Rebecca McConnico - Academia.edu (original) (raw)

Papers by Rebecca McConnico

PCR (Polymer Chain Reaction) of tracheal wash fluid is more sensitive than culture techniques (fe... more PCR (Polymer Chain Reaction) of tracheal wash fluid is more sensitive than culture techniques (fewer false-negative results) for diagnosis of R. equi pneumonia and results are available more rapidly. Culture should be performed at the same time as PCR to identify other potential pathogens. Authors’ addresses: Department of Veterinary Clinical Sciences (Sellon) and Microbiology and Pathology (Besser), College of Veterinary Medicine, Washington State University, Pullman, WA 99164; Department of Veterinary Clinical Sciences, School of Veterinary Medicine, Louisiana State University, Baton Rouge, LA 70803 (McConnico); and Department of Clinical Sciences, 4700 Hillsborough St., College of Veterinary Medicine, North Carolina State University, Raleigh, NC 27606 (Vivrette). © 2000 AAEP.

Veterinary Clinics of North America: Food Animal Practice, 2018

Keeping people and animals out of harm's way, preventing property loss, and working together in t... more Keeping people and animals out of harm's way, preventing property loss, and working together in the community with animal health officials, other animal agriculture stakeholders and officials are important in building community resilience during disasters. Developing plans for neighbors helping each other evacuate animals is important. Producer helping producer, veterinarian helping veterinarian, and community helping community build resilience by preventing loss, responding to needs, and recovering and restoring livelihoods.

Prehospital and Disaster Medicine, 2017

Journal of Equine Veterinary Science, 2016

Open Veterinary Journal, 2016

Integrative veterinary medicine (IVM) describes the combination of complementary and alternative ... more Integrative veterinary medicine (IVM) describes the combination of complementary and alternative therapies with conventional care and is guided by the best available evidence. Veterinarians frequently encounter questions about complementary and alternative veterinary medicine (CAVM) in practice, and the general public has demonstrated increased interest in these areas for both human and animal health. Consequently, veterinary students should receive adequate exposure to the principles, theories, and current knowledge supporting or refuting such techniques. A proposed curriculum guideline would broadly introduce students to the objective evaluation of new veterinary treatments while increasing their preparation for responding to questions about IVM in clinical practice. Such a course should be evidence-based, unbiased, and unaffiliated with any particular CAVM advocacy or training group. All IVM courses require routine updating as new information becomes available. Controversies regarding IVM and CAVM must be addressed within the course and throughout the entire curriculum. Instructional honesty regarding the uncertainties in this emerging field is critical. Increased training of future veterinary professionals in IVM may produce an openness to new ideas that characterizes the scientific method and a willingness to pursue and incorporate evidence-based

Equine Veterinary Education, 2015

This case series describes 3 horses rescued from flooded areas, hospitalised and treated at the L... more This case series describes 3 horses rescued from flooded areas, hospitalised and treated at the Louisiana State University Veterinary Teaching Hospital in the wake of Hurricane Isaac. The purpose of the paper is to familiarise practitioners with the injuries that may be found in flood-afflicted horses and livestock. Case 1 presented with a degloving injury of the right hindlimb. The gelding developed neurological signs and was subjected to euthanasia; necropsy was consistent with Salmonella sepsis and disseminated mycosis due to Candida krusei, the first case reported in a horse. Case 2 presented with dermatitis attributable to chemical exposure and pneumonia and was subjected to euthanasia due to severe bilateral laminitis. Case 3 sustained a degloving injury of the left hindlimb and was subjected to euthanasia due to intractable pain. This case series illustrates the need for preparation and evacuation to avoid life-threatening injuries in equids and livestock caused by hurricanes and their aftermath.

Canadian journal of veterinary research = Revue canadienne de recherche vétérinaire, 2002

The objective of this project was to determine early tissue biochemical events associated with in... more The objective of this project was to determine early tissue biochemical events associated with increased colonic secretion during the acute stage of castor-oil-induced colitis by measuring cecal mucosal and submucosal malondialdehyde (MDA) and prostaglandin E2 (PGE2), levels in ponies. Intestinal tissue (inflamed or healthy) samples were obtained from 4 age- and sex-matched Shetland ponies. Biochemical methods were used to determine MDA and PGE2 levels in intestinal tissue samples from inflamed and healthy equine intestine. Inflamed tissue MDA and PGE2 levels increased with time after castor oil challenge and correlated with granulocyte infiltration, as determined by myeloperoxidase levels in a companion study. Elevated intestinal tissue MDA levels suggest that lipid peroxidation could be attributed to reactive oxygen metabolites (ROM) released from stimulated, recruited, and resident granulocytes. Tissue levels of MDA and PGE2 suggest a role for granulocyte-derived mediators of int...

