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Papers by Renti Mahkota

JURNAL ILMIAH KESEHATAN MASYARAKAT : Media Komunikasi Komunitas Kesehatan Masyarakat

Latar Belakang: Kebakaran hutan yang terjadi di Provinsi Bengkulu tahun 2015 menyebabkan adanya p... more Latar Belakang: Kebakaran hutan yang terjadi di Provinsi Bengkulu tahun 2015 menyebabkan adanya pencemaran udara baik di dalam maupun di luar ruangan. Hal ini juga mengakibatkan meningkatnya kejadian ISPA pada balita. Tujuan penelitian ini adalah untuk mengetahui determinan kejadian ISPA pada balita di Kota Bengkulu saat kebakaran hutan tahun 2015. Metode: Metode penelitian yang digunakan adalah case control. Kasus merupakan balita yang berkunjung ke Puskesmas Kecamatan dan didiagnosa menderita ISPA dan kontrol adalah dua balita tetangga kasus yang ditemui pertama kali. Hasil: Hasil analisis menunjukkan bahwa jenis atap (OR: 2,79; 95% CI: 1,36-5,69), ventilasi (OR: 2,60; 95% CI: 1,39-4,84), kepadatan hunian (OR: 2,14; 95% CI: 1,07-4,28), dan asap bahan bakar memasak (OR: 4,14; 95% CI: 1,56-10,9) memiliki hubungan yang kuat terhadap ISPA. Kesimpulan: Jadi, ada hubungan antara kondisi fisik rumah, kepadatan hunian dan pajanan asap terhadap kejadian ISPA pada Balita setelah dikontrol...

Jurnal Epidemiologi Kesehatan Indonesia

Penyakit stroke menjadi salah satu penyebab kematian tertinggidan merupakan penyumbang ketiga kec... more Penyakit stroke menjadi salah satu penyebab kematian tertinggidan merupakan penyumbang ketiga kecacatan secara global.Jenis stroke yang paling umum terjadi di Indonesia adalah strokeiskemik. Sebagian besar penderita stroke mengalami penurunankognitif dan motorik yang menyebabkan keterbatasan padapenderitanya dalam melakukan aktivitas sehingga keluargamemegang peranan penting pada kondisi penderita stroke.Penelitian ini bertujuan untuk mengetahui hubungan tingkatpendidikan dengan resiliensi keluarga penderita stroke iskemikserangan pertama. Penelitian ini adalah studi kuantitatif dengandesain penelitian cross-sectional yang menggunakan data primerpada bulan Januari-Februari 2022 di poli rawat inap RumahSakit Otak Dr. Drs. M. Hatta Bukittinggi (RSOMH). Sampelpenelitian adalah keluarga dan penderita stroke iskemik di RSOMHyang berjumlah 229 orang berdasarkan kriteria inklusi.Pengumpulan data menggunakan instrumen resiliensi keluarga(RESILIENSI-GA). Analisis data menggunakan analisis un...

Jurnal Epidemiologi Kesehatan Indonesia

Data terkait karakteristik epidemiologi COVID-19 di Indonesia masih langka. Penelitian ini bertuj... more Data terkait karakteristik epidemiologi COVID-19 di Indonesia masih langka. Penelitian ini bertujuan untuk menggambarkan epidemiologi COVID-19 berdasarkan dimensi orang, tempat dan waktu. Hasil penelitian ini diharapkan dapat digunakan sebagai dasar upaya intervensi yang lebih optimal dan tepat sasaran. Penelitian cross sectional ini memasukkan seluruh kasus konfirmasi COVID-19 dari sepuluh Kabupaten dan dua Kotamadya di Provinsi Riau dari tanggal 18 Maret 2020 hingga 9 Oktober 2021. Kami menggunakan analisis univariat dan bivariat untuk mendeskripsikan karakteristik epidemiologi COVID-19. Hasil penelitian ini menunjukkan bahwa dari 122.497 kasus COVID-19, 51,3% kasus adalah perempuan. Median umur 35 tahun (IQR: 24 - 49 tahun), 52,1% kasus kelompok umur 26 hingga 51 tahun, 0,4% kasus re-infeksi COVID-19, 3,3% kasus meninggal, 87,3% kasus dengan isolasi mandiri/ fasilitas khusus, dan 70,5% tempat tinggal kasus di wilayah daratan. Waktu sakit tertinggi atau puncak gelombang COVID-19 p...

