Rahil Hasan - Academia.edu (original) (raw)

Papers by Rahil Hasan

Biosensors

Many emerging technologies have the potential to improve health care by providing more personaliz... more Many emerging technologies have the potential to improve health care by providing more personalized approaches or early diagnostic methods. In this review, we cover smartphone-based multiplexed sensors as affordable and portable sensing platforms for point-of-care devices. Multiplexing has been gaining attention recently for clinical diagnosis considering certain diseases require analysis of complex biological networks instead of single-marker analysis. Smartphones offer tremendous possibilities for on-site detection analysis due to their portability, high accessibility, fast sample processing, and robust imaging capabilities. Straightforward digital analysis and convenient user interfaces support networked health care systems and individualized health monitoring. Detailed biomarker profiling provides fast and accurate analysis for disease diagnosis for limited sample volume collection. Here, multiplexed smartphone-based assays with optical and electrochemical components are covered...

Sensing Tools and Techniques for COVID-19

Biosensors and Bioelectronics: X

Handbook of Oxidative Stress in Cancer: Therapeutic Aspects, 2022

Process Biochemistry, 2020

Abstract Ovarian cancer refers to a cancer that forms inside or on the surface of an ovary. It re... more Abstract Ovarian cancer refers to a cancer that forms inside or on the surface of an ovary. It results in the abnormal growth of cells that can attack or spread to other parts of the body. According to the reports, early detection can minimize the risk of mortality and can lead to effective management of the disease. Though, recently used methods can only enable to detect the cancer at an advanced stage. Therefore, rapid and effective approaches for detecting ovarian cancer are urgently in demand. Researchers are fascinating towards an effective portable and early detection technique for the diagnosis of ovarian cancer. Biosensors are best alternative to afore mentioned demand as they are designed for detecting a particular biotic analyte by converting a biological entity such as antibody, blood, cell, etc. into an electronic signal that can be measured and analyzed. Biosensor technology can accommodate rapid and precise diagnosis of cancer-related cells and deliver an improved approach for making them sensitive and specific. Furthermore, choice of biomarkers also plays an important role in determining the stage of cancer. This review summarizes the classification of ovarian cancer, biomarkers and techniques employed for the detection of ovarian cancer. Besides, some of the future outlooks of bio sensing technology are also discussed.

Process Biochemistry, 2021

Abstract Mosquito-borne flavivirus is associated with the zika virus (ZIKV) which is the attentio... more Abstract Mosquito-borne flavivirus is associated with the zika virus (ZIKV) which is the attention of numerous public health hazards & enduring epidemic for many years and was first identified in 1947. Formerly partial to sporadic cases in Asia & Africa but in Brazil, the zika virus appearance in 2015 indicated fast spreading all over Americans. It has been acknowledged as a global public health emergency by the World Health Organization (WHO) in 2016. Symptoms normally appear as mild-influenza, neurological signs, and subclinical manifestations with the syndrome of microcephaly in offspring that are born from infected mothers & Guillain-Barre syndrome (GBS) in adults. There is no cure or effective Zika Virus treatment known to date. Easy and efficient detection of the zika virus can reduce the risk of sickness and the successful management of this disease. Conventional techniques currently available are focused on clinical manifestation, along with molecular and serological detection tools that can identify the zika virus but due to their various disadvantages such as low specificity and sensitivity, there is a need for a quick and easy approach for the diagnosis of zika virus. Scientists are showing great interest in an effective portable and simple detection method to diagnose the Zika virus. Biosensor is considered a viable advanced system that can meet all the aforementioned demands. Biosensors are combined with an effortless approach to allow them for exploiting in various applications. This review summarizes the diagnosis, surveillance, and advancement in sensing technology for easy and successful detection of Zika virus and its usage as a fast and rapid analytical tool.

Biomedical Engineering Advances, 2021

Human cytomegalovirus (HCMV) is a beta herpes-virus, which affects human being as a lifelong infe... more Human cytomegalovirus (HCMV) is a beta herpes-virus, which affects human being as a lifelong infection. HCMV is the prominent cause for the infections of congenital with a 1.0-2.4% incidence of live-births, along with possible severe classic cytomegalovirus. Crucial HCMV infection is usually asymptomatic in healthy hosts but it can cause severe or sometimes fatal illness in immuno-compromised neonates and individuals. Various conventional methods such as PCR, virus isolation, antigenemia test, histological and serological are available for detection of HCMV. Among all the analytical techniques, biosensors clinched as the most advanced technology, which offers many features such as simplicity, inexpensive, highly sensitive, and effective approach. The future of diagnosis will rely on the development of point-of-care devices, which can be used at the site of need, resource-restricted settings, and provides affordability. This review describes various analytical methods for the detection of HCMV emphasizing biosensing methods.

Functionalized Nanomaterials Based Devices for Environmental Applications, 2021

Abstract Advancements in nanotechnology have led to the discovery of a miniaturized device called... more Abstract Advancements in nanotechnology have led to the discovery of a miniaturized device called lab-on-a-chip (LOC). An LOC device incorporates one or many laboratory tasks onto a single integrated circuit only millimeters to a few centimeters in size (i.e., a single piece of glass or plastic chip). The small size of the device helps in attaining high throughput screening and automation. LOC devices are rapid, easy-to-use, and portable systems for applications in point-of-care (POC) diagnostics, biomolecules analysis, forensics, food and drugs development, and environmental analysis. LOC devices represent a fast developing field due to their advantages of low wastage, less requirement of sample volume, cost-effectiveness, fast results, and portability. The main challenge in the development of LOC devices is fabricating and designing the devices on a minor scale so that they are functional, efficient, and cost-effective. In recent years, advances in nanomaterials and nanofabrication methods have allowed for the extensive manufacture of LOC devices. This chapter presents the latest developments in fabrication and production methods as well as potential applications of LOC devices.

Sensors International, 2020

Recent remarkable advances in the field of nanotechnology has been achieved in the last few years... more Recent remarkable advances in the field of nanotechnology has been achieved in the last few years especially in the fabrication of sensors that have wide number of applications. Nanomaterials are the foundation of nanotechnology that are measured on nanoscale. Carbon nanotubes (CNTs) are tube-like materials that are made up of carbon with a diameter calculating on a nanometer scale. They are originated from graphite sheet and these graphite layers seems similar to a rolled up non-stop unbreakable hexagonal like mesh structure and the carbon molecules appears at the apexes of the hexagonal structures. Depending upon the number of carbon layers, carbon nanotubes can be single-walled carbon nanotubes (SWCNTs), double-walled carbon nanotubes (DWCNTs) and multi-walled carbon nanotubes (MWCNTs). Carbon nanotubes (CNTs) can be fabricated by three main methods i.e., chemical vapor deposition, electric arc method and laser deposition method. Carbon nanotubes exhibit various characteristic properties such as high elasticity, high thermal conductivity, low density and they are chemically more inert etc. Due to these interesting properties, carbon nanotubes have played a significant role in the field of nanotechnology, electronics, optics and other fields of materials science. Carbon nanotubes are being positively applied in drug delivery, sensing, water treatment etc. Functionalization of their surface can result in highly soluble materials, which can be further derivatized with active molecules, making them compatible with biological systems. Surface functionalization enables adsorption or attachment of various molecules or antigens, which subsequently can be targeted to the desired cell population for immune recognition or a therapeutic effect. In this review, properties of carbon nanotubes and their clinical applications such as medical diagnostics and drug delivery are being discussed. Here, antibacterial as well as antifungal activity of carbon nanotubes are also being reviewed.