Journal of the American Veterinary Medical Association, 1997

Increased popularity during the past decade of brodifacoum, an anticoagulant rodenticide, has led... more Increased popularity during the past decade of brodifacoum, an anticoagulant rodenticide, has led to an increase in cases of accidental poisoning in nontarget species, including pets and farm animals. Pharmacokinetics of second-generation anticoagulant rodenticides such as brodifacoum are substantially different from those of first-generation anticoagulant rodenticides such as warfarin. This difference dramatically influences management of exposure in terms of duration and cost of treatment and may affect outcome. The National Poison Control Center reports that approximately 50 cases of brodifacoum exposure have occurred in horses between 1993 and 1997. To our knowledge, this report is the first complete clinical description of accidental ingestion of a potentially lethal dose of brodifacoum in horses. Early recognition of exposure to brodifacoum, subsequent treatment with adequate doses of vitamin K1, and sequential monitoring of clotting times and serum brodifacoum concentration p...

Journal of the American Veterinary Medical Association, Jan 15, 1989

The Cornell veterinarian, 1992

Two horses with red maple (Acer rubrum) toxicity responded to treatment with high doses of vitami... more Two horses with red maple (Acer rubrum) toxicity responded to treatment with high doses of vitamin C (ascorbic acid), in addition to blood transfusions, and intravenous fluid therapy. The clinical course included Heinz body anemia, marked methemoglobinemia, depression, and evidence of severe tissue anoxia. Clinical recovery was dramatic with stabilization achieved 36 hours following the initiation of ascorbic acid therapy.

Journal of the American Veterinary Medical Association, 1992

A 5-year-old female American Quarter Horse was determined to have immune-mediated hemolytic anemi... more A 5-year-old female American Quarter Horse was determined to have immune-mediated hemolytic anemia after detection of a positive response to a direct Coombs' test. Penicillin-induced immune-mediated hemolytic anemia was confirmed via a direct antiglobulin test, using penicillin-coated RBC. The horse was clinically improved and the anemia resolved in response to supportive care and discontinuation of penicillin treatment. Penicillin should be considered a possible cause of immune-mediated hemolytic anemia in horses.

Equine Veterinary Education, 2009

Equine Veterinary Education, 2010

Equine Veterinary Education, 2010

This article evaluates the European Union (EU)'s border strategy for the Western Balkans. It iden... more This article evaluates the European Union (EU)'s border strategy for the Western Balkans. It identifies an increasing tension between, on the one hand, the Union's use of its border strategy to foster the long-term stabilisation of the countries of the Western Balkans and their future integration into the EU and, on the other hand, the use of border management as an instrument to ensure its own internal security. This tension can be broken down into a threefold contradiction inbuilt into the EU's strategy: short-term vs. long-term objectives; a security vs. development focus; and interventionism vs. local ownership approaches. These contradictions, aggravated by local and regional political, economic and security challenges, can explain existing shortcomings in the EU's border interventions in the Western Balkans.

Equine Veterinary Education, 2010

Equine Veterinary Education, 2010

Robinson's Current Therapy in Equine Medicine, 2015

Robinson's Current Therapy in Equine Medicine, 2015

Veterinary Clinics of North America: Equine Practice, 2007

Journal of Veterinary Internal Medicine, 1997

Persistent hyperammonemia was diagnosed in 2 Morgan fillies with clinical signs that developed ea... more Persistent hyperammonemia was diagnosed in 2 Morgan fillies with clinical signs that developed early in the postweaning period. Diagnostic evaluation, including routine serum chemistries, CBC, liver biopsy, hepatic ultrasonography, liver function test, and necropsy findings did not support a toxic, developmental, or infectious cause. Abnormal serum amino acid and urine orotic acid concentrations suggest that the foals may have had an inherited disorders described in humans as hyperornithinemia, hyperammonemia, and homocitrullinuria (HHH) syndrome. The disorder is thought to be caused by a defective mitochondrial transporter protein, such that ornithine, required for complete urea synthesis, is deficient, thus causing increases in blood ammonia and ornithine concentrations.