The 1st ICGH International Conference on Global Health, 2017

Information given in this MICRODIS Working Paper Series reflects the authors' views only. The Com... more Information given in this MICRODIS Working Paper Series reflects the authors' views only. The Community is not liable for any use that may be made of the information contained therein.

The Indonesian Journal of Infectious Diseases, 2017

AbstrakLatar Belakang : Human Immunodeficiency Virus (HIV) merupakan jenis retrovirus yang mengin... more AbstrakLatar Belakang : Human Immunodeficiency Virus (HIV) merupakan jenis retrovirus yang menginfeksi sistem kekebalan tubuh manusia yang menyebabkan Acquired Immunodefiency Syndrome (AIDS),. Kehadiran kuman TB menyebabkan progresivitas kasus ko-infeksi TB-HIV bertambah buruk sehingga mengancam jiwa penderitanya. Penelitian ini bertujuan untuk mengetahui gambaran kesintasan satu tahun pasien ko-infeksi TB-HIV berdasarkan waktu awal pengobatan ARV.Metode : Penelitian ini menggunakan desain kohort retrospektif di RSPI Prof. Dr. Sulianti Saroso tahun 2013-2015. Sumber data yang digunakan berasal dari penelusuran pada register pra ARV dan ARV, Form TB 01, buku monitoring ARV, monitoring farmasi ARV, pelacakan ikhtisar ARV dan status rekam medis. Pengumpulan data melibatkan petugas Pokja HIV/AIDS dan dokter (validasi diagnosa dan kovariat) yang di blind atas hipotesis penelitian.Hasil : Probabilitas ketahanan hidup kumulatif satu tahun pasien ko-infeksi TB-HIV yang mendapatkan awal peng...

Latar belakang: Kematian neonatal dini merupakan penyumbang kematian bayi dan perinatal yang meru... more Latar belakang: Kematian neonatal dini merupakan penyumbang kematian bayi dan perinatal yang merupakan indikator derajat kesejahteraan dan kesehatan bangsa. Angka kematian bayi dan perinatal di Indonesia masih tergolong tinggi dibanding negara Asia lainnya. Komplikasi kehamilan diduga menjadi faktor kuat kematian neonatal dini. Penelitian bertujuan untuk mengetahui seberapa besar pengaruh adanya komplikasi kehamilan dan setiap jenis komplikasi kehamilan serta ingin mengetahui PAR (Population Attributle Risk) terhadap kematian neonatal dini di Indonesia pada anak yang lahir 2002–2007 terhadap kematian neonatal dini setelah dikendalikan seluruh confounding . Metode: Desain studi yang digunakan dalam penelitian ini adalah crossectional dengan analisis multivariat complex sample cox regression . Sampel penelitiansebanyak 13893 dari 33 provinsi Indonesia yang diambil dengan metode Stratified two-stage cluster design . Hasil: Hasil analisis menunjukkan komplikasi kehamilan terhadap kemati...

Proceedings of the 4th International Symposium on Health Research (ISHR 2019), 2020

Globally premature death due to cardiovascular disease and stroke continues increase, predicted m... more Globally premature death due to cardiovascular disease and stroke continues increase, predicted many UN member countries cannot reach target of reducing premature death by 25% by 2025. Similar in Indonesia prevalence of stroke increased from 8.3 to 12.1 per mile population (Riskesdas,2007-2013), the proportion of deaths correlated with an increase of prevalence 15.84%, growing 4.39% in 2013 (IHME, 2007-2013). These situation in line with increasing prevalence of teenage smokers. Risk assessment (PAR) analysis using Riskesdas 2013 was carried out to finding out its impact on the incidence stroke, if exposure smoking was eliminated. We used 7859 stroke cases, 50.3% was men. Bivariate analysis to determine features of stroke risk factors (p <0.001), we do multivariate analysis to obtain the prevalence rate and risk factor intervention models. Interventions on risk factors of tobacco consumption or hypertension are predicted to have an opportunity reduce incidence of stroke by 68% with PR 9.55. The target of reducing 100% of tobacco consumption predicted reduce 3031 cases of stroke, while reducing 40% of hypertension reduce 1212.Behavioural modification with a healthy lifestyle, stop tobacco consumption and preventing increase in novice smokers, are the main targets of the tobacco control intervention program in the community.

