Rafael Bruno-Neto - Academia.edu (original) (raw)
Neuroscientist, Biomedical Scientist, Specialist in Behavioral Psychology, Master’s Degree in Neuroscience from Federal University of Santa Catarina and a Doctor’s Degree in Neurology/Neuroscience from Federal University of São Paulo. Working as Associate Professor at State University of Maringá (Paraná-Brazil) from 1988 to 2015 - retired since then. Experience in Human Physiology teaching undergraduate courses in the fields of health and psychology, with emphasis on Medical Physiology, Neurophysiology and General Physiology, working mainly on the following topics: chronobiology, sexuality, epilepsy, neurophysiological mechanisms of development, learning and their disorders. Teacher of general and specific training and Adviser of PDE-SEED/PR, for more than 20 years. I am currently teaching postgraduate courses at specialization level in the areas of Special Education, Psychopedagogy, Neuropedagogy, Neuropsychology, Development and Literacy, Learning Disorders and Intellectual Development Disorders, among others related to neuroscience.http://lattes.cnpq.br/085205853502523
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Possible interactions between the sleep-wakefulness cycle and a new kind of spontaneous epilepsy,... more Possible interactions between the sleep-wakefulness cycle and a new kind of spontaneous epilepsy, expressed as absence-like seizures and spike-wave bursts in FMUSP rats, are evaluated. The electro-oscillograms of some cortical and subcortical regions of the brain were recorded, as well as head, rostrum/vibrissae and eye movements. Recordings were performed uninterruptedly during 24 hours. The seizures were mostly concentrated in the wakefulness state but they could occur in any other phase, including paradoxical sleep. After the seizure, the rats usually returned to the same phase that was interrupted, although they often returned to wakefulness. There was an intense fragmentation of the sleepwakefulness cycle. The incidence of each cycle phase was significantly reduced, except S III of synchronized sleep and paradoxical sleep, thus maintaining the overall duration and architecture of the sleep-wakefulness cycle. The fragmentation of the cycle seems to be due to an impairment of the very processes that generate sleep and wakefulness. Electrophysiological and behavioral profiles of the FMUSP rats recommend accurate and comprehensive study of the animal model owing to its resemblance to seizures in humans and also to discrepancies with existing genetic or experimental epilepsy models.
Acta Scientiarum. Biological Sciences, 2014
Current investigation describes the behavioral and electrographic characteristics of spontaneous ... more Current investigation describes the behavioral and electrographic characteristics of spontaneous absence-like seizures identified in Wistar rats (referred to here as FMUSP-rats, after the
Possible interactions between the sleep-wakefulness cycle and a new kind of spontaneous epilepsy,... more Possible interactions between the sleep-wakefulness cycle and a new kind of spontaneous epilepsy, expressed as absence-like seizures and spike-wave bursts in FMUSP rats, are evaluated. The electro-oscillograms of some cortical and subcortical regions of the brain were recorded, as well as head, rostrum/vibrissae and eye movements. Recordings were performed uninterruptedly during 24 hours. The seizures were mostly concentrated in the wakefulness state but they could occur in any other phase, including paradoxical sleep. After the seizure, the rats usually returned to the same phase that was interrupted, although they often returned to wakefulness. There was an intense fragmentation of the sleepwakefulness cycle. The incidence of each cycle phase was significantly reduced, except S III of synchronized sleep and paradoxical sleep, thus maintaining the overall duration and architecture of the sleep-wakefulness cycle. The fragmentation of the cycle seems to be due to an impairment of the very processes that generate sleep and wakefulness. Electrophysiological and behavioral profiles of the FMUSP rats recommend accurate and comprehensive study of the animal model owing to its resemblance to seizures in humans and also to discrepancies with existing genetic or experimental epilepsy models.
Acta Scientiarum. Biological Sciences, 2014
Current investigation describes the behavioral and electrographic characteristics of spontaneous ... more Current investigation describes the behavioral and electrographic characteristics of spontaneous absence-like seizures identified in Wistar rats (referred to here as FMUSP-rats, after the