PCR (Polymer Chain Reaction) of tracheal wash fluid is more sensitive than culture techniques (fe... more PCR (Polymer Chain Reaction) of tracheal wash fluid is more sensitive than culture techniques (fewer false-negative results) for diagnosis of R. equi pneumonia and results are available more rapidly. Culture should be performed at the same time as PCR to identify other potential pathogens. Authors’ addresses: Department of Veterinary Clinical Sciences (Sellon) and Microbiology and Pathology (Besser), College of Veterinary Medicine, Washington State University, Pullman, WA 99164; Department of Veterinary Clinical Sciences, School of Veterinary Medicine, Louisiana State University, Baton Rouge, LA 70803 (McConnico); and Department of Clinical Sciences, 4700 Hillsborough St., College of Veterinary Medicine, North Carolina State University, Raleigh, NC 27606 (Vivrette). © 2000 AAEP.

Veterinary Clinics of North America: Food Animal Practice, 2018

Keeping people and animals out of harm's way, preventing property loss, and working together in t... more Keeping people and animals out of harm's way, preventing property loss, and working together in the community with animal health officials, other animal agriculture stakeholders and officials are important in building community resilience during disasters. Developing plans for neighbors helping each other evacuate animals is important. Producer helping producer, veterinarian helping veterinarian, and community helping community build resilience by preventing loss, responding to needs, and recovering and restoring livelihoods.

Prehospital and Disaster Medicine, 2017

Journal of Equine Veterinary Science, 2016

Open Veterinary Journal, 2016

Integrative veterinary medicine (IVM) describes the combination of complementary and alternative ... more Integrative veterinary medicine (IVM) describes the combination of complementary and alternative therapies with conventional care and is guided by the best available evidence. Veterinarians frequently encounter questions about complementary and alternative veterinary medicine (CAVM) in practice, and the general public has demonstrated increased interest in these areas for both human and animal health. Consequently, veterinary students should receive adequate exposure to the principles, theories, and current knowledge supporting or refuting such techniques. A proposed curriculum guideline would broadly introduce students to the objective evaluation of new veterinary treatments while increasing their preparation for responding to questions about IVM in clinical practice. Such a course should be evidence-based, unbiased, and unaffiliated with any particular CAVM advocacy or training group. All IVM courses require routine updating as new information becomes available. Controversies regarding IVM and CAVM must be addressed within the course and throughout the entire curriculum. Instructional honesty regarding the uncertainties in this emerging field is critical. Increased training of future veterinary professionals in IVM may produce an openness to new ideas that characterizes the scientific method and a willingness to pursue and incorporate evidence-based

Equine Veterinary Education, 2015

This case series describes 3 horses rescued from flooded areas, hospitalised and treated at the L... more This case series describes 3 horses rescued from flooded areas, hospitalised and treated at the Louisiana State University Veterinary Teaching Hospital in the wake of Hurricane Isaac. The purpose of the paper is to familiarise practitioners with the injuries that may be found in flood-afflicted horses and livestock. Case 1 presented with a degloving injury of the right hindlimb. The gelding developed neurological signs and was subjected to euthanasia; necropsy was consistent with Salmonella sepsis and disseminated mycosis due to Candida krusei, the first case reported in a horse. Case 2 presented with dermatitis attributable to chemical exposure and pneumonia and was subjected to euthanasia due to severe bilateral laminitis. Case 3 sustained a degloving injury of the left hindlimb and was subjected to euthanasia due to intractable pain. This case series illustrates the need for preparation and evacuation to avoid life-threatening injuries in equids and livestock caused by hurricanes and their aftermath.

Canadian journal of veterinary research = Revue canadienne de recherche vétérinaire, 2002

The objective of this project was to determine early tissue biochemical events associated with in... more The objective of this project was to determine early tissue biochemical events associated with increased colonic secretion during the acute stage of castor-oil-induced colitis by measuring cecal mucosal and submucosal malondialdehyde (MDA) and prostaglandin E2 (PGE2), levels in ponies. Intestinal tissue (inflamed or healthy) samples were obtained from 4 age- and sex-matched Shetland ponies. Biochemical methods were used to determine MDA and PGE2 levels in intestinal tissue samples from inflamed and healthy equine intestine. Inflamed tissue MDA and PGE2 levels increased with time after castor oil challenge and correlated with granulocyte infiltration, as determined by myeloperoxidase levels in a companion study. Elevated intestinal tissue MDA levels suggest that lipid peroxidation could be attributed to reactive oxygen metabolites (ROM) released from stimulated, recruited, and resident granulocytes. Tissue levels of MDA and PGE2 suggest a role for granulocyte-derived mediators of int...