Riset Informasi Kesehatan, 2019

Background: Pneumonia is more commonly among children under five years old and caused by several ... more Background: Pneumonia is more commonly among children under five years old and caused by several risk factors. Pneumonia causes 1.9 – 2.2 million children death worldwide every year, in which 1.3 million (81%) generally occurs in first 2 years of life. Seventy two percent of pneumonia occurs in children under five years old in 15 countries. Indonesia was the 7th highest in the world. The prevalence of pneumonia in Indonesia was 18.5/1000 population and only 1.6/1000 received treatment. This study aim to elaborate the risk factors of the influenza related pneumonia in children under five years old. Method: The pneumonia control program in Ministry of Health focuses on early detection and treatment for bacterial pneumonia in community. Severe acute respiratory infection (SARI) can develop fatal pneumonia. We collected data from the pneumonia surveillance database in the Acute Respiratory Infection subdirectorate. Results: Influenza related pneumonia was 13% of acute lower respiratory...

Kesmas: Jurnal Kesehatan Masyarakat Nasional, 2022

The Indonesian Government established a social distancing policy to prevent COVID-19 transmission... more The Indonesian Government established a social distancing policy to prevent COVID-19 transmission. However, this implementation will be ineffective without the compliance of the people. This research aimed to analyze the relationship between public perception and obedience with social distancing in terms of the variables based on the Health Belief Model. This study used a cross-sectional design with a population of DKI Jakarta’s indigenes within the productive age of 15-64 years. The sample comprised 408 participants, with the independent variables of socio-demographics (age, gender, occupation, and education) and health beliefs (perceived susceptibility, severity, benefits, barriers, and self-efficacy). Meanwhile, obedience to social distancing was the dependent variable. Data were obtained through an online questionnaire and evaluated with the bivariate and multivariate analysis using Chi-square and logistic regression tests. Gender (OR=2.327; 95% CI=1.404-3.857) and perceived sel...

Indian Journal of Public Health Research & Development

Open Access Macedonian Journal of Medical Sciences

BACKGROUND: Malaria is an infectious disease caused by Plasmodium sp. This disease often occurs i... more BACKGROUND: Malaria is an infectious disease caused by Plasmodium sp. This disease often occurs in tropical countries and has sometimes been reported in agricultural countries. This vector-borne disease is associated with environmental factors and the presence of vectors. Some studies found that Anopheles is resistant to insecticide, and this topic was encouraged by the WHO for malaria control. AIM: This research aimed to explain the causal effects of agricultural pesticide exposure on malaria incidence and Anopheles susceptibility in an endemic area of Indonesia. METHODS: A case–control study was conducted between September and October 2016 in Purworejo, Central Java. The case group involved 131 individuals who had malaria in 2016 based on their medical records, whereas the control group comprised 131 individuals who were neighbors of the cases and never had a history of malaria. Cases were selected randomly from hospital medical records. Both case and control groups were interview...

Kesmas: National Public Health Journal

The World Health Organization estimated that chronic obstructive pulmonary disease (COPD) will be... more The World Health Organization estimated that chronic obstructive pulmonary disease (COPD) will be the highest non-communicable disease worldwide by2030, and pesticide exposure is one of major risk factors. This study aimed to determine effect of pesticide exposure on lung dysfunction among paddyfarmers. A case-control study was performed on April - May 2016 in Purworejo. The case group comprised 66 farmers suffering from lung dysfunction during2015 based on medical records, while the control group comprised 59 neighboring farmers showing normal lung function. Both case and control groups weretested using a spirometer and COPD assessment test (CAT) questionnaire. Logistic regression analysis of pesticide quantity (OR = 0.75; 95% CI = 0.317 -1.754) and duration of spraying (OR = 1.11; 95% CI = 0.430 - 2.891) adjusted for confounders showed no clear associations. Pesticide remained a potentialhealth risk for lung dysfunction due to farming duration (OR = 5.61; 95% CI = 1.124 - 27.990) ...

