R. Kaya - Academia.edu (original) (raw)
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European Heart Journal, 2013
Bicuspid aortic valve and the aorta Valve anatomy, aortic diameters at different levels, and pres... more Bicuspid aortic valve and the aorta Valve anatomy, aortic diameters at different levels, and presence and degree of valve dysfunction were analysed. Results: Of the 401 FDR recruited: 113 (28.1%) refused the study and 288 (71.9%) underwent screening (mean age: 36.1±19 years; 66.7% males). Twentyone aortic valve abnormalities were encountered: 20 BAV and 1 quadricuspid valve, distributed in 17 of the 90 families, yielding a BAV family prevalence of 18.8% (Table). BAV phenotype was not consistent among probands and positive FDR in 6 of the affected families (35.3%). The prevalence of BAV among the FDR screened was 7.3%, higher than that reported in the general population (0.5-1.0%). The number of FDR required to screen for identifying a new BAV case is 14, in contrast to 100 in the general population. Conclusions: The prevalence of BAV is higher in FDR of BAV patients than in the general population. Discordance between BAV phenotypes within the same family is not rare. Echocardiographic screening of FDR is a useful approach for identifying asymptomatic cases, and should therefore be offered to all FDR of BAV individuals.
The Journal of Organic Chemistry, 1983
... Both the GC and the HPLC were connected with a Varian Vista 401 Data Station. Proton NMR spec... more ... Both the GC and the HPLC were connected with a Varian Vista 401 Data Station. Proton NMR spectra were determined on a Varian EM-360 60-MHz NMR spectrometer. ... Chem. SOC. 1973, 95, 3662. (22) Lerman, B. M.; Galin, FZ; Umanskaya, L. A.; Tolstikov, G. A. J. Org. Chem. ...
The Journal of Organic Chemistry, 1986
Reaction of 8-methylenepentacyclo[5.4.O.Oz~6.O3~1o.O5~g]undecan-ll-one (2) with 1,3-propanedithio... more Reaction of 8-methylenepentacyclo[5.4.O.Oz~6.O3~1o.O5~g]undecan-ll-one (2) with 1,3-propanedithiol and with methanethiol in the presence of F,B.OEh in each case affords mixtures of epimeric cage sulfonium tetrafluoroborates [5a + 5b (81%) and 6a + 6b (88%), respectively]. Similarly, 5-hexen-2-one reacts with 1,3-propanedithiol-F3B.0E~
International Journal of Cardiology, 2012
European Heart Journal, 2013
European Heart Journal, 2013
Bicuspid aortic valve and the aorta Valve anatomy, aortic diameters at different levels, and pres... more Bicuspid aortic valve and the aorta Valve anatomy, aortic diameters at different levels, and presence and degree of valve dysfunction were analysed. Results: Of the 401 FDR recruited: 113 (28.1%) refused the study and 288 (71.9%) underwent screening (mean age: 36.1±19 years; 66.7% males). Twentyone aortic valve abnormalities were encountered: 20 BAV and 1 quadricuspid valve, distributed in 17 of the 90 families, yielding a BAV family prevalence of 18.8% (Table). BAV phenotype was not consistent among probands and positive FDR in 6 of the affected families (35.3%). The prevalence of BAV among the FDR screened was 7.3%, higher than that reported in the general population (0.5-1.0%). The number of FDR required to screen for identifying a new BAV case is 14, in contrast to 100 in the general population. Conclusions: The prevalence of BAV is higher in FDR of BAV patients than in the general population. Discordance between BAV phenotypes within the same family is not rare. Echocardiographic screening of FDR is a useful approach for identifying asymptomatic cases, and should therefore be offered to all FDR of BAV individuals.
The Journal of Organic Chemistry, 1983
... Both the GC and the HPLC were connected with a Varian Vista 401 Data Station. Proton NMR spec... more ... Both the GC and the HPLC were connected with a Varian Vista 401 Data Station. Proton NMR spectra were determined on a Varian EM-360 60-MHz NMR spectrometer. ... Chem. SOC. 1973, 95, 3662. (22) Lerman, B. M.; Galin, FZ; Umanskaya, L. A.; Tolstikov, G. A. J. Org. Chem. ...
The Journal of Organic Chemistry, 1986
Reaction of 8-methylenepentacyclo[5.4.O.Oz~6.O3~1o.O5~g]undecan-ll-one (2) with 1,3-propanedithio... more Reaction of 8-methylenepentacyclo[5.4.O.Oz~6.O3~1o.O5~g]undecan-ll-one (2) with 1,3-propanedithiol and with methanethiol in the presence of F,B.OEh in each case affords mixtures of epimeric cage sulfonium tetrafluoroborates [5a + 5b (81%) and 6a + 6b (88%), respectively]. Similarly, 5-hexen-2-one reacts with 1,3-propanedithiol-F3B.0E~
International Journal of Cardiology, 2012
European Heart Journal, 2013