(t) + a(t)x(t) + b(t)x(g(t)) = f( t). At the same time, we study its oscillation and asymptotic stability properties. 2000 Mathematics Subject Classification. 34K11.
International Journal of Cancer, 2008
Based on World Health Organization (WHO)'s definition of Quality of Life (QOL) and programmed dec... more Based on World Health Organization (WHO)'s definition of Quality of Life (QOL) and programmed decision procedures, we developed a general module of the System of Quality of Life Instruments for Cancer Patients (QLICP-GM) utilizing focus group discussions, pilot tests of 448 cases and field tests of 600 cases of 5 different cancer patients. The number of items in the final version was reduced to 32 from a 78-item pool. The psychometric properties of the scale were evaluated by indicators such as validity and reliability coefficients, SRM, and statistical methods of correlational analysis, t tests, and structural equation modeling. Correlational and structural equation model analyses indicate good construct validity with RMSEA 0.086, NNFI 0.947 and CFI 0.961. Good criterion-related validity was found when FACT-G was used as the criterion. The test-retest reliability for all domains and the overall scale is above 0.85; the internal consistency a for each domain is higher than 0.70 except of the social function; a and the split-half reliability of the overall scale is 0.88 and 0.93, respectively. The pre-post changes of QOL scores are of statistical significances in 3 domains of physical function, psychological function, common symptoms and side effects, and the overall instrument, with standardized response mean ranging from 0.16 to 0.67. Equivalence tests showed nonequivalence on quality of life score changes of these domains and the overall instrument. Our study shows that the QLICP-GM has good validity, reliability, responsiveness, and can be used as the general module for cancer patients in China. ' 2007 Wiley-Liss, Inc.
Breast Cancer Research and Treatment, 2007
A Simplified Chinese version of the EORTC QLQ-BR53 was evaluated using responses from 233 patient... more A Simplified Chinese version of the EORTC QLQ-BR53 was evaluated using responses from 233 patients with breast cancer in China by assessing the construct and criterion-related validity, internal consistency and test-retest reliability, and responsiveness as measured by score changes of the scales. Internal consistency reliability measured by Cronbach's coefficient alpha is greater than 0.75 for most multi-item scales except cognitive functioning (0.41) and breast symptoms (0.71). Test-retest reliability coefficients for all domains are greater than 0.80 with the exception of physical functioning (0.65), social functioning (0.75), appetite loss (0.75), diarrhea (0.72), and body image (0.72). Correlation and factor analysis among domains and items showed good construct validity for both QLQ-C30 and QLQ-BR23. Score changes over time were observed in most domains except emotional functioning, global health status/QOL, dyspnoea, constipation, diarrhea, financial difficulties, sexual functioning, sexual enjoyment, and breast symptoms. Therefore, the Simplified Chinese version of QLQ-BR53 shows reasonable validity, reliability, and responsiveness and can be used to measure QOL for Chinese patients with breast cancer.
American Journal of Clinical Oncology, 2010
ABSTRACT To develop a self-administered quality of life instrument for patients with liver cancer... more ABSTRACT To develop a self-administered quality of life instrument for patients with liver cancer. The programmed decision procedure, the theory and methodology in developing rating scale were used to establish the instrument. On the basis of the data from 105 liver cancer patients, the psychometric properties of the scale were evaluated by indicators of validity, reliability coefficients, and statistical methods like structural equation modeling. The test-retest coefficients for physical, psychological, symptom/side effects, social domains, and the overall scale are 0.76, 0.86, 0.71, 0.80, and 0.84, respectively. The α coefficients for the above 4 domains are 0.78, 0.81, 0.75, and 0.68, respectively. The correlation analysis and the structural equation model showed good construct validity. The criterion-related was confirmed by using the functional living index-cancer simultaneously. The scale can reflect the changes of patients' quality of life after treatment. The instrument is of good validity, reliability, and responsiveness and has been broadly used in China.
The American Mathematical Monthly, 1983