Kesmas: National Public Health Journal

Agriculture is one of major sectors of Indonesia economic source with the high volume of pesticid... more Agriculture is one of major sectors of Indonesia economic source with the high volume of pesticide used. Unfortunately, adverse health effect of neurotoxic pesticide has never been reported in Indonesia. This study aimed to determine effectiveness of personal protective equipment (PPE) during the use of pesticides to neurological symptoms in farmers. This study was cross-sectionally conducted from April to May 2016 in Purworejo District. About 125 farmers were selected using purposive sampling, and restriction was applied in male farmers due to the high proportion of male sprayer. Data was collected by observation and interview. Logistic regression showed protective result of PPE used during preparing (POR = 0.40; 95% CI= 0.11-1.42) and spraying (POR = 0.38; 95% CI = 0.11-1.32), also following wind direction (POR = 0.88; 95% CI = 0.27-2.87) and bathing after spraying (POR = 0.33; 95% CI = 0.04-3.01) after controlled by confounders. Proper PPE used during preparing and spraying pesticide, following wind direction during spraying, and bathing after spraying can decrease risk of neurological symptoms because of pesticide exposure.

Journal of Epidemiology and Global Health

Background: The HIV epidemic remains a public health problem with rising tuberculosis (TB) number... more Background: The HIV epidemic remains a public health problem with rising tuberculosis (TB) numbers around the world. Antiretroviral (ARV) therapy (ART) is essential to increase the survival of patients with TB-HIV coinfection. The aim of this study is to investigate the effect of ARV treatment initiation within TB treatment duration for the survival of patients with TB-HIV coinfection. Methods: This is a retrospective cohort study of patients with TB-HIV coinfection and who were ARV naive from Prof. Dr. Sulianti Saroso Infectious Disease Hospital between January 2011 and May 2014 (N = 275). The Kaplan-Meier method, bivariate with the log rank test, and multivariate with the Cox regression were applied in this study. Results: Cumulative survival probability of the patients with TB-HIV coinfection receiving ARV in a year was 81.5%. The death rate in patients with TB-HIV coinfection who received late ART initiation during TB treatment is higher by 2.4 times [adjusted hazard ratio (aHR) = 2.4, 95% confidence interval: 1.3-4.5, p = 0.006] compared with the patients who were in early ART initiation and were thereafter adjusted by the location of Mycobacterium tuberculosis infection. Conclusion: The effect of ART initiation is essential in the intensive phase (2-8 weeks) of anti-TB medication to increase the survival among TB-HIV coinfection group.

JURNAL ILMIAH KESEHATAN MASYARAKAT : Media Komunikasi Komunitas Kesehatan Masyarakat

Latar Belakang: Kebakaran hutan yang terjadi di Provinsi Bengkulu tahun 2015 menyebabkan adanya p... more Latar Belakang: Kebakaran hutan yang terjadi di Provinsi Bengkulu tahun 2015 menyebabkan adanya pencemaran udara baik di dalam maupun di luar ruangan. Hal ini juga mengakibatkan meningkatnya kejadian ISPA pada balita. Tujuan penelitian ini adalah untuk mengetahui determinan kejadian ISPA pada balita di Kota Bengkulu saat kebakaran hutan tahun 2015. Metode: Metode penelitian yang digunakan adalah case control. Kasus merupakan balita yang berkunjung ke Puskesmas Kecamatan dan didiagnosa menderita ISPA dan kontrol adalah dua balita tetangga kasus yang ditemui pertama kali. Hasil: Hasil analisis menunjukkan bahwa jenis atap (OR: 2,79; 95% CI: 1,36-5,69), ventilasi (OR: 2,60; 95% CI: 1,39-4,84), kepadatan hunian (OR: 2,14; 95% CI: 1,07-4,28), dan asap bahan bakar memasak (OR: 4,14; 95% CI: 1,56-10,9) memiliki hubungan yang kuat terhadap ISPA. Kesimpulan: Jadi, ada hubungan antara kondisi fisik rumah, kepadatan hunian dan pajanan asap terhadap kejadian ISPA pada Balita setelah dikontrol...

