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Papers by Qitong ZHENG

Research paper thumbnail of PCA3 gene expression in prostate cancer tissue in a Chinese population: Quantification by real-time FQ-RT-PCR based on exon 3 of PCA3

Experimental and Molecular Pathology, 2010

Prostate cancer (PCa) is the second most common cancer in men, and its incidence is still increas... more Prostate cancer (PCa) is the second most common cancer in men, and its incidence is still increasing. PCA3 is the most prostate cancer specific biomarker. Here we confirmed that both exon 3 and exon 4 are in the prostatespecific region of the PCA3 gene, and established the methodology of real-time fluorescent quantitative RT-PCR (FQ-RT-PCR) detecting PCA3 mRNA with primer spanning exons 1 and 3, and evaluated its clinical utility in a Chinese population. What disclosed that PCA3 mRNA is prostate cancer specific and shows increased expression in prostate cancer. It could be a reliable molecular marker in prostate cancer diagnosis. Exon 3based real-time FQ-RT-PCR may prove useful in prostate cancer diagnosis, given that the associated primer would span only exons 1 and 3, relative to other models spanning exons 1 to 4. A shorter amplicon would not only enhance the efficiency of real-time FQ-RT-PCR, but may also simplify the quantification of PCA3 mRNA.

Research paper thumbnail of Study on Openness of Chinese Stock Market: Comparing with Mature Markets

The maturity and openness of Chinese stock markets can be measured by price impact of other matur... more The maturity and openness of Chinese stock markets can be measured by price impact of other mature stock markets on them. The article uses wavelet analysis to eliminate noise in stock price signal and analyzes to what degree is Shanghai stock market affected by volatility of stock markets of Hong Kong, Tokyo, New York and London by using SVAR (Structural Vector Auto Regression), impulse response analysis and variance decomposition. The results show that Chinese stock markets are becoming more and more mature and open, which are integrated into the global stock market gradually, which can be known from the response of Shanghai Composite Index shocked by the other indices. Among all the mature stock indices in the paper, influence of Dow-Jones Index on Shanghai Composite Index is most significant, followed by FTSE100 Index.

Research paper thumbnail of PCA3 gene expression in prostate cancer tissue in a Chinese population: Quantification by real-time FQ-RT-PCR based on exon 3 of PCA3

Experimental and Molecular Pathology, 2010

Prostate cancer (PCa) is the second most common cancer in men, and its incidence is still increas... more Prostate cancer (PCa) is the second most common cancer in men, and its incidence is still increasing. PCA3 is the most prostate cancer specific biomarker. Here we confirmed that both exon 3 and exon 4 are in the prostatespecific region of the PCA3 gene, and established the methodology of real-time fluorescent quantitative RT-PCR (FQ-RT-PCR) detecting PCA3 mRNA with primer spanning exons 1 and 3, and evaluated its clinical utility in a Chinese population. What disclosed that PCA3 mRNA is prostate cancer specific and shows increased expression in prostate cancer. It could be a reliable molecular marker in prostate cancer diagnosis. Exon 3based real-time FQ-RT-PCR may prove useful in prostate cancer diagnosis, given that the associated primer would span only exons 1 and 3, relative to other models spanning exons 1 to 4. A shorter amplicon would not only enhance the efficiency of real-time FQ-RT-PCR, but may also simplify the quantification of PCA3 mRNA.

Research paper thumbnail of Study on Openness of Chinese Stock Market: Comparing with Mature Markets

The maturity and openness of Chinese stock markets can be measured by price impact of other matur... more The maturity and openness of Chinese stock markets can be measured by price impact of other mature stock markets on them. The article uses wavelet analysis to eliminate noise in stock price signal and analyzes to what degree is Shanghai stock market affected by volatility of stock markets of Hong Kong, Tokyo, New York and London by using SVAR (Structural Vector Auto Regression), impulse response analysis and variance decomposition. The results show that Chinese stock markets are becoming more and more mature and open, which are integrated into the global stock market gradually, which can be known from the response of Shanghai Composite Index shocked by the other indices. Among all the mature stock indices in the paper, influence of Dow-Jones Index on Shanghai Composite Index is most significant, followed by FTSE100 Index.

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