Journal of the American Veterinary Medical Association, 1997

Increased popularity during the past decade of brodifacoum, an anticoagulant rodenticide, has led... more Increased popularity during the past decade of brodifacoum, an anticoagulant rodenticide, has led to an increase in cases of accidental poisoning in nontarget species, including pets and farm animals. Pharmacokinetics of second-generation anticoagulant rodenticides such as brodifacoum are substantially different from those of first-generation anticoagulant rodenticides such as warfarin. This difference dramatically influences management of exposure in terms of duration and cost of treatment and may affect outcome. The National Poison Control Center reports that approximately 50 cases of brodifacoum exposure have occurred in horses between 1993 and 1997. To our knowledge, this report is the first complete clinical description of accidental ingestion of a potentially lethal dose of brodifacoum in horses. Early recognition of exposure to brodifacoum, subsequent treatment with adequate doses of vitamin K1, and sequential monitoring of clotting times and serum brodifacoum concentration p...

Journal of the American Veterinary Medical Association, Jan 15, 1989

The Cornell veterinarian, 1992

Two horses with red maple (Acer rubrum) toxicity responded to treatment with high doses of vitami... more Two horses with red maple (Acer rubrum) toxicity responded to treatment with high doses of vitamin C (ascorbic acid), in addition to blood transfusions, and intravenous fluid therapy. The clinical course included Heinz body anemia, marked methemoglobinemia, depression, and evidence of severe tissue anoxia. Clinical recovery was dramatic with stabilization achieved 36 hours following the initiation of ascorbic acid therapy.

Journal of the American Veterinary Medical Association, 1992

A 5-year-old female American Quarter Horse was determined to have immune-mediated hemolytic anemi... more A 5-year-old female American Quarter Horse was determined to have immune-mediated hemolytic anemia after detection of a positive response to a direct Coombs' test. Penicillin-induced immune-mediated hemolytic anemia was confirmed via a direct antiglobulin test, using penicillin-coated RBC. The horse was clinically improved and the anemia resolved in response to supportive care and discontinuation of penicillin treatment. Penicillin should be considered a possible cause of immune-mediated hemolytic anemia in horses.

Equine Veterinary Education, 2009

Equine Veterinary Education, 2010

Equine Veterinary Education, 2010

This article evaluates the European Union (EU)'s border strategy for the Western Balkans. It iden... more This article evaluates the European Union (EU)'s border strategy for the Western Balkans. It identifies an increasing tension between, on the one hand, the Union's use of its border strategy to foster the long-term stabilisation of the countries of the Western Balkans and their future integration into the EU and, on the other hand, the use of border management as an instrument to ensure its own internal security. This tension can be broken down into a threefold contradiction inbuilt into the EU's strategy: short-term vs. long-term objectives; a security vs. development focus; and interventionism vs. local ownership approaches. These contradictions, aggravated by local and regional political, economic and security challenges, can explain existing shortcomings in the EU's border interventions in the Western Balkans.

Equine Veterinary Education, 2010

Equine Veterinary Education, 2010

Robinson's Current Therapy in Equine Medicine, 2015

Robinson's Current Therapy in Equine Medicine, 2015

Veterinary Clinics of North America: Equine Practice, 2007

Journal of Veterinary Internal Medicine, 1997

Persistent hyperammonemia was diagnosed in 2 Morgan fillies with clinical signs that developed ea... more Persistent hyperammonemia was diagnosed in 2 Morgan fillies with clinical signs that developed early in the postweaning period. Diagnostic evaluation, including routine serum chemistries, CBC, liver biopsy, hepatic ultrasonography, liver function test, and necropsy findings did not support a toxic, developmental, or infectious cause. Abnormal serum amino acid and urine orotic acid concentrations suggest that the foals may have had an inherited disorders described in humans as hyperornithinemia, hyperammonemia, and homocitrullinuria (HHH) syndrome. The disorder is thought to be caused by a defective mitochondrial transporter protein, such that ornithine, required for complete urea synthesis, is deficient, thus causing increases in blood ammonia and ornithine concentrations.