Jurnal Epidemiologi Kesehatan Indonesia

Penyakit stroke menjadi salah satu penyebab kematian tertinggidan merupakan penyumbang ketiga kec... more Penyakit stroke menjadi salah satu penyebab kematian tertinggidan merupakan penyumbang ketiga kecacatan secara global.Jenis stroke yang paling umum terjadi di Indonesia adalah strokeiskemik. Sebagian besar penderita stroke mengalami penurunankognitif dan motorik yang menyebabkan keterbatasan padapenderitanya dalam melakukan aktivitas sehingga keluargamemegang peranan penting pada kondisi penderita stroke.Penelitian ini bertujuan untuk mengetahui hubungan tingkatpendidikan dengan resiliensi keluarga penderita stroke iskemikserangan pertama. Penelitian ini adalah studi kuantitatif dengandesain penelitian cross-sectional yang menggunakan data primerpada bulan Januari-Februari 2022 di poli rawat inap RumahSakit Otak Dr. Drs. M. Hatta Bukittinggi (RSOMH). Sampelpenelitian adalah keluarga dan penderita stroke iskemik di RSOMHyang berjumlah 229 orang berdasarkan kriteria inklusi.Pengumpulan data menggunakan instrumen resiliensi keluarga(RESILIENSI-GA). Analisis data menggunakan analisis un...

Jurnal Epidemiologi Kesehatan Indonesia

Data terkait karakteristik epidemiologi COVID-19 di Indonesia masih langka. Penelitian ini bertuj... more Data terkait karakteristik epidemiologi COVID-19 di Indonesia masih langka. Penelitian ini bertujuan untuk menggambarkan epidemiologi COVID-19 berdasarkan dimensi orang, tempat dan waktu. Hasil penelitian ini diharapkan dapat digunakan sebagai dasar upaya intervensi yang lebih optimal dan tepat sasaran. Penelitian cross sectional ini memasukkan seluruh kasus konfirmasi COVID-19 dari sepuluh Kabupaten dan dua Kotamadya di Provinsi Riau dari tanggal 18 Maret 2020 hingga 9 Oktober 2021. Kami menggunakan analisis univariat dan bivariat untuk mendeskripsikan karakteristik epidemiologi COVID-19. Hasil penelitian ini menunjukkan bahwa dari 122.497 kasus COVID-19, 51,3% kasus adalah perempuan. Median umur 35 tahun (IQR: 24 - 49 tahun), 52,1% kasus kelompok umur 26 hingga 51 tahun, 0,4% kasus re-infeksi COVID-19, 3,3% kasus meninggal, 87,3% kasus dengan isolasi mandiri/ fasilitas khusus, dan 70,5% tempat tinggal kasus di wilayah daratan. Waktu sakit tertinggi atau puncak gelombang COVID-19 p...

The 1st ICGH International Conference on Global Health, 2017

Information given in this MICRODIS Working Paper Series reflects the authors' views only. The Com... more Information given in this MICRODIS Working Paper Series reflects the authors' views only. The Community is not liable for any use that may be made of the information contained therein.

The Indonesian Journal of Infectious Diseases, 2017

AbstrakLatar Belakang : Human Immunodeficiency Virus (HIV) merupakan jenis retrovirus yang mengin... more AbstrakLatar Belakang : Human Immunodeficiency Virus (HIV) merupakan jenis retrovirus yang menginfeksi sistem kekebalan tubuh manusia yang menyebabkan Acquired Immunodefiency Syndrome (AIDS),. Kehadiran kuman TB menyebabkan progresivitas kasus ko-infeksi TB-HIV bertambah buruk sehingga mengancam jiwa penderitanya. Penelitian ini bertujuan untuk mengetahui gambaran kesintasan satu tahun pasien ko-infeksi TB-HIV berdasarkan waktu awal pengobatan ARV.Metode : Penelitian ini menggunakan desain kohort retrospektif di RSPI Prof. Dr. Sulianti Saroso tahun 2013-2015. Sumber data yang digunakan berasal dari penelusuran pada register pra ARV dan ARV, Form TB 01, buku monitoring ARV, monitoring farmasi ARV, pelacakan ikhtisar ARV dan status rekam medis. Pengumpulan data melibatkan petugas Pokja HIV/AIDS dan dokter (validasi diagnosa dan kovariat) yang di blind atas hipotesis penelitian.Hasil : Probabilitas ketahanan hidup kumulatif satu tahun pasien ko-infeksi TB-HIV yang mendapatkan awal peng...

Latar belakang: Kematian neonatal dini merupakan penyumbang kematian bayi dan perinatal yang meru... more Latar belakang: Kematian neonatal dini merupakan penyumbang kematian bayi dan perinatal yang merupakan indikator derajat kesejahteraan dan kesehatan bangsa. Angka kematian bayi dan perinatal di Indonesia masih tergolong tinggi dibanding negara Asia lainnya. Komplikasi kehamilan diduga menjadi faktor kuat kematian neonatal dini. Penelitian bertujuan untuk mengetahui seberapa besar pengaruh adanya komplikasi kehamilan dan setiap jenis komplikasi kehamilan serta ingin mengetahui PAR (Population Attributle Risk) terhadap kematian neonatal dini di Indonesia pada anak yang lahir 2002–2007 terhadap kematian neonatal dini setelah dikendalikan seluruh confounding . Metode: Desain studi yang digunakan dalam penelitian ini adalah crossectional dengan analisis multivariat complex sample cox regression . Sampel penelitiansebanyak 13893 dari 33 provinsi Indonesia yang diambil dengan metode Stratified two-stage cluster design . Hasil: Hasil analisis menunjukkan komplikasi kehamilan terhadap kemati...

Proceedings of the 4th International Symposium on Health Research (ISHR 2019), 2020

Globally premature death due to cardiovascular disease and stroke continues increase, predicted m... more Globally premature death due to cardiovascular disease and stroke continues increase, predicted many UN member countries cannot reach target of reducing premature death by 25% by 2025. Similar in Indonesia prevalence of stroke increased from 8.3 to 12.1 per mile population (Riskesdas,2007-2013), the proportion of deaths correlated with an increase of prevalence 15.84%, growing 4.39% in 2013 (IHME, 2007-2013). These situation in line with increasing prevalence of teenage smokers. Risk assessment (PAR) analysis using Riskesdas 2013 was carried out to finding out its impact on the incidence stroke, if exposure smoking was eliminated. We used 7859 stroke cases, 50.3% was men. Bivariate analysis to determine features of stroke risk factors (p <0.001), we do multivariate analysis to obtain the prevalence rate and risk factor intervention models. Interventions on risk factors of tobacco consumption or hypertension are predicted to have an opportunity reduce incidence of stroke by 68% with PR 9.55. The target of reducing 100% of tobacco consumption predicted reduce 3031 cases of stroke, while reducing 40% of hypertension reduce 1212.Behavioural modification with a healthy lifestyle, stop tobacco consumption and preventing increase in novice smokers, are the main targets of the tobacco control intervention program in the community.

Riset Informasi Kesehatan, 2019

Background: Pneumonia is more commonly among children under five years old and caused by several ... more Background: Pneumonia is more commonly among children under five years old and caused by several risk factors. Pneumonia causes 1.9 – 2.2 million children death worldwide every year, in which 1.3 million (81%) generally occurs in first 2 years of life. Seventy two percent of pneumonia occurs in children under five years old in 15 countries. Indonesia was the 7th highest in the world. The prevalence of pneumonia in Indonesia was 18.5/1000 population and only 1.6/1000 received treatment. This study aim to elaborate the risk factors of the influenza related pneumonia in children under five years old. Method: The pneumonia control program in Ministry of Health focuses on early detection and treatment for bacterial pneumonia in community. Severe acute respiratory infection (SARI) can develop fatal pneumonia. We collected data from the pneumonia surveillance database in the Acute Respiratory Infection subdirectorate. Results: Influenza related pneumonia was 13% of acute lower respiratory...

Kesmas: Jurnal Kesehatan Masyarakat Nasional, 2022

The Indonesian Government established a social distancing policy to prevent COVID-19 transmission... more The Indonesian Government established a social distancing policy to prevent COVID-19 transmission. However, this implementation will be ineffective without the compliance of the people. This research aimed to analyze the relationship between public perception and obedience with social distancing in terms of the variables based on the Health Belief Model. This study used a cross-sectional design with a population of DKI Jakarta’s indigenes within the productive age of 15-64 years. The sample comprised 408 participants, with the independent variables of socio-demographics (age, gender, occupation, and education) and health beliefs (perceived susceptibility, severity, benefits, barriers, and self-efficacy). Meanwhile, obedience to social distancing was the dependent variable. Data were obtained through an online questionnaire and evaluated with the bivariate and multivariate analysis using Chi-square and logistic regression tests. Gender (OR=2.327; 95% CI=1.404-3.857) and perceived sel...

Indian Journal of Public Health Research & Development

Open Access Macedonian Journal of Medical Sciences

BACKGROUND: Malaria is an infectious disease caused by Plasmodium sp. This disease often occurs i... more BACKGROUND: Malaria is an infectious disease caused by Plasmodium sp. This disease often occurs in tropical countries and has sometimes been reported in agricultural countries. This vector-borne disease is associated with environmental factors and the presence of vectors. Some studies found that Anopheles is resistant to insecticide, and this topic was encouraged by the WHO for malaria control. AIM: This research aimed to explain the causal effects of agricultural pesticide exposure on malaria incidence and Anopheles susceptibility in an endemic area of Indonesia. METHODS: A case–control study was conducted between September and October 2016 in Purworejo, Central Java. The case group involved 131 individuals who had malaria in 2016 based on their medical records, whereas the control group comprised 131 individuals who were neighbors of the cases and never had a history of malaria. Cases were selected randomly from hospital medical records. Both case and control groups were interview...

Kesmas: National Public Health Journal

The World Health Organization estimated that chronic obstructive pulmonary disease (COPD) will be... more The World Health Organization estimated that chronic obstructive pulmonary disease (COPD) will be the highest non-communicable disease worldwide by2030, and pesticide exposure is one of major risk factors. This study aimed to determine effect of pesticide exposure on lung dysfunction among paddyfarmers. A case-control study was performed on April - May 2016 in Purworejo. The case group comprised 66 farmers suffering from lung dysfunction during2015 based on medical records, while the control group comprised 59 neighboring farmers showing normal lung function. Both case and control groups weretested using a spirometer and COPD assessment test (CAT) questionnaire. Logistic regression analysis of pesticide quantity (OR = 0.75; 95% CI = 0.317 -1.754) and duration of spraying (OR = 1.11; 95% CI = 0.430 - 2.891) adjusted for confounders showed no clear associations. Pesticide remained a potentialhealth risk for lung dysfunction due to farming duration (OR = 5.61; 95% CI = 1.124 - 27.990) ...

Kesmas: National Public Health Journal

Agriculture is one of major sectors of Indonesia economic source with the high volume of pesticid... more Agriculture is one of major sectors of Indonesia economic source with the high volume of pesticide used. Unfortunately, adverse health effect of neurotoxic pesticide has never been reported in Indonesia. This study aimed to determine effectiveness of personal protective equipment (PPE) during the use of pesticides to neurological symptoms in farmers. This study was cross-sectionally conducted from April to May 2016 in Purworejo District. About 125 farmers were selected using purposive sampling, and restriction was applied in male farmers due to the high proportion of male sprayer. Data was collected by observation and interview. Logistic regression showed protective result of PPE used during preparing (POR = 0.40; 95% CI= 0.11-1.42) and spraying (POR = 0.38; 95% CI = 0.11-1.32), also following wind direction (POR = 0.88; 95% CI = 0.27-2.87) and bathing after spraying (POR = 0.33; 95% CI = 0.04-3.01) after controlled by confounders. Proper PPE used during preparing and spraying pesticide, following wind direction during spraying, and bathing after spraying can decrease risk of neurological symptoms because of pesticide exposure.

Journal of Epidemiology and Global Health

Background: The HIV epidemic remains a public health problem with rising tuberculosis (TB) number... more Background: The HIV epidemic remains a public health problem with rising tuberculosis (TB) numbers around the world. Antiretroviral (ARV) therapy (ART) is essential to increase the survival of patients with TB-HIV coinfection. The aim of this study is to investigate the effect of ARV treatment initiation within TB treatment duration for the survival of patients with TB-HIV coinfection. Methods: This is a retrospective cohort study of patients with TB-HIV coinfection and who were ARV naive from Prof. Dr. Sulianti Saroso Infectious Disease Hospital between January 2011 and May 2014 (N = 275). The Kaplan-Meier method, bivariate with the log rank test, and multivariate with the Cox regression were applied in this study. Results: Cumulative survival probability of the patients with TB-HIV coinfection receiving ARV in a year was 81.5%. The death rate in patients with TB-HIV coinfection who received late ART initiation during TB treatment is higher by 2.4 times [adjusted hazard ratio (aHR) = 2.4, 95% confidence interval: 1.3-4.5, p = 0.006] compared with the patients who were in early ART initiation and were thereafter adjusted by the location of Mycobacterium tuberculosis infection. Conclusion: The effect of ART initiation is essential in the intensive phase (2-8 weeks) of anti-TB medication to increase the survival among TB-HIV coinfection group.